Zolfrac 5mg/100ml Injection
By Zolfrac
Rx
1 Injection in a Vial

Composition
Zoledronic acid(5mg/100ml)

Manufacturer - Intas Pharmaceuticals Ltd
Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Expires on or after
April, 2027
About Zolfrac 5mg/100ml Injection
Zolfrac 5mg/100ml Injection, containing Zoledronic Acid, is categorized under Bisphosphonates and is utilized to address osteoporosis associated with menopause, steroid use, and high calcium levels in cancer patients. Osteoporosis is a condition that leads to bone weakening, often affecting women post-menopause and occasionally in adult men. Paget's disease of the bone, another condition addressed by Zolfrac 5mg/100ml Injection, is a chronic disorder that disturbs the normal bone regeneration cycle.
The administration of Zolfrac 5mg/100ml Injection is typically performed by a healthcare professional, with dosages and frequency tailored to individual patient requirements. Patients may receive either a single injection or a series of injections based on their specific medical condition. To maximize the benefits of the medication, patients are advised to drink ample water before the injection to prevent dehydration. The complete therapeutic effects of Zolfrac 5mg/100ml Injection may take several days to manifest fully. Treatment with this drug is generally part of a broader therapy plan that may involve dietary modifications and the incorporation of calcium and vitamin supplements.
Patients should be cautious of potential side effects which include nausea, fatigue, anemia, bone pain, constipation, fever, vomiting, and breathlessness. Notably, severe kidney issues can occur with Zolfrac 5mg/100ml Injection, particularly in dehydrated individuals, those on diuretic medication, or with pre-existing kidney diseases. Additionally, low blood calcium levels and mouth/jaw pain are possible serious side effects that necessitate immediate medical attention.
It is essential to disclose relevant medical information to your healthcare provider before commencing treatment with Zolfrac 5mg/100ml Injection, such as kidney problems, low calcium levels, and current medications. Patients are advised to avoid this medication during pregnancy or breastfeeding. Regular monitoring of kidney function and calcium levels through medical tests may be necessary. Smoking and excessive alcohol consumption are discouraged as they can contribute to bone health deterioration.
Benefits
Zolfrac 5mg/100ml Injection offers several benefits for different conditions. In the case of osteoporosis, a common condition that weakens bones especially in women after menopause, Zyrona is a bisphosphonate medicine that works by slowing down the breakdown of bones in the body. By maintaining bone density, Zyrona reduces the risk of bone fractures. This injection is typically administered once a year for osteoporosis treatment and once every two years for prevention. Along with medication, lifestyle changes like regular weight-bearing exercise, consumption of calcium-rich foods, and Vitamin D supplementation can further improve bone strength.
For individuals suffering from hypercalcemia, a condition characterized by excessive calcium levels in the blood, Zolfrac 5mg/100ml Injection is effective in reducing calcium levels by slowing down bone breakdown. Particularly prevalent in cancer patients, hypercalcemia can be serious and requires immediate attention. Zyrona is usually given as a one-time injection for this condition, with the possibility of additional doses as prescribed by the healthcare provider. It is important to attend all scheduled appointments with the doctor for proper management. Engaging in regular physical activity, especially weight-bearing exercises, is recommended to help alleviate hypercalcemia symptoms. Avoiding calcium and vitamin D3 supplements, as well as reducing their intake through diet, can also contribute to better management of the condition.
Overall, Zolfrac 5mg/100ml Injection provides relief and management options for both osteoporosis and hypercalcemia, promoting better bone health and reducing the risk of fractures and complications associated with these conditions. It is important to follow the prescribed dosage and recommendations from your healthcare provider to achieve the best results.
How to use the Zolfrac 5mg/100ml Injection
To use Zolfrac 5mg/100ml Injection, you should have a doctor or nurse administer the medicine to you. It is important not to try to administer the injection yourself. This medication needs to be given by a healthcare professional who is trained to do so. Before you receive the injection, the healthcare provider will ensure that it is the right dose for you and will administer it correctly. By following this guidance, you can ensure that the Zolfrac 5mg/100ml Injection is given safely and effectively. Remember, always seek professional help for administration of this medication to avoid any risks or complications.
Uses of Zolfrac 5mg/100ml Injection
Zolfrac 5mg/100ml Injection is primarily used for treating osteoporosis, a condition characterized by weak and brittle bones that are more prone to fractures. This injection helps in increasing bone strength and reducing the risk of fractures in individuals with osteoporosis. Additionally, Zolfrac 5mg/100ml Injection is also effective in managing hypercalcemia, a condition marked by high levels of calcium in the blood. By normalizing calcium levels, this injection helps in addressing the symptoms associated with hypercalcemia, such as kidney stones, abdominal pain, and fatigue.
What conditions Zolfrac 5mg/100ml Injection treats?
Zolfrac 5mg/100ml Injection is used to treat osteoporosis, a condition where bones become weak and brittle, increasing the risk of fractures, especially in postmenopausal women. This medicine, a bisphosphonate, slows down bone breakdown to maintain bone density and prevent fractures. It is also used to treat hypercalcemia, high calcium levels in the blood often seen in cancer patients. Zyrona helps reduce blood calcium levels by inhibiting bone breakdown. Proper hydration is essential with this medicine. Adverse effects may include nausea, fatigue, anemia, bone pain, and kidney issues. Regular exercise, calcium-rich diet, and avoidance of alcohol and tobacco can help improve bone strength. Careful monitoring and medical attention are crucial due to potential serious side effects.
Should you consult a doctor?
If you experience serious side effects such as kidney problems, low calcium levels in the blood, mouth or jaw pain while taking Zolfrac 5mg/100ml Injection, you should seek urgent medical attention. It is important to inform your doctor if you notice these symptoms. Additionally, if you are pregnant or breastfeeding, do not use this medication. Consult your doctor before starting treatment if you have kidney issues or low calcium levels. Inform your doctor about all medications you are taking, especially those for severe infections, cancer, or osteoporosis, as they may interact with Zyrona injection. Regular medical tests may be required to monitor kidney function and calcium levels. Avoid smoking and excessive alcohol consumption, as they can negatively impact bone health. Remember that most common side effects like headache, back pain, nausea, and fatigue generally subside on their own as your body adjusts to the medication, but consult your doctor if they persist or if you have concerns.
Side effects of Zolfrac 5mg/100ml Injection
When using Zolfrac 5mg/100ml Injection, some individuals may experience side effects. Most of these side effects are not severe and usually subside as your body gets used to the medication. However, if any of these side effects persist or become a concern, it is important to consult your doctor. Common side effects include headaches, back pain, musculoskeletal pain (affecting bone, muscles, or joints), heartburn, diarrhea, nausea, breathlessness, fatigue, constipation, bone pain, vomiting, fever, and anemia (low red blood cell count). It is essential to monitor any symptoms you may experience and seek medical advice if needed.
Safety advice

liver
Limited information is accessible regarding the application of Zolfrac 5mg/100ml Injection in individuals with liver conditions. It is strongly recommended to seek guidance from your healthcare provider before proceeding with the usage of this medication.

kidney
Limited information is available on using Zolfrac 5mg/100ml Injection in patients with kidney disease. Please consult your doctor.

alcohol
Caution is recommended when drinking alcohol with Zolfrac 5mg/100ml Injection. Make sure to check with your doctor.

driving
Zolfrac 5mg/100ml Injection may reduce alertness, impact vision, or cause drowsiness and dizziness. Do not drive if experiencing these effects.

pregnancy
Zolfrac 5mg/100ml Injection is not recommended during pregnancy due to potential risks to the developing baby. However, in life-threatening situations, a doctor may prescribe it after careful consideration of the benefits and risks. Consult your doctor for guidance.

breastfeeding
Zolfrac 5mg/100ml Injection is likely unsafe for breastfeeding. Limited data suggests potential harm to the baby through breastmilk exposure.
Consumption warning before consuming Zolfrac 5mg/100ml Injection
Before using Zolfrac 5mg/100ml Injection, it is important to be aware of certain precautions. This medicine is primarily prescribed for conditions like osteoporosis and high calcium levels in cancer patients. Administration should be carried out by a healthcare professional, and the dosage will be determined by your doctor based on your individual needs. Adequate water intake is advised before the injection to prevent dehydration. It may take time before the full benefits are seen.
Common side effects such as nausea, fatigue, and bone pain may occur. However, Zyrona can also lead to severe kidney issues, especially in dehydrated individuals or those with existing kidney problems. Low calcium levels and mouth or jaw pain are serious side effects requiring immediate medical attention. This medication is not suitable for pregnant or breastfeeding individuals and caution is necessary if you have kidney issues or low calcium levels. Inform your doctor about all medications being taken, as certain drugs can interact with Zyrona.
Regular medical tests may be needed to monitor kidney function and calcium levels while using Zyrona. Smoking and excessive alcohol consumption should be avoided as they can worsen bone health.
What if you forgot to take Zolfrac 5mg/100ml Injection?
If you forget to take a dose of Zolfrac 5mg/100ml Injection, it is important to seek advice from your doctor. It is crucial to consult your healthcare provider for guidance on the best course of action to take when a dose has been missed. It is recommended to not try to catch up on missed doses by doubling up on the next dose, as this can lead to potential complications. Your doctor will be able to provide personalized instructions on how to proceed if you miss a dose of Zolfrac 5mg/100ml Injection, ensuring the best outcome for your treatment plan.
Related lab tests
The Related Lab Tests for Zolfrac 5mg/100ml Injection include tests for Calcium and Intact Parathyroid Hormone. These lab tests are important to monitor the levels of these substances in the body after administration of the injection. A test for Calcium helps to assess the overall calcium balance in the body, which is crucial for maintaining healthy bones, teeth, muscles, and nerve function. Meanwhile, the Intact Parathyroid Hormone test measures the levels of the hormone produced by the parathyroid glands, which play a key role in regulating calcium and phosphorus levels in the body. Monitoring these lab tests can help healthcare providers ensure that the Zyrona injection is having the desired effect and is not causing any imbalances in these important substances.
Additional Information
| Habit Forming | No |
| Chemical Class | Bisphosphonate Derivative |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Bone resorption inhibitor -Bisphosphonates |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹3815
Inclusive of all taxes
Content verified by

Dr. Monie Riju Simon
MBBS - General Medicine
Last update on 11-Feb-2025
