Zolephos 5mg/100ml Infusion
By Zolephos
Rx
100ml Infusion in a Bottle

Composition
Zoledronic acid(5mg/100ml)

Manufacturer - Abbott
16th Floor, Godrej BKC, Plot – C, "G" Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Expires on or after
May, 2026
About Zolephos 5mg/100ml Infusion
Zolephos 5 mg Infusion 100 ml is a bisphosphonate medication used to treat osteoporosis, particularly in post-menopausal women or individuals on long-term steroid therapy. It is also effective in managing Paget's bone disease and high levels of calcium associated with cancer. Osteoporosis is a condition where bones become weak and brittle due to decreased bone density, making them more prone to fractures. Zolephos 5 mg Infusion 100 ml contains Zoledronic acid, which works by binding tightly to bones, preventing the removal of calcium by osteoclasts, the cells that break down bone tissue. This process helps maintain bone strength and reduces the risk of fractures.
Zolephos 5 mg Infusion 100 ml is administered by a healthcare professional, and the dosage and frequency will be determined by your doctor based on your specific condition. Before the infusion, your doctor may advise you to drink plenty of water to prevent dehydration. It may take several days before the full benefits of the medication are realized. Along with Zolephos 5 mg Infusion 100 ml, your treatment plan may include dietary changes and the use of calcium and vitamin supplements.
Common side effects of Zolephos 5 mg Infusion 100 ml may include nausea, fatigue, anemia, bone pain, constipation, fever, vomiting, and breathlessness. It can also lead to serious kidney issues, especially in dehydrated individuals or those with pre-existing kidney conditions. Severe side effects such as low calcium levels in the blood or jaw pain require immediate medical attention. It is important to inform your doctor if you experience any concerning symptoms.
Before using Zolephos 5 mg Infusion 100 ml, it is vital to disclose any existing kidney problems, low calcium levels, or other medications you are taking. Pregnant or breastfeeding individuals should not receive this medication. Additionally, Zolephos 5 mg Infusion 100 ml is not recommended for children under 18 years old. Lifestyle factors such as smoking and excessive alcohol consumption can impact bone health and should be avoided. Driving should be done cautiously as Zolephos 5 mg Infusion 100 ml may cause dizziness. If you notice any issues with your teeth or mouth, such as pain or swelling, seek medical advice promptly as these could be signs of a rare condition called osteonecrosis of the jaw.
Benefits
Zolephos 5mg/100ml Infusion is a powerful medication that offers various benefits for individuals dealing with osteoporosis and hypercalcemia. For those suffering from osteoporosis, a condition that leads to weaker and more fragile bones, Zolephos 5mg/100ml Infusion serves as a valuable treatment option. As a bisphosphonate medication, it works by slowing down the breakdown of bone in the body, thereby maintaining bone density and lowering the risk of fractures. Administered once a year for osteoporosis treatment and every two years for prevention, Zolephos 5mg/100ml Infusion is an effective way to enhance bone strength and reduce the likelihood of bone injuries.
Moreover, in cases of hypercalcemia, a serious condition characterized by excessive calcium in the blood, Zolephos 5mg/100ml Infusion acts as a crucial treatment method. By inhibiting the rate at which bone breakdown occurs in the body, this medication helps lower the calcium levels in the blood. This is particularly beneficial for individuals with cancer-related hypercalcemia, where elevated calcium levels can pose significant health risks. Zolephos 5mg/100ml Infusion works by binding tightly to the bone, preventing osteoclasts from removing calcium and thus supporting bone strength. Additionally, it hinders the reabsorption of calcium from bones into the bloodstream, aiding in the management of high blood calcium levels caused by cancer.
In summary, Zolephos 5mg/100ml Infusion offers a dual benefit of strengthening bones and regulating calcium levels, making it a valuable treatment option for individuals grappling with osteoporosis and hypercalcemia. By following the recommended dosage and incorporating healthy habits such as exercise and balanced nutrition, patients can maximize the positive outcomes of Zolephos 5mg/100ml Infusion and improve their overall bone health.
How to use the Zolephos 5mg/100ml Infusion
To use Zolephos 5mg/100ml Infusion, you need to have a healthcare professional administer it. This medicine comes in the form of a 100 ml infusion with a strength of 5 mg. It is crucial that you do not try to administer this medication yourself. Your doctor or nurse will be responsible for giving you the infusion, so it is important to follow their instructions carefully. Do not attempt to self-administer Zolephos 5mg/100ml Infusion to ensure safety and proper dosage. Always rely on the expertise of healthcare professionals when using this medication.
Uses of Zolephos 5mg/100ml Infusion
Zolephos 5mg/100ml Infusion is used to treat various conditions such as osteoporosis in postmenopausal women, Paget’s disease, and hypercalcemia associated with cancer. Osteoporosis is a condition characterized by weak and brittle bones, especially common in women after menopause. Paget's disease is a chronic bone disorder that can result in enlarged and misshapen bones. Hypercalcemia, which is having high levels of calcium in the blood, can occur in individuals with certain types of cancer. Zolephos 5mg/100ml Infusion is beneficial in managing these conditions effectively.
What conditions Zolephos 5mg/100ml Infusion treats?
Osteoporosis is a bone disease that weakens bones by reducing bone density. Post-menopausal women are more at risk as their estrogen levels decrease after menopause, causing bone loss. Long-term use of steroids can also lead to osteoporosis. Symptoms include back pain, loss of height, stooped posture, and bones breaking easily. Paget's disease involves quick but disordered bone remodeling, leading to weakened bones. Hypercalcemia in cancer, seen in breast, lung, or blood cancer, results in high blood calcium levels causing symptoms like nausea and loss of appetite.
Should you consult a doctor?
If you experience serious side effects of Zolephos 5mg/100ml Infusion such as kidney problems, low calcium levels in the blood, or pain in the mouth or jaw, you should seek urgent medical attention. These are signs that need immediate care. Additionally, if you are pregnant or breastfeeding, do not take this medication and consult your doctor. Inform your healthcare provider if you have kidney issues, low calcium levels, or are taking other medications. It is important to notify your doctor about any alarming symptoms you may encounter while taking Zolephos 5mg/100ml Infusion. Remember, avoiding dehydration, smoking, and excessive alcohol consumption is crucial for maintaining bone health and ensuring the effectiveness of the treatment. If mild side effects like headache, back pain, heartburn, or diarrhea persist or cause worry, do consult your doctor for guidance. Your healthcare provider can offer support and advice to address any concerns you may have during your Zolephos 5mg/100ml Infusion treatment.
Side effects of Zolephos 5mg/100ml Infusion
When undergoing Zolephos 5mg/100ml Infusion, some individuals may experience mild side effects that typically do not necessitate medical intervention and tend to fade as the body becomes accustomed to the medication. These side effects could include headaches, back pain, musculoskeletal pain (affecting bones, muscles, or joints), heartburn, diarrhea, nausea, breathlessness, fatigue, constipation, bone pain, vomiting, fever, and anemia (characterized by a low count of red blood cells). Other possible side effects may encompass dizziness, flu-like symptoms such as chills, tiredness, muscle, and joint pain, as well as pain in muscles, joints, or bones. Additionally, individuals might observe swelling or experience pain at the site of infusion. It is advisable to consult a healthcare provider if these side effects persist or cause concern.
Safety advice

liver
Limited information is available regarding the use of Zolephos 5mg/100ml Infusion in patients with liver disease. It is important to consult with your doctor before using this medication to ensure it is safe for your specific condition.

kidney
Limited data exists on Zolephos 5mg/100ml Infusion use for kidney disease. Consult your doctor for guidance.

alcohol
When taking Zolephos 5mg/100ml Infusion, be cautious about consuming alcohol. It's advisable to consult your doctor before doing so.

driving
While using Zolephos 5mg/100ml Infusion, be cautious about driving as it can reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if you experience these symptoms.

pregnancy
Zolephos 5mg/100ml Infusion should not be used during pregnancy, as there is clear evidence of harm to the unborn baby. Only in severe, life-threatening cases would a doctor consider its use after weighing the risks against the benefits. Consult your doctor before use.

breastfeeding
Zolephos 5mg/100ml Infusion is not recommended for use during breastfeeding, as limited human data indicates a risk of the drug passing into breastmilk and potentially harming the baby.
Consumption warning before consuming Zolephos 5mg/100ml Infusion
Before consuming Zolephos 5mg/100ml Infusion, it is crucial to be aware of certain warnings. Inform your doctor if you are allergic to Zolephos 5mg/100ml Infusion or any other medications. Pregnant or breastfeeding individuals should avoid this infusion without consulting a doctor. Children under 18 years should not take this medication due to uncertain safety and effectiveness. Individuals with hypocalcemia, severe kidney problems, or those prone to dizziness should steer clear of Zolephos 5mg/100ml Infusion. Smoking patients must inform their doctor beforehand, as dental risks may increase. Be vigilant for signs of osteonecrosis of the jaw (ONJ) such as loose teeth, swelling, or pain in the mouth, and promptly consult your doctor and dentist if any occur. To prevent dehydration, drink at least 2 glasses of fluids before and after treatment, and take calcium and vitamin D supplements as prescribed.
What if you forgot to take Zolephos 5mg/100ml Infusion?
If you forget to take a dose of Zolephos 5mg/100ml Infusion, it's important to seek guidance from your doctor. Ensuring you follow your prescribed dosage is essential for the effectiveness of the treatment. Consulting with your healthcare provider will help you determine the best course of action to make up for the missed dose and maintain the intended treatment schedule. Your doctor will provide you with specific instructions tailored to your situation to ensure that the treatment remains on track.
Related lab tests
When monitoring the effects of Zolephos 5mg/100ml Infusion, it's important to conduct certain related lab tests to ensure that the treatment is working as expected. Two key tests to consider are calcium levels and intact parathyroid hormone levels. Calcium levels help determine the amount of calcium in the blood, which is essential for various bodily functions including bone health and muscle contractions. Intact parathyroid hormone levels indicate how well the parathyroid glands are functioning, which play a crucial role in regulating calcium levels in the body. Monitoring these lab tests can provide valuable information on the efficacy of Zolephos 5mg/100ml Infusion and guide treatment decisions.
Additional Information
Habit Forming | No |
Chemical Class | Bisphosphonate Derivative |
Therapeutic Class | PAIN ANALGESICS |
Action Class | Bone resorption inhibitor -Bisphosphonates |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹3993
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Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024