Zoladex 3.6 Injection
By Zoladex
Rx
1 Injection in a Vial

Composition
Goserelin acetate(3.6mg)

Manufacturer - AstraZeneca
Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Expires on or after
August, 2025
About Zoladex 3.6 Injection
Zoladex 3.6 Injection is a medication used to treat various conditions such as prostate cancer in men, breast cancer, endometriosis, uterine fibroids in women, and female infertility in combination with other medicines. It is administered as an injection under the skin by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency based on your condition, which may change over time. It is crucial to follow your doctor's instructions carefully to avoid serious side effects.
Common side effects of Zoladex 3.6 Injection include hot flashes, sexual dysfunction, decreased libido, and urinary tract disorders. Prolonged use of the medication may lead to weakened bones and reduced bone mineral density, for which it is recommended to take vitamin D and calcium supplements. Women may experience vaginal bleeding initially, which usually resolves on its own. It is important to consult your doctor if this persists or causes concern.
Before starting Zoladex 3.6 Injection, inform your doctor if you have a history of alcohol consumption or diabetes. Additionally, disclose all medications you are currently taking, as certain medications may interact with or be affected by Zoladex. This medication is not advised during pregnancy or breastfeeding, and effective contraception is recommended for both men and women during treatment.
ZOLADEX LA 10.8MG, containing Goserelin, is classified as a Luteinising hormone-releasing hormone (LHRH) analogue and is used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and infertility in combination with other medications. Goserelin functions as a long-acting GnRH agonist, inhibiting the production of luteinizing hormone and subsequently affecting the release of testosterone in men and estrogen in women. This disruption in hormone levels hinders the growth of hormone-dependent cancer cells.
It is essential to communicate any liver, kidney, or heart problems to your doctor before receiving ZOLADEX LA 10.8MG. This medication is not suitable for use in children, pregnant women, or breastfeeding mothers. ZOLADEX LA 10.8MG is typically administered subcutaneously on the stomach every four weeks, with common side effects including hot flashes, sweating, decreased sex drive, and bone thinning.
Do let me know if you need more information on this drug or any other related topics.
Benefits
Zoladex 3.6 Injection offers various benefits in treating different medical conditions. In prostate cancer, this medication works by reducing testosterone levels in men, which helps to slow down or halt the growth of cancer cells. By doing so, it eases difficulties with urination commonly experienced with prostate cancer, making it easier for men to urinate.
For breast cancer, Zoladex 3.6 Injection is effective in alleviating symptoms such as breast lumps, abnormal nipple discharge, or changes in breast texture. It targets hormones necessary for breast cancer growth, potentially inhibiting its progression. Additionally, the injection may interfere with other hormones or directly impact cancer cells to impede further growth.
In endometriosis, a condition where uterine lining tissue grows elsewhere, this medication helps manage symptoms like pelvic pain, menstrual cramps, and infertility issues. Zoladex 3.6 Injection regulates the growth of uterine lining and endometrial tissues, offering relief from these distressing symptoms. Consistent use is essential for optimal effectiveness, though additional treatments or procedures may be recommended to better control endometriosis.
Moreover, for uterine fibroids, non-cancerous growths in the uterus, Zoladex 3.6 Injection aids in controlling associated symptoms like heavy menstrual bleeding and lower back pain. It inhibits the enzyme responsible for fibroid growth, resulting in a reduction in size and preventing further enlargement of these growths. Adhering to your doctor's instructions when taking this medication is crucial to reap its full benefits.
Lastly, in cases of female infertility, Zoladex 3.6 Injection is part of a treatment regimen to address infertility by regulating ovulation. By controlling the release of eggs from the ovaries, this injection enhances the chances of conception when used in conjunction with other prescribed medications. It is essential to follow your healthcare provider's guidance for optimal outcomes.
Overall, Zoladex 3.6 Injection provides targeted relief for prostate cancer, breast cancer, endometriosis, uterine fibroids, and female infertility, helping patients manage symptoms and potentially improve their quality of life.
How to use the Zoladex 3.6 Injection
When it comes to using Zoladex 3.6 Injection, it's important to remember that only your doctor or nurse should administer the medication - never try to do it yourself. The injection is typically given under the skin on your stomach, and this should be done every four weeks, which is equivalent to every 28 days. This regular schedule ensures the medication is effective in managing your condition. Make sure to follow your healthcare provider's instructions carefully and attend all scheduled appointments for the injections. If you have any questions or concerns about the administration of Zoladex 3.6 Injection, don't hesitate to discuss them with your healthcare team for guidance and support.
Uses of Zoladex 3.6 Injection
Zoladex 3.6 Injection is used in the treatment of prostate cancer in men and also for breast cancer, endometriosis, uterine fibroids, and female infertility. It is an effective medication for managing these conditions and helping patients improve their health. This injection plays a crucial role in addressing the specific health needs of individuals suffering from prostate cancer, breast cancer, endometriosis, uterine fibroids, and female infertility. The diverse applications of Zoladex 3.6 Injection make it a valuable treatment option for a range of conditions affecting both men and women.
What conditions Zoladex 3.6 Injection treats?
Zoladex 3.6 Injection is prescribed to treat various conditions such as prostate cancer in men, breast cancer, endometriosis, uterine fibroids, and female infertility. For prostate cancer, it works by reducing testosterone levels to slow down cancer cell growth and improve urination. In breast cancer, it helps by impacting hormone production critical for cancer growth. In endometriosis, it prevents excessive tissue growth, relieving symptoms like pain and discomfort. For uterine fibroids, it reduces fibroid size and symptoms. In female infertility, it assists in controlling egg release for fertility treatment.
Should you consult a doctor?
It is important to seek medical advice before using Zoladex 3.6 Injection if you have a history of high blood pressure, difficulties passing urine, back issues, diabetes (in men), or osteoporosis. These conditions may require special attention or monitoring while using this injection. Inform your doctor about any of these conditions to ensure safe and effective treatment. If you experience any new or worsening symptoms related to these conditions after starting the injection, seek immediate medical attention. Consulting your healthcare provider promptly can help manage any potential complications and ensure your well-being during the treatment with Zoladex 3.6 Injection.
Side effects of Zoladex 3.6 Injection
Zoladex 3.6 Injection may cause various side effects. These side effects are usually temporary and may go away as your body gets used to the medication. However, if these side effects persist or concern you, it is important to consult your doctor. Some common side effects include decreased libido, erectile dysfunction, and depression. You may also experience headaches, dizziness, nausea, and high blood pressure. Other possible side effects include breast atrophy, pain during sexual intercourse, hot flushes, and sexual dysfunction. Urinary tract disorders, lethargy, pain, and edema (swelling) are also potential side effects of this injection. Additionally, you might encounter upper respiratory tract infections, rashes, sweating, and decreased appetite. More severe side effects could include chronic obstructive pulmonary disease (COPD), heart failure, insomnia, vaginal inflammation, emotional lability, and acne. Some individuals may also experience breast enlargement, pelvic discomfort, and reactions at the injection site such as burning, irritation, itching, and redness. Pain during periods and uterine bleeding are among the other possible side effects of Zoladex 3.6 Injection. It is essential to pay attention to any changes and report them to your healthcare provider for proper guidance and management.
Safety advice

liver
Zoladex 3.6 Injection is considered safe for use in patients with liver disease. There is no need for any adjustments to the dosage of Zoladex 3.6 Injection specifically for individuals with liver issues. This information suggests that Zoladex 3.6 Injection can be used without concerns regarding its impact on the liver.

kidney
Zoladex 3.6 Injection is safe for use in patients with kidney disease. No need to adjust the dose for kidney issues.

alcohol
It is uncertain if consuming alcohol with Zoladex 3.6 Injection is safe. It is advisable to consult your doctor for guidance.

driving
Zoladex 3.6 Injection generally does not impact your driving ability.

pregnancy
Zoladex 3.6 Injection is not safe to use during pregnancy. Consult your doctor as it can cause serious harm to the developing baby based on studies on pregnant women and animals.

breastfeeding
Caution is advised when using Zoladex 3.6 Injection while breastfeeding since limited data suggests it may pass into breastmilk and potentially harm the baby.
Consumption warning before consuming Zoladex 3.6 Injection
Before consuming Zoladex 3.6 Injection, it is crucial to be aware of certain important information for your safety. This medication is primarily used to treat prostate cancer in men and conditions like breast cancer, endometriosis, uterine fibroids, and female infertility. It is administered via injection under the skin by a qualified healthcare professional, and the dosage and frequency will be determined by your doctor based on your condition.
Taking Zoladex 3.6 Injection incorrectly or in higher quantities than prescribed can lead to severe side effects. It may take some time before you start to notice improvements, so it is essential to follow your doctor's instructions closely and not discontinue the medication without their guidance. Common side effects include hot flashes, sexual dysfunction, and urinary issues.
Long-term use of this medication may weaken bones, so it is recommended to take vitamin D and calcium supplements while on treatment. Women may experience initial vaginal bleeding, which typically resolves on its own. Prior to starting Zoladex 3.6 Injection, inform your doctor about any history of alcohol consumption, diabetes, or other medications you are taking to prevent any potential interactions. It is crucial to use effective contraception during treatment to avoid pregnancy, as this medicine is not advised during pregnancy or breastfeeding.
Related lab tests
When considering lab tests related to Zoladex 3.6 Injection, there are several relevant tests to keep in mind. Firstly, Anti Mullerian Hormone (AMH) test may be important as it provides information about ovarian reserve, which can be impacted by certain medications including Zoladex 3.6 Injection. Secondly, tests related to Breast Cancer such as CA 15.3, Estrogen Receptor (ER), and Progesterone Receptor (PR) status are crucial for monitoring any potential breast cancer risk or progression. Additionally, Glycosylated Hemoglobin test, also known as HbA1c, is significant in assessing long-term blood sugar control in diabetic patients who may be receiving Zoladex 3.6 Injection, as this medication can affect glucose levels.
Moreover, Prostate health monitoring is essential for individuals on this medication, making Prostate Specific Antigen (PSA) tests - both Free and Total PSA - important for evaluating prostate function and screening for prostate cancer. Testosterone Total test is another valuable assessment for individuals undergoing treatment with Zoladex 3.6 Injection, as it can impact hormone levels. Finally, Thyroid Stimulating Hormone (TSH) test is relevant as it helps in assessing thyroid function, which can be affected by certain medications including Zoladex 3.6 Injection. It is advisable to consult with a healthcare provider to determine the frequency and necessity of these lab tests based on individual health conditions and treatment plans.
Additional Information
Habit Forming | No |
Chemical Class | GNRH Analogue |
Therapeutic Class | - |
Action Class | GNRH agonists/analogue |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 11-Feb-2025