Yondelis Injection
By Yondelis
Rx
1 Injection in a Vial

Composition
Trabectedin(1mg)

Manufacturer - Janssen Pharmaceuticals
Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060

Expires on or after
August, 2026
About Yondelis Injection
Yondelis Injection is a medication used to treat certain types of cancers. It is specifically used in patients with advanced soft tissue sarcoma when other treatments have not been successful. Additionally, it is utilized in combination with other medications to manage ovarian cancer that has returned.
This medication is administered as an injection under the supervision of a healthcare provider. The dosage and frequency of the injections will be determined by your doctor based on your specific condition, and it may need to be adjusted over time. It is important to follow your doctor's instructions precisely to avoid serious side effects. It may take some time before you notice the benefits of the treatment, so it is crucial not to discontinue it unless directed by your doctor.
Common side effects of Yondelis Injection include headache, fatigue, vomiting, weakness, and elevated liver enzymes. This medication can also decrease the number of blood cells in your body, making you more susceptible to infections. Regular blood tests are necessary to monitor your blood cells, as well as the health of your heart, liver, and kidneys. It is advisable to refrain from consuming alcohol while undergoing treatment with this medication.
Prior to starting treatment with Yondelis Injection, inform your doctor if you have heart disease, liver or kidney issues, or if you are taking any medications for infections. Since this medication can interact with a wide range of other drugs, it is crucial to disclose all medications you are currently using to your doctor. Yondelis Injection is not recommended during pregnancy or while breastfeeding, and it is vital for both males and females to use effective contraception during treatment to prevent pregnancy.
Benefits
Yondelis Injection offers significant benefits for those suffering from soft tissue sarcoma, a type of cancer that develops in tissues like bone and muscles. This medication works by effectively killing cancer cells and halting their growth, ultimately preventing the further multiplication of these harmful cells. It is crucial to adhere closely to your doctor's instructions when using Yondelis Injection, and it is advisable to communicate any side effects you may experience to your healthcare provider. By being diligent in following your doctor's guidance and monitoring your reactions to the treatment, you can maximize the therapeutic benefits of Yondelis Injection in managing soft tissue sarcoma.
How to use the Yondelis Injection
When using Yondelis Injection, it is important to follow the guidance of your doctor or nurse. This medication should only be administered by a healthcare professional and should not be self-administered. Your healthcare provider will give you the injection, typically into a vein. It is important to receive the correct dosage at the recommended intervals to ensure the medication is effective. Be sure to discuss any questions or concerns you may have with your healthcare team. Following their instructions closely will help you get the most benefit from Yondelis Injection.
Uses of Yondelis Injection
Yondelis Injection is prescribed for the treatment of patients with a type of cancer called soft tissue sarcoma. Soft tissue sarcomas are a group of cancers that affect the soft tissues of the body, such as muscles, fat, nerves, and blood vessels. Yondelis Injection is specifically used in individuals dealing with this form of cancer to help manage the disease and its symptoms. This medication is administered through injection and works to target the cancer cells, helping to slow down the progression of the disease. It is an important treatment option for patients diagnosed with soft tissue sarcoma.
What conditions Yondelis Injection treats?
Yondelis Injection is used to treat certain types of cancers. It is used for advanced soft tissue sarcoma when prior treatments have not worked. Additionally, it is part of a combined therapy for recurring ovarian cancer. This medication is administered through injections by a doctor. The dosage and frequency will vary depending on the condition being treated. It may take time to see benefits, so continue as prescribed. Common side effects include headaches, fatigue, vomiting, and weakness. Regular blood tests are needed to monitor blood cells and organ function. Inform your doctor of any existing conditions or medications.
Should you consult a doctor?
If you are experiencing any of the following symptoms while using Yondelis Injection for your cancer treatment, it is important to seek medical attention promptly. Contact your doctor if you have persistent headaches, ongoing fatigue, frequent vomiting, unexplained weakness, persistent nausea, or notice an increase in liver enzymes. Additionally, if you experience low blood platelets, elevated creatine phosphokinase (CPK) levels in your blood, a decrease in white blood cell count (neutrophils), loss of appetite, or constipation, it is recommended to consult your doctor without delay. Remember that some side effects may not require immediate attention but if they continue or cause concern, it is best to seek medical advice to ensure your well-being during the treatment period.
Side effects of Yondelis Injection
When using Yondelis Injection, you may experience various side effects. These side effects are usually not severe and tend to improve as your body gets used to the medication. Some common side effects include headaches, fatigue, vomiting, weakness, nausea, and constipation. In some cases, you may also notice an increase in liver enzymes, low blood platelets, elevated creatine phosphokinase (CPK) levels in the blood, decreased white blood cell count (neutrophils), and loss of appetite. It's essential to consult your doctor if these side effects persist or if you have concerns about them.
Safety advice

liver
Yondelis Injection needs to be used carefully in patients who have liver disease. It might be necessary to adjust the dose of Yondelis Injection in these cases. Make sure to talk to your doctor about this issue before using the medication.

kidney
Yondelis Injection requires caution in patients with kidney disease. Adjusting the dose may be necessary. Consult your doctor.

alcohol
It is not safe to drink alcohol while using Yondelis Injection.

driving
When using Yondelis Injection, be cautious while driving as it may cause tiredness and weakness, affecting your ability to drive safely.

pregnancy
Information about using Yondelis Injection during pregnancy is not available. It is recommended to speak with your doctor before using this medication.

breastfeeding
It is better to consult your doctor before using Yondelis Injection during breastfeeding.
Consumption warning before consuming Yondelis Injection
Before consuming Yondelis Injection, it is crucial to understand the potential risks and precautions associated with this medication. Yondelis is primarily used in the treatment of certain types of cancers, such as advanced soft tissue sarcoma and recurrent ovarian cancer. It is administered via injection under the supervision of a medical professional.
It is vital to follow your doctor's prescribed dosage and schedule strictly to avoid serious side effects. Common side effects include headache, fatigue, vomiting, weakness, and elevated liver enzymes. Yondelis may also lower blood cell counts, making you more susceptible to infections. Regular blood tests to monitor cell counts, as well as heart, liver, and kidney functions, are essential during treatment.
Before starting Yondelis, inform your doctor about any existing heart, liver, or kidney conditions, as well as any medications you are currently taking. Due to potential drug interactions, it is crucial to disclose all medications to your doctor. Pregnant or breastfeeding individuals should avoid this medication, and both males and females must use effective contraception during treatment to prevent pregnancy. Additionally, alcohol consumption should generally be avoided while on Yondelis.
Additional Information
| Habit Forming | No |
| Chemical Class | Benzazocine Derivative |
| Therapeutic Class | - |
| Action Class | Anticancer-others |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹128300
₹133300
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Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 11-Feb-2025
