Xylocaine NF Cream
By Xylocaine NF
Rx
30gm Cream in a Tube

Composition
Lidocaine(1.5% w/w) + Nifedipine(0.3% w/w)

Manufacturer - Zydus Cadila
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after
September, 2025
About Xylocaine NF Cream
Xylocaine NF Cream is a medicinal combination of Lidocaine and Nifedipine, used for treating anal fissures, which are small tears in the lining of the anus leading to pain, bleeding, and discomfort during bowel movements. This cream helps relieve pain, swelling, itching, and discomfort that accompany anal fissures. When applied, Xylocaine NF Cream works by relaxing the blood vessels around the anus, promoting healing of the fissures.
The active ingredients of Xylocaine NF Cream, Lidocaine (a local anesthetic) and Nifedipine (a calcium channel blocker), work together to alleviate pain and promote healing. Lidocaine blocks pain signals from nerves, reducing pain sensation, while Nifedipine blocks calcium action on blood vessels, aiding in muscle relaxation and improved blood flow in the anal region. By reducing anal canal pressure, this cream helps diminish pain and spasms in the anal area, facilitating the healing process.
To use Xylocaine NF Cream effectively, clean and dry the affected area before application, and avoid contact with eyes, nose, or mouth. It should be applied as directed by a healthcare professional, typically within the rectal area using a provided applicator. Users are advised to wash hands thoroughly before and after application and to avoid reusing the applicator to prevent contamination. Consistent usage at the recommended time each day is essential for optimal results.
While Xylocaine NF Cream is generally well tolerated with minimal side effects, some individuals may experience temporary anal irritation. However, if this irritation persists or worsens, it is crucial to consult a doctor promptly. Additionally, users should seek medical attention if accidental exposure occurs in sensitive areas like eyes, nose, or mouth. It is essential to follow prescribed dosages and not discontinue use abruptly without medical advice to prevent potential worsening of the condition.
Benefits
Xylocaine NF Cream, specifically designed for the treatment of anal fissures, offers several benefits to individuals suffering from this condition. This cream is formulated with Lidocaine and Nifedipine, two potent ingredients that work together to provide relief from pain, irritation, and itching associated with anal fissures.
Lidocaine, a local anaesthetic, acts by temporarily numbing the anal region, thereby reducing discomfort and pain. By blocking nerve impulses and decreasing permeability to sodium ions in the neuronal membrane, Lidocaine effectively lessens depolarization, resulting in the alleviation of rectal discomfort. This mechanism allows individuals to experience a temporary loss of sensation in the affected area, providing much-needed relief.
On the other hand, Nifedipine, another key component of Xylocaine NF Cream, works by relaxing the smooth muscles surrounding the anus. By promoting increased blood flow in the anal area and blocking the action of calcium on the blood vessels, Nifedipine helps in reducing anal canal pressure and relieving pain and spasm. This muscle relaxation effect aids in healing anal fissures faster, as it enhances the overall healing process by reducing pressure in the anal tissues.
Overall, the combined action of Lidocaine and Nifedipine in Xylocaine NF Cream effectively targets the symptoms of anal fissures, offering individuals an efficient way to manage pain, irritation, and itching, and promoting faster healing of the anal fissure. It is important to follow the prescribed dosage and duration as advised by a healthcare professional to maximize the benefits of this cream and achieve optimal relief from anal fissure discomfort.
How to use the Xylocaine NF Cream
To properly use Xylocaine NF Cream, follow these steps recommended by your doctor. This cream is meant for external use only, so do not take it orally. Before applying the cream, make sure to clean and dry the affected area. You can use gentle soap and water to clean the area, then rinse and pat it dry. If provided, use the single-use wipes that come with the cream to further clean the affected area.
Next, fill the medication in the applicator that comes with the cream. Insert the applicator just 1/2 to 1 inch inside the anus area, following the instructions given by your doctor. Make sure to also apply the cream to the anal opening as directed. After each use, discard the applicator and never reuse it. Do not apply the medication with your fingers; always use the provided applicator for hygienic purposes.
If applying the cream to the outside region of the anus, gently rub a small amount of the cream on the affected area. Remember to wash your hands immediately after applying the medication. Avoid contact with the cream in areas such as the nose, ears, eyes, or mouth.
It's important to use Xylocaine NF Cream regularly to experience its full benefits. Follow the dosage and duration of treatment prescribed by your doctor, as they will determine the correct amount based on your age and the severity of your condition. If your symptoms do not improve or worsen after one to two weeks of use, seek medical assistance promptly.
When using the cream rectally, wash your hands before application. For added protection, consider using a finger covering like plastic wrap, cling film, a finger cot, or a disposable glove. Apply the cream to the anal region according to your doctor's instructions. By following these steps as advised, you can effectively use Xylocaine NF Cream for your specific condition.
Uses of Xylocaine NF Cream
Xylocaine NF Cream is commonly used for treating conditions such as anal fissure, which is a tear in the lining of the anus. This cream helps in providing relief from pain and in relaxing muscles during the treatment or examination of various conditions like anal fissure, thrombosed external hemorrhoids, post-hemorrhoidectomy, and anal sphincter hypertonia. It works effectively in managing these conditions by numbing the affected area and reducing discomfort, making medical procedures and recovery more bearable.
What conditions Xylocaine NF Cream treats?
An anal fissure is a small tear in the lining of the anus, causing bleeding and severe pain during bowel movements. It can affect individuals of all ages, particularly young children and infants due to common issues like constipation. Possible causes include chronic constipation, hard stool, diarrhoea, childbirth straining, and inflammatory bowel disease. Symptoms include a crack around the anus, pain during bowel movements, a small lump nearby, and passing bright red stool.
Should you consult a doctor?
It is important to seek medical advice before using Xylocaine NF Cream if you have severe hypotension. Inform your doctor if you have severely injured mucosa or inflammation, as well as if you have diabetes. These conditions may affect the safety and effectiveness of the cream, and the doctor can provide guidance on whether it is suitable for you. If you experience any discomfort, such as severe hypotension or worsening inflammation, stop using the cream and consult your doctor promptly for further evaluation and care.
Side effects of Xylocaine NF Cream
When using Xylocaine NF Cream, you may experience side effects. These can include anal irritation, reactions at the application site such as swelling, itching, and rash. You might also feel a tingling sensation, changes in temperature sensations, or pain and burning sensations. Some users may notice hyperaemia or bleeding. Remember, most of these side effects are usually mild and temporary as your body gets used to the medication. If any of these side effects persist or cause concern, it's essential to consult your doctor for advice.
Safety advice

liver
There is no known interaction or established connection between Xylocaine NF Cream and liver issues. It is important to note that no caution or specific safety advice related to the liver has been identified. It is always recommended to consult with your doctor for proper guidance before using Xylocaine NF Cream.

kidney
No interaction found with kidney issues related to Xylocaine NF Cream. Consult with your doctor for proper guidance before using Xylocaine NF Cream.

alcohol
There is no known interaction between alcohol and Xylocaine NF Cream. It is advisable to consult your doctor if you have any concerns about consuming alcohol while using this cream.

driving
It is safe to drive while using Xylocaine NF Cream as no interactions have been found.

pregnancy
Xylocaine NF Cream may not be safe to use during pregnancy due to potential harmful effects on the developing baby. Limited human studies and animal studies suggest caution. Your doctor will assess benefits and risks before prescribing. Please consult your doctor before use.

breastfeeding
Xylocaine NF Cream is considered safe for use during breastfeeding based on limited human data indicating no significant risk to the baby.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Xylocaine NF Cream
Prior to using Xylocaine NF Cream 30gm, inform your doctor if you have a hypersensitivity to it. Discuss your medical history with your doctor, especially if you have broken skin or an infection in the application area, or if you suffer from heart disease, liver disease, or a kidney disorder. It is important not to exceed the recommended dosage or use this medication more often than prescribed, as it is absorbed through the skin and may lead to severe adverse reactions.
Disease interactions
When using Xylocaine NF Cream 30gm, it is important to consider potential interactions with certain diseases. It is recommended to inform your healthcare provider about any past or current medical conditions you may have. This information can help prevent any adverse effects or complications that may arise due to the interaction between the cream and specific diseases. By communicating openly with your doctor about your medical history, you can ensure safe and effective use of Xylocaine NF Cream.
What happens if you take overdose of Xylocaine NF Cream?
If you or someone has applied an excessive amount of Xylocaine NF Cream, it's important to seek immediate medical help. Overdose symptoms include feeling light-headed, dizzy, experiencing ringing in the ears, lowered blood pressure, changes in heart rate, and more. Consult your doctor or go to the nearest hospital if you suspect an overdose.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | - |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹214.15
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 11-Feb-2025