Votrient 400mg Tablet

By Votrient

Rx

30 Tablet in a Strip

Composition icon

Composition

Pazopanib(400mg)

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd icon

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd

Dr. Annie Besant Road, Mumbai - 400 030

Expires on or after icon

Expires on or after

September, 2025

About Votrient 400mg Tablet

Votrient 400mg Tablet, containing Pazopanib, is categorized as a protein kinase inhibitor used primarily to treat kidney cancer and soft tissue sarcoma. Kidney cancer, or renal cancer, is characterized by healthy kidney cells becoming cancerous and forming tumors through uncontrolled growth. Soft tissue sarcomas, on the other hand, involve cancerous growth in various body tissues like muscles, blood vessels, or connective tissues supporting organs. Votrient 400mg Tablet works by inhibiting abnormal proteins that promote the multiplication of cancer cells, thereby halting their spread effectively.

It is crucial to adhere to the prescribed dosage and schedule when taking Votrient 400mg Tablet, ideally on an empty stomach at the same time daily as determined by your doctor. Continuous adherence to the medication is essential for treatment effectiveness. Potential common side effects may include itching, skin rash, acne, dry skin, vomiting, diarrhea, and loss of appetite, which typically diminish over time and may not necessitate medical intervention. However, persistent side effects should be promptly discussed with your healthcare provider.

Before initiating Votrient 400mg Tablet, inform your doctor about any existing heart, liver, or kidney conditions, previous lung ailments, thyroid issues, bleeding tendencies, stomach problems, or high blood pressure, as well as the use of other medications to prevent potential drug interactions. Notably, the medication is contraindicated during pregnancy, breastfeeding, and in individuals below 18 years due to the risk of serious birth defects. Elderly patients may require dosage adjustments, and alcohol consumption should be avoided to prevent increased dizziness.

Regular monitoring of liver, kidney, and heart functions, along with blood pressure checks, may be recommended before and during Votrient 400mg Tablet treatment to ensure safe usage. If experiencing adverse effects like indigestion, bloating, flatulence, nosebleeds, dry mouth, mouth ulcers, or dizziness, consulting with your doctor for further guidance is advisable to manage symptoms effectively.


Benefits

Votrient 400mg Tablet offers several benefits in the treatment of kidney cancer and soft tissue sarcoma. In kidney cancer, this medication effectively treats the cancer and its associated symptoms like blood in the urine, unexplained low back pain, weight loss, fatigue, and loss of appetite. By halting the growth of cancer cells and preventing their multiplication, Votrient 400mg Tablet helps to impede the progression of cancer to other parts of the body. It is crucial to adhere to your doctor's guidance diligently to achieve optimal recovery.

Moreover, in soft tissue sarcoma, which is a type of cancer developing in tissues like bone and muscles, Votrient 400mg Tablet plays a vital role in killing or halting the growth of cancer cells. This medication also works to prevent the further multiplication of cancer cells. It is essential to closely follow your doctor's instructions while taking Votrient 400mg Tablet and communicate any concerns about potential side effects to your healthcare provider. By following these guidelines, patients can effectively benefit from the therapeutic effects of Votrient 400mg Tablet in managing kidney cancer and soft tissue sarcoma.


How to use the Votrient 400mg Tablet

To use Votrient 400mg Tablet effectively, it is important to follow the dosage and duration recommended by your doctor. The tablet should be swallowed whole with a glass of water. It is essential not to chew, crush, or break the tablet before consuming it. To ensure maximum effectiveness, Votrient 400mg Tablet should be taken on an empty stomach. Remember to consult your healthcare provider for the correct dosage and duration suited to your specific condition. Following these instructions will help you get the most benefit from Votrient 400mg Tablet.


Uses of Votrient 400mg Tablet

Votrient 400mg Tablet is commonly used in the treatment of kidney cancer and soft tissue sarcoma. It is a medication that is prescribed by healthcare professionals to help patients battling these specific types of cancer. Kidney cancer is a serious condition where cancer cells form in the tissues of the kidneys, while soft tissue sarcoma affects the soft tissues of the body such as muscles, tendons, and blood vessels. Votrient 400mg Tablet plays a vital role in targeting and fighting against the cancer cells associated with these diseases, aiding in the treatment of patients who are diagnosed with kidney cancer or soft tissue sarcoma.


What conditions Votrient 400mg Tablet treats?

Votrient 400mg Tablet is used to treat kidney cancer and soft tissue sarcoma. In kidney cancer, it helps with symptoms like blood in urine, low back pain, weight loss, fatigue, and loss of appetite. The medicine stops cancer growth and prevents the spread of cancer cells. For soft tissue sarcoma, which affects tissues like bones and muscles, Votrient 400mg Tablet works by killing cancer cells and preventing their multiplication. It is crucial to adhere to your doctor's instructions for proper recovery. Be aware of potential side effects like diarrhea and high blood pressure, and consult your doctor if needed.


Should you consult a doctor?

Seek medical advice if you experience persistent side effects like diarrhea or high blood pressure. Contact your doctor if you notice symptoms of infection such as fever, flu-like illness, or difficulty breathing. Inform your healthcare provider if you have underlying heart, liver, or kidney issues, or if you are taking other medications. It is crucial to discuss your treatment plan with your doctor to avoid potential interactions. Additionally, seek medical guidance if you are pregnant, breastfeeding, or planning pregnancy, as this medicine may pose risks. Always consult your healthcare team if you have concerns about any side effects or if symptoms persist.


Side effects of Votrient 400mg Tablet

When taking Votrient 400mg Tablet, some individuals may experience certain side effects. These effects are generally mild and often fade as your body gets used to the medication. However, if any of these side effects persist or cause concern, it is advisable to consult your doctor for further guidance and support. Common side effects of Votrient 400mg Tablet may include headaches, nausea, vomiting, musculoskeletal pain (related to bones, muscles, or joints), fatigue, diarrhea, high blood pressure, decreased appetite, weight loss, taste changes, abnormal skin pigmentation, hair discoloration, tumor pain, and breathlessness. It is important to be aware of these potential side effects and seek medical advice if needed.


Safety advice

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liver

When using Votrient 400mg Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require a dosage adjustment when taking Votrient 400mg Tablet, so it is crucial to consult your doctor before use. It is not recommended to use Votrient 400mg Tablet in patients with moderate to severe liver disease. Please take special care and seek medical advice if you have any liver problems.

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kidney

Votrient 400mg Tablet can be used safely by patients with kidney disease. No dosage adjustment is needed.

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alcohol

Consult with your doctor about consuming alcohol along with Votrient 400mg Tablet as it is unknown if it is safe.

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driving

Avoid driving while taking Votrient 400mg Tablet if you experience decreased alertness, vision changes, drowsiness, or dizziness. It's important to prioritize safety and refrain from getting behind the wheel in such instances.

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pregnancy

Votrient 400mg Tablet should not be used during pregnancy due to potential harm to the developing baby. It may be prescribed in life-threatening situations with caution. Always seek advice from a healthcare professional before usage.

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breastfeeding

Votrient 400mg Tablet is not safe to use while breastfeeding as it may harm the baby with potential toxicity.


Consumption warning before consuming Votrient 400mg Tablet

Before consuming Votrient 400mg Tablet, it is crucial to follow important guidelines. Take this protein kinase inhibitor on an empty stomach daily at the same time as prescribed by your doctor. The dosage and frequency will be determined by your doctor based on your condition. Strictly adhere to your doctor's instructions as improper intake can lead to severe side effects. It may take time to observe the benefits, so do not discontinue without your doctor's approval.

Common side effects include diarrhea and high blood pressure. Ensure regular blood pressure checks, stay hydrated to manage diarrhea, and promptly report any signs of infection like fever or breathing difficulties. Inform your doctor about any heart, liver, or kidney issues, current medications, and abstain from using this drug during pregnancy or breastfeeding. Effective contraception is advised for both genders during treatment to prevent pregnancy. Your doctor should be aware of all medications you are taking to avoid interactions.


Related lab tests

For patients taking Votrient 400mg Tablet, it is important to monitor their health with related lab tests. One crucial lab test to consider is the Complete Blood Count (CBC). This test provides information on the different types of cells in the blood, including red blood cells, white blood cells, and platelets. It helps in detecting various conditions such as anemia, infections, and clotting disorders. Additionally, the CBC can give insights into overall health and help healthcare providers assess the effectiveness of the medication.

Other related lab tests that may be relevant for individuals on Votrient 400mg Tablet include:

1. Liver Function Tests: These tests help in evaluating the health of the liver by measuring levels of enzymes and proteins in the blood. Monitoring liver function is important as certain medications can impact liver health.

2. Kidney Function Tests: These tests assess the functioning of the kidneys by measuring levels of creatinine and urea in the blood. It is important to monitor kidney function when taking certain medications to ensure there are no adverse effects on the kidneys.

3. Lipid Profile: This test measures levels of cholesterol and triglycerides in the blood and helps in assessing the risk of heart disease. Monitoring lipid levels is important for individuals on long-term medications.

4. Electrolyte Panel: This test measures levels of important minerals such as sodium, potassium, and calcium in the blood. Imbalances in electrolytes can lead to various health issues, so monitoring electrolyte levels is essential.

Regular monitoring through these related lab tests can help in ensuring the safety and effectiveness of treatment with Votrient 400mg Tablet. It's important to consult with healthcare providers for appropriate testing schedules and interpretation of results.


Additional Information

Habit FormingNo
Chemical ClassAlkyldiarylamines Derivative
Therapeutic Class-
Action ClassTyrosine kinase inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 01-Oct-2024