Valprol -CR 400 Tablet
By Valprol
Rx
15 Tablet CR in a Strip

Composition
Sodium Valproate(266.66mg) + Valproic Acid(116mg)

Manufacturer - Intas Pharmaceuticals Ltd
Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Expires on or after
December, 2025
About Valprol -CR 400 Tablet
Valprol -CR 400 Tablet is a medication that contains a combination of two active ingredients: Sodium valproate and Valproic acid. This medicine is primarily used to treat epilepsy, which is a neurological disorder characterized by recurrent episodes of seizures or fits. Epilepsy occurs due to sudden bursts of electrical impulses in the brain, disrupting the normal brain activity and affecting a person's consciousness, movements, or sensations.
Valprol -CR 400 Tablet works by reducing the excessive and abnormal nerve activity in the brain. It helps control seizures by increasing the levels of a chemical substance called GABA, which blocks nerve transmission and produces a calming effect on the brain. In addition to epilepsy, this medication is also used to manage mood disorders and migraine.
When taking Valprol -CR 400 Tablet, it is essential to follow your doctor's instructions regarding dosage and frequency. The dose may be adjusted gradually until your condition stabilizes. It may take several weeks for the medicine to show its full effect, so it is vital to take it regularly as prescribed. Do not discontinue the medication without consulting your doctor, as it can lead to an increase in seizures or worsening of bipolar disorder symptoms.
Common side effects of Valprol -CR 400 Tablet include nausea, vomiting, loss of appetite, headache, tremors, hair loss, and liver injury. Most side effects tend to diminish over time, but if they persist or become bothersome, inform your doctor. Before starting this medication, disclose any pre-existing kidney or liver issues, meningitis, depression, or suicidal thoughts to your doctor. Also, inform your healthcare provider about all other medications you are using, as some may interact with Valprol -CR 400 Tablet.
It is important to note that pregnant or breastfeeding individuals should use Valprol -CR 400 Tablet only if necessary, under the guidance of a healthcare professional. Regular monitoring through blood tests may be required to assess how you are responding to the medication. Avoid alcohol consumption while on Valprol -CR 400 Tablet, as it can exacerbate certain side effects. Additionally, this medication may lead to weight gain, so maintaining a healthy diet and exercising regularly is recommended.
If you experience any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking Valprol -CR 400 Tablet, promptly inform your doctor. Caution is advised while driving or operating machinery, as this medication can cause drowsiness or dizziness. Special care should be taken when administering Valprol -CR 400 Tablet to children under 3 years old, as there is a higher risk of liver intoxication during the initial months of treatment.
Benefits
Valprol -CR 400 Tablet offers several benefits in the treatment of epilepsy and related conditions. By slowing down the electrical signals in the brain that trigger seizures, this medication helps in managing symptoms like confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety associated with seizures. Importantly, it enables individuals to engage in activities they might have been reluctant to do, such as swimming and driving, thus enhancing their quality of life.
This medication, a combination of Sodium valproate and Valproic acid, is effective in reducing excessive and abnormal nerve activity in the brain, thereby controlling seizures. It is particularly useful for various forms of epilepsy, including petit mal epilepsy characterized by short-term unconsciousness, myoclonic seizures involving sudden muscle contractions, and grand mal epilepsy marked by severe muscle contractions leading to unconsciousness. Moreover, Valprol -CR 400 Tablet can also be beneficial for epilepsy cases that do not adequately respond to other anticonvulsant drugs, offering a treatment option for various types of seizures affecting both specific brain regions and the entire brain.
Although it may take a few weeks for the medication to reach its full effect due to the gradual dose increment, it is essential to continue taking Valprol -CR 400 Tablet as prescribed by the doctor. Even if symptoms improve, stopping the medication abruptly can increase the risk of seizures. Consistent use, as directed by the healthcare provider, is crucial to optimize the benefits of this medication and effectively manage epilepsy symptoms. Remember, missing doses can trigger a seizure, so adhering to the prescribed regimen is essential for the successful management of epilepsy.
How to use the Valprol -CR 400 Tablet
To use Valprol -CR 400 Tablet, follow your doctor's instructions on the dose and duration of the medicine. It is essential to swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. For best results, take the tablet with food or 1 hour before eating. This medication works best when taken regularly as prescribed by your healthcare provider. Remember to not make any changes to the dosage or frequency without consulting your doctor. If you have any questions or concerns about how to use Valprol -CR 400 Tablet, don't hesitate to reach out to your healthcare professional for guidance.
Uses of Valprol -CR 400 Tablet
Valprol -CR 400 Tablet is primarily used to manage epilepsy, mood disorders, and migraines. In epilepsy, it helps control and prevent seizures by stabilizing electrical activity in the brain. For mood disorders, this medication can help stabilize mood swings and manage symptoms of bipolar disorder. Additionally, for migraines, Valprol -CR 400 Tablet can be used to prevent or reduce the frequency and severity of migraine headaches. It is important to follow the prescribed dosage and instructions from a healthcare provider when using this medication for any of these conditions.
What conditions Valprol -CR 400 Tablet treats?
Valprol -CR 400 Tablet is used to treat epilepsy and seizures. These conditions involve abnormal electrical activity in the brain, causing recurrent seizures. Causes may include brain injury, stroke, genetic disorders, and other factors leading to symptoms like mood changes, muscle jerking, confusion, and loss of consciousness. This medication helps manage these conditions by regulating brain activity.
Should you consult a doctor?
If you experience persistent side effects such as nausea, vomiting, weight gain, loss of appetite, gum swelling, headache, sleepiness, tremors, hair loss, or liver injury while taking Valprol -CR 400 Tablet, it is important to consult your doctor. Additionally, seek medical advice if you notice bleeding gums, epigastralgia, diarrhea, memory impairment, decreased sodium level in the blood, anemia, thrombocythemia, or pain during periods. It is crucial to inform your doctor about any unusual changes in mood or behavior, new or worsening depression, or thoughts of self-harm. If you are pregnant or breastfeeding, have kidney or liver issues, meningitis, or are taking other medications, discuss these with your doctor before using this medicine. Regular monitoring and blood tests may be necessary to assess your response to the treatment. If you experience any worrisome symptoms or have concerns about the medication, do not hesitate to seek medical assistance.
Side effects of Valprol -CR 400 Tablet
Valprol -CR 400 Tablet may cause several side effects, although most of them do not typically require medical attention and tend to diminish as your body gets used to the medication. However, if these side effects persist or cause concern, it's important to consult your doctor. Common side effects of Valprol -CR 400 Tablet include nausea, vomiting, weight gain, loss of appetite, gum swelling, headache, sleepiness, tremors, hair loss, and liver injury. In addition, some individuals may experience increased liver enzymes, bleeding gums, epigastralgia, diarrhea, memory impairment, decreased sodium levels in the blood, anemia, thrombocythemia, and pain during menstrual periods. Other potential side effects may include impaired coordination, apathy, irregular periods, and drowsiness. If you experience any of these side effects and are concerned, seek advice from your healthcare provider.
Safety advice

liver
Valprol -CR 400 Tablet should be used with caution in patients with liver disease. It may require dose adjustment, so it's important to consult your doctor before using this medication. It is not recommended for patients with severe liver disease or active liver disease.

kidney
Valprol -CR 400 Tablet is likely safe for patients with kidney disease. Data indicates dose adjustment may not be necessary. Consult your doctor if you have underlying kidney issues.

alcohol
It is not safe to drink alcohol while taking Valprol -CR 400 Tablet.

driving
Valprol -CR 400 Tablet may cause drowsiness, dizziness, and vision changes. Avoid driving if experiencing these effects.

pregnancy
Valprol -CR 400 Tablet is not safe to use during pregnancy due to the risk it poses to the developing baby. In certain life-threatening situations, a doctor may prescribe it if the benefits outweigh the potential risks. Consult your doctor for guidance.

breastfeeding
Valprol -CR 400 Tablet is considered safe to use during breastfeeding. Studies indicate that the drug does not pass into breastmilk in significant amounts, posing no harm to the baby.
Consumption warning before consuming Valprol -CR 400 Tablet
Before consuming Valprol -CR 400 Tablet Tablet, take note of the following important warnings. Do not take this medication if you are allergic to any of its components, have a history of liver problems, porphyria (a blood disorder), or are prone to bleeding. Inform your doctor if you have certain conditions like inflammation, bone marrow damage, or kidney issues. Promptly report to your healthcare provider if you experience symptoms such as weakness, loss of appetite, or prolonged bleeding while taking the tablet. Seek immediate medical attention if you notice any signs of suicidal thoughts. It is crucial not to discontinue the medication without consulting your doctor to prevent seizure aggravation. Avoid taking Encorate Chrono 400 Tablet if you are pregnant, as it may cause birth defects. If you are of childbearing age, use effective contraception during the treatment. Exercise caution if you are breastfeeding and consult your doctor. This medication can cause drowsiness and dizziness, so refrain from driving when not fully alert. Additionally, avoid alcohol consumption to reduce the risk of seizures. Children under 3 years old should be closely monitored when using this medication due to a higher risk of liver issues in the initial treatment phase.
Disease interactions
When taking Valprol -CR 400 Tablet, it is crucial to inform your doctor about certain conditions you may have. These include depression, liver disease, urea cycle disorders, suicidal tendencies, HIV disease, and thrombocytopenia (low platelet levels). It is important to disclose this information to your healthcare provider to avoid any potential drug interactions and to ensure the safety and efficacy of your treatment. By being open about your medical history, your doctor can make informed decisions about your medication regimen to prevent any adverse effects.
What if you forgot to take Valprol -CR 400 Tablet?
If you forget to take your Valprol -CR 400 Tablet dose, try to take it as soon as you remember. But if it’s almost time for your next dose, it's better to skip the missed dose and continue with your usual dosing schedule. Avoid taking a double dose to make up for the missed one. Remember to stay consistent with your medication routine to ensure its effectiveness.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | NEURO CNS |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹221
Inclusive of all taxes
Content verified by

Dr. Mansi Chaudhari
MBBS - General Medicine
Last update on 01-Oct-2024