Valkem-OD 500 Tablet SR
By Valkem
Rx
10 Tablet SR in a Strip

Composition
Divalproex(500mg)

Manufacturer - Alkem Laboratories Ltd
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Expires on or after
August, 2026
About Valkem-OD 500 Tablet SR
Valkem-OD 500 Tablet SR is a medication used in the treatment of epilepsy and migraine prevention, and it can also help manage bipolar disorder. The active ingredient in Valkem-OD 500 Tablet SR is Valproic acid, which works by reducing abnormal nerve activity in the brain to control seizures. It also increases the levels of a chemical called GABA, which helps to calm the nerves in the brain, aiding in the treatment of bipolar disorder. Additionally, Valkem-OD 500 Tablet SR helps in preventing migraine headaches by limiting nerve pain transmission.
It is important to follow your doctor's instructions regarding the dosage and timing of Valkem-OD 500 Tablet SR. Taking the medication regularly and as prescribed is crucial for optimal control of symptoms. It may take a few weeks for the medication to show its full effect, so patience is key. Missing doses can lead to seizure triggers, and abruptly stopping the medication can worsen your condition.
Like any medication, Valkem-OD 500 Tablet SR may cause side effects. Common side effects include headaches, blurred vision, nausea, dizziness, tiredness, and bruising. Most of these side effects are mild and temporary. However, if you experience a skin rash, redness, or any other concerning side effects, it is important to inform your doctor promptly. Long-term use of Valkem-OD 500 Tablet SR may increase the risk of osteoporosis and bone fractures. Rarely, the medication can lead to suicidal thoughts, so it's essential to report any changes in your mood to your healthcare provider.
Before starting Valkem-OD 500 Tablet SR, inform your doctor about any existing health conditions, such as heart problems, kidney or liver disease, depression, or suicidal thoughts. It is also important to disclose all other medications you are taking to prevent potential interactions. Pregnant women should consult their doctor before using Valkem-OD 500 Tablet SR, as it may cause congenital defects. Avoid alcohol consumption while on this medication, as it can worsen side effects and increase the risk of seizures. Regular monitoring through blood tests may be necessary to ensure you are on the correct dose and that the medication is safe for you.
Benefits
Valkem-OD 500 Tablet SR offers multiple benefits in various medical conditions.
In the treatment of epilepsy/seizures, this medication acts as an anticonvulsant, working to reduce the nerve impulses that cause seizures. By controlling the frequency of seizures, Valkem-OD 500 Tablet SR enables individuals to carry out their daily activities with increased confidence. It helps alleviate symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. Importantly, this medicine is not linked to physical or psychological dependence, but it should be taken regularly as prescribed for optimal effectiveness, as missing doses may trigger a seizure.
For individuals managing bipolar disorder, Valkem-OD 500 Tablet SR plays a crucial role in restoring the normal balance of nerve activity in the brain. By stabilizing mood swings, this medication helps prevent extreme changes in mood and reduces feelings of agitation. While it may take several weeks to observe the full benefits, using Valkem-OD 500 Tablet SR consistently over at least six months, or potentially longer, can lead to fewer low mood episodes. It is essential to continue taking the medication as directed by a healthcare provider and prioritize healthy habits such as proper nutrition and exercise to reduce symptoms associated with bipolar disorder.
Additionally, Valkem-OD 500 Tablet SR offers benefits in the prevention of migraines, although the exact mechanism is still being understood. It is believed to modulate abnormal nerve cell activity in the brain or enhance activity in regions associated with migraines. By averting and decreasing the frequency of headaches, this medication helps individuals engage in their daily routines and improve their overall quality of life.
In summary, Valkem-OD 500 Tablet SR provides valuable therapeutic effects in managing epilepsy/seizures, bipolar disorder, and migraine prevention by regulating nerve activity in the brain, stabilizing mood, and reducing headache occurrences. Following the prescribed dosage and treatment regimen is essential for leveraging the full benefits of this medication and enhancing overall well-being.
How to use the Valkem-OD 500 Tablet SR
To use Valkem-OD 500 Tablet SR, follow your doctor's instructions on the dose and duration. Make sure to swallow the tablet whole with water, without chewing, crushing, or breaking it. While you can take this medication with or without food, it is recommended to take it at the same time each day for consistency. If you are using the oral suspension form, remember to shake the bottle well before each use and take the prescribed dose by mouth using the provided measuring cup, dosing syringe, or dropper. Your physician will determine the right dosage and treatment duration based on factors such as your age, body weight, and the specific condition being treated. Always consult your doctor for personalized guidance on how to use Valkem-OD 500 Tablet SR effectively.
Uses of Valkem-OD 500 Tablet SR
Valkem-OD 500 Tablet SR is commonly used for treating epilepsy or seizures, bipolar disorder, and migraines. It is effective in managing mania and bipolar disorder symptoms, as well as in treating complex partial seizures, either alone or in combination with other types of seizures. Additionally, this medication is also used for the prevention of migraines. It helps in controlling the frequency and intensity of these conditions, offering relief to individuals suffering from epilepsy, bipolar disorder, and migraines.
What conditions Valkem-OD 500 Tablet SR treats?
Valkem-OD 500 Tablet SR is used to treat epilepsy. Epilepsy is a nervous system disorder caused by abnormal nerve cell activity in the brain. It leads to imbalanced electrical rhythms in the brain, resulting in recurrent seizures. These seizures can affect an individual's consciousness, movements, or sensations. There are two types of seizures: generalized, involving the entire brain, and partial, involving only a part of the brain. Seizures can cause muscle cramps, spasms, confusion, or unconsciousness. Possible causes include high fever, trauma, genetic disorders, brain injuries, or stroke.
Should you consult a doctor?
It is essential to seek medical attention before taking Valkem-OD 500 Tablet SR if you have certain health conditions. Do not take this medication if you have POLG and its associated disorder, particularly in children under 2 years old, or urea cycle disorders. Before starting Valkem-OD 500 Tablet SR, inform your doctor if you have systemic lupus erythematosus, porphyria, bleeding or other blood disorders, pancreatitis, hyperammonemia, hyperammonemic encephalopathy, or DRESS syndrome. If you experience any symptoms related to these conditions while taking Valkem-OD 500 Tablet SR, promptly consult your healthcare provider for further evaluation and guidance.
Side effects of Valkem-OD 500 Tablet SR
When taking Valkem-OD 500 Tablet SR, some common side effects may occur as your body gets used to the medication. These can include feeling dizzy, sleepy, or experiencing tremors. You may also notice tingling sensations, changes in body temperature, or gastrointestinal disturbances. In some cases, side effects such as anemia, liver injury, or hypersensitivity reactions like deafness or urinary incontinence may occur. Other possible side effects could include weight gain, menstrual pain, and stomach issues like nausea, vomiting, or diarrhea. Additionally, some individuals may experience symptoms such as hair loss, fatigue, or blurry vision while on this medication. It is essential to speak with your doctor if any side effects persist or cause concern. If you encounter severe side effects like bleeding problems, high ammonia levels in the blood, or allergic reactions, it is crucial to contact your physician immediately. Furthermore, if you experience thoughts of harming yourself or any concerning symptoms related to your health, seek medical attention promptly.
Safety advice

liver
Valkem-OD 500 Tablet SR is considered unsafe for individuals with liver disease. It is recommended to avoid using this medication if you have liver issues. Prior consultation with your doctor is advised before taking Valkem-OD 500 Tablet SR.

kidney
Valkem-OD 500 Tablet SR is safe for use in patients with kidney disease, and there is no need for dose adjustment.

alcohol
When taking Valkem-OD 500 Tablet SR, be careful as it can lead to extreme drowsiness when consumed with alcohol.

driving
When taking Valkem-OD 500 Tablet SR, be cautious while driving as it may cause side effects that can impact your driving ability.

pregnancy
Valkem-OD 500 Tablet SR is not safe to use during pregnancy because it poses a risk to the developing baby. Only in life-threatening cases where benefits outweigh risks, a doctor may consider prescribing it. Consult your doctor before use.

breastfeeding
Valkem-OD 500 Tablet SR is considered safe to use while breastfeeding. Research shows that the medication does not transfer into breastmilk in harmful quantities, posing no risk to the baby.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Valkem-OD 500 Tablet SR
Before consuming Valkem-OD 500 Tablet SR, it is crucial to inform your doctor about all your medical conditions, sensitivities, and current medications. It is essential to disclose if you are pregnant, suspect pregnancy, planning to conceive, or breastfeeding. It is advised not to get pregnant during the course of Valkem-OD 500 Tablet SR and notify your doctor promptly if pregnancy occurs. Avoid alcohol intake while on this medication. Refrain from driving or operating machinery while taking Valkem-OD 500 Tablet SR to ensure safety.
Disease interactions
When taking Valkem-OD 500 Tablet SR, it is important to inform your doctor if you have certain medical conditions. Let your doctor know if you have depression, liver disease, urea cycle disorders, suicidal tendencies, HIV disease, hereditary mitochondrial disorders, or thrombocytopenia (low platelets). These conditions can interact with the medication, and your doctor needs to be aware of them to ensure the safety and effectiveness of your treatment.
What if you forgot to take Valkem-OD 500 Tablet SR?
If you forget to take your Valkem-OD 500 Tablet SR, take it when you remember. But if it's almost time for your next dose, just continue with your usual dosing schedule. Do not take double the dose to make up for the missed one.
What happens if you take overdose of Valkem-OD 500 Tablet SR?
In case of overdosing on Valkem-OD 500 Tablet SR, seek immediate medical help from a doctor or the nearest hospital. Overdose symptoms may include feeling excessively drowsy, heart block, and possibly falling into a deep coma. If you suspect an overdose, it is crucial to get prompt medical attention for appropriate treatment and care.
Related lab tests
Related Lab Tests for Valkem-OD 500 Tablet SR may include an Electroencephalogram (EEG) and a Magnetic Resonance Imaging (MRI) test. An EEG is a test that measures electrical activity in the brain through sensors attached to the scalp. This test can help in diagnosing conditions such as seizures, epilepsy, or sleep disorders. On the other hand, an MRI uses powerful magnets and radio waves to create detailed images of the inside of the body, including the brain. It can provide valuable information about any structural abnormalities or conditions that may be affecting the brain. These tests can complement the use of Valkem-OD 500 Tablet SR in diagnosing and monitoring certain neurological conditions.
Additional Information
Habit Forming | No |
Chemical Class | Aliphatic Carboxylic acid Derivatives |
Therapeutic Class | NEURO CNS |
Action Class | Sodium channel modulators (AED) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹217
Inclusive of all taxes
Content verified by

Dr. Gowri Kulkarni
MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)
Last update on 11-Feb-2025