Topirate 25 Tablet

By Topirate

Rx

15 Tablet in a Strip

Composition icon

Composition

Topiramate(25mg)

Manufacturer - Pulse Pharmaceuticals icon

Manufacturer - Pulse Pharmaceuticals

4F10, Ballad Estates, Tarnaka, Hyderabad - 500017, TS, India.

Expires on or after icon

Expires on or after

July, 2025

About Topirate 25 Tablet

Topirate 25 Tablet, also known as topiramate, is a medication prescribed for the treatment of epilepsy (seizures), prevention of migraines, and management of Lennox-Gastaut syndrome – a severe form of epilepsy starting in childhood. Epilepsy is a chronic condition causing recurrent, unprovoked seizures, impacting brain function. Seizures are sudden, uncontrollable brain activities resulting in loss of control. Migraine, on the other hand, manifests as severe headaches with associated symptoms like nausea, vomiting, and sensitivity to light and sound.

Topirate 25 Tablet falls under the category of antiepileptic/anticonvulsant agents, working by restoring neural activity balance and reducing the spread of seizure activity in the brain. This control of brain electrical activity helps manage seizures and alleviate migraine symptoms. The medication is required to be taken on an empty stomach with water, following prescription guidelines strictly. It is available as tablets or capsules for oral consumption, without crushing or breaking. Dosage adjustments may be necessary based on the weight changes in children.

Common side effects of Topirate 25 Tablet may include drowsiness, dizziness, diarrhea, and nausea. Most side effects are mild and temporary and may not require medical intervention. However, if side effects persist or worsen, consult a healthcare provider promptly. A crucial aspect to consider before taking Topirate 25 Tablet is allergic reactions to the medication. Inform the doctor about any known allergies to its components or previous conditions such as glaucoma, metabolic acidosis, or liver disease. Notably, pregnant women or those planning pregnancy should disclose this information due to potential risks of birth defects like cleft lip and palate associated with the medication's use during pregnancy.


Benefits

Topirate 25 Tablet offers a range of benefits across different medical conditions. In epilepsy or seizures, this anticonvulsant medication works by reducing nerve impulses that trigger seizures. This helps in managing the frequency of seizures, allowing individuals to engage in their daily routine with more confidence. Symptoms such as confusion, uncontrolled jerking movements, loss of awareness, and anxiety can be reduced with the use of Topirate 25 Tablet. Importantly, this medication is not linked to physical or psychological dependence, but it is crucial to take it regularly as prescribed to maintain its effectiveness. Missing doses may lead to triggering a seizure, underscoring the importance of consistent use.


Furthermore, Topirate 25 Tablet is also beneficial in the prevention of migraines, although the exact mechanism is not fully understood. It is believed to modulate abnormal nerve cell activity in the brain or enhance activity in specific regions associated with migraines. By helping to prevent and decrease the frequency of headaches, this medication can significantly improve an individual's ability to carry out daily activities and enhance their overall quality of life.


Moreover, for individuals diagnosed with Lennox-Gastaut syndrome (LGS), a severe and rare form of epilepsy usually seen in early childhood, Topirate 25 Tablet plays a vital role in seizure prevention and control. By decreasing the nerve impulses responsible for seizures, this medication helps in managing the diverse types of seizures experienced by children with LGS. Overall, the benefits of Topirate 25 Tablet in epilepsy, migraine prevention, and Lennox-Gastaut syndrome make it an essential treatment option for individuals seeking to improve their seizure control and quality of life.


How to use the Topirate 25 Tablet

When using Topirate 25 Tablet, it is important to follow the guidance provided by your doctor. Take the medication exactly as advised in terms of dosage and duration. Swallow the tablet whole with a glass of water; do not crush, chew, or break it to avoid a bitter taste. While taking Topirate 25 Tablet, it is recommended to drink plenty of fluids. You can take this medicine with or without food, but try to take it at the same time each day for better effectiveness. Your doctor will determine the right dosage and duration based on factors such as your age, body weight, and the specific condition being treated. Follow your physician's instructions carefully to ensure the best results from Topirate 25 Tablet.


Uses of Topirate 25 Tablet

Topirate 25 Tablet is commonly used for the treatment of epilepsy/seizures, prevention of migraine headaches, and Lennox–Gastaut syndrome. It is effective in treating seizures in adults and children who are 6 years of age or older when used alone. Additionally, it can be used to treat seizures in adults and children above 2 years of age when used in combination with other medicines. For adults, Topirate 25 Tablet can also be used to prevent migraine headaches. It is a versatile medication that can be beneficial in managing these conditions effectively.


What conditions Topirate 25 Tablet treats?

Topirate 25 Tablet is a medication used to treat epilepsy, prevent migraines, and manage Lennox-Gastaut syndrome, a severe form of epilepsy starting in early childhood. For epilepsy, it reduces nerve impulses that trigger seizures, aiding in symptom control. In migraine prevention, its effect on abnormal nerve cell activity helps reduce headaches. In Lennox-Gastaut syndrome, it controls various seizure types by decreasing nerve impulses. Regular intake is crucial to effectiveness, while sudden discontinuation may trigger seizures. Possible side effects include nausea, fatigue, and vision problems, necessitating monitoring and doctor consultation if persistent.


Should you consult a doctor?

Seek a doctor before taking Topirate 25 Tablet if you have a history of metabolic acidosis (abnormality in blood and body fluids), eye problems like glaucoma, growth issues, or are following a high-fat ketogenic diet. These conditions may require special monitoring or adjustments when using Topirate 25 Tablet. It's important to inform your doctor about these factors to ensure safe and effective usage of the medication. If you experience any new or worsening symptoms related to these conditions after starting Topirate 25 Tablet, consult your doctor promptly for further evaluation and guidance. Early intervention and proper medical supervision can help in managing any potential risks or complications associated with the use of this medication.


Side effects of Topirate 25 Tablet

Topirate 25 Tablet may cause several side effects, although not everyone experiences them. It is common for these side effects to fade away as your body becomes accustomed to the medication. However, if any of the following side effects persist or if you are concerned about them, it is important to consult your doctor promptly. Some of the common side effects associated with Topirate 25 Tablet include abdominal pain, diarrhea, dizziness, fatigue, fever, loss of appetite, memory impairment, nausea, nervousness, numbness, psychomotor impairment, sleepiness, speech disorder, taste change, upper respiratory tract infection, visual impairment, and weight loss.


In addition to the common side effects, there are more severe reactions that may occur, which require immediate medical attention. These include signs of decreased platelet and white blood cell counts, indicated by easy bleeding, prolonged fevers, and recurring infections. Other serious side effects to watch for include increased liver enzymes, swelling of glands in the neck, armpit, or groin, increased appetite, elevated mood, signs of psychosis, speech problems, restlessness, slowed thinking, involuntary muscle movements, abnormal senses, heart-related issues, signs of pancreas inflammation, gastrointestinal symptoms, abnormal skin reactions, and neurological symptoms.


Taking Topirate 25 Tablet may also lead to less common but serious side effects, such as kidney stones, increased acid levels in the blood, self-harming thoughts, vision problems, glaucoma, high ammonia levels in the blood, and severe skin reactions like Stevens-Johnson syndrome. If you experience new or worsening signs of depression, seizures, mood changes, concentration problems, or other severe symptoms, it is crucial to discontinue the medication and seek immediate medical attention. It's important to always be aware of the potential side effects of any medication and to promptly report any concerning symptoms to your healthcare provider.


Safety advice

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liver

When using Topirate 25 Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment when taking Topirate 25 Tablet. It is strongly advised to seek guidance and consultation from your doctor before starting or adjusting the usage of this medication.

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kidney

Topirate 25 Tablet requires caution in patients with kidney disease. Dosage adjustment may be necessary. Consult your doctor for guidance.

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alcohol

It is not safe to drink alcohol while taking Topirate 25 Tablet.

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driving

Topirate 25 Tablet may reduce alertness, impact vision, or cause drowsiness and dizziness. Avoid driving if these effects occur.

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pregnancy

Topirate 25 Tablet is not recommended for use during pregnancy due to potential risk to the developing baby. However, in life-threatening situations, a doctor may prescribe it if benefits outweigh risks. Consult your doctor for guidance.

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breastfeeding

Topirate 25 Tablet is not recommended during breastfeeding as it may pass into breastmilk and harm the baby. It's best to consult your doctor before using this medication while breastfeeding.


Age above 75(Geriatrics)

Topirate 25 Tablet should be used with caution in elderly patients. Consult your doctor before taking this medicine.


Age below 6 months(Pediatrics)

Topirate 25 Tablet should be used with caution in children (above 2 years up to 16 years of age). It is not recommended for migraine prevention in children. Consult your doctor before taking this medicine.


Consumption warning before consuming Topirate 25 Tablet

Before consuming Topirate 25 Tablet, it is essential to be aware of some important points. This medicine is primarily used to manage epilepsy, prevent migraines, and treat Lennox-Gastaut syndrome. It can be taken with or without food, ideally at the same time each day. In case of a missed dose, take it as soon as you remember, and complete the full course of treatment even if symptoms improve.


Abruptly stopping Topirate 25 Tablet without consulting your doctor may lead to an increase in seizure frequency. Regular monitoring of serum bicarbonate levels may be advised by your healthcare provider during the treatment period. Be cautious of common side effects like nausea, fatigue, diarrhea, and memory impairment. Vision issues such as myopia or glaucoma may also occur, warranting regular eye check-ups before and during treatment.


This medication can cause dizziness and drowsiness, impacting activities like driving. Consult your doctor if side effects persist or become bothersome. It is paramount to follow medical advice closely while taking Topirate 25 Tablet for optimal results and safety.


What if you forgot to take Topirate 25 Tablet?

If you forget to take a dose of Topirate 25 Tablet, try to take it as soon as you remember. But if it's nearly time for your next scheduled dose, just skip the missed one and resume your regular dosing routine. Remember not to take a double dose to make up for the missed one. Keeping a consistent schedule helps maintain the effectiveness of the medication.


What happens if you take overdose of Topirate 25 Tablet?

In case you or someone else takes too much of Topirate 25 Tablet, it is crucial to seek immediate medical assistance. Symptoms of overdose may include feeling drowsy, fatigued, or less attentive, experiencing dizziness caused by low blood pressure, feeling emotionally down or unsettled, having trouble with coordination, speech, or focus, encountering blurred vision, abdominal discomfort, or seizures. Prompt consultation with a doctor or a visit to the nearby hospital is recommended to address any potential overdose concerns effectively.


Related lab tests

When taking Topirate 25 Tablet, it's important to monitor certain lab tests to ensure your health is optimal. These tests are essential for checking various aspects of your body's functioning. The most relevant lab tests to consider include:


1. Complete Blood Count (CBC): This test helps to evaluate your overall health by measuring different components of your blood, such as red blood cells, white blood cells, and platelets.


2. Blood Sugar Level: Monitoring your blood sugar level is crucial, especially if you have diabetes or are at risk of developing it. This test helps to assess how well your body is processing sugar.


3. Electrolyte Panel: This test checks the levels of electrolytes in your body, such as sodium, potassium, and chloride. Proper electrolyte balance is essential for various bodily functions, including nerve and muscle function.


4. Kidney Function Test: This test is vital for assessing the health of your kidneys, which play a crucial role in filtering waste and regulating fluid balance in the body.


By regularly monitoring these lab tests while taking Topirate 25 Tablet, your healthcare provider can ensure that the medication is safe and effective for you. It's important to follow your healthcare provider's recommendations regarding the frequency of these tests to maintain your overall well-being.


Additional Information

Habit FormingNo
Chemical ClassDioxolopyrans Derivative
Therapeutic ClassNEURO CNS
Action ClassSodium channel modulators (AED)

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024