Topep-DSR Capsule PR
By Topep-D
Rx
10 Capsule PR in a Strip

Composition
Domperidone(30mg) + Pantoprazole(40mg)

Manufacturer - N K Ethical Laboratories
gandhi nagar 6th lane, near bit college berhampur ganjam orissa 760002

Expires on or after
October, 2025
About Topep-DSR Capsule PR
Topep-DSR Capsule PR is a prescription medication used to treat conditions such as gastroesophageal reflux disease (acid reflux), dyspepsia (indigestion), and gastritis. This medicine works by reducing the amount of acid present in the stomach, alleviating symptoms like heartburn, stomach pain, and irritation. It also helps in neutralizing stomach acid and facilitating the passage of gas to reduce discomfort. It is recommended to take Topep-DSR Capsule PR as per the dosage and duration advised by the doctor. Your doctor will determine the appropriate dose based on your condition and response to the treatment. Consistency in taking this medicine as directed by your doctor is crucial to prevent symptoms from reoccurring or worsening. Inform your healthcare provider about all medications you are currently taking as some may interact with or be affected by this medicine.
Topep-DSR Capsule PR contains two active ingredients, namely Domperidone and Pantoprazole. Domperidone acts as a prokinetic and anti-nausea agent, aiding in the treatment of indigestion and stomach pain. On the other hand, Pantoprazole functions as a proton pump inhibitor that reduces the production of excess stomach acid by inhibiting the actions of the gastric proton pump enzyme. This combination is widely used for the treatment of peptic ulcers and gastroesophageal reflux disease (GERD). It helps prevent the release of stomach acid and provides relief from conditions like esophagitis and heartburn. Domperidone works by enhancing the movement of food through the digestive system, reducing bloating, fullness, and indigestion. It also hinders the action of the vomiting center in the brain that triggers nausea and vomiting. Pantoprazole effectively reduces stomach acid levels by blocking the enzyme responsible for acid secretion in the stomach lining.
While using Topep-DSR Capsule PR, it is essential to follow your healthcare provider's instructions. Like all medications, this drug may cause side effects, including diarrhea, stomach pain, dry mouth, dizziness, and headache. Not everyone will experience these side effects, and they are usually temporary and resolve with time. If you have any concerns about the side effects, contact your doctor promptly. It is important to avoid alcohol consumption while taking this medicine as it can exacerbate drowsiness. Lifestyle adjustments such as consuming cold milk and avoiding certain foods like hot tea, coffee, spicy food, or chocolate can contribute to better results. Before initiating treatment with Topep-DSR Capsule PR, inform your doctor if you have kidney or liver disease, or if you are pregnant, planning pregnancy, or breastfeeding.
Additionally, it is advised not to use this medication if you are allergic to any of its components. Prolonged use of Pantoprazole may lead to decreased levels of Vitamin B12 and magnesium. Annual testing for Vitamin B12 and magnesium is recommended for individuals using Topep-DSR Capsule PR for an extended period. This medication is contraindicated in individuals with lupus, an inflammatory autoimmune disease. To improve your health outcomes, avoid beverages containing caffeine, spicy or processed foods, carbonated drinks, and acidic foods like citrus fruits and vegetables.
Benefits
Topep-DSR Capsule PR is a beneficial medication that offers relief for various gastrointestinal conditions. In the treatment of Gastroesophageal reflux disease (GERD), a chronic condition characterized by excess stomach acid production, Topep-DSR Capsule PR works effectively by reducing the amount of acid produced in the stomach. This action helps alleviate the pain associated with heartburn and acid reflux, providing much-needed comfort for individuals suffering from these symptoms. To maximize the effectiveness of the medication, it is essential to take it as prescribed by your healthcare provider.
Moreover, Topep-DSR Capsule PR is also useful in addressing symptoms of indigestion (dyspepsia) by promoting better digestive function and reducing gastric acid production. For individuals experiencing gastrointestinal discomfort due to indigestion, this medication can help provide relief and improve overall comfort. Additionally, Topep-DSR Capsule PR proves beneficial in treating gastritis by managing symptoms, reducing gastric acid levels, and enhancing digestive function. Adhering to the prescribed dose and duration recommended by your doctor is crucial for optimal results.
Furthermore, Topep-DSR Capsule PR is instrumental in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions associated with hyperacidity or acid reflux. The combination of Pantoprazole and Domperidone in the capsule works synergistically to prevent the excessive production of stomach acid and alleviate symptoms like nausea and vomiting. By inhibiting the proton pumps' activity and blocking messages in the brain related to nausea and vomiting, Topep-DSR Capsule PR offers comprehensive relief for individuals dealing with these discomforting symptoms.
In conclusion, Topep-DSR Capsule PR provides a range of benefits for individuals suffering from gastrointestinal issues such as GERD, indigestion, and gastritis. With its proven efficacy in reducing gastric acid production, managing symptoms, and improving digestive function, this medication offers a valuable solution for those seeking relief from discomfort and pain associated with stomach-related conditions. It is important to follow the prescribed guidelines and recommendations for the best outcomes when using Topep-DSR Capsule PR.
How to use the Topep-DSR Capsule PR
To use Topep-DSR Capsule PR, it is important to follow the instructions provided by your doctor or as indicated on the label. It is recommended to take this medication on an empty stomach. Swallow the capsule whole with a glass of water; do not crush, break, or chew it. The ideal time to take Topep-DSR Capsule PR is 15-30 minutes before meals, as directed by your physician.
Your doctor will determine the appropriate dosage and duration of treatment based on factors such as your age, body weight, and the specific condition being treated. It is crucial not to discontinue taking Topep-DSR Capsule PR unless advised by your doctor.
Remember, always follow your healthcare provider’s guidance on how to use Topep-DSR Capsule PR for the best results and to ensure your safety.
Uses of Topep-DSR Capsule PR
Topep-DSR Capsule PR is commonly used for treating conditions related to the stomach and digestive system. It is effective in managing Gastroesophageal reflux disease (Acid reflux) by reducing the production of stomach acid. This medication is also beneficial in addressing Indigestion, which includes symptoms like burping and bloating, providing relief and promoting better digestion. Additionally, Topep-DSR Capsule PR is used to treat Gastritis, a condition characterized by inflammation of the stomach lining. It is also prescribed for Peptic ulcer, a sore in the lining of the stomach, duodenum, or esophagus, helping to alleviate associated symptoms such as nausea, vomiting, acidity, and heartburn. Overall, Topep-DSR Capsule PR is an essential medication for managing various gastrointestinal issues effectively.
What conditions Topep-DSR Capsule PR treats?
The stomach is usually protected by a layer of mucous from its acid. But excessive acid can lead to GERD, peptic ulcers, and Zollinger Ellison syndrome. GERD happens when stomach acid flows back into the food pipe, causing heartburn. Peptic ulcers are sores that develop in the stomach or duodenum. Zollinger Ellison syndrome is rare and involves a gastrin-secreting tumor causing excessive acid and ulcers.
Should you consult a doctor?
Seek medical attention if you experience bloody stools, gut bleeding, intestinal blockage or tear, severe fluid or electrolyte imbalances, or have a prolactinoma, low potassium or magnesium levels. Before using Topep-DSR Capsule PR, consult your doctor if you have osteoporosis, vitamin B12 deficiency symptoms (like sore tongue, mouth ulcers, pale skin, depression), or are planning to test Chromogranin A levels.
Side effects of Topep-DSR Capsule PR
When taking Topep-DSR Capsule PR, you may experience some side effects that usually do not require immediate medical attention. The most common side effects include diarrhea, stomach pain, flatulence, dryness in the mouth, dizziness, and headaches. Additionally, you may also notice symptoms such as nausea, abdominal pain, vomiting, arthralgia (joint pain), low sex drive, anxiety, sleeplessness, breast enlargement in both men and women, and feeling weak. There is also a risk of experiencing fragile bones, risk of bone fracture, benign polyps in the stomach, and dry mouth.
It is essential to consult your doctor if any of these side effects persist or if you are concerned about them. It is recommended to stop taking Topep-DSR Capsule PR and seek immediate medical attention if you encounter severe allergic reactions like skin rash, itching, swelling of lips, face, or body, difficulty in breathing or swallowing, signs of liver problems such as yellowing of the skin and eyes, dark urine, tiredness, severe skin reactions like redness, blistering, peeling of skin, or bleeding in various body parts along with fever, signs of kidney problems like lower back pain, painful urination, signs of low magnesium levels in the blood such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat, skin rashes on sun-exposed areas, sudden weight loss, looking pale and weak (anemia), signs of bleeding in the gut like bloody vomits or stools, chest pain, severe, persistent diarrhea, fast or irregular heartbeat, difficulty in breathing, feeling faint, fits, uncontrollable body movements including eyes and tongue, twisted neck, and abnormal body posture.
Safety advice

liver
Topep-DSR Capsule PR is considered safe for individuals with liver disease based on the available information. It is indicated that adjusting the dose of Topep-DSR Capsule PR may not be necessary for patients with liver issues. It is advisable to seek advice from your healthcare provider before using this medication, especially if you have liver concerns.

kidney
Topep-DSR Capsule PR requires caution in patients with kidney disease. Dosage adjustment may be necessary. Consult your doctor for guidance.

alcohol
Caution is advised when consuming alcohol with Topep-DSR Capsule PR. It is important to consult your doctor.

driving
When taking Topep-DSR Capsule PR, watch out for decreased alertness, vision changes, sleepiness, or dizziness. Avoid driving if these effects happen.

pregnancy
Topep-DSR Capsule PR could be risky during pregnancy. Limited human studies and animal research suggest potential harm to the developing baby. Your doctor will assess the risks and benefits before recommending its use. Kindly consult your healthcare provider.

breastfeeding
During breastfeeding, use Topep-DSR Capsule PR cautiously. It is advisable to pause breastfeeding until the mother's treatment is done and the drug is eliminated from her body.
Age above 75(Geriatrics)
Topep-DSR Capsule PR should be used with caution in elderly patients (aged 65 years and above). Therefore, consult your doctor before taking it.
Age below 6 months(Pediatrics)
Topep-DSR Capsule PR is not recommended for use in children and adolescents (aged below 18 years). However, consult your doctor before taking it.
Consumption warning before consuming Topep-DSR Capsule PR
Before taking Topep-DSR Capsule PR, it is crucial to note certain precautions. Do not consume this medication if you have allergies to Topep-DSR Capsule PR or proton pump inhibitors, gastric cancer, liver issues, low magnesium levels leading to osteoporosis, low vitamin B12 levels, if you are pregnant, planning pregnancy, or breastfeeding. Topep-DSR Capsule PR may interact with various medications like warfarin, ketoconazole, atazanavir, nelfinavir, iron supplements, ampicillin, and methotrexate. Inform your doctor if you are on any of these medications. Prolonged use may lead to lupus erythematosus, Vitamin B12, and magnesium deficiencies. It can also mask symptoms of gastric cancer. Therefore, if you experience severe stomach pain or gastric bleeding, prompt medical consultation is advised.
Disease interactions
When considering the use of Topep-DSR Capsule PR, it is important to be cautious in patients with specific conditions. This medication should not be administered to individuals with C. difficile induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), or low magnesium (hypomagnesemia). Patients with these conditions may experience worsened symptoms or adverse reactions when taking Topep-DSR Capsule PR, so it is crucial to consult with a healthcare provider before starting this medication if any of these conditions are present.
What if you forgot to take Topep-DSR Capsule PR?
If a dose of Topep-DSR Capsule PR is missed, it is important to take it as soon as you remember. However, if it is close to the time for your next scheduled dose, it is advised to skip the missed dose and continue with your regular dosing schedule. It is crucial not to double the dose to make up for the missed one. Following these instructions helps maintain the effectiveness and safety of the medication regimen.
What happens if you take overdose of Topep-DSR Capsule PR?
In the case of an overdose of Topep-DSR Capsule PR, it is essential to seek immediate medical assistance. If you or someone else has taken more than the prescribed amount, contacting a doctor or visiting a hospital is crucial. Symptoms of an overdose may manifest as sleepiness, confusion, involuntary body movements (such as eye and tongue twitching), a twisted neck, and unusual body posture. If any of these signs are noticed, prompt medical attention is necessary to address the situation effectively.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | GASTRO INTESTINAL |
Action Class | - |
FAQs
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Content verified by

Dr. Gowri Kulkarni
MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)
Last update on 18-Nov-2024