Tolvarise 15mg Tablet
By Tolvarise
Rx
4 Tablet in a Strip

Composition
Tolvaptan(15mg)

Manufacturer - Tas Med India Pvt Ltd
Plot No. 45, N.T.M., Sector -26, Chandigarh

Expires on or after
November, 2025
About Tolvarise 15mg Tablet
Tolvarise 15mg Tablet, part of the group of medicines known as vasopressin V2 receptor antagonists, is primarily used to address hyponatremia, characterized by low levels of sodium in individuals with heart failure, liver disease, and hormonal imbalances like Syndrome of Inappropriate Antidiuretic Hormone (SIADH). This medication can also be beneficial for treating autosomal dominant polycystic kidney disease (ADPKD). The active ingredient in Tolvarise 15mg Tablet is 'tolvaptan' which acts by obstructing the effect of vasopressin, leading to reduced water reabsorption, increased excretion of free water (aquaresis), and a rise in serum sodium concentrations. It's important to adhere to your doctor's prescription regarding the duration of Tolvarise 15mg Tablet usage according to your medical condition. Common side effects may include dizziness, headaches, dry mouth, fatigue, diarrhea, thirst, and an increased urge to urinate. In case of persistent side effects, it is advisable to consult your healthcare provider.
If you are pregnant, it is cautioned not to take Tolvarise 15mg Tablet as it may pose risks of harm to the fetus. Consulting your doctor is vital before using this medication while breastfeeding. Tolvarise 15mg Tablet is not recommended for individuals under 18 years of age as its safety and effectiveness have not been established in this age group. Caution is advised while driving as Tolvarise 15mg Tablet may cause dizziness and it is advisable to avoid alcohol consumption as it can exacerbate dizziness. Inform your healthcare provider about all the medications you are currently taking and share details of your health condition to mitigate any potential adverse effects.
TOLVARISE 15 TABLET, containing Tolvaptan, falls under the category of Vasopressin antagonists and is chiefly utilized to combat low serum sodium levels in adults afflicted with Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH), a condition involving excessive water retention by the kidneys. Symptoms of SIADH may encompass nausea, vomiting, headache, confusion, weakness, muscle weakness, irritability, mental confusion, and tremors. Patients with kidney issues are advised against using this medication, and those with conditions such as diabetes, heart disease, liver problems, and autosomal dominant polycystic kidney disease (ADPKD) should exercise caution while using Tolvarise 15 Tablet. Pregnant or breastfeeding individuals should seek advice from their healthcare provider prior to initiating treatment. Moreover, children and adolescents under 18 should refrain from using TOLVARISE 15 TABLET. Common side effects of this medication include thirst, dehydration, nausea, headache, and diarrhea. It is recommended to consult a healthcare professional if these side effects worsen.
Benefits
Tolvarise 15mg Tablet provides a range of benefits for individuals suffering from low levels of sodium in the blood. This condition, known as hyponatremia, can be caused by various factors like excess body fluids, heart disease, and kidney issues, leading to symptoms like nausea, headache, and confusion that may require hospitalization. Tolvarise 15mg Tablet helps by eliminating excess fluids from the body and retaining sodium in the blood, effectively restoring normal sodium levels. By doing so, this medication helps prevent complications such as memory loss associated with low sodium levels. Additionally, Tolvarise 15mg Tablet is also beneficial in treating conditions like Syndrome of Inappropriate Antidiuretic Hormone (SIADH), heart failure, liver disease, and autosomal dominant polycystic kidney disease (ADPKD). By blocking the effect of vasopressin, a hormone involved in cyst formation, Tolvarise 15mg Tablet slows down the progression of cysts in ADPKD patients, reducing symptoms and improving kidney function. Overall, Tolvarise 15mg Tablet's ability to increase free water clearance, decrease urine osmolality, and raise serum sodium concentrations makes it an effective treatment option for individuals with low sodium levels and related conditions.
How to use the Tolvarise 15mg Tablet
To use Tolvarise 15mg Tablet, follow the instructions provided by your doctor carefully. Swallow the tablet whole with a glass of water. Avoid chewing, crushing, or breaking the tablet before consumption. It is recommended to take Tolvarise 15mg Tablet at a consistent time daily, although it can be taken with or without food as per your preference. Remember to adhere to the dosage and duration prescribed by your physician, as they will determine the appropriate amount based on factors such as your age, weight, and medical condition. Consulting your doctor before starting or altering the dosage is crucial for optimal results.
Uses of Tolvarise 15mg Tablet
Tolvarise 15mg Tablet is primarily used for treating low levels of sodium in the blood, a condition known as hyponatremia. It is also beneficial for individuals with autosomal dominant polycystic kidney disease (ADPKD). Specifically, this medication is effective in raising low serum sodium levels in adults diagnosed with the "syndrome of inappropriate antidiuretic hormone secretion" (SIADH). By addressing these conditions, Tolvarise 15mg Tablet plays a crucial role in restoring proper sodium levels and improving overall health.
What conditions Tolvarise 15mg Tablet treats?
Tolvarise 15mg Tablet can be beneficial for individuals experiencing specific health conditions. Hyponatremia, which is characterized by low sodium levels in the blood, can cause symptoms such as weakness, tiredness, nausea, and muscle spasms. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited disorder where non-cancerous cysts develop in the kidneys, potentially resulting in high blood pressure and abdominal or back pain. Tolvarise 15mg Tablet may provide support for individuals managing these conditions by addressing relevant symptoms and promoting overall health.
Should you consult a doctor?
It is important to seek a doctor before taking Tolvarise 15mg Tablet if you have specific health conditions. This includes hypernatremia, a condition characterized by high salt levels in the blood, as well as any condition related to low blood volume. If you experience an inability to recognize when you are thirsty, it is advisable to consult your doctor before using this medication. Additionally, individuals who struggle to drink enough water or are on a fluid-restricted diet, have urination difficulties, an enlarged prostate, or diabetes should inform their doctor before starting Tolvarise 15mg Tablet. Seeking medical advice before taking the medication can help ensure your safety and the effectiveness of the treatment.
Side effects of Tolvarise 15mg Tablet
When taking Tolvarise 15mg Tablet, you may experience some side effects. Most side effects are mild and temporary, typically fading as your body gets used to the medication. However, if these side effects persist or if you feel concerned, it's important to consult your doctor. Some common side effects include a frequent urge to urinate, especially during the night, dryness in the mouth, increased thirst, constipation, nausea, dizziness, headache, fatigue, weakness, and diarrhea. Other potential side effects may include increased levels of creatinine and potassium in the blood, altered taste sensation, signs of kidney problems such as decreased urinary output and fatigue, signs of high sodium levels like restlessness and confusion, excessive thirst, dehydration, signs of high potassium levels such as shortness of breath and chest pain, signs of high creatinine like swelling and high blood pressure, and signs of high uric acid such as joint pain and stiffness. Additionally, some individuals may experience changes in blood sugar levels, decreased appetite, fainting, low blood pressure when standing up, dry mouth, constipation, diarrhea, or itching. It is important to be aware of these potential side effects and to seek medical advice if you experience difficulty in urination, allergic reactions such as swelling, itching, rash, or breathing difficulties, or symptoms of liver issues like abdominal pain, dark urine, and yellowing of the skin or eyes. If you encounter any of these severe side effects, stop taking the medication immediately and contact your doctor.
Safety advice

liver
When it comes to liver disease, it is important to use Tolvarise 15mg Tablet with caution. Patients with liver issues may require a dose adjustment when taking this medication. It is highly advised to consult your doctor before using Tolvarise 15mg Tablet, especially if you have any liver conditions. Patients with severe liver disease are not recommended to use this medication without proper medical supervision. Always seek guidance from your healthcare provider to ensure the safe use of Tolvarise 15mg Tablet.

kidney
Tolvarise 15mg Tablet is safe for use in patients with kidney disease. No dose adjustment is needed. However, it is not recommended for those with severe kidney disease.

alcohol
When taking Tolvarise 15mg Tablet, caution is recommended when drinking alcohol. It is important to consult your doctor about the interaction between alcohol and the medication.

driving
When taking Tolvarise 15mg Tablet, be cautious while driving as it can reduce alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these symptoms.

pregnancy
Tolvarise 15mg Tablet is considered unsafe during pregnancy. Animal studies have shown harmful effects on the developing baby. Your doctor will assess the benefits and risks before prescribing. Please consult your doctor before using.

breastfeeding
Tolvarise 15mg Tablet may be unsafe while breastfeeding. Limited data suggests it could pass into breastmilk and harm the baby.
Age above 75(Geriatrics)
Tolvarise 15mg Tablet is used with caution in patients above 65 years of age. Consult your doctor before taking Tolvarise 15mg Tablet.
Age below 6 months(Pediatrics)
Tolvarise 15mg Tablet is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking Tolvarise 15mg Tablet.
Consumption warning before consuming Tolvarise 15mg Tablet
Before consuming Tolvarise 15mg Tablet, it's crucial to consider certain factors. Firstly, refrain from taking this medication if you have any allergies to its components or if you experience raised liver enzymes, very low blood volume, lack of urine production, or difficulty sensing thirst. Notify your healthcare provider if you have liver problems, urinary issues, diabetes, high uric acid levels, advanced kidney disease, or need to limit fluid intake for medical reasons. Avoid using Tolvarise 15mg Tablet during pregnancy as it may harm the fetus, and consult your doctor if you are breastfeeding. This medication is not suitable for individuals under 18 years old due to limited information on its effectiveness and safety in this age group. Be cautious of potential dizziness from Tolvarise 15mg Tablet and drive carefully. It is advised to avoid alcohol consumption as it can intensify dizziness.
What if you forgot to take Tolvarise 15mg Tablet?
If you happen to miss a dose of Tolvarise 15mg Tablet, don't worry. Simply take the missed dose as soon as you remember it. Just make sure not to take a double dose if it's almost time for your next scheduled dose. If that's the case, it's better to skip the missed dose and continue with your usual dosing schedule. By following these instructions, you can ensure you're taking the medication safely and effectively as prescribed.
What happens if you take overdose of Tolvarise 15mg Tablet?
In the case of an overdose of Tolvarise 15mg Tablet, it is crucial to seek immediate medical assistance from a doctor or visit the nearest hospital. An overdose can lead to symptoms such as an increase in serum sodium concentration, excessive urination (polyuria), feeling excessively thirsty, and dehydration or a decrease in blood volume (hypovolemia) due to a significant loss of fluids. If you suspect an overdose of Tolvarise 15mg Tablet, do not hesitate to seek prompt medical attention to address the situation effectively and ensure your well-being.
Additional Information
Habit Forming | No |
Chemical Class | Benzazepine Derivative |
Therapeutic Class | - |
Action Class | Vasopressin antagonist |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹544.5
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024