Tolsama 15 Tablet

By Tolsama

Rx

4 Tablet in a Strip

Composition icon

Composition

Tolvaptan(15mg)

Manufacturer - MSN Laboratories icon

Manufacturer - MSN Laboratories

MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, INDIA

Expires on or after icon

Expires on or after

June, 2028

About Tolsama 15 Tablet

Tolsama 15 Tablet is a medication used to treat low levels of sodium in the blood, which can occur due to conditions like heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone (SIADH). It is a vasopressin V2 receptor antagonist that works by blocking the effect of vasopressin, leading to decreased water reabsorption and increased excretion of free water. This results in an increase in serum sodium concentrations without affecting the excretion of sodium or potassium ions.

It is important to take Tolsama 15 Tablet exactly as prescribed by your doctor. Your doctor will determine the appropriate dosage and frequency for you. Consistent and regular use of this medication is crucial to gain maximum benefits. Even if you start feeling better, do not stop taking the medication without consulting your doctor first.

While using Tolsama 15 Tablet, you may experience common side effects such as increased thirst, frequent urge to urinate, dryness in the mouth, nausea, and constipation. If these side effects persist or worsen over time, inform your doctor promptly. Prior to using this medicine, discuss any existing kidney or liver problems with your doctor. Regular monitoring of your blood sodium levels will be conducted by your healthcare provider while you are on this medication.

It is advisable not to take Tolsama 15 Tablet if you are pregnant due to potential fetal harm. Consult with your doctor before using this medication if you are breastfeeding. Additionally, Tolsama 15 Tablet is not recommended for individuals below 18 years of age until the safety and efficacy profile for this age group is established. Exercise caution while driving as Tolsama 15 Tablet may cause dizziness. Avoid alcohol consumption as it could exacerbate dizziness. Inform your doctor about all medications you are currently taking and disclose your health status to prevent any adverse reactions.


Benefits

Tolsama 15 Tablet provides a range of benefits for individuals suffering from low levels of sodium in the blood. This condition, known as hyponatremia, can be caused by various factors like excess body fluids, heart disease, and kidney issues, leading to symptoms like nausea, headache, and confusion that may require hospitalization. Tolsama 15 Tablet helps by eliminating excess fluids from the body and retaining sodium in the blood, effectively restoring normal sodium levels. By doing so, this medication helps prevent complications such as memory loss associated with low sodium levels. Additionally, Tolsama 15 Tablet is also beneficial in treating conditions like Syndrome of Inappropriate Antidiuretic Hormone (SIADH), heart failure, liver disease, and autosomal dominant polycystic kidney disease (ADPKD). By blocking the effect of vasopressin, a hormone involved in cyst formation, Tolsama 15 Tablet slows down the progression of cysts in ADPKD patients, reducing symptoms and improving kidney function. Overall, Tolsama 15 Tablet's ability to increase free water clearance, decrease urine osmolality, and raise serum sodium concentrations makes it an effective treatment option for individuals with low sodium levels and related conditions.


How to use the Tolsama 15 Tablet

To use Tolsama 15 Tablet, follow the instructions provided by your doctor carefully. Swallow the tablet whole with a glass of water. Avoid chewing, crushing, or breaking the tablet before consumption. It is recommended to take Tolsama 15 Tablet at a consistent time daily, although it can be taken with or without food as per your preference. Remember to adhere to the dosage and duration prescribed by your physician, as they will determine the appropriate amount based on factors such as your age, weight, and medical condition. Consulting your doctor before starting or altering the dosage is crucial for optimal results.


Uses of Tolsama 15 Tablet

Tolsama 15 Tablet is primarily used for treating low levels of sodium in the blood, a condition known as hyponatremia. It is also beneficial for individuals with autosomal dominant polycystic kidney disease (ADPKD). Specifically, this medication is effective in raising low serum sodium levels in adults diagnosed with the "syndrome of inappropriate antidiuretic hormone secretion" (SIADH). By addressing these conditions, Tolsama 15 Tablet plays a crucial role in restoring proper sodium levels and improving overall health.


What conditions Tolsama 15 Tablet treats?

Tolsama 15 Tablet can be beneficial for individuals experiencing specific health conditions. Hyponatremia, which is characterized by low sodium levels in the blood, can cause symptoms such as weakness, tiredness, nausea, and muscle spasms. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited disorder where non-cancerous cysts develop in the kidneys, potentially resulting in high blood pressure and abdominal or back pain. Tolsama 15 Tablet may provide support for individuals managing these conditions by addressing relevant symptoms and promoting overall health.


Should you consult a doctor?

It is important to seek a doctor before taking Tolsama 15 Tablet if you have specific health conditions. This includes hypernatremia, a condition characterized by high salt levels in the blood, as well as any condition related to low blood volume. If you experience an inability to recognize when you are thirsty, it is advisable to consult your doctor before using this medication. Additionally, individuals who struggle to drink enough water or are on a fluid-restricted diet, have urination difficulties, an enlarged prostate, or diabetes should inform their doctor before starting Tolsama 15 Tablet. Seeking medical advice before taking the medication can help ensure your safety and the effectiveness of the treatment.


Side effects of Tolsama 15 Tablet

When taking Tolsama 15 Tablet, you may experience some side effects. Most side effects are mild and temporary, typically fading as your body gets used to the medication. However, if these side effects persist or if you feel concerned, it's important to consult your doctor. Some common side effects include a frequent urge to urinate, especially during the night, dryness in the mouth, increased thirst, constipation, nausea, dizziness, headache, fatigue, weakness, and diarrhea. Other potential side effects may include increased levels of creatinine and potassium in the blood, altered taste sensation, signs of kidney problems such as decreased urinary output and fatigue, signs of high sodium levels like restlessness and confusion, excessive thirst, dehydration, signs of high potassium levels such as shortness of breath and chest pain, signs of high creatinine like swelling and high blood pressure, and signs of high uric acid such as joint pain and stiffness. Additionally, some individuals may experience changes in blood sugar levels, decreased appetite, fainting, low blood pressure when standing up, dry mouth, constipation, diarrhea, or itching. It is important to be aware of these potential side effects and to seek medical advice if you experience difficulty in urination, allergic reactions such as swelling, itching, rash, or breathing difficulties, or symptoms of liver issues like abdominal pain, dark urine, and yellowing of the skin or eyes. If you encounter any of these severe side effects, stop taking the medication immediately and contact your doctor.


Safety advice

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liver

When it comes to liver disease, it is important to use Tolsama 15 Tablet with caution. Patients with liver issues may require a dose adjustment when taking this medication. It is highly advised to consult your doctor before using Tolsama 15 Tablet, especially if you have any liver conditions. Patients with severe liver disease are not recommended to use this medication without proper medical supervision. Always seek guidance from your healthcare provider to ensure the safe use of Tolsama 15 Tablet.

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kidney

Tolsama 15 Tablet is safe for use in patients with kidney disease. No dose adjustment is needed. However, it is not recommended for those with severe kidney disease.

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alcohol

When taking Tolsama 15 Tablet, caution is recommended when drinking alcohol. It is important to consult your doctor about the interaction between alcohol and the medication.

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driving

When taking Tolsama 15 Tablet, be cautious while driving as it can reduce alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these symptoms.

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pregnancy

Tolsama 15 Tablet is considered unsafe during pregnancy. Animal studies have shown harmful effects on the developing baby. Your doctor will assess the benefits and risks before prescribing. Please consult your doctor before using.

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breastfeeding

Tolsama 15 Tablet may be unsafe while breastfeeding. Limited data suggests it could pass into breastmilk and harm the baby.


Age above 75(Geriatrics)

Tolsama 15 Tablet is used with caution in patients above 65 years of age. Consult your doctor before taking Tolsama 15 Tablet.


Age below 6 months(Pediatrics)

Tolsama 15 Tablet is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking Tolsama 15 Tablet.


Consumption warning before consuming Tolsama 15 Tablet

Before consuming Tolsama 15 Tablet, it's crucial to consider certain factors. Firstly, refrain from taking this medication if you have any allergies to its components or if you experience raised liver enzymes, very low blood volume, lack of urine production, or difficulty sensing thirst. Notify your healthcare provider if you have liver problems, urinary issues, diabetes, high uric acid levels, advanced kidney disease, or need to limit fluid intake for medical reasons. Avoid using Tolsama 15 Tablet during pregnancy as it may harm the fetus, and consult your doctor if you are breastfeeding. This medication is not suitable for individuals under 18 years old due to limited information on its effectiveness and safety in this age group. Be cautious of potential dizziness from Tolsama 15 Tablet and drive carefully. It is advised to avoid alcohol consumption as it can intensify dizziness.


What if you forgot to take Tolsama 15 Tablet?

If you happen to miss a dose of Tolsama 15 Tablet, don't worry. Simply take the missed dose as soon as you remember it. Just make sure not to take a double dose if it's almost time for your next scheduled dose. If that's the case, it's better to skip the missed dose and continue with your usual dosing schedule. By following these instructions, you can ensure you're taking the medication safely and effectively as prescribed.


What happens if you take overdose of Tolsama 15 Tablet?

In the case of an overdose of Tolsama 15 Tablet, it is crucial to seek immediate medical assistance from a doctor or visit the nearest hospital. An overdose can lead to symptoms such as an increase in serum sodium concentration, excessive urination (polyuria), feeling excessively thirsty, and dehydration or a decrease in blood volume (hypovolemia) due to a significant loss of fluids. If you suspect an overdose of Tolsama 15 Tablet, do not hesitate to seek prompt medical attention to address the situation effectively and ensure your well-being.


Additional Information

Habit FormingNo
Chemical ClassBenzazepine Derivative
Therapeutic Class-
Action ClassVasopressin antagonist

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024