Tofajak XR Tablet
By Tofajak
Rx
10 Tablet XR in a Strip

Composition
Tofacitinib(11mg)

Manufacturer - Cipla Ltd
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Expires on or after
July, 2026
About Tofajak XR Tablet
Tofajak XR Tablet is a medication used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. These conditions cause joint pain, swelling, and inflammation, leading to discomfort and potential joint damage. Tofajak XR Tablet contains the active ingredient Tofacitinib, a Janus kinase inhibitor that works by reducing inflammation and alleviating symptoms associated with these autoimmune diseases.
This medication can be taken alone or in combination with other drugs and is typically administered once daily. It is important to follow your doctor's instructions regarding dosage and timing of intake to ensure optimal effectiveness. Do not discontinue the medication without consulting your doctor as this may worsen your condition.
Common side effects of Tofajak XR Tablet include upper respiratory tract infections, headaches, diarrhea, and nasopharyngitis. While most side effects are mild and temporary, there are rare but serious effects such as blood clots and tears in the stomach or intestine walls that require immediate medical attention. If you experience persistent or severe side effects, speak to your healthcare provider.
Before starting treatment with Tofajak XR Tablet, your doctor may recommend blood tests and advise against its use if you have an active infection. It is crucial to inform your doctor about medical history, especially if you have conditions such as tuberculosis, shingles, kidney or liver disease, or a history of blood clots. Due to the potential risk of infections, precautions should be taken to avoid contact with individuals who are ill, particularly with contagious illnesses like chickenpox or the flu.
This medication is not suitable for individuals under 18 years old, pregnant women, or nursing mothers unless the potential benefits outweigh the risks. Regular monitoring by your doctor is essential to ensure the safety and effectiveness of Tofajak XR Tablet in managing your condition. By staying informed and following medical guidance, you can maximize the benefits of this treatment while minimizing potential risks.
Benefits
Tofajak XR Tablet offers several benefits in the treatment of various conditions. In patients with rheumatoid arthritis, the medication works by blocking inflammatory chemicals, which helps to reduce pain, stiffness, and swelling in the joints. By slowing down the progression of bone and joint damage, it enables individuals to perform daily activities with greater ease, ultimately enhancing their quality of life. Consistency is key when taking this medicine as it should be consumed at the same time daily to maximize its benefits. Even if symptoms improve, it is important to continue the treatment to prevent future harm and maintain symptom relief.
For individuals with psoriatic arthritis, a form of arthritis linked to psoriasis, Tofajak XR Tablet effectively alleviates joint pain, stiffness, and swelling associated with the condition. By enhancing flexibility and impeding disease progression, it plays a vital role in managing psoriatic arthritis and improving patients' overall quality of life.
Moreover, in the case of ankylosing spondylitis, a rare type of arthritis impacting the spine and larger joints, Tofajak XR Tablet helps in reducing pain, stiffness, and swelling. By enhancing flexibility and preventing disease advancement, this medication offers patients the opportunity to lead a more active and fulfilling life.
Additionally, for individuals suffering from ulcerative colitis, a condition affecting the large intestine and rectum, Tofajak XR Tablet proves to be beneficial. By relieving symptoms such as bleeding, frequent diarrhea, and abdominal pain, it not only provides immediate relief but also aids in preventing the recurrence of these symptoms. It is advised to maintain proper hydration by consuming ample fluids while on this medication to maximize its efficacy.
Overall, Tofajak XR Tablet's efficacy in treating rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis lies in its ability to reduce inflammation, manage symptoms, improve flexibility, and prevent disease progression, ultimately enhancing the quality of life for individuals suffering from these conditions.
How to use the Tofajak XR Tablet
To use Tofajak XR Tablet, follow your doctor's instructions on the dose and duration. Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet. You can take Tofajak XR Tablet with or without food, but it's best to take it at the same time each day for consistent results.
For TOFAJAK 5MG TABLET, take it as directed by your physician. Swallow the tablet with a glass of water. You can also crush it and take it with water if needed. Avoid chewing the tablet. Your doctor will determine the right dosage and duration based on factors like your age, medical condition, and weight. Follow your doctor's guidance for the best results.
Uses of Tofajak XR Tablet
Tofajak XR Tablet is commonly used in the treatment of various conditions, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. These conditions can cause discomfort and pain in the joints and sometimes inflammation in the digestive tract. Tofajak XR Tablet helps in relieving symptoms and managing these conditions effectively by reducing inflammation and pain. It is also used for treating polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis in young patients. The medication's effectiveness in targeting these specific conditions makes it a valuable option for individuals seeking relief and management of these health issues.
What conditions Tofajak XR Tablet treats?
Tofajak XR Tablet is used to treat rheumatoid arthritis, an autoimmune disease that causes joint pain, swelling, stiffness, and loss of joint function. It also helps with psoriatic arthritis, an inflammatory arthritis related to psoriasis that affects large joints in the lower extremities and distal joints of toes and fingers. Additionally, the tablet can address ulcerative colitis, a chronic inflammatory bowel disease that leads to inflammation and ulcers in the colon. Symptoms may include bloody stools, stomach pain, diarrhea, and weight loss, along with other related issues like joint pain and skin problems.
Should you consult a doctor?
Seek a doctor's guidance before using Tofajak XR Tablet if you have a severe bloodstream infection or any infection symptoms like fever, chills, cough, or weight loss. Inform your doctor if you have conditions such as diabetes, HIV/AIDS, weak immune system, or a history of recurrent infections. Not recommended for individuals with cancer, smoking habits, lactose intolerance, diverticulitis, ulcers, high cholesterol, or increased risk of blood clots.
Consult a doctor before taking Tofajak XR Tablet if planning to get vaccinated, have had major surgery, or are under 2 years old. If experiencing any of these conditions or symptoms, seeking medical advice is crucial for appropriate treatment and management.
Side effects of Tofajak XR Tablet
When taking Tofajak XR Tablet, you may experience some side effects, although most will not require medical attention and tend to lessen as your body adjusts to the medication. It is essential to consult your doctor if any of the following side effects persist or concern you: upper respiratory tract infection, headache, diarrhea, nasopharyngitis (which is an inflammation of the throat and nasal passages). Other potential side effects include vomiting, nausea, cold symptoms, high blood pressure, signs of kidney problems, skin infections or irritation, cold sores, low white blood cells, liver issues, increased cholesterol, weight gain, dehydration, muscle strain, joint pain and inflammation, abnormal sensations, sleep disturbances, sinus congestion, breathing difficulties, fatty liver, digestive issues like diverticulitis, viral infections, various skin cancers, lung conditions, shingles, urinary tract infections, sore throat, muscle problems, stomach pain, indigestion, anaemia, fatigue, swelling in extremities, cough, rash, blood infections, lymphoma, tuberculosis, joint infections, and other unusual infections. In case you experience severe side effects like serious infections, ulcers, allergic reactions, blood clots, or heart attack symptoms, it is crucial to stop taking the medication immediately and seek medical attention.
Safety advice

liver
Caution should be exercised when using Tofajak XR Tablet in patients with severe liver disease. It may be necessary to adjust the dosage of Tofajak XR Tablet in such cases, so it is important to consult your doctor before taking this medication. Patients with liver impairment should also seek medical advice before using Tofajak XR Tablet. It is not recommended to use Tofajak XR Tablet 10's in patients with severe liver problems. If you have any concerns about your liver health or if you have liver impairment, it is crucial to discuss this with your healthcare provider before starting Tofajak XR Tablet.

kidney
Tofajak XR Tablet may need dose adjustment for patients with severe kidney disease. Consult your doctor if you have kidney impairment or concerns.

alcohol
When taking Tofajak XR Tablet, there are no harmful side effects known from drinking alcohol. However, it's uncertain whether alcohol interacts with Tofajak XR Tablet 10's, so it's advisable to consult with a doctor beforehand.

driving
When taking Tofajak XR Tablet 10's, it is usually safe to drive. However, only drive or operate machinery when you are fully alert.

pregnancy
Tofajak XR Tablet is not safe to use during pregnancy. It may harm the developing baby based on animal studies. Your doctor will assess the risks and benefits before prescribing it. Avoid using Tofajak XR Tablet during pregnancy. If you are a woman who can bear children, use effective contraception during treatment and for 4 weeks after stopping the medication.

breastfeeding
It is probably unsafe to use Tofajak XR Tablet while breastfeeding, as limited data suggests it may pass into breastmilk and harm the baby. It is advised to avoid breastfeeding while taking this medication and consult a doctor if you have concerns.
Age above 75(Geriatrics)
Consumption warning before consuming Tofajak XR Tablet
Before taking Tofajak XR Tablet 10's, it is important to note certain precautions. Do not use this medication if you are allergic to any of its components. Additionally, if you have conditions like severe liver problems (cirrhosis), active tuberculosis, severe infection, or bloodstream infection, avoid taking Tofajak XR Tablet 10's. It is also not suitable for use during pregnancy or breastfeeding.
Inform your doctor if you have any infections, symptoms of infections, or any medical conditions that may increase your risk of infections. Disclose if you are taking any medications that affect the immune system or have a history of tuberculosis. Individuals with chronic lung disease, liver problems, hepatitis B/C, cancer, kidney problems, heart issues, high cholesterol, high blood pressure, diabetes, or blood clotting problems should exercise caution. Avoid Tofajak XR Tablet 10's if your white blood cell count or red blood cell count is low.
This medication is not recommended for children under 18 years old due to a lack of established safety and effectiveness. Keep your doctor informed about your health status and ongoing medications to prevent any potential side effects.
Disease interactions
When taking Tofajak XR Tablet, it is crucial to inform your doctor if you have certain medical conditions. These include infections, bloodstream infection, severe liver problems, tuberculosis, blood clot problems, diabetes, high cholesterol, intestinal perforation, or gastrointestinal obstruction. It is important to disclose these conditions to your doctor to ensure the safe and effective use of Tofajak XR Tablet.
What if you forgot to take Tofajak XR Tablet?
If you forget to take a dose of Tofajak XR Tablet, aim to take it as soon as you remember. However, if it's nearly time for your next scheduled dose, it's best to skip the missed dose and wait for the next one. It's important not to take a double dose to make up for the missed one. This ensures you maintain a consistent and safe dosage schedule for the medication.
What happens if you take overdose of Tofajak XR Tablet?
In the case of an overdose of Tofajak XR Tablet, which contains 5mg of active ingredient, it is important to seek immediate medical attention. Taking more than the prescribed amount can lead to serious health risks. If you or someone else has ingested an excessive dose of this medication, contact your doctor right away or go to the nearest hospital for urgent treatment. It is crucial to address an overdose promptly to prevent any potential complications and ensure proper care and support is provided.
Related lab tests
Related Lab Tests:
When taking Tofajak XR Tablet, your doctor may recommend certain lab tests to monitor your health and the effectiveness of your treatment. These tests can help assess any potential side effects and how well the medication is working for your condition. Here are some related lab tests that may be requested:
1. C-Reactive Protein Quantitative: This test measures the level of inflammation in your body, which can be helpful in monitoring conditions such as rheumatoid arthritis or other inflammatory disorders.
2. Erythrocyte Sedimentation Rate: Also known as ESR, this test measures the rate at which red blood cells settle in a tube of blood. It can also indicate the presence of inflammation in the body.
3. HLA-B27, PCR: This test helps in the diagnosis of conditions like ankylosing spondylitis and other autoimmune diseases.
4. Rheumatoid Factor - Agglutination and Rheumatoid Factor - Turbidometry: These tests detect the presence of antibodies that are often found in patients with rheumatoid arthritis.
5. Rheumatoid Factor IgG Antibody: This test specifically looks for IgG antibodies associated with rheumatoid arthritis.
In addition to these specific lab tests, your doctor may also recommend other tests such as X-rays, MRIs, complete blood count, skin tests, and liver/kidney function tests to assess your overall health and the impact of Tofajak XR Tablet on your body. It is important to follow your doctor's recommendations for lab testing to ensure the safe and effective use of this medication.
Additional Information
| Habit Forming | No |
| Chemical Class | Pyrrolo Pyrimidine Derivative |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Janus kinase inhibitors |
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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 11-Feb-2025
