Sitazit-M ER 500 Tablet
By Sitazit-M
Rx
10 Tablet ER in a Strip

Composition
Sitagliptin(100mg) + Metformin(500mg)

Manufacturer - Glenmark Pharmaceuticals Ltd
Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Expires on or after
June, 2026
About Sitazit-M ER 500 Tablet
Sitazit-M ER 500 Tablet is a medication that combines two drugs, Sitagliptin and Metformin, to help manage high blood sugar levels in individuals with type 2 diabetes mellitus. This combination is particularly beneficial in preventing serious complications associated with diabetes, such as kidney damage, blindness, and reducing the risk of heart attacks and strokes.
It is recommended to take Sitazit-M ER 500 Tablet as per your doctor's prescription, either on its own or in combination with other diabetes medications. For optimal results, it is advised to take the medication consistently at the same time each day, preferably with meals to minimize the likelihood of an upset stomach. Additionally, maintaining a healthy diet and regular exercise routine are crucial while using this medication, as lifestyle choices significantly impact diabetes control.
Common side effects of Sitazit-M ER 500 Tablet may include diarrhea, nausea, vomiting, upset stomach, headache, and sore throat. There is also a potential risk of low blood sugar levels (hypoglycemia), especially when taking other diabetes medications concurrently like insulin or sulfonylurea. It is important to be aware of the signs of hypoglycemia and know how to manage it effectively.
Before starting Sitazit-M ER 500 Tablet, it is essential to inform your doctor of any history of kidney, liver, or heart disease, pancreatic issues, or excessive alcohol consumption. Pregnant or breastfeeding individuals should seek medical advice before initiating this medication. Furthermore, it is crucial to disclose all other medications you are taking to ensure compatibility with Sitazit-M ER 500 Tablet.
Regular monitoring of kidney function and blood sugar levels is typically recommended by your healthcare provider throughout the treatment course. Skipping doses or discontinuing the medication without consulting your doctor can adversely affect blood sugar levels and increase the risk of diabetes-related complications. Sitazit-M ER 500 Tablet is not suitable for individuals with certain medical conditions, such as type 1 diabetes mellitus, severe kidney or liver disease, and specific heart conditions.
Overall, Sitazit-M ER 500 Tablet offers an effective treatment option for managing type 2 diabetes mellitus when used in conjunction with a well-rounded approach that includes medication adherence, healthy lifestyle habits, and ongoing medical supervision.
Benefits
Sitazit-M ER 500 Tablet offers several benefits in the treatment of Type 2 diabetes mellitus. This medication combines two powerful medicines that work in harmony to effectively lower blood glucose levels, which is crucial for managing diabetes. By keeping your blood glucose levels under control with Sitacip M, you can significantly reduce the risk of developing serious complications associated with diabetes such as kidney damage, eye problems, nerve issues, and potential limb amputation. Properly managing diabetes with this medication can also lower the risk of heart disease and stroke, promoting overall heart health.
One of the key components in Sitacip M is Sitagliptin, which acts by blocking the action of DPP-4, an enzyme that breaks down the hormone Incretin. Incretins play a vital role in producing more insulin only when needed and reducing excess blood sugar produced by the liver. By regulating blood sugar levels effectively, Sitacip M helps prevent severe diabetes-related complications like retinopathy (eyesight loss), nephropathy (kidney problems), neuropathy (nerve damage), diabetic foot ulcers, and slow wound healing.
It is important to take Sitacip M regularly as prescribed, in conjunction with a proper diet and exercise regimen, to experience its full benefits. By incorporating this medication into your daily routine, you can enhance your quality of life and lower the likelihood of future health issues related to diabetes. Trust in Sitacip M to protect your well-being and help you lead a normal and healthy lifestyle.
How to use the Sitazit-M ER 500 Tablet
To use Sitazit-M ER 500 Tablet, follow your doctor's instructions on dosage and duration. Take the tablet by mouth and swallow it whole with water. Remember not to chew, crush, or break the tablet. It is important to take Sitazit-M ER 500 Tablet with food. By following these guidelines, you can ensure the medication is effective and safe for your body. If you have any questions or concerns about how to use Sitazit-M ER 500 Tablet, consult your doctor for further guidance.
Uses of Sitazit-M ER 500 Tablet
'Sitazit-M ER 500 Tablet' is a medication indicated for the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus, a condition characterized by high levels of blood sugar, is a chronic disease that requires ongoing management to control blood glucose levels. This medication is prescribed to help individuals with Type 2 diabetes mellitus maintain proper blood sugar control. By taking Sitazit-M ER 500 Tablet as directed by a healthcare professional, patients can effectively manage their diabetes and minimize the risk of complications associated with uncontrolled blood sugar levels. It is important for individuals with Type 2 diabetes mellitus to follow their healthcare provider's recommendations and treatment plan, including the appropriate use of Sitazit-M ER 500 Tablet, to effectively manage their condition.
What conditions Sitazit-M ER 500 Tablet treats?
Sitazit-M ER 500 Tablet is used to manage type 2 diabetes. This condition arises when the body cannot produce enough insulin or the insulin is not working effectively. Due to this, high blood sugar levels may occur, leading to symptoms like excessive thirst, frequent urination, slow wound healing, increased hunger, fatigue, and blurred vision. Complications of type 2 diabetes can include nerve problems, kidney issues, damaged retina or blindness, loss of limbs, sexual dysfunction, and an increased risk of heart attack or stroke.
Should you consult a doctor?
Seek medical attention if you experience persistent side effects like vomiting, diarrhea, or hypoglycemia (low blood sugar), as these may indicate a need for dosage adjustment. Contact your doctor if you have a decreased appetite, upper respiratory tract infection, or abdominal bloating which persist. Inform your healthcare provider immediately if you have a history of kidney, liver, or heart disease, pancreas issues, or excessive alcohol consumption. Pregnant or nursing women should consult their doctor before taking Sitazit-M ER 500 Tablet. In case of any concerns or if you are unsure about any symptoms, it is important to seek medical advice to ensure your well-being and proper management of diabetes. Remember to inform your doctor about all medications you are taking to prevent any potential interactions or complications. Regular monitoring of kidney function and blood sugar levels is essential during treatment to ensure safety and effectiveness.
Side effects of Sitazit-M ER 500 Tablet
Side Effects:
Sitazit-M ER 500 Tablet may cause side effects in some individuals. Most side effects are temporary and may go away as your body gets used to the medication. However, if the following side effects persist or cause concern, it is important to consult your doctor for guidance.
1. Decreased Appetite: Some individuals may experience a decreased appetite while taking Sitazit-M ER 500 Tablet. This can lead to a reduced desire to eat or a feeling of fullness sooner than usual.
2. Vomiting and Nausea: Vomiting and nausea are possible side effects of Sitazit-M ER 500 Tablet. These symptoms involve feeling sick to your stomach and may lead to throwing up.
3. Abdominal Bloating: Abdominal bloating, which is a feeling of fullness or tightness in the stomach area due to excess gas, may occur with the use of this medication.
4. Diarrhea: Some individuals may experience diarrhea while taking Sitazit-M ER 500 Tablet. Diarrhea involves loose or watery stools and may occur more frequently than usual.
5. Hypoglycemia (Low Blood Glucose Level): Another potential side effect of this medication is hypoglycemia, which is characterized by low levels of sugar in the blood. It is important to monitor your blood sugar levels closely if you experience symptoms such as weakness, sweating, or confusion.
6. Upper Respiratory Tract Infection: Sitazit-M ER 500 Tablet may increase the risk of upper respiratory tract infections, such as nasopharyngitis (infection of the nose and throat) and common cold symptoms like a sore throat or runny nose.
7. Headache: Headaches may also arise as a side effect of Sitazit-M ER 500 Tablet. These headaches may vary in intensity and can be accompanied by other symptoms such as sensitivity to light or sound.
If you experience any of these side effects and they persist or become concerning, it is advisable to seek medical advice from your healthcare provider.
Safety advice

liver
Sitazit-M ER 500 Tablet should be avoided by patients with liver disease as it is considered to be unsafe for them. It is important to consult with your doctor before using this medication to ensure your safety.

kidney
Sitazit-M ER 500 Tablet should be used carefully if you have kidney disease. Your doctor may need to adjust the dose. Avoid using it if you have severe kidney problems. Regular kidney function tests are advised during treatment.

alcohol
It is advised not to drink alcohol when taking Sitazit-M ER 500 Tablet.

driving
Do not drive if you experience low or high blood sugar while taking Sitazit-M ER 500 Tablet, as it may impact your ability to drive safely.

pregnancy
Sitazit-M ER 500 Tablet may not be safe to use during pregnancy. Studies in animals have shown harmful effects on the developing baby. Your doctor will consider the benefits and risks before prescribing. Please consult your doctor before using Sitazit-M ER 500 Tablet during pregnancy.

breastfeeding
Sitazit-M ER 500 Tablet may be unsafe during breastfeeding as it might pass into breastmilk and harm the baby.
Consumption warning before consuming Sitazit-M ER 500 Tablet
Before taking Sitazit-M ER 500 Tablet, inform your doctor if you are allergic to sitagliptin, any medications, foods, or any components in the tablet. Regular use of Sitazit-M ER 500 Tablet may lead to acute pancreatitis or serious kidney issues. Be cautious as combining Sitazit-M ER 500 Tablet with other anti-diabetic medications or insulin can elevate the risk of hypoglycemia. If necessary, your doctor will adjust the dosage accordingly. Some individuals may experience severe allergic reactions such as anaphylaxis, angioedema, or skin conditions like Stevens-Johnson syndrome while taking this medication. It is essential to note that the safety and effectiveness of Sitazit-M ER 500 Tablet have not been confirmed in individuals under 18 years old; therefore, they should not use it. Patients using digoxin for heart conditions alongside Sitazit-M ER 500 Tablet must be carefully monitored due to potential severe drug interactions.
Disease interactions
When considering taking Sitazit-M ER 500 Tablet, it is important to note its interactions with certain medical conditions. Patients with a history of pancreatitis or pancreatic disease should use this medication with caution. Similarly, individuals with renal dysfunction should also be cautious when taking Sitazit-M ER 500 Tablet. It is advised to consult with a healthcare provider before starting this medication if you have a history of these conditions to ensure its safe use.
What if you forgot to take Sitazit-M ER 500 Tablet?
If a dose of Sitazit-M ER 500 Tablet is missed, it is advisable to take it as soon as you remember. However, if it is near the time for the next scheduled dose, you should skip the missed dose and continue with your usual dosing schedule. It is important not to double up on doses to make up for the missed one. If you have any concerns or questions about missed doses, always consult your healthcare provider for guidance.
Related lab tests
When taking Sitazit-M ER 500 Tablet, it is important to monitor your glucose levels regularly to ensure your body is responding well to the medication. The following related lab tests can provide valuable information about your blood sugar levels:
1. Glucose - Fasting Blood Test: This test measures the amount of sugar in your blood after fasting for at least 8 hours. It helps to evaluate your baseline glucose levels.
2. Glucose - Postprandial Blood Test: This test measures your blood sugar levels 2 hours after a meal. It provides information on how your body processes glucose after eating.
3. Glycosylated Hemoglobin Test: Also known as HbA1c, this test reflects your average blood sugar levels over the past 2-3 months. It is a crucial indicator of long-term blood sugar control.
Regular monitoring of these lab tests can help you and your healthcare provider assess the effectiveness of Sitazit-M ER 500 Tablet in managing your blood sugar levels.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | ANTI DIABETIC |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹196
Inclusive of all taxes
Content verified by

Dr. Mansi Chaudhari
MBBS - General Medicine
Last update on 01-Oct-2024