Simbrinza Ophthalmic Suspension
By Simbrinza
Rx
5ml Ophthalmic Suspension in a Packet

Composition
Brinzolamide(1% w/v) + Brimonidine(0.2% w/v)

Manufacturer - Alcon Laboratories
54/1, Boodhihal, Nelamangala, Bangalore, -562123, Karnataka, India

Expires on or after
March, 2027
About Simbrinza Ophthalmic Suspension
Simbrinza Ophthalmic Suspension is a prescription medicine specifically formulated to treat glaucoma, a condition characterized by increased pressure in the eye. It contains a combination of two active ingredients, Brimonidine and Brinzolamide, which work together to reduce the production of aqueous humor in the eye. By lowering the fluid pressure within the eye, Simbrinza helps alleviate the symptoms associated with glaucoma and ocular hypertension.
This medication should only be used as directed by a healthcare professional, typically in the affected eye. It is important to wash your hands before administering the eye drops and carefully follow the instructions provided on the label. Consistency in using Simbrinza is crucial, even if you start feeling better, to ensure the full course of treatment is completed effectively.
As with any medication, Simbrinza Ophthalmic Suspension may cause some side effects. Common ones include a burning sensation, irritation, itching, and redness at the application site. In case of prolonged or severe side effects, it is advisable to seek medical advice. Additionally, if the suspension accidentally comes into contact with your ears, nose, or mouth, rinse it off immediately with water to prevent any adverse reactions.
It is essential to note that Simbrinza Ophthalmic Suspension can cause temporary blurring of vision, so activities such as driving or operating heavy machinery should be avoided right after using the medicine. Furthermore, individuals with liver, kidney, or heart conditions, along with those dealing with low or high blood pressure, narrow-angle glaucoma, dry eyes, depression, or circulation issues, should inform their doctor before using this medication. Pregnant or breastfeeding individuals should also consult their healthcare provider before starting treatment with Simbrinza Ophthalmic Suspension.
Benefits
Simbrinza Ophthalmic Suspension provides key benefits in the treatment of glaucoma, a serious eye disease that damages the optic nerve and can lead to vision loss. By reducing swelling and pressure inside the eye, Simbrinza Ophthalmic Suspension helps prevent complications of glaucoma such as blindness and enhances vision. This medication contains two effective drugs, Brinzolamide and Brimonidine, which work together to lower high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. The combination of these drugs decreases the production of aqueous humor, which in turn helps alleviate the increased pressure in the eye. Simbrinza Ophthalmic Suspension can be used alone or in combination with other eye drops for optimal results. Regular monitoring and checkups are important for early detection of glaucoma since the disease cannot be prevented. By using Simbrinza Ophthalmic Suspension as directed by healthcare professionals, patients can effectively manage their condition and safeguard their vision.
How to use the Simbrinza Ophthalmic Suspension
When using Simbrinza Ophthalmic Suspension, always follow your doctor's instructions on dosage and duration. Before using, check the label for specific directions. To administer the medication, hold the dropper close to your eye without touching it, gently squeeze to place the drops inside the lower eyelid, and then wipe off any excess liquid.
For optimal results, lie down and tilt your head back. Gently pull down your lower eyelid with your index finger to create a pocket. Follow the doctor's guidance on the number of drops to instil into the pocket of the lower eyelid. Close your eyes for 1-2 minutes after application.
Remember, Simbrinza Ophthalmic Suspension is meant for eye use only. Before use, wash your hands thoroughly. After instilling a few drops into the affected eye, close your eyes and gently press the corner of your eye with your finger for a minute. Be careful not to touch the dropper tip to your eye or any other surface to prevent contamination.
When using Simbrinza Ophthalmic Suspension, wait at least 5 minutes before applying any other eye drops or ointments. If you wear soft contact lenses, remove them before using the medication and wait at least 15 minutes before reinserting them. Your doctor will determine the proper dosage and duration of therapy based on factors such as your age, weight, and medical condition.
It's essential to continue using Simbrinza Ophthalmic Suspension as prescribed and not to stop treatment without consulting your doctor. Abruptly stopping the medication could result in an increase in eye pressure.
Uses of Simbrinza Ophthalmic Suspension
Simbrinza Ophthalmic Suspension is used to treat adults with open-angle glaucoma or ocular hypertension. It effectively treats the conditions of ocular hypertension and glaucoma by reducing the pressure inside the eye. By using Simbrinza Ophthalmic Suspension as prescribed, patients can manage their eye conditions and potentially prevent further damage to their vision.
What conditions Simbrinza Ophthalmic Suspension treats?
Glaucoma is an eye condition that can lead to damage of the optic nerve from increased pressure in the eye. It can cause blindness if left untreated. Glaucoma often shows no symptoms at first but can cause a gradual loss of vision. Some signs may include seeing rainbow-colored circles around lights or having blurred vision. In rare cases, glaucoma can suddenly appear with severe eye pain, sight problems, or nausea. Ocular hypertension is another condition where fluid build-up in the eye increases pressure but doesn't immediately harm the optic nerve, potentially leading to glaucoma if not managed.
Should you consult a doctor?
If you experience any worsening of symptoms or have concerns while using Simbrinza Ophthalmic Suspension, it is important to seek medical advice promptly. Contact your healthcare provider if you have conditions like dry eyes, cornea issues, narrow angle glaucoma, high or low blood pressure, depression, poor blood circulation, reduced blood supply to the brain, or wear soft contact lenses. Additionally, if you develop hyperchloremic acidosis (excessive blood acidity), you should not use Simbrinza Ophthalmic Suspension without consulting your doctor. Regular monitoring and communication with your healthcare professional can help ensure the safe and effective use of this medication.
Side effects of Simbrinza Ophthalmic Suspension
When using Simbrinza Ophthalmic Suspension, you may experience certain side effects. These can include reactions at the application site such as burning, irritation, itching, and redness. You may also notice symptoms like blurred or abnormal vision, eye redness, discomfort, drowsiness, a bad taste in the mouth, dry mouth, dizziness, eye surface inflammation, and eye pain. Other possible side effects include eye swelling, watery eyes, sensitivity to sunlight, low blood pressure, feelings of depression, weakness, nervousness, or irritability, shortness of breath, nose bleeds, a runny nose, sore throat, cough, cold, nasal dryness, sneezing, ringing in the ears, nausea, vomiting, skin rash, itching, hair loss, muscle pain or spasms, low sex drive, problems with erection, and more eye-related issues like redness, itching, inflammation, pain, discomfort, and blurred vision. It is important to contact your doctor if any of these side effects persist or if you are concerned about them. However, if you experience severe side effects such as pale skin, sleepiness, low body temperature, breathing difficulties, or serious allergic reactions like skin rash, swelling of the eye, eyelids, face, lips, tongue, hands, or throat that lead to difficulty in breathing, stop using Simbrinza Ophthalmic Suspension immediately and seek medical attention.
Safety advice

liver
It has been determined that there are no interactions between Simbrinza Ophthalmic Suspension and liver issues. As such, there are no specific safety concerns or advice related to the liver when using this medication. If you have any additional questions or concerns about how Simbrinza Ophthalmic Suspension may affect your liver, it is advised to consult with your doctor for proper guidance.

kidney
No interaction found with kidney issues.

alcohol
No interactions have been found or established between alcohol and Simbrinza Ophthalmic Suspension. It is recommended to consult your doctor if consuming alcohol with Simbrinza Ophthalmic Suspension. It is advised to be cautious during pregnancy.

driving
After using Simbrinza Ophthalmic Suspension, your vision may be blurry briefly. Wait until your vision is clear before driving.

pregnancy
Information on the use of Simbrinza Ophthalmic Suspension during pregnancy is not available. It is recommended to consult with your doctor before using this medication while pregnant.

breastfeeding
It is better to consult your doctor before using Simbrinza Ophthalmic Suspension during breastfeeding.
Age above 75(Geriatrics)
Simbrinza Ophthalmic Suspension should be used with caution in elderly patients. Therefore, consult your doctor before using it.
Age below 6 months(Pediatrics)
Simbrinza Ophthalmic Suspension is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it.
Consumption warning before consuming Simbrinza Ophthalmic Suspension
Before using Simbrinza Ophthalmic Suspension, it is crucial to note several warnings. Do not use this medication if you are allergic to any of its ingredients, taking monoamine oxidase inhibitors, or have severe kidney issues or high blood acidity. Inform your doctor if you have liver problems, narrow-angle glaucoma, dry eyes, cornea issues, heart disease, depression, or blood circulation problems. Prior consultation with a healthcare provider is essential if you are pregnant, breastfeeding, or considering using this product in children under 18 years old, as its safety and effectiveness in these groups have not been conclusively established. Be aware that Simbrinza Ophthalmic Suspension may lead to dizziness, drowsiness, or vision disturbances. It is advised to avoid driving if experiencing these symptoms.
Disease interactions
In regards to disease drug interactions with Simbrinza Ophthalmic Suspension, it is important to inform your doctor if you have certain health conditions. Specifically, individuals with severe kidney problems, depression, heart problems, or excess acidity in the blood should notify their healthcare provider before using this medication. By being transparent about these conditions, your doctor can assess the potential risks and benefits of using Simbrinza Ophthalmic Suspension to ensure your safety and well-being.
What if you forgot to take Simbrinza Ophthalmic Suspension?
If you forget to use a dose of Simbrinza Ophthalmic Suspension, simply skip that dose and resume your regular dosing schedule. It's important not to take an extra dose to make up for the missed one. Just wait until the next scheduled dose. Your eye doctor can provide further guidance if needed.
What happens if you take overdose of Simbrinza Ophthalmic Suspension?
In the case of accidental overdose of Simbrinza Ophthalmic Suspension, prompt action is necessary. If the medication gets in the eye, rinse it with warm water. If irritation continues, seek medical advice. If swallowed mistakenly, contact your doctor right away. Overdose symptoms may include slow heartbeat, changes in blood pressure, breathing difficulties, and neurological issues like confusion.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | - |
Action Class | - |
FAQs
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₹710
Inclusive of all taxes
Content verified by

Dr. Upasana Bhatia
MBBS - General Medicine
Last update on 01-Oct-2024