Silival-OD 500 Tablet
By Silival
Rx
10 Tablet SR in a Strip

Composition
Divalproex(500mg)

Manufacturer - Silicon Pharma
B-18, Galaxy Signature, Opp. Shukan Bunglows, Science City Road, Ahmedabad-380060. (Guj.)

Expires on or after
September, 2025
About Silival-OD 500 Tablet
Silival-OD 500 Tablet is a medication primarily used for the treatment of epilepsy, a condition characterized by recurring seizures or fits. Additionally, it is beneficial in preventing and managing migraines, and in some cases, it can be prescribed for individuals with bipolar disorder. This medication can be taken alone or in combination with other medicines, with the dosage and frequency determined by a healthcare professional to effectively manage symptoms. It is recommended to take Silival-OD 500 Tablet at the same time each day, whether with or without food, for optimal results.
The effectiveness of Silival-OD 500 Tablet typically becomes noticeable after a few weeks of consistent use. It is crucial to adhere to the prescribed regimen for the entire duration advised by the healthcare provider, even if symptoms improve. Abruptly stopping this medication can exacerbate the underlying condition and potentially trigger seizures. Common side effects of Silival-OD 500 Tablet may include headaches, blurred vision, nausea, vomiting, dizziness, fatigue, unsteadiness, bruising, and reduced body temperature. While these are typically mild, any persistent or bothersome side effects should be discussed with a doctor. Immediate medical attention is necessary if a skin rash or redness develops.
Long-term use of Silival-OD 500 Tablet has the potential to lead to osteoporosis and increase the risk of bone fractures. In rare cases, this medication may contribute to suicidal thoughts or behaviors, particularly if mood changes occur. Patients with a history of heart issues, kidney or liver disease, urinary problems, depression, or suicidal tendencies should inform their doctor before starting Silival-OD 500 Tablet. It is essential to disclose all medications being taken to prevent potential interactions.
Individuals who are pregnant should consult their healthcare provider before initiating or discontinuing Silival-OD 500 Tablet. Alcohol consumption should be avoided while using this medication, as it can heighten side effects and the risk of seizures. Regular blood tests may be necessary to monitor the appropriate dosage of Silival-OD 500 Tablet.
Benefits
Silival-OD 500 Tablet offers multiple benefits in various medical conditions.
In the treatment of epilepsy/seizures, this medication acts as an anticonvulsant, working to reduce the nerve impulses that cause seizures. By controlling the frequency of seizures, Silival-OD 500 Tablet enables individuals to carry out their daily activities with increased confidence. It helps alleviate symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. Importantly, this medicine is not linked to physical or psychological dependence, but it should be taken regularly as prescribed for optimal effectiveness, as missing doses may trigger a seizure.
For individuals managing bipolar disorder, Silival-OD 500 Tablet plays a crucial role in restoring the normal balance of nerve activity in the brain. By stabilizing mood swings, this medication helps prevent extreme changes in mood and reduces feelings of agitation. While it may take several weeks to observe the full benefits, using Silival-OD 500 Tablet consistently over at least six months, or potentially longer, can lead to fewer low mood episodes. It is essential to continue taking the medication as directed by a healthcare provider and prioritize healthy habits such as proper nutrition and exercise to reduce symptoms associated with bipolar disorder.
Additionally, Silival-OD 500 Tablet offers benefits in the prevention of migraines, although the exact mechanism is still being understood. It is believed to modulate abnormal nerve cell activity in the brain or enhance activity in regions associated with migraines. By averting and decreasing the frequency of headaches, this medication helps individuals engage in their daily routines and improve their overall quality of life.
In summary, Silival-OD 500 Tablet provides valuable therapeutic effects in managing epilepsy/seizures, bipolar disorder, and migraine prevention by regulating nerve activity in the brain, stabilizing mood, and reducing headache occurrences. Following the prescribed dosage and treatment regimen is essential for leveraging the full benefits of this medication and enhancing overall well-being.
How to use the Silival-OD 500 Tablet
To use Silival-OD 500 Tablet, follow your doctor's instructions on the dose and duration. Make sure to swallow the tablet whole with water, without chewing, crushing, or breaking it. While you can take this medication with or without food, it is recommended to take it at the same time each day for consistency. If you are using the oral suspension form, remember to shake the bottle well before each use and take the prescribed dose by mouth using the provided measuring cup, dosing syringe, or dropper. Your physician will determine the right dosage and treatment duration based on factors such as your age, body weight, and the specific condition being treated. Always consult your doctor for personalized guidance on how to use Silival-OD 500 Tablet effectively.
Uses of Silival-OD 500 Tablet
Silival-OD 500 Tablet is commonly used for treating epilepsy or seizures, bipolar disorder, and migraines. It is effective in managing mania and bipolar disorder symptoms, as well as in treating complex partial seizures, either alone or in combination with other types of seizures. Additionally, this medication is also used for the prevention of migraines. It helps in controlling the frequency and intensity of these conditions, offering relief to individuals suffering from epilepsy, bipolar disorder, and migraines.
What conditions Silival-OD 500 Tablet treats?
Silival-OD 500 Tablet is used to treat epilepsy. Epilepsy is a nervous system disorder caused by abnormal nerve cell activity in the brain. It leads to imbalanced electrical rhythms in the brain, resulting in recurrent seizures. These seizures can affect an individual's consciousness, movements, or sensations. There are two types of seizures: generalized, involving the entire brain, and partial, involving only a part of the brain. Seizures can cause muscle cramps, spasms, confusion, or unconsciousness. Possible causes include high fever, trauma, genetic disorders, brain injuries, or stroke.
Should you consult a doctor?
It is essential to seek medical attention before taking Silival-OD 500 Tablet if you have certain health conditions. Do not take this medication if you have POLG and its associated disorder, particularly in children under 2 years old, or urea cycle disorders. Before starting Silival-OD 500 Tablet, inform your doctor if you have systemic lupus erythematosus, porphyria, bleeding or other blood disorders, pancreatitis, hyperammonemia, hyperammonemic encephalopathy, or DRESS syndrome. If you experience any symptoms related to these conditions while taking Silival-OD 500 Tablet, promptly consult your healthcare provider for further evaluation and guidance.
Side effects of Silival-OD 500 Tablet
When taking Silival-OD 500 Tablet, some common side effects may occur as your body gets used to the medication. These can include feeling dizzy, sleepy, or experiencing tremors. You may also notice tingling sensations, changes in body temperature, or gastrointestinal disturbances. In some cases, side effects such as anemia, liver injury, or hypersensitivity reactions like deafness or urinary incontinence may occur. Other possible side effects could include weight gain, menstrual pain, and stomach issues like nausea, vomiting, or diarrhea. Additionally, some individuals may experience symptoms such as hair loss, fatigue, or blurry vision while on this medication. It is essential to speak with your doctor if any side effects persist or cause concern. If you encounter severe side effects like bleeding problems, high ammonia levels in the blood, or allergic reactions, it is crucial to contact your physician immediately. Furthermore, if you experience thoughts of harming yourself or any concerning symptoms related to your health, seek medical attention promptly.
Safety advice

liver
Silival-OD 500 Tablet is considered unsafe for individuals with liver disease. It is recommended to avoid using this medication if you have liver issues. Prior consultation with your doctor is advised before taking Silival-OD 500 Tablet.

kidney
Silival-OD 500 Tablet is safe for use in patients with kidney disease, and there is no need for dose adjustment.

alcohol
When taking Silival-OD 500 Tablet, be careful as it can lead to extreme drowsiness when consumed with alcohol.

driving
When taking Silival-OD 500 Tablet, be cautious while driving as it may cause side effects that can impact your driving ability.

pregnancy
Silival-OD 500 Tablet is not safe to use during pregnancy because it poses a risk to the developing baby. Only in life-threatening cases where benefits outweigh risks, a doctor may consider prescribing it. Consult your doctor before use.

breastfeeding
Silival-OD 500 Tablet is considered safe to use while breastfeeding. Research shows that the medication does not transfer into breastmilk in harmful quantities, posing no risk to the baby.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Silival-OD 500 Tablet
Before consuming Silival-OD 500 Tablet, it is crucial to inform your doctor about all your medical conditions, sensitivities, and current medications. It is essential to disclose if you are pregnant, suspect pregnancy, planning to conceive, or breastfeeding. It is advised not to get pregnant during the course of Silival-OD 500 Tablet and notify your doctor promptly if pregnancy occurs. Avoid alcohol intake while on this medication. Refrain from driving or operating machinery while taking Silival-OD 500 Tablet to ensure safety.
Disease interactions
When taking Silival-OD 500 Tablet, it is important to inform your doctor if you have certain medical conditions. Let your doctor know if you have depression, liver disease, urea cycle disorders, suicidal tendencies, HIV disease, hereditary mitochondrial disorders, or thrombocytopenia (low platelets). These conditions can interact with the medication, and your doctor needs to be aware of them to ensure the safety and effectiveness of your treatment.
What if you forgot to take Silival-OD 500 Tablet?
If you forget to take your Silival-OD 500 Tablet, take it when you remember. But if it's almost time for your next dose, just continue with your usual dosing schedule. Do not take double the dose to make up for the missed one.
What happens if you take overdose of Silival-OD 500 Tablet?
In case of overdosing on Silival-OD 500 Tablet, seek immediate medical help from a doctor or the nearest hospital. Overdose symptoms may include feeling excessively drowsy, heart block, and possibly falling into a deep coma. If you suspect an overdose, it is crucial to get prompt medical attention for appropriate treatment and care.
Related lab tests
Related Lab Tests for Silival-OD 500 Tablet may include an Electroencephalogram (EEG) and a Magnetic Resonance Imaging (MRI) test. An EEG is a test that measures electrical activity in the brain through sensors attached to the scalp. This test can help in diagnosing conditions such as seizures, epilepsy, or sleep disorders. On the other hand, an MRI uses powerful magnets and radio waves to create detailed images of the inside of the body, including the brain. It can provide valuable information about any structural abnormalities or conditions that may be affecting the brain. These tests can complement the use of Silival-OD 500 Tablet in diagnosing and monitoring certain neurological conditions.
Additional Information
Habit Forming | No |
Chemical Class | Aliphatic Carboxylic acid Derivatives |
Therapeutic Class | NEURO CNS |
Action Class | Sodium channel modulators (AED) |
FAQs
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Content verified by

Dr. Gowri Kulkarni
MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)
Last update on 11-Feb-2025