Rifalin I 450 mg/300 mg Tablet

By Rifalin I

Rx

10 Tablet in a Strip

Composition icon

Composition

Rifampicin(450mg) + Isoniazid(300mg)

Manufacturer - Lincoln Pharmaceuticals Ltd icon

Manufacturer - Lincoln Pharmaceuticals Ltd

LINCOLN HOUSE, B/h. Satyam Complex, Science City Road, Sola, Ahmedabad – 380 062., Gujarat, India,

Expires on or after icon

Expires on or after

August, 2025

About Rifalin I 450 mg/300 mg Tablet

Rifalin I 450 mg/300 mg Tablet is a blend of Isoniazid and Rifampicin, classified as Antitubercular agents. This medication is primarily used to combat tuberculosis as well as bacterial infections affecting the membranes around the brain and spinal cord. Additionally, it is employed in treating contagious skin diseases, nerve-related infections, mucous membrane conditions, and various other maladies in affected patients.

It is crucial to note that individuals with allergies to Isoniazid, Rifampicin, or related components should avoid using RIFALIN I 450/300MG TABLET. Before commencing the medication, it is essential to inform your healthcare provider if you have an upcoming surgery scheduled or if you are managing pre-existing health conditions, especially liver disorders like cirrhosis or kidney problems such as renal insufficiency.

For pregnant women or those planning pregnancy, caution is advised when using RIFALIN I 450/300MG TABLET. Similarly, breastfeeding mothers should discuss the risks and benefits with their healthcare provider due to the potential transfer of the medication through breast milk. Children and adolescents under 18 years old should use this medication under careful supervision, as should elderly patients aged 65 and above, after consulting their doctor.

Common side effects that may occur when taking RIFALIN I 450/300MG TABLET include hypersensitivity reactions evidenced by skin rash, red itchy welts, or shortness of breath, potential loss of vision or hearing, flu-like symptoms, and joint stiffness known as arthralgia. If any of these symptoms worsen or persist, it is advisable to seek medical consultation promptly.


Benefits

Rifalin I 450 mg/300 mg Tablet, a powerful combination of medications, offers a range of benefits in the treatment of tuberculosis (TB). Tuberculosis is a serious infectious disease that primarily targets the lungs and can also impact other parts of the body. This medication effectively combats the infection-causing bacteria, both by eliminating them and by hindering their growth. By following the prescribed dosage and duration as instructed by your doctor, Eufacin Inh can significantly improve your symptoms, even though they may alleviate before the infection is fully eradicated. It is crucial not to discontinue the medication without consulting your doctor, as doing so could lead to a relapse or worsening of the infection. Adhering closely to your doctor's guidance is essential to ensure that you receive the maximum benefit from this treatment.


How to use the Rifalin I 450 mg/300 mg Tablet

To use Rifalin I 450 mg/300 mg Tablet, it is important to follow your doctor's instructions on dosage and duration. Swallow the tablet whole, without chewing, crushing, or breaking it. It is recommended to take Rifalin I 450 mg/300 mg Tablet on an empty stomach. Additionally, it is advised to avoid consuming tyramine-rich foods like cheese, smoked fish, meats, and certain types of beer while taking this medication. Adhering to these guidelines will help ensure the effectiveness of Rifalin I 450 mg/300 mg Tablet in managing your condition.


Uses of Rifalin I 450 mg/300 mg Tablet

Rifalin I 450 mg/300 mg Tablet is commonly used in the treatment of Tuberculosis (TB). This medication is specifically geared towards addressing TB, a bacterial infection that mainly affects the lungs. It is essential in managing the symptoms of TB and aiding in the eradication of the bacteria causing the infection. The tablet works by targeting and inhibiting the growth of the tuberculosis bacteria, thus helping to control and eliminate the infection. This makes Rifalin I 450 mg/300 mg Tablet a crucial component in the treatment regimen for individuals diagnosed with TB.


What conditions Rifalin I 450 mg/300 mg Tablet treats?

Rifalin I 450 mg/300 mg Tablet is used to treat tuberculosis, a contagious disease that primarily impacts the lungs but can also affect other body parts. It works by eliminating and preventing the growth of bacteria causing the infection. Follow the prescribed dosage and duration diligently. Even if you start feeling better, complete the full course of treatment to prevent the infection from recurring or worsening. Consult your doctor if the condition worsens or does not improve. Symptoms may improve before the infection is fully cleared, so do not stop the medication abruptly.


Should you consult a doctor?

If you experience any unusual or severe side effects such as nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, or allergic reactions like rashes, itching, swelling, or shortness of breath while taking Rifalin I 450 mg/300 mg Tablet for tuberculosis, it is important to seek medical help immediately.

Additionally, if you notice any worsening of your condition or if your symptoms do not improve while on the medication, consult your doctor promptly. Patients with liver or kidney issues should approach their healthcare provider before starting the treatment. Pregnant or nursing women should also seek medical advice before using this medicine.

Remember to take the prescribed dosage at the same time daily on an empty stomach, and complete the full course of treatment as directed, even if you start feeling better. Missing a dose should be compensated for as soon as you remember. If you experience persistent side effects, speak to your doctor for guidance on how to manage them.


Side effects of Rifalin I 450 mg/300 mg Tablet

When taking Rifalin I 450 mg/300 mg Tablet, you may experience side effects that typically improve as your body gets used to the medication. However, if they persist or cause concern, it's important to consult your doctor. Some common side effects include dark colored urine, rash, vomiting, jaundice, fever, increased liver enzymes, nausea, and peripheral neuropathy, which can cause tingling and numbness in the feet and hands.


Safety advice

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liver

When taking Rifalin I 450 mg/300 mg Tablet, it is essential to exercise caution if you have liver disease. Patients with liver issues may require a dose adjustment, so consulting your doctor before starting this medication is crucial. It is advised not to use Rifalin I 450 mg/300 mg Tablet in cases of severe liver disease. Your doctor can provide specific guidance tailored to your liver health status.

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kidney

Rifalin I 450 mg/300 mg Tablet requires caution in patients with kidney disease. Adjusting the dose may be necessary. Please consult your doctor before using Rifalin I 450 mg/300 mg Tablet.

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alcohol

When using Rifalin I 450 mg/300 mg Tablet, avoid alcohol to prevent symptoms like flushing, rapid heart rate, nausea, chest pain, and low blood pressure. This can cause a Disulfiram reaction.

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driving

Rifalin I 450 mg/300 mg Tablet may cause side effects like fits, mental health problems, and optic neuritis, which could impair your ability to drive. This may affect your driving ability, so caution is advised.

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pregnancy

Rifalin I 450 mg/300 mg Tablet may not be safe to use during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will assess the risks and benefits before prescribing. Please consult your doctor before using.

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breastfeeding

Rifalin I 450 mg/300 mg Tablet can be used safely during breastfeeding. Studies show that it has minimal transfer to breastmilk and is not harmful to the baby.


Consumption warning before consuming Rifalin I 450 mg/300 mg Tablet

Before taking Rifalin I 450 mg/300 mg Tablet, keep in mind that it is a prescription medicine used for treating tuberculosis. Take it exactly as prescribed by your doctor on an empty stomach at a fixed time each day for better results. Avoid exceeding the recommended dose to prevent harmful effects on your body. Completing the full course of treatment is crucial, even if you start feeling better. Abruptly stopping the medication might reduce its effectiveness.

Be aware that common side effects like nausea, vomiting, and fever may occur but can be managed by staying hydrated. Contact your doctor immediately if these side effects worsen or if you experience any allergic reactions. Inform your doctor about any other medications you are taking, especially if you have liver or kidney issues. Pregnant or nursing women should seek medical advice before using this medication.

Refrain from consuming alcohol while on this medication, as it can lead to excessive drowsiness. Although it generally does not impair driving abilities, avoid driving if it causes drowsiness or dizziness. Ensure to rest adequately and maintain a healthy diet during treatment. Your doctor may request lab tests to monitor your body's response to the medicine.


What if you forgot to take Rifalin I 450 mg/300 mg Tablet?

If you forget to take a dose of Rifalin I 450 mg/300 mg Tablet, take it as soon as you remember. But if it is almost time for your next dose, just skip the missed dose and continue with your normal schedule. It's important not to double up on doses to make up for the missed one. Stick to your prescribed dosage regimen to ensure the effectiveness of the medication.


Related lab tests

For monitoring the effects of Rifalin I 450 mg/300 mg Tablet, several related lab tests are recommended. These tests help in assessing the impact of the medication on different aspects of the body. The Complete Blood Count (CBC) test is crucial as it provides information about various blood components including red blood cells, white blood cells, and platelets. Another important test is the Erythrocyte Sedimentation Rate (ESR), which helps in evaluating inflammation in the body. Mycobacterium Tuberculosis DNA PCR - Qualitative test is essential for detecting the presence of tuberculosis DNA, especially if the patient is at risk of tuberculosis. Additionally, a Peripheral Smear Examination may be recommended to assess the appearance of blood cells under a microscope. These related lab tests can provide valuable insights into the patient's health status while on Rifalin I 450 mg/300 mg Tablet.


Additional Information

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 11-Feb-2025