Recovorin 50mg Injection

By Recovorin

Rx

5ml Injection in a Vial

Composition icon

Composition

Calcium Leucovorin(50mg)

Manufacturer - Zydus Cadila icon

Manufacturer - Zydus Cadila

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after icon

Expires on or after

July, 2026

About Recovorin 50mg Injection

Recovorin 50mg Injection, a medication belonging to the class of folic acid analogues, is primarily utilized to counteract the detrimental effects of methotrexate overdose, a powerful anticancer drug. Methotrexate is commonly employed in the treatment of cancer, severe rheumatoid arthritis, and severe psoriasis. However, it can sometimes lead to serious side effects such as vision loss, seizures, and loss of consciousness. Recovorin 50mg Injection is also prescribed for the treatment of anemia caused by low folic acid levels in the body, as well as for colorectal cancer when used with the chemotherapy drug 5-fluorouracil.

The active ingredient in Recovorin 50mg Injection is leucovorin, a type of vitamin B known for its role in preventing healthy cells from the toxic effects of methotrexate while allowing it to target and eliminate cancer cells effectively. This medication should be administered promptly following methotrexate intake to maximize its beneficial effects. Recovorin 50mg Injection is typically administered by a healthcare professional in a clinical setting, as it involves a slow injection into the veins to ensure proper supervision and safe application.

Patients undergoing treatment with Recovorin 50mg Injection may encounter common side effects such as injection site reactions (pain, swelling, redness), infections, nausea, vomiting, diarrhea, and constipation. While most of these side effects are temporary and do not necessitate medical intervention, persistent or severe symptoms should be promptly reported to the healthcare provider.

Before initiating treatment with Recovorin 50mg Injection, it is crucial to inform the doctor about any allergic reactions to medications or foods, as well as your medical history and current medications. Special attention should be given to disclosing pregnancy, plans for pregnancy, breastfeeding, anemia, GI toxicity, renal impairment, and seizure disorders to ensure the safe and effective use of this medication. Regular monitoring and communication with healthcare professionals are essential for optimizing the benefits of Recovorin 50mg Injection and minimizing the risk of adverse effects.


Benefits

Recovorin 50mg Injection offers valuable benefits in preventing the harmful effects of methotrexate, a potent anti-cancer medication. By safeguarding the body cells against the detrimental impacts of methotrexate, this injection plays a crucial role in ensuring the optimal effectiveness of the anti-cancer treatment. Administered 24 hours after methotrexate, Recovorin 50mg Injection acts as a form of vitamin B that helps in enhancing the anti-cancer effects of methotrexate. Additionally, it serves as a protective shield against potential side effects like anemia, thus promoting a more favorable overall treatment outcome. By incorporating Recovorin 50mg Injection into cancer therapy regimens, patients can benefit from enhanced protection against the adverse effects of methotrexate, ultimately improving their quality of life during treatment.


How to use the Recovorin 50mg Injection

When it comes to using Recovorin 50mg Injection, it is important to always rely on the guidance of your doctor or nurse. This medication should never be taken by yourself. Your healthcare provider will administer the injection to you, so it is crucial to follow their instructions carefully. Avoid self-administration and trust the professionals for the safe and proper use of Recovorin 50mg Injection. Remember, your well-being is the top priority, so always consult with your healthcare team for the best and safest practices when using this medication.


Uses of Recovorin 50mg Injection

Recovorin 50mg Injection is used to prevent the harmful effects of methotrexate, a medication commonly prescribed to treat various conditions such as cancer, psoriasis, and rheumatoid arthritis. When methotrexate is used to treat these conditions, it can sometimes lead to side effects that affect the body's normal function. The primary purpose of using Recovorin 50mg Injection is to help mitigate or reduce these adverse effects caused by methotrexate therapy. By incorporating Recovorin 50mg Injection into the treatment plan, healthcare providers aim to support patients in better managing their conditions while minimizing the impact of methotrexate-related complications.


What conditions Recovorin 50mg Injection treats?

Recovorin 50mg Injection is used to protect the body cells from the harmful effects of methotrexate, an anticancer medicine. It is essential in preventing and treating methotrexate overdose. It is administered slowly into the veins under doctor's supervision. The dosage and frequency will be determined by your doctor based on your condition. Common side effects include pain, swelling, and redness at the injection site. Regular blood tests are needed to monitor cell counts and methotrexate levels. Inform your doctor about any existing health conditions or medications.


Should you consult a doctor?

If you experience injection site reactions such as pain, swelling, or redness that bother you or seem severe, it's important to inform your doctor. Additionally, if you have seizures, liver, or kidney issues, or if you are taking medications for infections, consult your healthcare provider before starting Recovorin 50mg Injection. Since various medicines can interact with this injection, including phenytoin for seizures, it is crucial to disclose all your current medications to your healthcare team. If you are pregnant or breastfeeding, it's essential to discuss this with your doctor before using this medicine. Regular blood tests are necessary to monitor your blood cells and serum methotrexate levels. Remember to take Recovorin 50mg Injection exactly as prescribed to avoid serious side effects. If you notice persistent side effects or are concerned about any symptoms, seek medical advice promptly.


Side effects of Recovorin 50mg Injection

When using Recovorin 50mg Injection, you may experience side effects, although most of them do not typically need medical attention and tend to fade as your body gets used to the medication. However, it is essential to consult your doctor if the side effects persist or if you have concerns about them. Some common side effects associated with Recovorin 50mg Injection include injection site reactions such as pain, swelling, and redness. If you notice any of these effects, it is advisable to inform your healthcare provider for further guidance.


Safety advice

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liver

Caution is advised when using Recovorin 50mg Injection in patients with liver disease. Limited information is available regarding its use in such cases. It is important to consult with your doctor before using this medication to ensure its safety and effectiveness for individuals with liver issues.

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kidney

Limited information available on Recovorin 50mg Injection use in patients with kidney disease. Consult doctor for guidance.

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alcohol

Consult your doctor when consuming alcohol with Recovorin 50mg Injection.

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driving

"When using Recovorin 50mg Injection, your ability to drive is typically unaffected."

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pregnancy

Recovorin 50mg Injection may not be safe to use during pregnancy. Limited human studies suggest potential harm to the developing baby. Your doctor will assess the benefits and risks before prescribing. Please consult your doctor regarding this.

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breastfeeding

Information about using Recovorin 50mg Injection during breastfeeding is not provided. Therefore, it is advised to consult your doctor regarding its safety during breastfeeding.


Consumption warning before consuming Recovorin 50mg Injection

Before taking Recovorin 50mg Injection, it is important to be aware of some precautions. This injection is primarily used to counteract the harmful effects of methotrexate and to treat methotrexate overdose. It should only be administered as a slow injection into the veins under the supervision of a doctor. Your doctor will determine the appropriate dosage and frequency based on your condition, so it is crucial to follow their instructions precisely. Taking the medication improperly or in excessive amounts can lead to severe side effects.


Common side effects of Recovorin 50mg Injection include reactions at the injection site such as pain, swelling, and redness. If these symptoms become bothersome or worsen, inform your doctor promptly. Regular blood tests are necessary to monitor your blood cells and the concentration of methotrexate in your bloodstream.


Before beginning treatment with this injection, ensure your doctor is aware of any history of seizures, liver or kidney issues, or if you are taking medications for infections. It is important to disclose all medications you are currently using, particularly phenytoin for seizures, as interactions can occur. Pregnant or breastfeeding individuals should also inform their doctor to ensure the safety of taking this medication.


What if you forgot to take Recovorin 50mg Injection?

If you forget to take your scheduled dose of Recovorin 50mg Injection, try to take it as soon as you remember. But if it's almost time for your next dose, it's best to skip the missed one and continue with your usual dosing schedule. Avoid taking a double dose to make up for the missed one. It is important to follow the prescribed dosing instructions to maintain the effectiveness of the medication.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic Class-
Action ClassCytoprotective agents- methotrexate

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 01-Oct-2024