Rafinlar 75mg Capsule

By Rafinlar

Rx

28 Capsule in a Bottle

Composition icon

Composition

Dabrafenib(75mg)

Manufacturer - Novartis India Ltd icon

Manufacturer - Novartis India Ltd

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Expires on or after icon

Expires on or after

July, 2026

About Rafinlar 75mg Capsule

Rafinlar 75mg Capsule is an anti-cancer medication used in the treatment of malignant melanoma, a type of skin cancer that arises from the abnormal growth of cells dividing uncontrollably. This medicine is specifically designed for patients with unresectable or metastatic melanoma who have a specific genetic mutation known as BRAF V600E or V600K. Additionally, Rafinlar 75mg Capsule may be prescribed alongside trametinib for treating other types of cancers such as anaplastic thyroid cancer, non-small cell lung cancer with BRAF V600E mutation, and solid tumors with BRAF V600E mutation.

The active ingredient in Rafinlar 75mg Capsule, Dabrafenib, falls under the class of kinase inhibitors. Its mechanism of action involves inhibiting the activity of an enzyme called tyrosine kinase, which plays a vital role in halting the abnormal proliferation of cancer cells within the body.

Patients taking Rafinlar 75mg Capsule are advised to adhere to the dosage instructions provided by their healthcare provider. It is recommended to consume the capsule at least one hour before or two hours after a meal. The treatment duration varies depending on individual response to the medication, and regular eye examinations may be recommended by the doctor during the course of treatment.

While Rafinlar 75mg Capsule exhibits significant therapeutic benefits, it may also present certain side effects. Common adverse reactions to this medication include diarrhea, nausea, fever, and headache. Should these side effects persist or worsen, it is essential to inform your doctor promptly. Furthermore, Rafinlar 75mg Capsule is a potent medication that could potentially lead to severe side effects impacting the body's ability to combat infections, as well as affecting blood, liver, or kidney functions. Patients should be vigilant and report any unusual symptoms like bleeding, fatigue, loss of appetite, or changes in vision to their healthcare provider immediately.

Prior to initiating treatment with Rafinlar 75mg Capsule, it is crucial to disclose any pre-existing liver or kidney conditions, as well as inform your doctor about any ongoing medication for infections. Due to potential interactions with other drugs, it is paramount to provide a comprehensive list of all medications being used. Notably, this medication is contraindicated during pregnancy and lactation, emphasizing the importance of employing effective contraception methods for both males and females to prevent unintended pregnancies during the treatment period.


Benefits

Rafinlar 75mg Capsule is beneficial in the treatment of malignant melanoma, a dangerous form of skin cancer that originates in melanocytes, the cells responsible for producing melanin pigment. Melanin is the pigment that gives color to the skin. Malignant melanoma is known to be one of the most lethal and aggressive types of skin cancer. This medication functions by targeting the genetic code within the cancer cells, which is referred to as DNA, leading to their destruction. By doing so, Rafinlar 75mg Capsule not only eliminates the cancer cells but also hinders their growth and prevents further spreading, thereby aiding in the treatment of cancer.

Containing Dabrafenib, Rafinlar 75mg Capsule is effective in treating various types of cancer by inhibiting the action of a tyrosine kinase enzyme responsible for the proliferation of cancerous cells. Through this mechanism, the medication halts the abnormal growth of cancer cells, consequently impeding their spread to other parts of the body. Additionally, Rafinlar 75mg Capsule reduces the blood supply to cancerous tumors, thereby slowing down their growth. Consequently, the drug plays a crucial role in impeding the production, spread, and growth of cancer cells within the body, demonstrating its immense therapeutic benefits in the treatment of malignant melanoma and other forms of cancer.


How to use the Rafinlar 75mg Capsule

To use Rafinlar 75mg Capsule properly, follow these guidelines provided by your doctor. Take this medication on an empty stomach, either at least one hour before or 2 hours after meals, as directed. Swallow the capsule whole with a glass of water; do not crush, break, or chew it. Your doctor may recommend taking Rafinlar 75mg Capsule 28's twice daily with a 12-hour interval between doses. Make sure not to exceed the prescribed dosage. Consulting your doctor about any questions or concerns regarding the usage of this medication is crucial for its effectiveness and safety.


Uses of Rafinlar 75mg Capsule

'Rafinlar 75mg Capsule' is primarily used in the treatment of several types of cancer. It is commonly prescribed for the treatment of Malignant melanoma, which is a serious type of skin cancer. Additionally, this medication is also used to treat Metastatic melanoma, Anaplastic thyroid cancer, Non-small cell lung cancer, and Metastatic solid tumors. These conditions are all aggressive forms of cancer where Rafinlar 75mg Capsule plays a crucial role in managing the disease and reducing its progression. This medication is recommended by healthcare providers as part of a comprehensive treatment plan for patients diagnosed with these types of cancers.


What conditions Rafinlar 75mg Capsule treats?

Rafinlar 75mg Capsule is used for treating metastatic malignant melanoma, which is a type of skin cancer affecting melanocytes due to exposure to harmful UV radiation. In non-small cell lung cancer (NSCLC), the capsule is used with different chemotherapy combinations for treatment. Anaplastic thyroid cancer occurs when abnormal cells grow in the thyroid gland. Rafinlar 75mg Capsule is not indicated for this condition.


Should you consult a doctor?

If you experience any unusual symptoms while taking Rafinlar 75mg Capsule, it is important to seek medical attention promptly. Notify your doctor if you notice any eye irritation, blurred vision, eye pain, or other changes in your vision. Additionally, inform your healthcare provider if common side effects like diarrhea, fever, nausea, or headache persist or worsen.

Seek immediate medical assistance if you observe unusual bleeding or bruising, lack of energy, loss of appetite, or yellowing of the eyes, as these may indicate serious health issues affecting your blood, liver, or kidneys. Also, consult your doctor if you have concerns about how the medication is affecting you, especially if you have liver or kidney problems or if you are taking other medications.

Remember that Rafinlar 75mg Capsule is a potent treatment for malignant melanoma and can impact your body's ability to fight infections. Regular monitoring by your doctor, including blood tests, is essential to ensure your well-being and safety throughout the course of treatment. If you are uncertain or worried about any symptoms or side effects, do not hesitate to seek guidance from your healthcare provider.


Side effects of Rafinlar 75mg Capsule

Side Effects:

When taking Rafinlar 75mg Capsule, some individuals may experience side effects. Most of these side effects are not severe and tend to subside as your body gets used to the medication. However, if any of these side effects persist or if you become concerned about them, it is important to consult your doctor.

Common side effects of Rafinlar 75mg Capsule can include diarrhea, fever, nausea, chills, headache, joint pain, cough, muscle pain, and swelling. Other potential side effects to watch for are vomiting, loss of appetite, tiredness, dizziness, weakness, warts, itching, rash, abdominal pain, vision problems, increased blood pressure, acne, and infection around finger and toenails.

It is essential to be aware of these possible side effects and to seek medical advice if you experience any persistent or worrying symptoms while taking Rafinlar 75mg Capsule. Your doctor can provide guidance on managing these side effects and may recommend adjustments to your treatment if needed.


Safety advice

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liver

When it comes to safety advice for the liver concerning the use of Rafinlar 75mg Capsule, it is considered safe for patients with liver disease. There is no need for a dose adjustment of this medication in such cases. However, it is essential to inform your doctor if you have a pre-existing liver condition or a history of liver problems before beginning treatment with Rafinlar 75mg Capsule. This information will allow your healthcare provider to determine the best course of action tailored to your specific needs.

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kidney

Rafinlar 75mg Capsule is safe for patients with kidney disease, no dose adjustment is needed. Inform your doctor if you have kidney issues before taking.

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alcohol

Consult your doctor when consuming alcohol with Rafinlar 75mg Capsule.

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driving

When taking Rafinlar 75mg Capsule, be cautious while driving as it may cause visual disturbances like blurred or loss of vision in some patients. Refrain from driving or operating machinery until you are fully alert.

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pregnancy

Rafinlar 75mg Capsule should not be used during pregnancy due to potential harm to the developing baby based on animal studies. Consult your doctor before taking this medication, especially if you are pregnant or planning to become pregnant. Effective birth control methods should be used during treatment with Rafinlar 75mg Capsule.

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breastfeeding

Rafinlar 75mg Capsule may not be safe for breastfeeding as it can potentially pass into breastmilk and harm the baby. It is advisable to inform your doctor if you plan to breastfeed. Avoid breastfeeding while taking Rafinlar 75mg Capsule and for at least two weeks after the final dose.


Consumption warning before consuming Rafinlar 75mg Capsule

Before consuming Rafinlar 75mg Capsule 28's, it is crucial to follow your doctor's prescribed duration of treatment. Do not take this medication if you have allergies to its components. Use caution if you have a history of liver or kidney disease, heart issues, blood disorders, diabetes, eye problems, or gastrointestinal complications. It is vital to inform your doctor if you are pregnant or planning to conceive, as Rafinlar can harm the fetus. Breastfeeding should be avoided during treatment due to potential risks to the infant from the medication passing into breast milk. Refrain from driving or operating machinery as visual disturbances may occur. This medicine is not for children under six years old. Rafinlar may lead to various adverse effects such as hypertension, cardiovascular events, and skin reactions, among others. Disclose your full medical history to your doctor before initiating Rafinlar 75mg Capsule 28's treatment.


Additional Information

Habit FormingNo
Chemical ClassSulfanilide Derivative
Therapeutic Class-
Action Class-

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Preeti Kumar

MBBS, DGO - Obstetrics and Gynaecology, DNB - Obstetrics and Gynaecology

Last update on 11-Feb-2025