Progivian 8% Vaginal gel

By Progivian

Rx

1gm Vaginal gel in a Tube

Composition icon

Composition

Progesterone(8% w/w)

Manufacturer - Nivian Pharma LLP icon

Manufacturer - Nivian Pharma LLP

3rd Floor, Prabhu Vijay, V M Road, Vile Parle West Mumbai Mumbai City MH 400056 IN

Expires on or after icon

Expires on or after

May, 2026

About Progivian 8% Vaginal gel

Progivian 8% Vaginal gel is a medication belonging to the hormonal class, specifically designed to address female infertility and support pregnancy. It is also utilized to reestablish the menstrual cycle in women experiencing irregular periods or a complete absence of menstruation. Female infertility refers to the inability to conceive despite consistent unprotected sexual intercourse for a year or more.

The key component of Progivian 8% Vaginal gel is progesterone, an essential female hormone crucial for regulating ovulation and menstrual cycles in women. By inducing secretory changes in the endometrium lining of the uterus, relaxing the uterus, inhibiting the maturation and release of follicles, and supporting the maintenance of pregnancy, this gel plays a vital role in addressing infertility issues and menstrual irregularities.

When using Progivian 8% Vaginal gel, it is imperative to strictly follow your doctor's instructions. This medication is intended for intra-vaginal use only, and it is crucial not to exceed or reduce the prescribed dosage without medical guidance. In some instances, common side effects like abdominal pain, headache, constipation, nausea, and breast pain or enlargement may occur. Usually, these side effects subside over time and do not require immediate medical attention. However, if these effects persist, it is advisable to consult your healthcare provider promptly.

Before commencing the use of Progivian 8% Vaginal gel, inform your doctor about any existing or past liver or kidney problems, heart conditions, diabetes, asthma, epilepsy, migraine, or depression. It is essential to disclose if you are pregnant or breastfeeding, as well as provide a comprehensive list of all medications you are currently taking to prevent potential adverse reactions or interactions. Additionally, avoiding smoking and alcohol consumption is recommended while using this medication to ensure optimal efficacy and safety.


Benefits

Progivian 8% Vaginal gel offers significant benefits to women in two key areas: hormone replacement therapy and female infertility. In hormone replacement therapy, this gel is a valuable treatment for alleviating various symptoms of menopause, including hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. By containing progesterone, an important hormone along with estrogen, Progivian 8% Vaginal gel helps in restoring hormonal balance and boosting overall quality of life during the menopausal stage, which can extend for several years. It not only addresses these uncomfortable symptoms but also has a positive impact on daily life and mood. The ease of application through vaginal tablets and gels adds to its convenience, although it's essential to strictly follow the prescribed usage and duration recommended by a healthcare provider.

In female infertility, Progivian 8% Vaginal gel plays a crucial role in regulating ovulation and menstruation by supplying progesterone, a key female hormone. Specifically designed for women who are not experiencing periods due to a deficiency in natural progesterone, this gel helps induce menstrual cycles and prepare the uterus for a potential pregnancy. By thickening the uterus lining (endometrium), Progivian 8% Vaginal gel enhances the chances of successful conception and pregnancy. The gel's ability to bring about secretory changes in the uterine endometrium, relax the uterus, prevent follicle maturation, and support pregnancy maintenance further highlights its effectiveness in assisting women with fertility issues. It's imperative to adhere to the prescribed treatment regimen for optimal outcomes, which may entail continuing with the gel even after pregnancy is achieved.

Overall, Progivian 8% Vaginal gel's combination of progesterone benefits women by addressing menopausal symptoms and aiding in fertility enhancement, making it a valuable treatment option under medical supervision.


How to use the Progivian 8% Vaginal gel

To use Progivian 8% Vaginal gel, start by checking the label for directions provided by your doctor. Ensure the affected area is clean and dry before application. Then, insert the gel into the vagina using the included applicator as instructed. Wash your hands after applying the gel to maintain hygiene. For the vaginal spray variant, shake it well before each use and spray the contents from a distance of 5cm onto the affected area. Remember to follow the dosage and duration recommended by your healthcare provider for the best results.


Uses of Progivian 8% Vaginal gel

Progivian 8% Vaginal gel is used in hormone replacement therapy specifically for female infertility. It helps address hormonal imbalances and enhances fertility. The gel is designed for vaginal application and provides a targeted delivery of hormones to support the reproductive system. By using Progivian 8% Vaginal gel, women experiencing infertility issues can potentially improve their chances of conception by balancing their hormone levels effectively.


What conditions Progivian 8% Vaginal gel treats?

"Progivian 8% Vaginal gel" is indicated for the treatment of female infertility, a condition where a woman is unable to conceive after a year of trying. It can also help in cases where a woman experiences miscarriages or stillbirths, which are also considered forms of infertility.


Should you consult a doctor?

Seek medical help if you experience severe allergic reactions like difficulty breathing, swelling of the face, lips, throat, hives, or rash after using Progivian 8% Vaginal gel. Inform your doctor if you have a history of breast cancer, abnormal vaginal bleeding, or liver disease. Monitor and report any persistent side effects such as headache, abdominal pain, or breast tenderness to your healthcare provider. If you notice symptoms like fatigue, joint pain, or abnormal menstrual bleeding, consult your doctor promptly. Additionally, seek medical attention if you have unusual symptoms like slurred speech, pain behind the eyes, or vertigo while using this medication. Always keep your doctor informed about your medical history and other medications you are taking to ensure safe and effective treatment.


Side effects of Progivian 8% Vaginal gel

Potential side effects of Progivian 8% Vaginal gel may include headache, fatigue, joint pain, cough, abnormal menstrual bleeding, musculoskeletal pain (related to bones, muscles, or joints), slurred speech, pain behind the eyes, and vertigo. Some individuals may also experience abdominal pain, constipation, nausea, and breast pain or enlargement. It is important to note that most side effects are temporary and may subside as your body gets used to the medication. However, if any side effects persist or cause concern, it is advisable to consult with your doctor for further guidance and support.


Safety advice

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liver

For the safety of your liver, it is important to be cautious when using Progivian 8% Vaginal gel. If you have a history of liver disease or have experienced abnormal liver test results in the past, it is advised not to use this product. There is no established interaction between Progivian 8% Vaginal gel and liver issues, but it is better to err on the side of caution. It is recommended to consult with your doctor before using this gel if you have concerns about your liver health.

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kidney

No interaction found/established. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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alcohol

When using Progivian 8% Vaginal gel, it is uncertain if alcohol impacts its effectiveness. To be safe, it is recommended to avoid or reduce alcohol consumption while using the gel.

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driving

Progivian 8% Vaginal gel does not affect driving or machine operation.

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pregnancy

Progivian 8% Vaginal gel appears to be safe for use during pregnancy, with studies indicating minimal risk to the baby. It is advisable to consult your doctor prior to using the gel. The doctor will assess the pregnant woman's condition to determine if it is suitable for her.

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breastfeeding

Progivian 8% Vaginal gel is considered safe for use while breastfeeding. Studies show minimal transfer to breastmilk posing no harm to the baby.


Consumption warning before consuming Progivian 8% Vaginal gel

Before using Progivian 8% Vaginal gel, please note the following warnings. Avoid if allergic to any ingredients or experiencing unexplained vaginal bleeding, porphyria, cancer, thrombophlebitis, missed abortion, or miscarriage. Inform your doctor about your health status and medications to rule out any potential side effects or interactions. This product is not suitable for children.


Disease interactions

Progivian 8% Vaginal gel can interact with various disease conditions, impacting how the medication works in the body. People with porphyria, a rare blood disorder, should be cautious when using Progivian 8% Vaginal gel, as it may affect their condition. Additionally, individuals with a history of breast or genital cancer should consult their healthcare provider before using this gel, as it could potentially interfere with their treatment or recovery process.
Moreover, those experiencing abnormal vaginal bleeding due to reasons like miscarriage or missed abortion should be mindful of using Progivian 8% Vaginal gel, as it could exacerbate this issue. People with a history of blood clots or stroke need to seek medical advice before using this gel, as it might pose risks or complications for them.
Furthermore, individuals with liver disease or abnormal liver tests should exercise caution when considering Progivian 8% Vaginal gel, as it could impact their liver function or overall health. It is crucial for patients with any of these conditions to have a thorough discussion with their healthcare provider before starting treatment with Progivian 8% Vaginal gel to ensure safe and effective use.


Related lab tests

In order to monitor the effects of Progivian 8% Vaginal gel, several related lab tests may be recommended by healthcare professionals. These tests can provide valuable information about how the medication is impacting various aspects of the body. The Anti Mullerian Hormone (AMH) test is important for assessing ovarian reserve in women and can help determine fertility status. Glycosylated Hemoglobin (HbA1c) test is used to monitor blood sugar control over time, which is essential for individuals with diabetes. Testosterone Total test measures the total amount of testosterone in the blood and can be helpful in evaluating hormonal balance. Thyroid Stimulating Hormone (TSH) test checks the function of the thyroid gland and can detect conditions like hypothyroidism or hyperthyroidism. These lab tests are commonly used to assess different aspects of overall health and may be recommended alongside the use of Progivian 8% Vaginal gel to ensure proper monitoring and management of any potential effects.


Additional Information

Habit FormingNo
Chemical ClassProgesterone Derivative
Therapeutic ClassGYNAECOLOGICAL
Action ClassNatural Progesterone

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 11-Feb-2025