Pirfeza 400mg Tablet
By Pirfeza
Rx
10 Tablet in a Strip

Composition
Pirfenidone(400mg)

Manufacturer - Uniza Healthcare LLP
C-401, Ganesh Meridian, Opp. Gujarat High Court, Sarkhej - Gandhinagar Hwy, Sola, Ahmedabad, Gujarat 380060

Expires on or after
September, 2025
About Pirfeza 400mg Tablet
Pirfeza 400mg Tablet is a prescription medicine used for treating idiopathic pulmonary fibrosis, a condition that causes scarring and swelling in the lungs, making it difficult to breathe. Taking this tablet helps to reduce the scarring and swelling, thereby improving breathing. It is important to take Pirfeza 400mg Tablet with food for best results. Remember to take it at the same time each day as prescribed by your doctor. The dosage and frequency of intake will be determined by your doctor based on your condition, so follow their instructions carefully. It is essential to continue taking the medicine for the duration prescribed to fully benefit from its effects.
Potential Side Effects:
Common side effects of Pirfeza 400mg Tablet may include insomnia, headache, dizziness, dyspepsia, nausea, diarrhea, and photosensitivity. If you experience dizziness, it is advisable to avoid activities that require focus, such as driving. Some individuals may also notice weight loss or other side effects, so it's important to monitor your weight regularly and consult your doctor if needed. Your doctor may conduct regular liver function tests while you are on this medication to ensure its safety and effectiveness.
Precautions and Considerations:
Prior to taking Pirfeza 400mg Tablet, inform your doctor if you have liver or kidney disease. It's crucial to disclose all other medications you are currently taking, as some may interact with Pirfeza and affect its efficacy. Since this medicine can make your skin sensitive to sunlight, it is recommended to wear protective clothing and use sunscreen when exposed to direct sunlight. Additionally, if you are pregnant or breastfeeding, make sure to consult your doctor before starting this medication to ensure the safety of both you and your baby.
Benefits
Pirfeza 400mg Tablet is a valuable medication specifically designed to address the symptoms of idiopathic pulmonary fibrosis (IPF), a condition wherein the lung tissue becomes thick and stiff, leading to the formation of scar tissue within the lungs. This scarring, known as fibrosis, develops due to a continuous cycle of lung damage and subsequent healing. The irreversible changes associated with IPF can manifest as initial symptoms like shortness of breath or dry cough.
By targeting the root cause of the disease, Pirfeza 400mg Tablet effectively works to reduce the scarring and fibrosis in the lungs. As a result, breathing becomes noticeably easier for individuals suffering from IPF. Clinical studies have shown that Pirfeza 400mg Tablet can significantly slow down the rate of decline in lung function by up to 50%. The mechanism of action involves decreasing the release and activity of naturally occurring growth factors in the body, which in turn helps to alleviate scarring and swelling in the lungs, ultimately improving the overall respiratory function.
Additionally, Pirfeza 400mg Tablet plays a crucial role in slowing down the progression of idiopathic pulmonary fibrosis, offering patients the opportunity to manage their condition more effectively and potentially enhance their quality of life. It is important to note that while using Pirfeza 400mg Tablet, some individuals may experience certain side effects. In such cases, it is highly recommended to have an open discussion with a healthcare provider to address any concerns or uncertainties.
In summary, Pirfeza 400mg Tablet emerges as a beneficial anti-fibrotic medication for adults dealing with idiopathic pulmonary fibrosis, offering the potential to mitigate the impact of the disease and promote better respiratory health.
How to use the Pirfeza 400mg Tablet
To use Pirfeza 400mg Tablet, follow the instructions provided by your doctor. It is important to take this medication in the dose and duration recommended by your healthcare provider. Swallow the tablet whole with a glass of water, preferably with food to avoid any potential stomach upset. Do not chew, crush, or break the tablet before swallowing it. Your physician will determine the appropriate dosage and duration based on factors such as your age, body weight, and the specific condition being treated. It is essential to adhere to your doctor's instructions carefully to ensure the medication is effective and to minimize the risk of side effects. If you have any questions or concerns about using Pirfeza 400mg Tablet, consult your doctor for further guidance.
Uses of Pirfeza 400mg Tablet
Pirfeza 400mg Tablet is used for the treatment of idiopathic pulmonary fibrosis (IPF), a condition that causes progressive scarring in the lungs, leading to difficulty in breathing and reduced lung function. This medication is specifically designed to target and manage the symptoms associated with IPF. It is a valuable option for individuals suffering from this debilitating respiratory disease, as it helps to slow down the progression of fibrosis in the lungs and improve overall lung function. By following the prescribed dosage and recommendations from a healthcare professional, Pirfeza 400mg Tablet can effectively help in managing the symptoms and improving the quality of life for patients with idiopathic pulmonary fibrosis.
What conditions Pirfeza 400mg Tablet treats?
Idiopathic pulmonary fibrosis (IPF) is part of a group of lung diseases where the lung tissues become inflamed and scarred. Over time, this scarring, or fibrosis, thickens and stiffens, making it difficult for the lungs to function well. This can result in decreased lung function, leading to breathlessness and coughing. Symptoms of IPF include shortness of breath, persistent dry cough, loss of appetite, weight loss, and changes in the fingers and toes. These breathing difficulties can cause other health issues.
Should you consult a doctor?
If you experience severe photosensitive reactions to sunlight, such as increased sensitivity or skin rashes, it is advisable to consult your doctor while taking Pirfeza 400mg Tablet. Additionally, smokers should seek medical advice before starting this medication. It is essential to seek a doctor's guidance if you encounter any unusual symptoms or side effects while on Pirfenex 400mg to ensure proper management. Your doctor can assess your condition and recommend appropriate measures to address any concerns related to the medication.
Side effects of Pirfeza 400mg Tablet
When taking Pirfeza 400mg Tablet, you may experience a range of side effects. Common side effects that may occur and usually subside as your body gets used to the medication include insomnia, headache, dizziness, tiredness, sinus inflammation, loss of appetite, upper respiratory tract infection, weight loss, nausea, indigestion, diarrhea, and photosensitivity. It is important to consult your doctor if these side effects persist or if you have concerns about them.
In some cases, more severe side effects may occur, and you should stop taking Pirfeza 400mg Tablet and contact your doctor immediately if you experience any of the following: signs of angioedema or serious allergic reactions such as urticaria, itching, swelling of the face, lips, tongue, or throat causing difficulty in breathing or feeling faint; signs of abnormal liver function like yellowish discoloration of the skin, dark urine, itching, pain on the upper right side of the abdomen, loss of appetite, bleeding or bruising more easily, and tiredness; signs and symptoms of Stevens-Johnson syndrome or toxic epidermal necrolysis, including fever, flu-like symptoms, reddish or circular patches on the trunk with central blisters, peeling of the skin, and ulcers on the mouth, throat, eyes, nose, and genitals.
Other potential side effects may include infections of the throat or airways, sinusitis, influenza, common cold, stomach problems like acid reflux, vomiting, constipation, and stomach upset, decreased appetite, difficulty sleeping, shortness of breath, joint pain, bladder infections, changes in taste sensation, hot flushes, bloating, abdominal pain, heartburn, flatulence, elevated liver enzymes, sunburn or skin reactions from sun exposure, skin problems like rashes, itchy skin, redness, dry skin, muscle pain, weakness, chest pain, and feeling low on energy. If you experience any of these severe side effects, prompt medical attention is necessary.
Safety advice

liver
When using Pirfeza 400mg Tablet, it's important to be cautious if you have liver disease. Patients with liver issues may require adjustments in the dosage of Pirfeza 400mg Tablet, so consulting your doctor before using this medication is crucial. It is not advisable to use Pirfeza 400mg Tablet in individuals with severe liver disease. Protect your liver health by seeking medical advice before starting treatment with Pirfeza 400mg Tablet.

kidney
Pirfeza 400mg Tablet needs caution in patients with kidney disease. Adjustment of dosage may be necessary. Avoid in severe kidney disease and dialysis patients. Consult your doctor.

alcohol
Consult your doctor when consuming alcohol with Pirfeza 400mg Tablet.

driving
Pirfeza 400mg Tablet can reduce alertness, impact vision, or cause drowsiness and dizziness. If these effects occur, avoid driving.

pregnancy
Pirfeza 400mg Tablet may not be safe during pregnancy as animal studies suggest potential harm to the baby. Consult your doctor for a thorough evaluation before using.

breastfeeding
It is better to consult your doctor before using Pirfeza 400mg Tablet during breastfeeding.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Pirfeza 400mg Tablet
Before taking Pirfeza 400mg Tablet 15's, do not use it if you are allergic to any of its components, have severe liver impairment or kidney disease requiring dialysis, or are taking fluvoxamine. Inform your doctor if you have conditions like photosensitivity, smoke, or have kidney/liver problems. Prior to use during pregnancy or breastfeeding, consult your doctor. Be cautious as Pirfeza 400mg Tablet 15's may cause tiredness and dizziness, affecting your ability to drive. Avoid alcohol consumption with this medication as it may increase dizziness. Not recommended for children under 18 years due to lack of established safety and effectiveness.
Disease interactions
When taking Pirfeza 400mg Tablet, it's crucial to inform your doctor if you have severe liver (hepatic) issues or if you are at an advanced stage of kidney (renal) impairment that requires dialysis. These conditions can impact how your body processes the medication, potentially affecting its effectiveness or causing adverse reactions. By sharing this information with your healthcare provider, they can adjust your treatment plan accordingly to ensure your safety and the best possible outcome.
What happens if you take overdose of Pirfeza 400mg Tablet?
When you take more than the prescribed amount of Pirfeza 400mg Tablet, it is considered an overdose. An overdose can happen if you or someone else accidentally takes too much of the medication. In case of an overdose, it is crucial to seek immediate medical help. Contact your doctor right away or go to the nearest hospital for assistance. It is important to address an overdose promptly to minimize any potential risks or complications.
Related lab tests
For patients taking Pirfeza 400mg Tablet, it is important to monitor their liver health through liver function tests. These tests help to assess the functioning of the liver and detect any potential liver damage or side effects caused by the medication. Some related lab tests that may be recommended for patients on Pirfeza 400mg Tablet include:
1. Liver Enzymes Test (AST, ALT): This test measures the levels of enzymes in the liver that can indicate liver inflammation or damage.
2. Bilirubin Test: Bilirubin is a waste product that the liver processes and excretes. Abnormal levels of bilirubin can suggest liver dysfunction.
3. Albumin Test: Albumin is a protein produced by the liver, and low levels may indicate liver disease or damage.
4. Prothrombin Time (PT) Test: This test measures how long it takes for blood to clot and can be affected by liver function.
Regular monitoring of these lab tests can help healthcare providers ensure the liver is functioning properly and detect any issues early on. It is important for patients to follow their healthcare provider's recommendations for monitoring liver function while taking Pirfeza 400mg Tablet.
Additional Information
Habit Forming | No |
Chemical Class | Pyridones Derivative |
Therapeutic Class | - |
Action Class | Idiopathic pulmonary fibrosis (IPF) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹380
Inclusive of all taxes
Content verified by

Dr. Upasana Bhatia
MBBS - General Medicine
Last update on 11-Feb-2025