Pirfemac 400 Tablet
By Pirfemac
Rx
10 Tablet in a Strip

Composition
Pirfenidone(400mg)

Manufacturer - Macleods Pharmaceuticals Pvt Ltd
Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Expires on or after
August, 2025
About Pirfemac 400 Tablet
Pirfemac 400 Tablet 10's is a prescription medication designed to treat idiopathic pulmonary fibrosis (IPF) in adults, a condition characterized by irreversible lung damage leading to breathing difficulty. The lungs get scarred and inflamed over time, affecting their proper functioning. The medicine contains Pirfenidone, which works by reducing scarring and swelling in the lungs through the inhibition of natural growth factors' release and activity, ultimately helping to improve breathing.
The primary goal of Pirfemac 400 Tablet 10's is to slow down the progression of idiopathic pulmonary fibrosis. To achieve the maximum benefits from this medication, it is recommended to take it with food consistently at the same time every day. The dosage and frequency will be determined by your doctor based on your specific symptoms and condition. It is crucial to follow the prescribed regimen for the full duration as instructed by your healthcare provider.
While Pirfemac 400 Tablet 10's is generally well-tolerated, some side effects may occur. These can include insomnia, headache, dizziness, dyspepsia, nausea, diarrhea, and photosensitivity. If you experience persistent dizziness, it is advisable to avoid activities requiring alertness, such as driving. Regular monitoring of your weight is recommended, and any significant changes should be reported to your doctor. Additionally, your healthcare provider may conduct periodic liver function tests during your treatment.
Before starting Pirfemac 400 Tablet 10's, inform your doctor about any existing liver or kidney conditions. It is essential to disclose all other medications you are taking to avoid potential interactions that could reduce the effectiveness of this medication. Due to the photosensitivity caused by Pirfemac 400 Tablet 10's, taking precautions such as wearing protective clothing and using sunscreen when exposed to sunlight is advisable. If you are pregnant or breastfeeding, consult with your doctor before using this medication.
It is important to note that Pirfemac 400 Tablet 10's can cause tiredness and dizziness, so caution is advised, especially while driving. Alcohol consumption should be avoided while taking this medication to prevent increased dizziness. This medication is intended for use in adults only, as its safety and effectiveness have not been established for individuals under 18 years old. Communication with your doctor regarding your health status and medication regimen is crucial to ensure optimal outcomes and minimize any potential side effects.
Benefits
Pirfemac 400 Tablet is a valuable medication specifically designed to address the symptoms of idiopathic pulmonary fibrosis (IPF), a condition wherein the lung tissue becomes thick and stiff, leading to the formation of scar tissue within the lungs. This scarring, known as fibrosis, develops due to a continuous cycle of lung damage and subsequent healing. The irreversible changes associated with IPF can manifest as initial symptoms like shortness of breath or dry cough.
By targeting the root cause of the disease, Pirfemac 400 Tablet effectively works to reduce the scarring and fibrosis in the lungs. As a result, breathing becomes noticeably easier for individuals suffering from IPF. Clinical studies have shown that Pirfemac 400 Tablet can significantly slow down the rate of decline in lung function by up to 50%. The mechanism of action involves decreasing the release and activity of naturally occurring growth factors in the body, which in turn helps to alleviate scarring and swelling in the lungs, ultimately improving the overall respiratory function.
Additionally, Pirfemac 400 Tablet plays a crucial role in slowing down the progression of idiopathic pulmonary fibrosis, offering patients the opportunity to manage their condition more effectively and potentially enhance their quality of life. It is important to note that while using Pirfemac 400 Tablet, some individuals may experience certain side effects. In such cases, it is highly recommended to have an open discussion with a healthcare provider to address any concerns or uncertainties.
In summary, Pirfemac 400 Tablet emerges as a beneficial anti-fibrotic medication for adults dealing with idiopathic pulmonary fibrosis, offering the potential to mitigate the impact of the disease and promote better respiratory health.
How to use the Pirfemac 400 Tablet
To use Pirfemac 400 Tablet, follow the instructions provided by your doctor. It is important to take this medication in the dose and duration recommended by your healthcare provider. Swallow the tablet whole with a glass of water, preferably with food to avoid any potential stomach upset. Do not chew, crush, or break the tablet before swallowing it. Your physician will determine the appropriate dosage and duration based on factors such as your age, body weight, and the specific condition being treated. It is essential to adhere to your doctor's instructions carefully to ensure the medication is effective and to minimize the risk of side effects. If you have any questions or concerns about using Pirfemac 400 Tablet, consult your doctor for further guidance.
Uses of Pirfemac 400 Tablet
Pirfemac 400 Tablet is used for the treatment of idiopathic pulmonary fibrosis (IPF), a condition that causes progressive scarring in the lungs, leading to difficulty in breathing and reduced lung function. This medication is specifically designed to target and manage the symptoms associated with IPF. It is a valuable option for individuals suffering from this debilitating respiratory disease, as it helps to slow down the progression of fibrosis in the lungs and improve overall lung function. By following the prescribed dosage and recommendations from a healthcare professional, Pirfemac 400 Tablet can effectively help in managing the symptoms and improving the quality of life for patients with idiopathic pulmonary fibrosis.
What conditions Pirfemac 400 Tablet treats?
Idiopathic pulmonary fibrosis (IPF) is part of a group of lung diseases where the lung tissues become inflamed and scarred. Over time, this scarring, or fibrosis, thickens and stiffens, making it difficult for the lungs to function well. This can result in decreased lung function, leading to breathlessness and coughing. Symptoms of IPF include shortness of breath, persistent dry cough, loss of appetite, weight loss, and changes in the fingers and toes. These breathing difficulties can cause other health issues.
Should you consult a doctor?
If you experience severe photosensitive reactions to sunlight, such as increased sensitivity or skin rashes, it is advisable to consult your doctor while taking Pirfemac 400 Tablet. Additionally, smokers should seek medical advice before starting this medication. It is essential to seek a doctor's guidance if you encounter any unusual symptoms or side effects while on Pirfenex 400mg to ensure proper management. Your doctor can assess your condition and recommend appropriate measures to address any concerns related to the medication.
Side effects of Pirfemac 400 Tablet
When taking Pirfemac 400 Tablet, you may experience a range of side effects. Common side effects that may occur and usually subside as your body gets used to the medication include insomnia, headache, dizziness, tiredness, sinus inflammation, loss of appetite, upper respiratory tract infection, weight loss, nausea, indigestion, diarrhea, and photosensitivity. It is important to consult your doctor if these side effects persist or if you have concerns about them.
In some cases, more severe side effects may occur, and you should stop taking Pirfemac 400 Tablet and contact your doctor immediately if you experience any of the following: signs of angioedema or serious allergic reactions such as urticaria, itching, swelling of the face, lips, tongue, or throat causing difficulty in breathing or feeling faint; signs of abnormal liver function like yellowish discoloration of the skin, dark urine, itching, pain on the upper right side of the abdomen, loss of appetite, bleeding or bruising more easily, and tiredness; signs and symptoms of Stevens-Johnson syndrome or toxic epidermal necrolysis, including fever, flu-like symptoms, reddish or circular patches on the trunk with central blisters, peeling of the skin, and ulcers on the mouth, throat, eyes, nose, and genitals.
Other potential side effects may include infections of the throat or airways, sinusitis, influenza, common cold, stomach problems like acid reflux, vomiting, constipation, and stomach upset, decreased appetite, difficulty sleeping, shortness of breath, joint pain, bladder infections, changes in taste sensation, hot flushes, bloating, abdominal pain, heartburn, flatulence, elevated liver enzymes, sunburn or skin reactions from sun exposure, skin problems like rashes, itchy skin, redness, dry skin, muscle pain, weakness, chest pain, and feeling low on energy. If you experience any of these severe side effects, prompt medical attention is necessary.
Safety advice

liver
When using Pirfemac 400 Tablet, it's important to be cautious if you have liver disease. Patients with liver issues may require adjustments in the dosage of Pirfemac 400 Tablet, so consulting your doctor before using this medication is crucial. It is not advisable to use Pirfemac 400 Tablet in individuals with severe liver disease. Protect your liver health by seeking medical advice before starting treatment with Pirfemac 400 Tablet.

kidney
Pirfemac 400 Tablet needs caution in patients with kidney disease. Adjustment of dosage may be necessary. Avoid in severe kidney disease and dialysis patients. Consult your doctor.

alcohol
Consult your doctor when consuming alcohol with Pirfemac 400 Tablet.

driving
Pirfemac 400 Tablet can reduce alertness, impact vision, or cause drowsiness and dizziness. If these effects occur, avoid driving.

pregnancy
Pirfemac 400 Tablet may not be safe during pregnancy as animal studies suggest potential harm to the baby. Consult your doctor for a thorough evaluation before using.

breastfeeding
It is better to consult your doctor before using Pirfemac 400 Tablet during breastfeeding.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Pirfemac 400 Tablet
Before taking Pirfemac 400 Tablet 15's, do not use it if you are allergic to any of its components, have severe liver impairment or kidney disease requiring dialysis, or are taking fluvoxamine. Inform your doctor if you have conditions like photosensitivity, smoke, or have kidney/liver problems. Prior to use during pregnancy or breastfeeding, consult your doctor. Be cautious as Pirfemac 400 Tablet 15's may cause tiredness and dizziness, affecting your ability to drive. Avoid alcohol consumption with this medication as it may increase dizziness. Not recommended for children under 18 years due to lack of established safety and effectiveness.
Disease interactions
When taking Pirfemac 400 Tablet, it's crucial to inform your doctor if you have severe liver (hepatic) issues or if you are at an advanced stage of kidney (renal) impairment that requires dialysis. These conditions can impact how your body processes the medication, potentially affecting its effectiveness or causing adverse reactions. By sharing this information with your healthcare provider, they can adjust your treatment plan accordingly to ensure your safety and the best possible outcome.
What happens if you take overdose of Pirfemac 400 Tablet?
When you take more than the prescribed amount of Pirfemac 400 Tablet, it is considered an overdose. An overdose can happen if you or someone else accidentally takes too much of the medication. In case of an overdose, it is crucial to seek immediate medical help. Contact your doctor right away or go to the nearest hospital for assistance. It is important to address an overdose promptly to minimize any potential risks or complications.
Related lab tests
For patients taking Pirfemac 400 Tablet, it is important to monitor their liver health through liver function tests. These tests help to assess the functioning of the liver and detect any potential liver damage or side effects caused by the medication. Some related lab tests that may be recommended for patients on Pirfemac 400 Tablet include:
1. Liver Enzymes Test (AST, ALT): This test measures the levels of enzymes in the liver that can indicate liver inflammation or damage.
2. Bilirubin Test: Bilirubin is a waste product that the liver processes and excretes. Abnormal levels of bilirubin can suggest liver dysfunction.
3. Albumin Test: Albumin is a protein produced by the liver, and low levels may indicate liver disease or damage.
4. Prothrombin Time (PT) Test: This test measures how long it takes for blood to clot and can be affected by liver function.
Regular monitoring of these lab tests can help healthcare providers ensure the liver is functioning properly and detect any issues early on. It is important for patients to follow their healthcare provider's recommendations for monitoring liver function while taking Pirfemac 400 Tablet.
Additional Information
Habit Forming | No |
Chemical Class | Pyridones Derivative |
Therapeutic Class | - |
Action Class | Idiopathic pulmonary fibrosis (IPF) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹290
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Content verified by

Dr. Upasana Bhatia
MBBS - General Medicine
Last update on 11-Feb-2025