Pexate 500mg Injection

By Pexate

Rx

1 Powder for Injection in a Vial

Composition icon

Composition

Pemetrexed(500mg)

Manufacturer - Miracalus Pharma Pvt Ltd icon

Manufacturer - Miracalus Pharma Pvt Ltd

213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.

Expires on or after icon

Expires on or after

July, 2026

About Pexate 500mg Injection

Pexate 500mg Injection is a medication used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma. It is administered via injection by a qualified medical professional. The dosage and frequency of administration will be determined by your doctor based on your specific condition, and it is crucial to follow their instructions precisely to avoid serious side effects.

It may take some time, possibly weeks or months, before the benefits of Pexate 500mg Injection become noticeable. It is essential not to discontinue the treatment unless instructed by your doctor. Common side effects of this medication include nausea, vomiting, loss of appetite, and hair loss. Additionally, it may lower the number of blood cells, making the body more susceptible to infections. Therefore, regular blood tests to monitor blood cells, heart function, liver health, and blood uric acid levels are necessary.

Prior to starting treatment with Pexate 500mg Injection, inform your doctor if you have heart disease, liver, or kidney issues, or if you are taking any medications for infections. It's crucial to disclose all medications you are currently using as they may interact with Pexate 500mg Injection. This medication is not recommended during pregnancy or while breastfeeding, and both males and females must use effective contraception during the course of treatment to prevent pregnancy.


Benefits

Pexate 500mg Injection offers multiple benefits for patients dealing with two types of cancer - non-small cell lung cancer and malignant pleural mesothelioma. In cases of non-small cell lung cancer, which is prevalent among both smokers and non-smokers, this medication serves as a powerful tool in combating the disease. It can be administered alone or in conjunction with other medications to enhance its effectiveness. It is important to note that Pexate 500mg Injection is a potent and highly toxic drug, underscoring the necessity of discussing potential risks and advantages with one's healthcare provider before starting treatment. Patients are advised to abstain from alcohol consumption during the course of this treatment and are encouraged to stay well-hydrated by consuming plenty of water.

In the context of malignant pleural mesothelioma, a particularly aggressive form of lung cancer, Pexate 500mg Injection plays a crucial role in the therapeutic regimen. When used in combination with other medications, this injection works by eradicating cancer cells and halting their proliferation. By impeding the spread of cancer cells to other parts of the body, this drug helps contain the disease and improve the patient's prognosis. To derive maximum benefit from this treatment, it is imperative for individuals to adhere closely to their doctor's guidance and promptly seek clarification on any uncertainties that may arise. With its ability to target and combat these challenging forms of cancer, Pexate 500mg Injection stands as a valuable option in the medical arsenal against non-small cell lung cancer and malignant pleural mesothelioma.


How to use the Pexate 500mg Injection

When it comes to using Pexate 500mg Injection, it is important to let your doctor or nurse administer it to you. This medicine should not be self-administered. It will be given to you by a medical professional directly into a vein through an intravenous infusion. Your doctor will determine the right dosage and how long you should receive this treatment based on factors like your age, weight, and the specific condition being treated. Trust your healthcare provider to handle the administration of Pexate 500mg Injection safely and effectively for your well-being.


Uses of Pexate 500mg Injection

Pexate 500mg Injection is used to treat advanced non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma, which is a type of cancer affecting the protective layer of the lungs. This medication is beneficial for patients diagnosed with these specific types of cancer to help alleviate symptoms and potentially slow down the progression of the disease. By targeting the tumor cells in non-small cell lung cancer and malignant pleural mesothelioma, Pexate 500mg Injection plays a crucial role in the treatment process for those affected by these conditions.


What conditions Pexate 500mg Injection treats?

Pexate 500mg Injection is utilized in treating non-small cell lung cancer and malignant pleural mesothelioma. Non-small cell lung cancer affects both smokers and non-smokers, and this injection can be given alone or with other medications. It is crucial to weigh the risks and benefits with your doctor before starting treatment. Malignant pleural mesothelioma, a very aggressive type of lung cancer, is treated with Pexate 500mg Injection along with other medicines. This injection works by killing cancer cells and preventing their further growth, reducing the chances of cancer spreading. Following your doctor's guidance is essential for effective treatment.


Should you consult a doctor?

Before receiving Pexate 500mg Injection, it is important to consult your doctor if you have a history of undergoing or are planning to have radiation therapy. Additionally, if you have recently received any vaccinations, it is essential to inform your doctor. These factors can impact the effectiveness and safety of the medication, and your doctor needs to be aware of your medical history to determine the best course of treatment. If you experience any unusual symptoms or side effects after receiving the injection, such as severe nausea, vomiting, or difficulty breathing, seek medical attention immediately. Your doctor will be able to provide the necessary guidance and support to ensure your well-being.


Side effects of Pexate 500mg Injection

Common side effects of Pexate 500mg Injection include nausea, vomiting, sore throat, loss of appetite, stomatitis (mouth inflammation), hair loss, low blood platelets, rash, fatigue, anemia, diarrhea, decreased white blood cell count, and neuropathy. Additionally, patients may experience rectal inflammation or bleeding, esophagus inflammation and redness, infections, fever, sore throat, stomach pain, indigestion, constipation, mouth ulcers, tiredness, dehydration, dizziness, skin rash, flaky skin, changes in sensation, eye inflammation, irregular heartbeat, liver and kidney enzyme increases, body parts swelling, and gut inflammation.

It is important to note that most side effects are temporary and may resolve as the body adjusts to the medication. However, if these side effects persist or cause concern, it is advisable to consult with a healthcare provider. In some cases, immediate medical attention is necessary if severe side effects occur after receiving Pexate 500mg Injection. These serious side effects may include fever, increased infections, chest pain, fast heart rate, mouth inflammation with pain and swelling, allergic reactions with skin rash and swelling of the face or throat, severe skin reactions with blistering and peeling, signs of low red blood cells, increased bleeding tendency, unexpected bruising, and signs of blood clot in the lungs.

If any of these serious side effects are experienced, it is crucial to contact a doctor promptly for appropriate evaluation and management.


Safety advice

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liver

When considering the use of Pexate 500mg Injection in patients with liver disease, it is likely safe based on available information. The data indicates that adjusting the dose of Pexate 500mg Injection may not be necessary for patients dealing with liver issues. However, it is essential to consult with your doctor before proceeding with this medication to ensure safety and efficacy.

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kidney

Pexate 500mg Injection requires caution in patients with kidney disease. Dose adjustment might be necessary. Avoid in cases of moderate to severe kidney issues. Consult your doctor for guidance.

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alcohol

When taking Pexate 500mg Injection, it is safe to consume alcohol as it does not lead to any negative side effects.

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driving

When using Pexate 500mg Injection, be cautious when driving as it may cause tiredness which can impact your ability to drive safely.

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pregnancy

Pexate 500mg Injection is considered unsafe during pregnancy, with a confirmed risk to the developing baby. In rare life-threatening cases, a doctor may choose to prescribe it if benefits outweigh risks. Always consult your doctor regarding its use.

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breastfeeding

During breastfeeding, Pexate 500mg Injection should be used with caution. It's recommended to pause breastfeeding until the mother's treatment is finished and the drug is fully eliminated from her body.


Age above 75(Geriatrics)

Pexate 500mg Injection should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before receiving it.

Age below 6 months(Pediatrics)

Pexate 500mg Injection is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of safety data. Therefore, consult your doctor before receiving it. 

Consumption warning before consuming Pexate 500mg Injection

Before consuming Pexate 500mg Injection, it is important to note that this medication is primarily used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma. It is administered via injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency based on your specific condition, and it is crucial to follow their instructions precisely to avoid serious side effects.

Common side effects may include nausea, vomiting, loss of appetite, and hair loss. Additionally, this medication can lower your blood cell count, making you more vulnerable to infections. Regular blood tests are necessary to monitor your blood cells, heart, liver, and blood uric acid levels.

Prior to starting treatment, inform your doctor of any existing heart, liver, or kidney ailments, as well as any other medications you are taking. It is important to avoid pregnancy while using this medication, and both males and females should use effective contraception throughout the treatment period. Be aware that certain medications may interact with or be affected by Pexate 500mg Injection, so full disclosure to your doctor about your medication regimen is crucial.


What happens if you take overdose of Pexate 500mg Injection?

Pexate 500mg Injection is typically given by a doctor or nurse in a hospital setting, reducing the risk of an overdose. It is crucial to follow medical guidance and not self-administer this medication. In the rare event of a potential overdose, symptoms may include severe nausea, vomiting, or dizziness. If you notice any unusual symptoms after receiving the injection, promptly seek advice from your healthcare provider. Your doctor or nurse can assess your condition and recommend appropriate steps to ensure your well-being. Your safety and health are of utmost importance when receiving treatment with Pexate 500mg Injection.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolites

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024