Pentasa 500mg Tablet PR

By Pentasa

Rx

10 Tablet PR in a Strip

Composition icon

Composition

Mesalazine(500mg)

Manufacturer - Ferring Pharmaceuticals icon

Manufacturer - Ferring Pharmaceuticals

K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA

Expires on or after icon

Expires on or after

May, 2027

About Pentasa 500mg Tablet PR

Pentasa 500mg Tablet PR is a type of anti-inflammatory medication specifically designed to address conditions like ulcerative colitis and Crohn's ileocolitis. Ulcerative colitis is a chronic inflammatory bowel disease causing irritation of the colon's lining, leading to ulcers, bleeding, and mucus discharge. The active ingredient in Pentasa 500mg Tablet PR is Mesalazine, which works by reducing the production of certain chemicals that trigger pain and swelling in the intestines, thereby alleviating symptoms such as stomach pain and bleeding. It is crucial to follow your doctor's instructions precisely when taking Pentasa 500mg Tablet PR and continue the treatment for the recommended duration to achieve optimal results.

When using Pentasa 500mg Tablet PR, it is important to be aware of possible side effects that may occur, including nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. While most of these side effects are temporary and do not require medical intervention, it is essential to inform your doctor if they persist or worsen. In some cases, individuals may experience severe allergic reactions, characterized by swelling of the face, tongue, throat, or lips, unusual bleeding, rash, fever, sore throat, or extreme fatigue, necessitating immediate medical attention.

Prior to initiating treatment with Pentasa 500mg Tablet PR, it is important to disclose to your healthcare provider any existing kidney or liver issues, gastrointestinal blockages, or allergies to Mesalazine or similar medications. Patients with severe kidney or liver disease are generally advised against using Pentasa 500mg Tablet PR. Pregnant or breastfeeding women should consult their healthcare provider before taking this medication, as well as individuals over the age of 65 and those under 18, due to limited data on safety and efficacy in these age groups. Additionally, if you experience significant symptoms like severe headache, stomach pain, fever, or rash, discontinue the medication immediately and seek medical guidance.

In summary, Pentasa 500mg Tablet PR is a valuable anti-inflammatory treatment option for individuals suffering from ulcerative colitis and Crohn's ileocolitis. It works by reducing inflammation in the intestines, providing relief from symptoms such as stomach pain and bleeding. Adhering to your doctor's prescribed dosage and duration of treatment is crucial for effective management of the condition. Be mindful of potential side effects, inform your healthcare provider of any pre-existing conditions or allergies, and seek medical assistance promptly in case of severe reactions.


Benefits

Pentasa 500mg Tablet PR is a beneficial medication for individuals suffering from ulcerative colitis and Crohn’s disease. In ulcerative colitis, a condition characterized by inflammation in the large intestine and rectum leading to symptoms like bleeding, frequent diarrhea, and abdominal pain, Pentasa 500mg Tablet PR can provide relief from these uncomfortable symptoms and also aid in maintaining overall well-being by preventing their recurrence. It contains Mesalazine, an anti-inflammatory drug that works by reducing the production of pain-causing substances in the body, thereby alleviating inflammation in the intestines and offering relief from symptoms such as stomach pain and bleeding. This medication may also help in preventing future episodes of ulcerative colitis, making it a valuable treatment option for individuals dealing with this condition.


In Crohn’s disease, a chronic inflammatory condition of the intestines that commonly manifests through symptoms like diarrhea and abdominal pain, Pentasa 500mg Tablet PR plays a crucial role in managing the disease. By reducing inflammation in the intestines and relieving symptoms, this medication can significantly improve the quality of life for individuals with Crohn’s disease. Moreover, Pentasa 500mg Tablet PR is effective in preventing the recurrence of symptoms, offering long-term relief and stability for patients dealing with this challenging condition.


In conclusion, Pentasa 500mg Tablet PR provides multiple benefits for individuals suffering from ulcerative colitis and Crohn’s disease. Its anti-inflammatory properties, coupled with its ability to relieve symptoms and prevent future episodes of the diseases, make it a valuable and essential treatment option for those in need of effective management and relief from the discomfort associated with these conditions.


How to use the Pentasa 500mg Tablet PR

To use Pentasa 500mg Tablet PR, it’s important to follow the advice of your doctor or carefully read the label instructions. You can take the tablet with or without food, but it is recommended to take it at a fixed time for better results. When taking the tablet form, swallow it whole with a glass of water. Do not crush, chew, or break the tablet as it may affect its effectiveness. If you are using the granule form, empty the contents directly on your tongue and then drink some water or orange juice. You can also mix the granules with yogurt and consume it immediately without chewing. For the pellet form, refer to the label directions and take it as prescribed by your doctor.


If you have been prescribed the orally disintegrating tablet, place it in your mouth and allow it to dissolve completely without swallowing or chewing. Your doctor will determine the appropriate dosage and duration of Pentasa 500mg Tablet PR based on factors such as your age, weight, and medical condition. It is important to follow the instructions provided to ensure the medication works effectively in managing your condition.


Uses of Pentasa 500mg Tablet PR

Pentasa 500mg Tablet PR is effective in treating and preventing mild to moderate cases of ulcerative colitis and Crohn’s disease. It works by reducing the symptoms associated with ulcerative colitis, such as diarrhoea, rectal bleeding, and stomach pain that can affect individuals with this condition. By taking Pentasa 500mg Tablet PR as prescribed, patients can experience relief from these uncomfortable symptoms and manage their condition more effectively.


What conditions Pentasa 500mg Tablet PR treats?

Pentasa 500mg Tablet PR is used to treat conditions such as ulcerative colitis, a chronic inflammatory bowel disease that inflames the colon and causes ulcers. Symptoms may include bloody stools, stomach pain, diarrhoea, and weight loss. It can also lead to joint pain, mouth sores, and skin problems. Factors like immune disorders, environmental triggers, and genetic predisposition can contribute to ulcerative colitis. Crohn’s disease is another inflammatory bowel condition affecting the gastrointestinal tract with symptoms like blood in stools, stomach cramps, and fatigue.


Should you consult a doctor?

It is important to seek medical advice before taking Pentasa 500mg Tablet PR if you have a history of narrowing or blockage in your stomach or gut. This medication is not recommended for children and adolescents under 18 years old due to insufficient data on its safety and effectiveness in this age group. It is crucial to consult with a doctor before giving this medicine to a child. If you experience any discomfort or adverse reactions while taking Pentasa 500mg Tablet PR, it is advisable to seek guidance from a healthcare provider promptly.


Side effects of Pentasa 500mg Tablet PR

When taking Pentasa 500mg Tablet PR, some people may experience side effects. Most of these side effects are usually mild and temporary, as your body gets used to the medication. These may include stomach pain, flatulence (gas), headache, vomiting, diarrhea, nausea, and abdominal pain. In some cases, you might also notice symptoms like bleeding and bruising, feeling sleepy, trembling, muscle pain, hair loss, ear or throat pain, a racing heartbeat, or inflammation of the pancreas.


Other potential side effects could be rectal polyps, acne, swollen face, joint or back pain, changes in blood pressure, itching, rash, kidney failure, or increased sensitivity of your skin to sunlight. If you experience more severe reactions such as serious skin conditions like Stevens-Johnson syndrome, toxic epidermal necrolysis, acute intolerance syndrome with cramping and bloody stools, unexplained bruising, signs of allergic reaction, or increased pressure in the brain, it is important to discontinue the medication immediately and seek medical attention.


It's essential to consult your doctor if any side effects persist or if you have concerns about them. Your healthcare provider can provide guidance on how to manage these side effects or adjust your treatment if needed.


Safety advice

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liver

It is important to exercise caution when using Pentasa 500mg Tablet PR in patients with liver disease. Adjusting the dosage of Pentasa 500mg Tablet PR may be necessary in such cases, hence it is advised to consult your doctor before starting the medication.

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kidney

Pentasa 500mg Tablet PR should be used cautiously in patients with kidney disease. Dose adjustment may be necessary. Avoid use in severe kidney disease. Consult your doctor for guidance.

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alcohol

Caution is necessary when consuming alcohol with Pentasa 500mg Tablet PR. It is advised to consult your doctor about alcohol intake.

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driving

Pentasa 500mg Tablet PR typically does not impair driving abilities.

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pregnancy

Pentasa 500mg Tablet PR may not be safe to use during pregnancy. Animal studies suggest potential harm to the developing baby. Please consult your doctor for a thorough evaluation of benefits and risks before using this medication.

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breastfeeding

Pentasa 500mg Tablet PR should be used with caution during breastfeeding as it may not be safe. Limited data shows a potential for the drug to pass into breastmilk and harm the baby. Monitor the baby for diarrhea while taking this medication.


Age above 75(Geriatrics)

Pentasa 500mg Tablet PR should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.


Consumption warning before consuming Pentasa 500mg Tablet PR

Before consuming Pentasa 500mg Tablet PR, ensure to inform your doctor of any allergies to Mesalazine or other medications. Caution is advised for the elderly. Pregnant or breastfeeding individuals should consult their doctor before taking Pentasa 500mg Tablet PR. It is not suitable for children under two years (tablets) or six years (granules) unless advised by a doctor. Avoid the tablet in cases of severe kidney failure. Serious skin reactions like toxic epidermal necrolysis or Stevens-Johnson syndrome may occur; seek medical attention if skin reactions appear. Discontinue use and consult a doctor if you experience stomach pain, cramps, severe headache, fever, or rash. Avoid the tablet if you have experienced blood abnormalities or kidney issues with medications like Sulphasalazine.


Disease interactions

Before taking Pentasa 500mg Tablet PR, it is essential to inform your doctor if you have a stomach ulcer, asthma, lung problems, or any medical condition that can lead to bleeding, liver issues, kidney problems, or blood disorders. This information is crucial as these existing health conditions may interact with the medication and affect its effectiveness or lead to potential complications. Ensuring that your healthcare provider is aware of your medical history will help them make informed decisions regarding the usage of Pentasa 500mg Tablet PR and adjust the dosage or recommend alternate treatment options if necessary. It is always best to disclose all relevant health information to your doctor before starting any new medication to promote safe and effective treatment outcomes.


What if you forgot to take Pentasa 500mg Tablet PR?

If you forget to take your Pentasa 500mg Tablet PR at the scheduled time, take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed one and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. This helps maintain consistency in your medication routine and ensures you are following the prescribed regimen effectively.


What happens if you take overdose of Pentasa 500mg Tablet PR?

If you or someone takes an excessive amount of Pentasa 500mg Tablet PR by accident, it is crucial to seek urgent medical attention. Notify your doctor immediately. Overdosing on this medication can lead to various symptoms such as ringing in the ears (tinnitus), dizziness, headaches, confusion, drowsiness, shortness of breath, excessive loss of fluids (resulting from sweating, diarrhea, or vomiting), light-headedness (caused by low blood sugar levels), rapid breathing, and possibly fever. Prompt action is essential in case of a suspected overdose of Pentasa 500mg Tablet PR.


Related lab tests

Related Lab Tests for monitoring patients taking Pentasa 500mg Tablet PR may include:


1. Anti Neutrophilic Cytoplasmic Antibody (ANCA) - This test helps in evaluating autoimmune diseases, including inflammatory bowel diseases.


2. Anti Saccharomyces Cerevisiae Antibodies (ASCA), IgA, and IgG - These tests may be useful in diagnosing and managing inflammatory bowel diseases, like Crohn's disease.


3. C-Reactive Protein Quantitative - This test measures the level of inflammation in the body, which can be helpful in monitoring the response to treatment with Pentasa 500mg Tablet PR.


4. Erythrocyte Sedimentation Rate (ESR) - ESR is a non-specific test that indicates inflammation in the body and can aid in monitoring the disease activity in patients with inflammatory bowel diseases.


In addition to these lab tests, healthcare providers may also recommend colonoscopy and sigmoidoscopy procedures to assess the health of the colon and detect any abnormalities. These tests are valuable for monitoring the disease progression and effectiveness of treatment in patients using Pentasa 500mg Tablet PR.


Additional Information

Habit FormingNo
Chemical ClassAminosalicylic Acids Derivative
Therapeutic Class-
Action Class5- Aminosalicylic acid (5-ASA)

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024