Penetrex Knot Tablet
By Penetrex Knot
Rx
5 Tablet in a Strip

Composition
Mifepristone(200mg) + Misoprostol(200mcg)

Manufacturer - Zydus Cadila
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after
September, 2025
About Penetrex Knot Tablet
Penetrex Knot Tablet is a combination medication used for medical abortion, which means terminating a pregnancy. It works by blocking the action of progesterone, a hormone necessary to maintain pregnancy. This blocking of progesterone helps induce contractions in the uterus, assisting in the abortion process.
It is recommended to take Penetrex Knot Tablet with food or as directed by your doctor. The treatment begins with a dose of Mifepristone, which should be swallowed whole with a glass of water. If you vomit within 30 minutes of taking the tablet, inform your healthcare provider or take another tablet. The medication may take 24-48 hours to take effect, during which you might experience spotting or bleeding. Following this, after 36-48 hours, you will need to take the Misoprostol tablet either orally or vaginally. It is advisable to rest after taking this dose as it can cause severe stomach pain or vaginal bleeding, leading to the abortion process.
Common side effects of Penetrex Knot Tablet include nausea, vomiting, diarrhea, and stomach cramps. If these side effects become bothersome or severe, it is important to inform your doctor. Some side effects, such as heavy vaginal bleeding or abdominal pain, require immediate medical attention.
Before starting this medication, inform your doctor if you have had an ectopic pregnancy, are breastfeeding, or are using an intrauterine device. Your healthcare provider should also be aware of all other medications you are taking, as some may interact with Penetrex Knot Tablet, making it less effective or altering its function. It is advised to avoid strenuous activities like heavy exercise, running, and driving during the abortion process, as it can impact bleeding. Your doctor may conduct an ultrasound or pelvic examination to ensure the completion of the abortion process.
Benefits
The Penetrex Knot Tablet is a medication used in medical abortion, particularly in the early stages of pregnancy up to week 10. This kit contains two key components, Mifepristone and Misoprostol, which work together to effectively terminate a pregnancy. Mifepristone blocks the progesterone hormone essential for pregnancy maintenance, leading to the breakdown of the uterine lining and ultimately stopping the growth of the pregnancy. It typically takes around 24-48 hours for the Penetrex Knot Tablet to start showing its effects, initially causing uterine bleeding.
However, it is important to note that the absence of uterine bleeding does not signify the completion of the abortion process. The second component, Misoprostol, plays a crucial role in this process by increasing uterine contractions and relaxing the cervix, ultimately terminating the pregnancy state. Misoprostol should be taken 24-36 hours after Mifepristone, either orally or vaginally, to ensure the effectiveness of the medication.
One key benefit of the Penetrex Knot Tablet is that it provides a non-surgical method of abortion, with a success rate of around 90%. This makes it a safe and effective option for those seeking to terminate a pregnancy in the early stages. However, it is essential to use the Penetrex Knot Tablet only as directed by a healthcare provider to ensure its safe and proper use. Overall, the Penetrex Knot Tablet offers a reliable and convenient way to induce abortion medically, providing an alternative to surgical procedures.
How to use the Penetrex Knot Tablet
To use the Penetrex Knot Tablet effectively, it is important to follow your doctor's instructions carefully. Take the medicine in the dose and duration as advised by your physician. Swallow the tablet whole with a glass of water, and do not chew, crush, or break it. It is recommended to take the Penetrex Knot Tablet with food to avoid any potential stomach discomfort. Make sure to read the label before each use, and your doctor will determine the appropriate dose based on factors such as your age, body weight, and the specific condition being treated. Always consult with your healthcare provider for proper guidance on how to use the Penetrex Knot Tablet for the best outcomes.
Uses of Penetrex Knot Tablet
The Penetrex Knot Tablet is used for medical abortion, specifically for the termination of pregnancy within 63 days after the first day of the last menstrual period. It is a method of ending a pregnancy using medications instead of surgery. This kit is designed to provide a safe and effective way for women to terminate a pregnancy in the early stages. It is important to follow the prescribed guidelines and recommendations when using the Penetrex Knot Tablet for a medical abortion.
What conditions Penetrex Knot Tablet treats?
Penetrex Knot Tablet is used for medical abortion, which is a process to end a pregnancy using medication within the first 70 days. Vaginal bleeding is expected, but if it persists, consult your doctor. Risks include incomplete abortion, prolonged heavy bleeding, fever, and digestive discomfort. Continuous medical supervision is crucial to prevent complications like unwanted pregnancy or fetal defects. Stay in close contact with your doctor and follow their guidance throughout the process.
Should you consult a doctor?
If your first day of your last period was more than 63 days ago, or if your doctor suspects you have an ectopic pregnancy, it's important to seek medical advice before using Penetrex Knot Tablet. Additionally, individuals with hereditary porphyria, chronic adrenal failure, or a history of genital cutting or circumcision should consult a doctor before taking this medication. If you suffer from a condition that affects blood clotting, are anaemic, or malnourished, it's crucial to inform your healthcare provider beforehand. Seeking professional guidance ensures your safety and proper management of any underlying health issues related to these factors.
Side effects of Penetrex Knot Tablet
When taking Penetrex Knot Tablet, you may experience certain side effects. These can include common symptoms like nausea, vomiting, diarrhea, stomach cramps, and uterine contractions. Some users might also notice heavy menstrual bleeding, dizziness, or skin rashes. In more severe cases, there could be infections following abortion, hypersensitivity reactions, or even uterine rupture. If you encounter any worrying symptoms such as severe abdominal pain, fainting, fast heartbeat, or a fever lasting more than four hours, it is crucial to stop taking the Penetrex Knot Tablet immediately and contact your doctor for further evaluation and guidance. Remember that most side effects tend to fade away as your body gets used to the medication, but it's important to seek medical advice if the symptoms persist or if you have concerns about them.
Safety advice

liver
Penetrex Knot Tablet is considered safe for use in patients with liver disease based on the limited available data. It is suggested that dose adjustment may not be required in these patients. However, it is important to consult with your doctor for proper guidance before using Penetrex Knot Tablet.

kidney
Limited information is available on using Penetrex Knot Tablet in kidney disease patients. It is recommended to consult a doctor before use.

alcohol
It is not safe to drink alcohol while using Penetrex Knot Tablet. Avoid consuming alcohol when taking this medication.

driving
When using Penetrex Knot Tablet, it may reduce alertness, impact vision, or cause drowsiness and dizziness. It is advisable to avoid driving if experiencing these symptoms.

pregnancy
During pregnancy, it is not safe to use Penetrex Knot Tablet. Studies have shown harmful effects on the developing baby in pregnant women and animals. Seek advice from your doctor before using the kit.

breastfeeding
Penetrex Knot Tablet is not safe to use while breastfeeding as it may harm the baby. Toxicity risk is a concern.
Consumption warning before consuming Penetrex Knot Tablet
Before consuming Penetrex Knot Tablet, it is important to consider certain conditions in order to avoid potential risks. Avoid taking Penetrex Knot Tablet if you are allergic to misoprostol and mifepristone, or if you have a heart with an artificial valve, heart diseases like high blood pressure, asthma, blood clotting problems, bleeding disorders, liver or kidney disease, anaemia, or malnutrition. Using Penetrex Knot Tablet in these circumstances can lead to life-threatening situations. Additionally, Penetrex Knot Tablet can cause drowsiness, so refrain from driving or operating machinery while under its influence. If you use contraceptive devices such as the intrauterine device (IUD), make sure to remove it before starting Penetrex Knot Tablet. Regular follow-up with your doctor is crucial for monitoring the abortion process. In case medical termination is unsuccessful, surgical termination may be necessary to prevent fetal defects. Avoid taking St John’s Wort or grapefruit juice while on Penetrex Knot Tablet, as they can interact and cause complications. Remember that the doctor will perform ultrasonography to confirm the completion of the abortion process.
Disease interactions
When using Penetrex Knot Tablet, it is essential to exercise caution in individuals with specific health conditions. These include a history of bleeding problems, confirmed or suspected ectopic pregnancy, heart issues, liver or kidney disease, vaginal bleeding, and porphyria, which is an inherited blood disorder that can lead to nervous system or skin complications. It is important to consider these factors before starting treatment with Penetrex Knot Tablet to ensure safe and effective use of the medication.
What if you forgot to take Penetrex Knot Tablet?
If you happen to forget to take a dose of Penetrex Knot Tablet, it is important to promptly speak with your doctor for guidance. Consulting your doctor about missed doses is crucial to ensure you are following the correct medical advice and treatment plan. Your doctor can provide specific instructions on how to proceed if you have missed a dose of Penetrex Knot Tablet. It is always best to seek professional medical advice in such situations to maintain the effectiveness of your treatment.
What happens if you take overdose of Penetrex Knot Tablet?
In case of an overdose of Penetrex Knot Tablet Tablet, it is crucial to seek medical help promptly. Taking an excessive amount of this medication can be harmful, and it is essential to consult a doctor or go to the nearest hospital if an overdose occurs. Immediate medical attention is necessary to address any potential complications that may arise from consuming too much of the Penetrex Knot Tablet Tablet.
Related lab tests
For a comprehensive evaluation when using the Penetrex Knot Tablet, it is important to consider related lab tests that can provide valuable information about your health. One important test to consider is a complete blood test, which can assess important markers such as red blood cell count, white blood cell count, and platelet count. This test can give insights into your overall health and may be helpful in monitoring any potential changes during the use of the Penetrex Knot Tablet. Additionally, a gynaecological diagnosis may be necessary to further understand any specific concerns or conditions related to reproductive health. This may include tests such as a Pap smear, pelvic exam, or specific hormonal tests to provide a comprehensive assessment of gynaecological health. By considering these related lab tests alongside the use of the Penetrex Knot Tablet, you can ensure a more thorough understanding of your health needs.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | - |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹408.3
Inclusive of all taxes
Content verified by

Dr. Gowri Kulkarni
MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)
Last update on 18-Nov-2024