Opsutan Tablet
By Opsutan
Rx
10 Tablet in a Strip

Composition
Macitentan(10mg)

Manufacturer - Cipla Ltd
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Expires on or after
October, 2025
About Opsutan Tablet
Opsutan Tablet is a prescription medication used to manage pulmonary arterial hypertension, which is characterized by high pressure in the blood vessels carrying blood from the heart to the lungs. This condition can impact the quality of life, exercise capacity, and disease progression. Opsutan Tablet can be taken alone or with other medications, with or without food. Consistent use is essential to maximize its benefits, and your doctor will determine the appropriate dosage based on your specific needs to alleviate symptoms effectively. It is crucial to adhere to the prescribed duration of treatment for optimal outcomes.
This medication contains macitentan and belongs to the class of anti-hypertensive drugs. Macitentan functions by inhibiting the action of Endothelin, a substance that narrows blood vessels and elevates blood pressure. Opsutan Tablet works by widening the narrowed pulmonary arteries, thereby enhancing blood flow and reducing blood pressure in the lungs. To ensure safe usage, always follow your doctor's instructions regarding the dosage and duration of treatment based on your individual medical condition.
Common side effects of Opsutan Tablet may include headaches, inflammation of the airways, and swelling of the legs and ankles. While most of these side effects are mild and tend to resolve over time, it is essential to inform your doctor if you experience any persistent or concerning symptoms. Serious side effects that require immediate medical attention include anemia and abnormal liver function markers such as nausea, vomiting, dark urine, fever, and fatigue. Your doctor may conduct blood tests to monitor these potential issues.
Before initiating treatment with Opsutan Tablet, inform your doctor about any existing liver conditions, pregnancy, or breastfeeding status. Additionally, disclose all other medications you are currently taking as they may impact the efficacy of Opsutan Tablet. It is recommended to refrain from driving if this medication causes dizziness. If you have allergies to macitentan or soya, liver disease, high liver enzyme levels, lung issues, or kidney problems, Opsutan Tablet may not be suitable for you. In case of worsening symptoms or concerns, do not hesitate to seek medical advice promptly.
Benefits
Opsutan Tablet offers several benefits for individuals suffering from Pulmonary arterial hypertension (PAH). PAH is a condition that can lead to symptoms such as shortness of breath, tiredness, dizziness, chest pain, and swelling in the ankles and legs. This occurs due to the thickening of the arteries' walls supplying the lungs, which makes it difficult for blood to flow through. By relaxing the blood vessels, Opsutan Tablet helps to lower the blood pressure in the arteries of the lungs.
One key benefit of Opsutan Tablet is its ability to improve the quality of life for individuals with PAH. By widening the constricted pulmonary arteries, the medication reduces the workload on the heart, making it easier for blood to flow through. As a result, individuals find it easier to carry out their daily activities, experience less fatigue, and feel less dizzy. This can significantly enhance overall well-being and help individuals better manage their condition.
In conclusion, Opsutan Tablet, with its active ingredient Macitentan, offers a targeted approach to treating PAH by addressing the underlying cause of high blood pressure in the lungs' arteries. By inhibiting the action of Endothelin and widening the narrowed blood vessels, this medication provides valuable benefits in terms of symptom relief, improved physical capabilities, and overall quality of life for individuals grappling with PAH.
How to use the Opsutan Tablet
When using Opsutan Tablet, it is essential to follow your doctor's instructions regarding the dose and duration of the medication. Swallow the tablet whole with a glass of water; do not chew, crush, or break it before consumption. You can take Opsutan Tablet with or without food, but it is recommended to take it at the same time each day. This will help you remember to take your medication regularly and maintain a consistent level of the drug in your system for optimal effectiveness. Remember not to alter the tablet in any way and always follow your doctor's guidance for the best results.
Uses of Opsutan Tablet
Opsutan Tablet is primarily used in adults to treat a condition called Pulmonary Arterial Hypertension (PAH). PAH is a form of high blood pressure that specifically affects the arteries in the lungs and the right side of the heart. By targeting this condition, Macirol helps to improve the flow of blood through these arteries, reducing the strain on the heart and improving exercise capacity. Patients suffering from PAH may experience symptoms such as shortness of breath, fatigue, chest pain, and dizziness. Opsutan Tablet plays a crucial role in managing these symptoms and enhancing the overall quality of life for individuals with PAH. It is important to follow the prescribed dosage and recommendations from healthcare professionals when using Macirol to maximize its effectiveness in treating PAH in adults.
What conditions Opsutan Tablet treats?
Opsutan Tablet is used for treating Pulmonary Arterial Hypertension, a condition where the blood vessels (pulmonary arteries) carrying blood from the heart to the lungs experience high blood pressure. This condition can strain the heart's right side as the walls of the pulmonary arteries thicken, making it hard for blood to flow through. Symptoms include shortness of breath, dizziness, palpitations, and chest pressure. It is more prevalent among individuals with existing heart or lung issues, impacting people of all age groups.
Should you consult a doctor?
If you experience side effects like headache, swelling of the legs and ankles, or inflammation of the airways while taking Opsutan Tablet, it's important to notify your doctor. Some more serious side effects that require immediate medical attention include anemia (low red blood cell count) and signs of abnormal liver function, such as nausea, vomiting, dark urine, fever, and abdominal pain. If you have any of these symptoms, contact your doctor promptly. Before starting Opsutan Tablet, inform your doctor if you have liver issues or if you are pregnant or breastfeeding. Also, discuss all other medications you are taking, as they may interact with Macirol. If you experience persistent side effects or are concerned about any symptoms, consult your doctor for further guidance. Remember to avoid driving if you feel dizzy while taking this medication.
Side effects of Opsutan Tablet
When taking Opsutan Tablet, some side effects may occur as your body gets used to the medication. These side effects include headaches, bronchitis (inflammation of the airways), nasopharyngitis (inflammation of the throat and nasal passages), anemia (low red blood cell count), urinary tract infections, and influenza. Additionally, you may experience oedema, which is swelling, particularly in the ankles and feet. Most of these side effects are temporary and should go away as your body adjusts to the medicine. However, if any of these side effects persist or if you are concerned about them, it is important to consult with your doctor for proper guidance and support.
Safety advice

liver
When taking Opsutan Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment when using Opsutan Tablet. It is advised to consult your doctor for proper guidance regarding the use of this medication in relation to liver conditions.

kidney
Use Opsutan Tablet carefully if you have kidney disease. Your doctor may need to adjust the dose. Remember to consult with your doctor.

alcohol
Consult your doctor when consuming alcohol with Opsutan Tablet.

driving
When taking Opsutan Tablet, be cautious while driving as it may cause side effects that can impact your driving ability.

pregnancy
Opsutan Tablet should be avoided during pregnancy due to potential harmful effects on the baby, as studies on pregnant women and animals have shown. Consult your doctor for proper guidance.

breastfeeding
Opsutan Tablet is not recommended during breastfeeding due to potential toxicity to the baby.
Consumption warning before consuming Opsutan Tablet
Before taking Opsutan Tablet, it is crucial to mention any allergies you have, especially to Macirol or other medications, to your doctor. Provide details about your medical history, including heart failure, liver or kidney diseases, lung conditions like pulmonary fibrosis, anaemia, oedema (fluid retention), and hypotension (low blood pressure) before beginning Opsutan Tablet. Avoid using this medication during pregnancy as it can harm the foetus; ensure you have a negative pregnancy test before starting treatment. Reliable birth control methods should be used during treatment to prevent pregnancy. If you are a breastfeeding mother, consult your doctor before taking Opsutan Tablet. Finish the prescribed course as directed by your doctor, even if you start feeling better, to prevent the disease from recurring. Due to potential side effects like dizziness and weakness that may impair concentration, refrain from driving or operating machinery while using Opsutan Tablet. Alcohol consumption should also be avoided with this medication as it can increase the risk of low blood pressure. Opsutan Tablet is not suitable for individuals under 18 years of age.
Disease interactions
When considering taking Opsutan Tablet, it is important for individuals with certain health conditions to consult their doctor beforehand. People with heart failure, liver or kidney diseases, pulmonary fibrosis, anaemia, oedema (fluid retention), low blood pressure, or severe dehydration should seek medical advice before using Macirol Tablet 10's. These conditions may interact with the medication and impact its effectiveness or lead to unwanted side effects. Therefore, to ensure safety and optimal treatment outcomes, individuals with these health issues should discuss with their healthcare provider before initiating Opsutan Tablet therapy.
What if you forgot to take Opsutan Tablet?
If you forget to take your Opsutan Tablet at the usual time, try to take it as soon as you remember. But if it's almost time for your next dose, it's better to skip the missed dose and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. Just resume taking your medication as prescribed to maintain its effectiveness.
Additional Information
Habit Forming | No |
Chemical Class | Sulfamides Derivative |
Therapeutic Class | - |
Action Class | Endothelin receptor blocker |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹2223.37
Inclusive of all taxes
Content verified by

Dr. Mansi Chaudhari
MBBS - General Medicine
Last update on 01-Oct-2024