Open-Up 300 Tablet
By Open-Up
Rx
10 Tablet in a Strip

Composition
Ursodeoxycholic Acid(300mg)

Manufacturer - Albert David Ltd
D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (WB)

Expires on or after
June, 2027
About Open-Up 300 Tablet
Open-Up 300 Tablet is a medication used to dissolve certain gallstones and prevent their formation. It is also effective in treating a liver condition known as primary biliary cirrhosis. This medicine aids in breaking down cholesterol that has solidified into stones in the gallbladder, thus facilitating their dissolution.
To ensure optimal effectiveness, Open-Up 300 Tablet should be swallowed whole after a meal, accompanied by a glass of milk or water. The dosage required will vary based on the condition being treated and individual body weight. It is essential to take this medication regularly as prescribed, even if symptoms improve, typically over several months or longer.
Like any medication, Open-Up 300 Tablet may cause some side effects, although not everyone experiences them. Common side effects include abdominal pain, diarrhea, hair loss, itching, nausea, and rash. If these side effects persist or cause concern, it's important to inform your doctor promptly.
Before starting this medication, inform your doctor if you have any history of gallbladder or bile duct inflammation, recurring cramp-like abdominal pain, unexplained weight gain, or other medical conditions. Certain medications may interact with Open-Up 300 Tablet, affecting their efficacy or side effects. Women using hormonal birth control pills are advised to discontinue them as they can increase gallstone production. Regular monitoring such as ultrasound scans or blood tests to assess liver function may also be necessary during treatment.
Open Up 300 Tablet 10's, belonging to the biliary agents group, is primarily used for gallstone dissolution and liver disease treatment. It contains ursodeoxycholic acid, a natural bile acid that reduces cholesterol production, aiding in gallstone dissolution. This medicine also protects liver cells from damage caused by toxic bile acids while enhancing liver function.
Patients are recommended to take Open-Up 300 Tablet 10's with food as prescribed by their doctor. Potential side effects may include abdominal discomfort, diarrhea, nausea, rash, dizziness, and weakness, which typically subside over time. Individuals with specific health conditions such as variceal bleeding, ascites, or liver diseases should notify their doctor before starting this medication. Avoiding alcohol consumption is advised to prevent liver damage and drowsiness when using Open-Up 300 Tablet 10's.
OPEN UP 300 TABLET is a hepatoprotective agent utilized for the treatment of primary biliary cirrhosis and the dissolution of small gallstones. Depending on the medical condition, this medication may be prescribed for children with liver disease due to cystic fibrosis. Additionally, diagnostic tests such as liver function and gall bladder scans may be required during treatment.
Prior to using OPEN UP 300 TABLET, patients should disclose any allergies to bile acids or existing conditions such as gallbladder inflammation, common bile duct blockage, or liver diseases to prevent complications. Pregnant or nursing individuals should consult with their doctor before taking this medication. The standard dosage and duration of therapy with OPEN UP 300 TABLET varies for children, adolescents, and elderly patients.
Common side effects associated with OPEN UP 300 TABLET administration include soft or loose stools, with immediate medical attention advised if symptoms deteriorate or fail to improve.
Benefits
Open-Up 300 Tablet offers various benefits in the treatment of primary biliary cirrhosis and gallbladder stones. In the case of primary biliary cirrhosis, a condition where the liver disease worsens over time, Open-Up 300 Tablet is effective in preventing or delaying liver damage. The medication can be taken alone or in combination with other medicines to manage the disease. Starting treatment early is crucial as it enhances the drug's effectiveness. It is essential to note that once treatment commences, it is usually a lifelong commitment. To optimize the medication's benefits and ensure overall well-being, individuals are advised to quit smoking, maintain a healthy weight, and moderate alcohol consumption.
For individuals with gallbladder stones, Open-Up 300 Tablet plays a vital role in reducing the production of cholesterol by the liver, aiding in the breakdown of cholesterol deposits that form stones in the gallbladder. Regular intake of the medication as prescribed by a healthcare provider is essential for successful dissolution of the stones, which may take several months. Alongside medication, lifestyle modifications and potentially other medications can assist in lowering cholesterol levels and decreasing the likelihood of developing gallstones. Consulting with a healthcare professional is recommended to explore comprehensive strategies to manage gallbladder stones effectively.
How to use the Open-Up 300 Tablet
To use Open-Up 300 Tablet, it is important to follow the dosage and duration recommended by your doctor. Swallow the tablet whole with a glass of water; do not chew, crush, or break it. It is advised to take Open-Up 300 Tablet with food to maximize its effectiveness. Make sure to consult your doctor for the proper dosage instructions tailored to your specific condition. Follow these guidelines carefully to ensure the best results from using Open-Up 300 Tablet.
Uses of Open-Up 300 Tablet
Open-Up 300 Tablet is utilized for the treatment of two main conditions. Firstly, it is used in the management of Primary Biliary Cirrhosis, a liver disease where the bile ducts in the liver are gradually destroyed. This tablet can help in alleviating symptoms and slowing down the progression of the disease. Secondly, Open-Up 300 Tablet is also employed in the treatment of Gallbladder stones. These are solid particles that form in the gallbladder and can cause pain and discomfort. By using this tablet, patients with Gallbladder stones may experience relief and improved outcomes.
What conditions Open-Up 300 Tablet treats?
Open-Up 300 Tablet is primarily used for two main conditions - to dissolve certain gallstones and to treat a liver disease known as primary biliary cirrhosis. For gallstones, it works by breaking down cholesterol that has hardened into stones in the gallbladder, helping to dissolve them over time. When used to treat primary biliary cirrhosis, it can prevent or delay liver damage, especially if started early. This condition is a liver disease that worsens gradually and can lead to liver failure if left untreated. Taking Open-Up 300 Tablet regularly as prescribed is important for both conditions.
Should you consult a doctor?
Seek medical attention if you experience persistent or concerning side effects like abdominal pain, diarrhea, hair loss, itching, nausea, or rash while taking Open-Up 300 Tablet. Inform your doctor if you have inflammation of the gallbladder or bile ducts, frequent cramp-like upper abdominal pain, coughing up blood, or rapid weight gain before starting this medication. Be cautious about interactions with other drugs and discontinue hormonal birth control pills as advised. Regular monitoring through ultrasound scans and blood tests may be necessary during treatment to assess liver function. Follow your healthcare provider's instructions on dosage and duration. If symptoms do not improve or if you have any worries about your condition, consult your doctor promptly.
Side effects of Open-Up 300 Tablet
When taking Open-Up 300 Tablet, some side effects may occur. Most side effects are minor and may go away as your body gets used to the medicine. Common side effects include abdominal pain, diarrhea, hair loss, itching, nausea, and rash. If any of these side effects persist or cause concern, it is important to consult your doctor.
Safety advice

liver
Limited information is currently available regarding the use of Open-Up 300 Tablet in individuals with liver disease. It is strongly recommended to consult with your healthcare provider before using this medication, especially if you have any existing liver issues. Your doctor will be able to provide you with personalized guidance and determine the most appropriate course of action to ensure your safety and well-being while taking Open-Up 300 Tablet.

kidney
Limited information is available regarding the use of Open-Up 300 Tablet in patients with kidney disease. It is advisable to consult your doctor before using this medication.

alcohol
Open-Up 300 Tablet can increase drowsiness with alcohol.

driving
When taking Open-Up 300 Tablet, it is typically safe to drive as it does not usually affect your driving ability.

pregnancy
Open-Up 300 Tablet is generally safe to use during pregnancy based on animal studies with minimal adverse effects on the baby, but human studies are limited. It is advisable to consult a healthcare provider before use.

breastfeeding
Open-Up 300 Tablet is considered safe for breastfeeding. Limited data shows no significant risk to the baby.
Consumption warning before consuming Open-Up 300 Tablet
Before consuming Open-Up 300 Tablet, it is essential to be cautious of certain aspects. This medication is primarily used to dissolve gallstones and prevent their formation, as well as to treat primary biliary cirrhosis. To ensure its effectiveness, swallow the tablet whole after a meal with a glass of milk or water. The dosage will be determined based on your condition and body weight, so it's crucial to take it regularly for maximum benefits, even if symptoms improve. Common side effects may include abdominal pain, diarrhea, hair loss, itching, nausea, and rash. If you experience persistent concerns or side effects, notify your doctor. Prior to taking Open-Up 300 Tablet, inform your healthcare provider if you have specific conditions such as gallbladder or bile duct inflammation, cramp-like upper abdominal pain, coughing up blood, or rapid weight gain. Additionally, discuss all other medications you are taking, as interactions can occur. Women using hormonal birth control pills should discontinue them, as they may impact gallstone production. Throughout treatment, regular ultrasound scans and liver function tests may be necessary for monitoring.
What if you forgot to take Open-Up 300 Tablet?
If you forget to take a dose of Open-Up 300 Tablet, simply skip that missed dose and resume your regular dosing schedule. It's important not to take a double dose to make up for the missed one. Just continue with your next scheduled dose as usual. This will help maintain the effectiveness of the medication and reduce the risk of potential side effects. Remember to always follow your prescribed dosing instructions to ensure the best possible outcomes.
Related lab tests
For people taking Open-Up 300 Tablet, it is important to monitor their liver health regularly. One common way to do this is through a Liver Function Test. This test helps assess how well the liver is functioning by measuring various enzymes, proteins, and substances in the blood that are produced or excreted by the liver. Some of the key parameters tested in a Liver Function Test include ALT (Alanine aminotransferase), AST (Aspartate aminotransferase), ALP (Alkaline phosphatase), bilirubin, and albumin levels. These tests can provide valuable insights into liver health, detect any abnormalities early on, and help healthcare providers adjust treatment plans if needed.
In addition to the Liver Function Test, there are other related lab tests that may be recommended for individuals using Open-Up 300 Tablet to further monitor their liver function and overall health. Some of these tests include:
1. Complete Blood Count (CBC) - This test helps evaluate overall health and can detect infections, anemia, and other blood disorders.
2. Lipid Profile - This test measures cholesterol and triglyceride levels in the blood, which are important indicators of cardiovascular health.
3. Kidney Function Tests - Tests such as creatinine and blood urea nitrogen (BUN) can assess kidney function, as the kidneys play a role in filtering waste products from the blood.
4. Electrolyte Panel - This test measures levels of electrolytes such as sodium, potassium, and calcium, which are essential for various bodily functions.
5. Thyroid Function Tests - These tests assess thyroid hormone levels, which can impact metabolism and overall health.
By regularly monitoring these related lab tests in addition to the Liver Function Test, individuals taking Open-Up 300 Tablet can ensure their liver and overall health are being closely monitored, and any potential issues can be addressed promptly.
Additional Information
Habit Forming | No |
Chemical Class | Bile Acids and Salts |
Therapeutic Class | GASTRO INTESTINAL |
Action Class | Hepatoprotectives |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹371.61
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Content verified by

Dr. Upasana Bhatia
MBBS - General Medicine
Last update on 01-Oct-2024