Olvorin 300mg Injection

By Olvorin

Rx

1 Injection in a Vial

Composition icon

Composition

Calcium Leucovorin(300mg)

Manufacturer - Neova Biogene Private Limited icon

Manufacturer - Neova Biogene Private Limited

322, Monte Plaza Marathon, Mulund (W), Mumbai

Expires on or after icon

Expires on or after

October, 2025

About Olvorin 300mg Injection

Introduction:

Olvorin 300mg Injection is a medication that plays a crucial role in safeguarding against the detrimental effects of methotrexate, an anticancer drug, and also serves as a remedy for methotrexate overdose. This injectable solution is administered slowly into the veins by a healthcare professional, with close supervision to ensure proper dosage and frequency tailored to individual patient needs. Adherence to the doctor's instructions is paramount as incorrect usage or overconsumption of Olvorin can lead to severe adverse reactions.

Common side effects of Olvorin 300mg Injection include localized reactions at the injection site such as pain, swelling, and redness. It is essential to promptly inform your doctor if these side effects become bothersome or alarming, as there are measures available to alleviate or prevent them. Regular monitoring through blood tests is necessary to assess blood cell count and the concentration of methotrexate in the bloodstream.

Before initiating Olvorin therapy, it is crucial to disclose to your healthcare provider any history of seizures, liver or kidney issues, or current use of medications for infections. Given the potential for interactions with various other drugs, especially phenytoin for seizure management, it is imperative to provide a comprehensive list of all medications in use. Pregnant or breastfeeding individuals should inform their doctor beforehand to ensure the safety and appropriateness of Olvorin 300mg Injection for their specific situation.


Benefits

Olvorin 300mg Injection offers important benefits in preventing the harmful effects of the anti-cancer medicine methotrexate. By safeguarding the body cells from these harmful effects, Olvorin 300mg Injection plays a crucial role in ensuring the effectiveness of methotrexate in fighting cancer. It is administered as a form of vitamin B, typically given 24 hours after methotrexate treatment to maximize its protective effects. In addition to enhancing the anti-cancer properties of methotrexate, Olvorin 300mg Injection also helps to prevent side effects like anemia, making it an essential component in cancer therapy.


How to use the Olvorin 300mg Injection

When using Olvorin 300mg Injection, it is important to remember that only your doctor or nurse should administer this medicine. It should not be self-administered. This means you should not try to inject the medication yourself. Trust the healthcare professional to handle the injection for you. By following this guideline, you can ensure the proper and safe use of Olvorin 300mg Injection as prescribed by your healthcare provider.


Uses of Olvorin 300mg Injection

Olvorin 300mg Injection is used to prevent the harmful effects of methotrexate. It is commonly prescribed to patients undergoing treatment with methotrexate in order to reduce or eliminate the potential side effects associated with this medication. This injection helps in protecting the body from the toxic effects of methotrexate and supports the effectiveness of the treatment. By administering Olvorin 300mg Injection alongside methotrexate therapy, healthcare providers aim to ensure a smoother and more successful treatment course for patients.


What conditions Olvorin 300mg Injection treats?

Olvorin 300mg Injection is essential in protecting the body cells from the harmful effects of methotrexate, an anticancer medicine. It works by ensuring that methotrexate achieves its anticancer effects while also preventing side effects like anemia. This injection is administered slowly into the veins by a healthcare professional, with dosage and frequency determined by your doctor based on your condition. Common side effects include injection site reactions which can be managed, and regular blood tests are needed to monitor your blood cells and methotrexate levels. Prior medical conditions and medications should be discussed with your doctor before using Olvorin 300mg Injection.


Should you consult a doctor?

If you experience injection site reactions such as pain, swelling, or redness that bother you or seem severe, it is important to inform your doctor. Additionally, seek medical attention if these reactions persist or if you have concerns about them. It is crucial to have regular blood tests to monitor your blood cells and serum methotrexate levels. Consult your doctor before taking Olvorin 300mg Injection if you have a history of seizures, liver or kidney issues, or if you are using medications for infections. Inform your healthcare provider about all the medicines you are taking, especially phenytoin for seizures. Prior to taking this medication, notify your doctor if you are pregnant or breastfeeding to ensure its safety for you and your baby. It is essential to follow your doctor's instructions regarding dosage and administration to prevent serious side effects that may arise from incorrect usage.


Side effects of Olvorin 300mg Injection

When using Olvorin 300mg Injection, some individuals may experience side effects, with the most common being related to injection site reactions. These reactions can include pain, swelling, and redness at the site where the injection was administered. It is important to note that most side effects are mild and temporary, typically resolving as the body gets used to the medication. However, if these side effects persist or cause concern, it is advisable to consult with a healthcare provider for further evaluation and guidance.


Safety advice

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liver

Limited information is accessible regarding the use of Olvorin 300mg Injection in individuals with liver conditions. It is advisable to seek advice from your healthcare provider before using this medication if you have liver issues.

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kidney

Limited information is available on Olvorin 300mg Injection use in kidney disease patients. Kindly consult your doctor.

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alcohol

Consult your doctor when consuming alcohol with Olvorin 300mg Injection.

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driving

When using Olvorin 300mg Injection, it is generally considered safe to drive as it does not typically impact your driving abilities.

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pregnancy

Olvorin 300mg Injection may not be safe to use during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will assess the benefits versus risks before prescribing. Please consult your doctor regarding its use during pregnancy.

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breastfeeding

It is better to consult your doctor before using Olvorin 300mg Injection.


Consumption warning before consuming Olvorin 300mg Injection

Before consuming Olvorin 300mg Injection, it is crucial to be aware of certain important information. This injection is primarily used to counteract the adverse effects of methotrexate, an anticancer medication, and to manage methotrexate overdose. It is administered as a slow intravenous injection under the supervision of a healthcare provider. The dosage and frequency of administration will be determined by your doctor based on your specific condition, and it is imperative to strictly follow their instructions to avoid potential severe side effects.

Common side effects of Olvorin 300mg Injection include injection site reactions such as pain, swelling, and redness. If you experience any concerning or persistent side effects, it is essential to inform your doctor promptly for appropriate management. Regular blood tests are necessary to monitor blood cell counts and serum methotrexate levels.

Prior to using this medication, inform your doctor about any history of seizures, liver or kidney issues, and current use of any other medications, especially those for infections or seizures like phenytoin. It is important to disclose all medications you are taking to prevent potential interactions. Additionally, if you are pregnant or breastfeeding, consult your doctor to ensure the safety of using Olvorin 300mg Injection.


What if you forgot to take Olvorin 300mg Injection?

If you forget to take your Olvorin 300mg Injection, try to take it as soon as you remember. But if it's almost time for your next scheduled dose, it's better to skip the missed one. Avoid taking a double dose to make up for the one you missed. This helps maintain your regular dosing schedule and reduces the risk of potential side effects.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic Class-
Action ClassCytoprotective agents- methotrexate

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025