Olvorin 100mg Injection
By Olvorin
Rx
1 Injection in a Vial

Composition
Calcium Leucovorin(100mg)

Manufacturer - Neova Biogene Private Limited
322, Monte Plaza Marathon, Mulund (W), Mumbai

Expires on or after
July, 2026
About Olvorin 100mg Injection
Olvorin 100mg Injection is a medication used to protect against the harmful effects of methotrexate, which is a type of anticancer medicine. It is also utilized to manage cases of methotrexate overdose. The injection is administered slowly into the veins, under the close supervision of a medical professional. Your doctor will determine the appropriate dosage and frequency of administration based on your specific condition, which may vary over time. It is crucial to follow your doctor's instructions precisely when taking this medication to avoid severe side effects resulting from improper dosing.
Common side effects of Olvorin 100mg Injection include reactions at the injection site such as pain, swelling, and redness. If these reactions are bothersome or seem severe, it is essential to inform your doctor. There may be strategies to alleviate or prevent these side effects. Regular blood tests are necessary to monitor your blood cells and the concentration of methotrexate in your blood.
Prior to taking Olvorin 100mg Injection, it is important to inform your doctor if you have a history of seizures, liver or kidney issues, or if you are using any medications for treating infections. This medication can interact with numerous other drugs, especially phenytoin used for seizures, so it is important to disclose all medications you are currently taking to your healthcare provider. If you are pregnant or breastfeeding, it is crucial to discuss this with your doctor before initiating treatment with Olvorin 100mg Injection to ensure its safety for you and your baby.
Benefits
Olvorin 100mg Injection offers important benefits in protecting the body from the harmful effects of methotrexate, a powerful anti-cancer medication. This injection contains a specific form of vitamin B that shields the body's cells from the damaging impact of methotrexate. It is administered 24 hours after methotrexate to ensure its anti-cancer effects take place. By using Olvorin 100mg Injection in conjunction with methotrexate, patients can minimize the occurrence of side effects like anemia and other potential complications. This makes Olvorin 100mg Injection a valuable addition to cancer treatment regimens by promoting the efficacy of methotrexate while safeguarding the body against its harmful effects.
How to use the Olvorin 100mg Injection
When using Olvorin 100mg Injection, it is important to remember that only a doctor or nurse should administer this medicine to you. Avoid trying to self-administer this injection as it requires proper medical supervision. Your healthcare provider will determine the correct dosage and frequency of administration based on your specific condition. Be sure to follow their instructions carefully. Before the injection, the healthcare provider will prepare the injection site and administer the medication safely. It is essential to inform your doctor about any other medications or medical conditions you have before starting Olvorin 100mg Injection to ensure it is safe for you. If you have any questions or concerns about how to use this medication, do not hesitate to ask your healthcare provider for guidance.
Uses of Olvorin 100mg Injection
Olvorin 100mg Injection is commonly used to prevent the harmful effects of methotrexate. Methotrexate is a medication used to treat certain types of cancer, rheumatoid arthritis, and other autoimmune conditions. However, it can also cause various side effects, such as liver damage and low blood cell counts. By using Olvorin 100mg Injection along with methotrexate treatment, the potential harmful effects of methotrexate can be reduced. This helps in improving the overall safety and effectiveness of methotrexate therapy, making it a valuable addition to the treatment regimen for patients undergoing methotrexate treatment.
What conditions Olvorin 100mg Injection treats?
Olvorin 100mg Injection is used to prevent the harmful effects of methotrexate, an anti-cancer medicine. It helps protect body cells from methotrexate's harmful impact, serving as a form of vitamin B. Administered 24 hours after methotrexate, it ensures the medication's anti-cancer effects are achieved and prevents side effects like anemia. Regular blood tests are needed to monitor blood cells and methotrexate concentration. Inform your doctor about any preexisting conditions or medications, especially phenytoin for seizures. Side effects like injection site reactions are common but usually temporary.
Should you consult a doctor?
If you experience persistent injection site reactions such as pain, swelling, or redness after receiving Olvorin 100mg Injection, it is important to seek medical attention. Additionally, if these side effects become severe or bothersome, it is advisable to inform your doctor. Regular blood tests are necessary to monitor your blood cells and methotrexate concentration levels, so if you notice any unusual symptoms or have concerns about your blood test results, consult your healthcare provider. Inform your doctor if you have a history of seizures, liver or kidney issues, or are taking other medications, especially phenytoin. Furthermore, for pregnant or breastfeeding individuals, it is crucial to discuss the potential risks and benefits of Olvorin 100mg Injection with your doctor before starting treatment. Remember to follow your doctor's dosage instructions precisely to avoid serious side effects from improper use.
Side effects of Olvorin 100mg Injection
When using Olvorin 100mg Injection, some common side effects may occur, specifically at the injection site. These can include pain, swelling, and redness. In most cases, these side effects are temporary and will go away as your body gets used to the medication. However, if these reactions persist or if you are concerned about them, it is important to consult your doctor for further guidance.
Safety advice

liver
"Olvorin 100mg Injection should be used with caution in patients with liver disease. Limited information is available regarding its use in such patients. It is advised to consult with your doctor before using this medication if you have any liver issues."

kidney
Limited information exists on using Olvorin 100mg Injection in individuals with kidney disease. It is crucial to seek advice from your doctor.

alcohol
Consult your doctor when consuming alcohol with Olvorin 100mg Injection.

driving
Olvorin 100mg Injection typically does not impact driving ability.

pregnancy
Olvorin 100mg Injection might not be safe during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will assess the risks and benefits before prescribing. Kindly consult your doctor.

breastfeeding
It is better to consult your doctor before using Olvorin 100mg Injection during breastfeeding.
Consumption warning before consuming Olvorin 100mg Injection
Before consuming Olvorin 100mg Injection, it is important to be aware of certain precautions. This injection is mainly used to counteract the harmful effects of methotrexate, an anticancer medication, as well as to treat methotrexate overdose. Administration of Olvorin 100mg Injection should only be done through a slow injection into the veins while being monitored by a healthcare professional. The dosage and frequency will be determined by your doctor based on your condition, so it is crucial to strictly adhere to their instructions. Incorrect usage or overdosage can lead to severe side effects.
Common side effects of Olvorin 100mg Injection include injection site reactions such as pain, swelling, and redness. If these reactions are bothersome or become severe, consult your doctor for possible remedies. Regular blood tests are necessary to monitor blood cell count and methotrexate levels. Inform your doctor about any history of seizures, liver or kidney issues, or current use of medications, especially phenytoin. It is essential to disclose all medications you are taking to avoid potential interactions. Before using this injection, notify your doctor if you are pregnant or breastfeeding to ensure safety.
What if you forgot to take Olvorin 100mg Injection?
If you forget to take your Olvorin 100mg Injection at the scheduled time, try to take it as soon as you remember. In case your next dose is approaching, it's best to skip the missed dose and stick to your normal dosing routine. Avoid taking a double dose to make up for the missed one. It's important to follow the proper dosing schedule to ensure the medication works effectively.
Additional Information
| Habit Forming | No |
| Chemical Class | Glutamic Acid Derivatives |
| Therapeutic Class | - |
| Action Class | Cytoprotective agents- methotrexate |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹980
Inclusive of all taxes
Content verified by

Dr. Upasana Bhatia
MBBS - General Medicine
Last update on 11-Feb-2025
