Olkem Trio 12.5 Tablet
By Olkem Trio
Rx
10 Tablet in a Strip

Composition
Olmesartan Medoxomil(20mg) + Cilnidipine(10mg) + Chlorthalidone(12.5mg)

Manufacturer - Alkem Laboratories Ltd
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Expires on or after
May, 2026
About Olkem Trio 12.5 Tablet
Olkem Trio 12.5 Tablet is a medication designed to effectively treat hypertension (high blood pressure) by combining three main active ingredients: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone. Hypertension is a chronic condition where the force of blood against artery walls is elevated, potentially leading to heart diseases and other complications.
Olmesartan medoxomil works by blocking the hormone angiotensin, which helps relax blood vessels, enabling smoother blood flow and improved heart pumping efficiency. Cilnidipine acts by blocking calcium channels within the heart's blood vessels, thereby reducing the heart's workload and enhancing overall blood-pumping efficiency. Lastly, Chlorthalidone, a diuretic, eliminates excess water and certain electrolytes from the body, effectively lowering blood pressure and minimizing the risk of heart attack or stroke.
It is crucial to take Olkem Trio 12.5 Tablet with food as prescribed by the doctor and should be swallowed whole with a glass of water without crushing or breaking it. The dosage and duration will be determined by your medical condition. Potential side effects may include headache, nausea, peripheral edema (swelling of legs/hands), or dizziness, which typically subside over time without medical intervention. However, persistent side effects should be reported to the doctor promptly.
Discontinuing the use of Olkem Trio 12.5 Tablet without medical advice can elevate blood pressure levels, potentially increasing the risks of stroke and heart diseases. Caution must be exercised when using this medication in patients with specific conditions such as chest pain (angina), kidney disease, heart failure, low blood pressure (hypotension), or cardiogenic shock (sudden blood flow stoppage to the heart). Patients who are pregnant or breastfeeding should inform their doctor for appropriate dosage adjustments.
It is essential to consult your doctor before using Olkem Trio 12.5 Tablet if you have any liver or kidney problems, are pregnant, or are currently breastfeeding. Regular monitoring of blood pressure, kidney function, electrolyte levels, and blood sugar levels is advised to ensure the effectiveness of the medication. Additionally, informing your doctor about other medications you are currently taking, especially those for high blood pressure or heart conditions, is crucial.
Benefits
Olkem Trio 12.5 Tablet is a powerful medication that offers numerous benefits for individuals dealing with hypertension, commonly known as high blood pressure. This tablet contains a combination of three key medicines: Olmesartan medoxomil, Clindipine, and Chlorthalidone, all working together to effectively lower elevated blood pressure levels.
Olmesartan medoxomil in the tablet functions by blocking the hormone angiotensin, which results in the relaxation of blood vessels. This relaxation allows blood to flow more smoothly throughout the body, enabling the heart to pump blood more efficiently. In combination, Cilnidipine works by blocking calcium channels in the blood vessels of the heart. By reducing the heart's workload, it enhances the heart's ability to efficiently pump blood, consequently lowering high blood pressure and decreasing the risk of heart attacks or strokes.
Chlorthalidone, another component of the tablet, acts as a diuretic by eliminating excess water and certain electrolytes from the body. This process helps in effectively reducing blood pressure levels, contributing to overall cardiovascular health. The combined effects of these three medicines working together aim to keep your blood pressure under control, ultimately minimizing the likelihood of experiencing a stroke, heart attack, or kidney issues in the future.
It is essential to take Olkem Trio 12.5 Tablet regularly as prescribed by your healthcare provider to maximize its effectiveness, even if you do not notice immediate benefits. Consistent usage of this medication plays a crucial role in maintaining your well-being in the long term. By incorporating Olkem Trio 12.5 Tablet into your daily routine as directed, you are actively investing in the management and improvement of your high blood pressure condition, ensuring a healthier future for yourself.
How to use the Olkem Trio 12.5 Tablet
To use Olkem Trio 12.5 Tablet effectively, follow these simple steps. Take the medicine exactly as your doctor has advised - this is important. Swallow the tablet whole with a glass of water, preferably with your meal. Do not chew, crush, or break the tablet as it is meant to be taken as a whole. Taking Olkem Trio 12.5 Tablet with food helps in its slow absorption and reduces the risk of sudden drops in blood pressure. Remember, only your doctor can determine the right dose and duration based on factors like your age, weight, and medical condition. So, always follow your physician's instructions for the best results.
Uses of Olkem Trio 12.5 Tablet
Olkem Trio 12.5 Tablet is used to help manage essential hypertension, which is another term for high blood pressure. This medication is specifically designed to treat this condition and can be beneficial for individuals who have been diagnosed with hypertension. By taking Olkem Trio 12.5 Tablet as prescribed by a healthcare provider, patients can work towards controlling their high blood pressure and reducing the associated health risks.
What conditions Olkem Trio 12.5 Tablet treats?
High blood pressure, also known as hypertension, is a chronic condition where the force of blood flow is too high. This can lead to health issues like hardened arteries, chest pain, heart attack, stroke, and kidney failure. Monitoring blood pressure with a sphygmomanometer is essential in diagnosing hypertension. Systolic pressure measures when the heart pumps, while diastolic pressure is when the heart is at rest. An ideal blood pressure range is between 90/60 mm Hg and 120/80 mm Hg.
Should you consult a doctor?
It is important to seek a doctor's advice before taking Olkem Trio 12.5 Tablet if you have certain health conditions. Avoid using this medication if you have low potassium or sodium levels, high calcium or urea levels, gout, or Addison's disease. Additionally, inform your doctor if you have diabetes or adrenal gland issues before starting treatment with Olkem Trio 12.5 Tablet. Consulting with a healthcare professional is crucial to ensure the safe and effective use of this medication based on your individual health conditions.
Side effects of Olkem Trio 12.5 Tablet
Some common side effects of Olkem Trio 12.5 Tablet include ankle swelling, headache, dizziness, tiredness, palpitations, sleepiness, increased blood uric acid, glucose intolerance, taste change, flushing (sense of warmth in the face, ears, neck, and trunk), upset stomach, and altered blood lipid levels. You may also experience peripheral edema (swelling of legs/hands), rash, breathing problems, vomiting, weakness, muscular pain, skin rash, allergic skin rash, itching, angina (chest pain or discomfort), signs of low platelet count (easy bleeding or bruising), nausea, indigestion, diarrhea, stomach pain, gastroenteritis (intestinal infection with symptoms like diarrhea, cramps, nausea, vomiting, and fever), sore throat, runny or stuffy nose, cough, shortness of breath, fever, chills, chest pain, back pain, bone pain, joint pain, bladder pain, foul-smelling or cloudy urine, frequent urination (signs of urinary tract infection), weight gain, intense joint pain, inflammation, redness (signs of high uric acid in blood), yellowing of the skin and eyes (jaundice - sign of liver damage), lack of energy, muscle cramps, loss of appetite, decreased urinary output, fatigue (signs of kidney failure), muscle spasms, abnormal heart rhythm (signs of high potassium levels). In case of experiencing any severe side effects like low blood pressure leading to severe light-headedness or fainting, you should stop taking Olkem Trio 12.5 Tablet immediately and contact your doctor. Remember that most side effects may subside as your body adjusts to the medication, but consult your doctor if they persist or you are concerned about them.
Safety advice

liver
Olkem Trio 12.5 Tablet should be used with caution if you have liver disease. It may be necessary to adjust the dosage of the tablet in such cases, so remember to seek guidance from your doctor before using it. It is important to note that Olkem Trio 12.5 Tablet is not recommended for individuals with severe liver disease.

kidney
Caution should be taken when using Olkem Trio 12.5 Tablet in patients with severe kidney disease. Dose adjustment may be required, and it is advised to consult a doctor. Avoid using this tablet in patients with severe kidney issues.

alcohol
Olkem Trio 12.5 Tablet can make you very drowsy when taken with alcohol.

driving
When taking Olkem Trio 12.5 Tablet, be cautious while driving as it may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if experiencing these effects.

pregnancy
Olkem Trio 12.5 Tablet is not safe to use during pregnancy due to the risk to the developing baby. However, in life-threatening situations, a doctor may prescribe it if the benefits outweigh the risks. It is important to seek medical advice.

breastfeeding
It is better to consult your doctor before using Olkem Trio 12.5 Tablet.
Age above 75(Geriatrics)
Olkem Trio 12.5 Tablet should be used with caution in elderly patients of 65 years and above. Before taking Olkem Trio 12.5 Tablet, consult your doctor.
Age below 6 months(Pediatrics)
Safety and efficacy in pediatric patients is not established. Consult your doctor before taking Olkem Trio 12.5 Tablet.
Consumption warning before consuming Olkem Trio 12.5 Tablet
Before consuming Olkem Trio 12.5 Tablet , it is important to note that this medication should not be taken by individuals who are allergic to it, have low blood pressure, have a history of heart attack, kidney disease, liver disease, or are pregnant, planning to become pregnant, or breastfeeding. Additionally, Olkem Trio 12.5 Tablet is not suitable for individuals with conditions such as low blood pressure (hypotension), cardiogenic shock, or aortic stenosis. It is advised to inform your doctor if you are breastfeeding while taking this medication, as it can pass into breast milk with unknown effects on the baby. Avoid consuming grapefruit juice and St. John's wort plant alongside Olkem Trio 12.5 Tablet . This medication contains hydrochlorothiazide, which may lead to low potassium, low sodium, and low magnesium levels, requiring regular monitoring of electrolytes during treatment. Do not use Olkem Trio 12.5 Tablet if you have low urine output, are allergic to other sulfonamide antibiotics, are taking aliskiren, or have diabetes. Lastly, refrain from consuming alcohol while on this medication, as it can result in low blood pressure.
What if you forgot to take Olkem Trio 12.5 Tablet?
If you forget to take a dose of Olkem Trio 12.5 Tablet, take it as soon as you remember. But if it's near the time for your next dose, just skip the missed one and continue with your usual dosing schedule. Avoid taking a double dose to make up for the missed one.
What happens if you take overdose of Olkem Trio 12.5 Tablet?
In case of accidentally taking too much Olkem Trio 12.5 Tablet, it is important to seek medical help promptly. Overdosage of this medication can lead to various symptoms such as low blood pressure, dizziness, nausea, sleepiness, and disturbances in electrolyte levels that can affect the heart rhythm and cause muscle stiffness. If you experience any of these symptoms, it is crucial to consult a doctor or go to the nearest hospital for immediate assistance.
Related lab tests
For individuals taking Olkem Trio 12.5 Tablet, it is important to monitor kidney function regularly. This can be done through a kidney function test, which helps evaluate how well the kidneys are working. The test includes assessing the levels of substances like creatinine and urea in the blood to determine kidney health.
Related Lab Tests:
1. Serum Creatinine Test
2. Blood Urea Nitrogen (BUN) Test
3. Estimated Glomerular Filtration Rate (eGFR) Test
4. Urinalysis
5. Electrolyte Panel Test
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | CARDIAC |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹193.5
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024