Nublexa Tablet

By Nublexa

Rx

28 Tablet in a Strip

Composition icon

Composition

Regorafenib(40mg)

Manufacturer - Bayer Zydus Pharma Pvt Ltd icon

Manufacturer - Bayer Zydus Pharma Pvt Ltd

Bayer House, Central Avenue, Hiranandani Estate, Thane (west) Thane 400607 India

Expires on or after icon

Expires on or after

May, 2026

About Nublexa Tablet

Nublexa Tablet is a type of medication known as Tyrosine kinase inhibitors, which are commonly used in the treatment of colon and rectal cancer. It is essential to take Nublexa Tablet with food, preferably at the same time each day in order to maximize its benefits. Your doctor will determine the appropriate dosage and frequency of intake based on your specific condition, which may vary over time. It is crucial to follow your doctor’s instructions precisely to avoid serious side effects that can result from incorrect usage or overdose.

When taking Nublexa Tablet, it is important to be aware of potential side effects. Some common side effects include infections, low blood platelet count, anemia, decreased appetite, hemorrhage, and high blood pressure. Additional side effects may include changes in voice, diarrhea, mouth inflammation, vomiting, nausea, presence of bilirubin in urine, elevated liver enzymes, skin rash, weakness, pain, fever, inflammation of mucous membranes, and weight loss. If any of these side effects become bothersome, it is advisable to inform your doctor promptly. Regular blood tests are also recommended to monitor blood cell counts and liver function.

Nublexa Tablet may interact with other medications, so it is essential to inform your healthcare provider about all the medications you are currently using. This medication is not recommended for use during pregnancy or while breastfeeding. Effective contraception is strongly advised for both males and females during treatment to prevent unintended pregnancy.

NUBLEXA 40MG TABLET 28'S is an anti-cancer medication specifically used in the treatment of colorectal carcinoma. This type of cancer involves the uncontrolled growth of malignant cells in the colon or rectum. NUBLEXA 40MG TABLET 28'S contains Regorafenib as the active ingredient, which belongs to the class of kinase inhibitors. By inhibiting the action of the enzyme tyrosine kinase, this medication helps to halt the abnormal growth of cancer cells.

It is normal to experience certain side effects while taking NUBLEXA 40MG TABLET 28'S, such as diarrhea, rash, fatigue, decreased appetite, nausea, weight loss, abdominal pain, loss of appetite, hoarseness, and dizziness. These side effects typically resolve on their own over time and do not usually require medical intervention. If you are allergic to any components of NUBLEXA 40MG TABLET 28'S or have a history of certain medical conditions such as liver or kidney disease, gastrointestinal disorders, hypertension, heart issues, blood disorders, or skin disorders, it is important to inform your doctor before starting this medication. Pregnant and breastfeeding women are advised against using this medication due to potential risks to the fetus or infant.


Benefits

The Nublexa Tablet, containing Regorafenib, offers several benefits in the treatment of colorectal cancer (CRC). This medication is specifically used for patients who have previously undergone fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, antiVEGF therapy, and possibly anti-EGFR therapy if they have KRAS wild type. Nublexa Tablet works by targeting and stopping the action of a tyrosine kinase enzyme responsible for the multiplication of cancer cells. By inhibiting this enzyme, it effectively halts the abnormal growth of cancer cells, reducing the risk of further spread to other parts of the body.

One of the key benefits of Nublexa Tablet is its ability to treat existing cancerous growths and lower the risk of developing additional cancerous growths, such as polyps, in the colon and rectum. Moreover, this medication is known for its efficacy in killing or inhibiting the growth of cancer cells, thereby preventing their multiplication and spread. By effectively targeting these cancer cells, Nublexa Tablet plays a crucial role in impeding the body's production, spread, and growth of cancer cells associated with colorectal cancer.

However, it is essential to note that Nublexa Tablet is a potent and potentially toxic medicine. Therefore, it is imperative to consult with a healthcare professional to discuss the associated risks and benefits before initiating treatment. Additionally, individuals undergoing treatment with Nublexa Tablet should avoid alcohol and smoking to optimize the medication's efficacy. Staying hydrated by consuming an adequate amount of water is also crucial during the treatment with this medication.

In conclusion, Nublexa Tablet, with its active component Regorafenib, offers significant benefits in the management of colorectal cancer by targeting cancerous cells and hindering their growth and spread. By understanding its mechanism of action and consulting with healthcare providers, patients can maximize the therapeutic benefits of Nublexa Tablet in their cancer treatment regimen.


How to use the Nublexa Tablet

When using Nublexa Tablet, it is essential to follow your doctor's instructions carefully. Take the prescribed dose of Nublexa Tablet with food as advised by your doctor. It is important to swallow the tablet whole with a glass of water and not chew, crush, or break it. Typically, NUBLEXA 40MG TABLET 28'S should be taken once daily for 21 days, followed by a break of 7 days. This cycle constitutes one round of therapy. Repeat this cycle as recommended by your doctor. It is crucial not to exceed the prescribed dose of the medicine. Remember to take Nublexa Tablet consistently and seek guidance from your healthcare provider if you have any concerns.


Uses of Nublexa Tablet

Nublexa Tablet is used in the treatment of colorectal cancer, which specifically involves cancer of the colon and rectum. This medication is prescribed to help patients battle this type of cancer.


What conditions Nublexa Tablet treats?

Nublexa Tablet is used to treat colorectal cancer, a condition where cancer cells grow uncontrollably in the colon or rectum. Symptoms include diarrhoea, constipation, bloody stools, changes in bowel habits, and abdominal discomfort.


Should you consult a doctor?

If you experience any side effects such as infection, low blood platelets, anemia, rash, weakness, vomiting, pain, nausea, fever, diarrhea, high blood pressure, decreased appetite, mucosal inflammation, stomatitis, increased liver enzymes, weight loss, voice change, or bilirubin in urine while taking Nublexa Tablet, it is important to inform your doctor. Regular blood tests are necessary to monitor your blood cells and liver function. If you are concerned about persistent side effects, consult your healthcare provider. It is crucial to communicate all medications you are taking to your healthcare team as interactions can occur. Avoid using this medicine during pregnancy or while breastfeeding, and use effective contraception during treatment to prevent pregnancy. Stick to the prescribed dosage and timing advised by your doctor to maximize benefits and minimize the risk of serious side effects.


Side effects of Nublexa Tablet

When taking Nublexa Tablets, some individuals may experience side effects, although most of these effects do not typically necessitate medical attention and tend to diminish as the body adapts to the medication. It is advisable to consult with your doctor if any of these side effects persist or if you have concerns about them. Potential side effects may include infections, low blood platelets, anemia (a low number of red blood cells), skin rash, weakness, vomiting, pain, nausea, fever, diarrhea, high blood pressure, decreased appetite, mucosal inflammation, stomatitis (inflammation of the mouth), tiredness, chest pain, dizziness, increased liver enzymes, weight loss, voice change, and the presence of bilirubin in urine. Specific symptoms such as nausea, diarrhea, loss of appetite, skin rash, hoarseness, tiredness, chest pain, dizziness, and weakness may also occur.


Safety advice

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liver

When using Nublexa Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment, so it's vital to consult your doctor before starting this medication. Regular monitoring of liver function tests is recommended while taking Nublexa Tablet to ensure your liver health is maintained. Patients with severe liver disease are advised against using Nublexa Tablet. If you have any concerns regarding your liver health, make sure to seek guidance from your healthcare provider.

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kidney

Nublexa Tablet is considered safe for use in patients with kidney disease. No dose adjustment is necessary. However, there is limited information on its use in patients with severe kidney disease.

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alcohol

Consult your doctor when consuming alcohol with Nublexa Tablet.

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driving

When taking Nublexa Tablet, avoid driving if you notice any symptoms that may impact your focus and reaction time. It's uncertain if Nublexa Tablet affects driving ability.

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pregnancy

Nublexa Tablet should not be used during pregnancy due to the known risk to the developing baby. Only in life-threatening situations, a doctor may consider prescribing it if benefits outweigh risks. Always consult your doctor.

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breastfeeding

Caution is advised when using Nublexa Tablet while breastfeeding as it may be unsafe. Limited data suggests the drug could pass into breastmilk, potentially harming the baby.


Consumption warning before consuming Nublexa Tablet

Before consuming Nublexa 40mg Tablet 28's, please be aware of the following precautions. Do not take this medicine if you have allergies to it or any of its ingredients. Nursing mothers should stop breastfeeding while on this medication as it can pass into breast milk and pose risks to the infant. It is not suitable for children under 18 years old due to unknown safety and efficacy. Potential side effects may include hypertension, heart attack, skin reactions, gastrointestinal issues, bleeding, liver problems, and Reversible Posterior Leukoencephalopathy Syndrome (RPLS). It is crucial to disclose your full medical history and current medications to the doctor before starting this treatment. If you are pregnant or planning to become pregnant, consult your doctor as this medicine can harm the developing fetus. Additionally, be cautious while driving or operating machinery as Nublexa may cause dizziness.


Related lab tests

Related Lab Tests:
When taking Nublexa Tablet, it is important to monitor certain lab tests to help manage your health. One of the key lab tests to consider is the Carcino Embryonic Antigen (CEA) test. This test measures the levels of CEA in the blood, which is a protein that may be elevated in certain types of cancer, such as colorectal cancer. Monitoring CEA levels can help track the progress of cancer treatment and detect any recurrence. Additionally, other relevant lab tests to consider while on Nublexa Tablet may include liver function tests, complete blood count (CBC), and any other tests recommended by your healthcare provider. Regular monitoring of these lab tests can provide valuable information about your health status and help ensure the effectiveness and safety of Nublexa Tablet treatment.


Additional Information

Habit FormingNo
Chemical ClassDiarylethers Derivative
Therapeutic Class-
Action ClassTyrosine kinase inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025