Neotrexate 5mg Tablet

By Neotrexate

Rx

10 Tablet in a Strip

Composition icon

Composition

Methotrexate(5mg)

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd icon

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd

Dr. Annie Besant Road, Mumbai - 400 030

Expires on or after icon

Expires on or after

April, 2027

About Neotrexate 5mg Tablet

Neotrexate 5mg Tablet is a medication used in the treatment of cancer affecting various areas of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also prescribed for conditions like rheumatoid arthritis, severe psoriasis, and Crohn’s disease. Neotrexate 5mg Tablet can be taken alone or in combination with other medications, and it is crucial to follow your doctor's instructions precisely to avoid potential serious side effects. It may take some time before you start noticing the benefits of the medication, so do not discontinue its use without consulting your doctor.

It is recommended to abstain from alcohol consumption while on Neotrexate 5mg Tablet treatment to prevent liver damage. Common side effects of this medication include ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal discomfort. Your healthcare provider may suggest taking folic acid to alleviate some of these side effects. If any side effects persist or worsen, inform your doctor promptly. Neotrexate 5mg Tablet can lower your body's ability to fight infections and may impact your blood, liver, or kidneys, so regular monitoring through tests like blood tests, X-rays, and physical examinations is necessary during the treatment period.

Before starting Neotrexate 5mg Tablet, disclose to your doctor any existing stomach, liver, or kidney issues, as well as any ongoing medication for infections. The medication may interact with other drugs, so informing your healthcare team about all your current medications is essential. It is not advisable to take Neotrexate 5mg Tablet during pregnancy or while breastfeeding due to potential harm to the baby. Neotrexate 5mg Tablet belongs to the class of medicines known as anti-metabolites and immunosuppressants and is effective in treating conditions like active rheumatoid arthritis, severe psoriasis, severe psoriatic arthritis, breast cancer, lung cancer, blood cancer, and lymphomas. Methotrexate, the active ingredient in Neotrexate 5mg Tablet, works by interfering with the immune system processes that cause inflammation, reducing pain and inflammation, and slowing down joint damage. Additionally, it inhibits the growth of cancer cells, aiding in cancer treatment.

While taking Neotrexate 5mg Tablet, be aware of potential side effects like nausea, vomiting, fatigue, dizziness, and decreased resistance to infections. It is important to adhere to the prescribed dosage to avoid serious toxic effects. Driving should be avoided if experiencing dizziness or fatigue due to the medication. Regular blood tests, kidney, and liver assessments may be required to monitor your health status during the treatment. To prevent any unpleasant drug interactions or side effects, inform your doctor about all your medications and health conditions before starting Neotrexate 5mg Tablet.


Benefits

Neotrexate 5mg Tablet provides several benefits across different medical conditions. In the treatment of cancer, this medication works by slowing the growth of cancer cells in the body. It is effective against a variety of cancers including acute leukemias, non-Hodgkin's lymphoma, and solid tumors found in various organs like breast, lung, bladder, head and neck, as well as cervical, ovarian, and testicular cancer. Neotrexate 5mg Tablet can be used alone or in combination with other drugs, offering a comprehensive approach to cancer treatment. However, due to its potency and toxicity, it is crucial to have a discussion with your doctor about the risks and benefits associated with this medication. Additionally, it is recommended to avoid alcohol consumption and stay hydrated by drinking plenty of water during the treatment.


Moreover, in the treatment of rheumatoid arthritis, Neotrexate 5mg Tablet is a valuable option for patients with severe rheumatoid arthritis who have not responded well to other treatments. Belonging to a group of medicines known as antimetabolites, this drug works by suppressing the body's immune system, thereby reducing inflammation, pain, stiffness, and improving overall joint function. It should be taken exactly as prescribed by the healthcare provider to maximize its benefits. It may take some time, typically several months, for the medication to reach its full effectiveness.


Furthermore, for individuals with severe psoriasis, Neotrexate 5mg Tablet can be used when other treatments have proven insufficient. Psoriasis is a skin condition characterized by the rapid growth of skin cells. This medication functions by targeting and eliminating these overactive cells. As with other conditions, it is crucial to follow the prescription strictly, not exceeding the recommended dosage. Patients are advised to abstain from alcohol consumption and maintain proper hydration throughout the treatment period.


Additionally, in the management of Crohn’s disease, a chronic inflammatory condition of the intestines, Neotrexate 5mg Tablet plays a vital role in reducing inflammation, alleviating symptoms such as diarrhea and abdominal pain, and preventing disease flare-ups. By addressing the underlying inflammation, this medication helps enhance the quality of life for individuals living with Crohn’s disease.


How to use the Neotrexate 5mg Tablet

To use Neotrexate 5mg Tablet, it is important to follow your doctor's instructions regarding the dose and duration of the medication. Swallow the tablet whole with a glass of water, and do not chew, crush, or break it. You can take Neotrexate 5mg Tablet with or without food, but it is recommended to take it at the same time each day for best results. Make sure to take the medication exactly as prescribed by your doctor to ensure its effectiveness in managing your condition.


Uses of Neotrexate 5mg Tablet

Neotrexate 5mg Tablet is commonly used in the treatment of various conditions. It is effective in managing cancer, rheumatoid arthritis, psoriasis, and Crohn’s disease. For cancer patients, Neotrexate 5mg Tablet can help in combating the growth and spread of cancer cells. It is also beneficial for individuals dealing with rheumatoid arthritis as it aids in reducing inflammation and pain in the joints, improving overall quality of life. In cases of psoriasis, this tablet can help in controlling and managing the symptoms of the skin condition, providing relief to those affected. Moreover, for individuals with Crohn’s disease, Neotrexate 5mg Tablet can be beneficial in managing the symptoms and minimizing flare-ups of this inflammatory bowel disease.


What conditions Neotrexate 5mg Tablet treats?

Neotrexate 5mg Tablet is prescribed for treating cancer in different parts of the body like breasts, head, neck, lungs, blood, bone, lymph, and uterus. Additionally, it is used for rheumatoid arthritis, severe psoriasis, and Crohn’s disease. It works by slowing the growth of cancer cells, reducing inflammation, and relieving symptoms in these conditions. This medication can be taken alone or in combination with other medicines, but it is crucial to follow your doctor's instructions precisely. Be cautious of side effects like ulcerative stomatitis, hair loss, and low blood cell count, and consult your doctor if they persist or worsen.


Should you consult a doctor?

Seek medical attention if you experience persistent side effects such as ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, or abdominal distress while taking Neotrexate 5mg Tablet. Inform your doctor if these side effects do not improve or worsen over time. Additionally, contact your healthcare provider if you have any concerns about the medication or if you notice any unusual symptoms. It is essential to follow your doctor's guidance closely and undergo recommended tests to monitor any potential effects on your blood, liver, or kidneys. If you have pre-existing stomach, liver, or kidney issues, or are taking other medications, consult your doctor before starting this treatment. This medicine may compromise your immune system, increasing infection risk. Do not use Neotrexate 5mg Tablet during pregnancy or while breastfeeding as it can harm the baby. Prioritize regular communication with your healthcare team to ensure safe and effective use of this medication.


Side effects of Neotrexate 5mg Tablet

When taking Neotrexate 5mg Tablet, some individuals may experience side effects, although most of these effects do not usually require medical attention and may lessen as your body gets used to the medication. It is advisable to consult your doctor if any side effects persist or if you have concerns about them. Possible side effects of Neotrexate 5mg Tablet include ulcerative stomatitis, which refers to inflammation and sores in the mouth, nausea, abdominal pain, increased liver enzymes, hair loss, and a decrease in blood cells which includes red cells, white cells, and platelets. If you notice any of these side effects or if they become bothersome, it is important to discuss them with your healthcare provider.


Safety advice

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liver

When using Neotrexate 5mg Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require dose adjustments when taking Neotrexate 5mg Tablet. It is advised to consult your doctor for guidance on the proper usage of the medication in such cases.

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kidney

Neotrexate 5mg Tablet requires caution in patients with kidney disease. Dose adjustment may be necessary; consult your doctor. Regular kidney function tests are recommended during treatment.

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alcohol

It is not safe to drink alcohol while taking Neotrexate 5mg Tablet.

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driving

Do not drive if Neotrexate 5mg Tablet causes decreased alertness, affects vision, or makes you feel sleepy and dizzy.

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pregnancy

Neotrexate 5mg Tablet should not be used during pregnancy due to significant harmful effects to the developing baby based on studies on pregnant women and animals. It is important to seek your doctor's advice regarding its use.

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breastfeeding

Neotrexate 5mg Tablet is not safe to use while breastfeeding. There is a risk of the drug causing harm to the baby.


Consumption warning before consuming Neotrexate 5mg Tablet

Before consuming Neotrexate 5mg Tablet, it is essential to follow your doctor’s instructions carefully. Taking more than the prescribed dosage can lead to severe side effects. It may take some time for the medication to show its benefits, so do not stop taking it without consulting your doctor. During the treatment with this medication, it is advisable to avoid alcohol consumption as it can increase the risk of liver damage. Common side effects of Neotrexate 5mg Tablet include ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal discomfort. Inform your doctor if these side effects persist or worsen. This medicine may weaken your immune system and affect blood, liver, or kidney functions. Regular monitoring through tests like blood tests and X-rays is necessary to detect any potential issues. Prior to starting this treatment, disclose any stomach, liver, or kidney problems to your doctor, and inform them of all medications you are taking to avoid interactions. Neotrexate 5mg Tablet is not recommended during pregnancy or breastfeeding as it may harm the baby.


What if you forgot to take Neotrexate 5mg Tablet?

If you forget to take a dose of Neotrexate 5mg Tablet, try to take it as soon as you remember. But, if it's nearly time for your next scheduled dose, it's best to just skip the missed one and continue with your usual dosing routine. Avoid taking a double dose to make up for the missed one.


Related lab tests

When taking Neotrexate 5mg Tablet, it is important to monitor certain lab tests to ensure your health and the effectiveness of the medication. Related lab tests that may be done include Anti Saccharomyces Cerevisiae (ASCA) tests, which check for specific antibodies in the blood that can indicate conditions such as Crohn's disease or ulcerative colitis. These tests are available in two types: IgA and IgG. Another test to consider is the Rheumatoid Factor test, which measures the amount of rheumatoid factor in the blood. This test can help in diagnosing conditions like rheumatoid arthritis. The Rheumatoid Factor test is available in two methods: Agglutination and Turbidometry. Additionally, the Rheumatoid Factor IgG Antibody test can also be beneficial in diagnosing certain autoimmune diseases. These lab tests are important for monitoring your health while taking Neotrexate 5mg Tablet.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolite- Methotrexate

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024