Mezakool 400mg Tablet
By Mezakool
Rx
10 Tablet in a Strip

Composition
Mesalazine(400mg)

Manufacturer - Alembic Pharmaceuticals Ltd
Alembic Road, Vadodara - 390 003, Gujarat,INDIA

Expires on or after
May, 2026
About Mezakool 400mg Tablet
Mezakool 400mg Tablet is an anti-inflammatory medicine primarily used in the treatment of ulcerative colitis, a type of bowel disease that causes symptoms like diarrhea, bleeding, and stomach pain due to inflammation in the bowel. This medication can also be prescribed for the management of Crohn’s ileocolitis, another bowel disease. It is important to take Mezakool 400mg Tablet with food, and the dosage will be determined by the specific condition being treated. It is crucial to follow your doctor's instructions carefully to maximize the effectiveness of the treatment.
Continuing the prescribed course of treatment is essential because stopping Mezakool 400mg Tablet prematurely can lead to a recurrence of symptoms and potentially worsen the underlying condition. Common side effects may include nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. If these side effects persist or worsen, it is vital to inform your doctor. In rare cases, a severe allergic reaction may occur, necessitating immediate medical intervention. Symptoms such as swelling of the face, tongue, throat, unusual bleeding, rash, fever, sore throat, or excessive tiredness should be reported promptly to your healthcare provider.
Prior to taking Mezakool 400mg Tablet, it is important to disclose any existing kidney or liver issues, as well as any stomach blockages. Age and other medications being taken should also be discussed with your doctor, as they may impact the suitability and effectiveness of this medication. Pregnant or breastfeeding individuals should seek medical advice before using this medication. It is crucial to inform your doctor about all other medications you are currently taking, as some may interact with Mezakool 400mg Tablet.
Benefits
Mezakool 400mg Tablet, containing Mesalamine, is a beneficial medication for individuals suffering from ulcerative colitis and Crohn's disease. In ulcerative colitis, a condition affecting the large intestine and rectum, this tablet can effectively alleviate symptoms such as redness, swelling, bleeding, diarrhea, and abdominal pain. By reducing inflammation in the intestines, Mezakool 400mg Tablet provides relief from discomfort and helps in preventing the recurrence of these distressing symptoms. It is important to take this medication regularly as prescribed by your doctor to maximize its effectiveness. Additionally, staying well hydrated by drinking plenty of fluids while on this treatment is recommended.
For individuals with Crohn's disease, a long-term inflammatory condition of the intestines, Mezakool 400mg Tablet is beneficial in managing symptoms like abdominal pain and diarrhea. This medication works by inhibiting the production of certain chemicals that contribute to pain and swelling, thereby reducing inflammation and providing relief to patients. Furthermore, Mezakool 400mg Tablet may play a preventive role in stemming future episodes of ulcerative colitis, offering a comprehensive approach to managing these chronic conditions. Overall, the anti-inflammatory properties of Mesalamine in Mezakool 400mg Tablet make it an effective treatment option for individuals looking to alleviate the symptoms of ulcerative colitis and Crohn's disease, ultimately enhancing their quality of life.
How to use the Mezakool 400mg Tablet
To make the most of Mezakool 400mg Tablet, follow your doctor's instructions on dosage and duration carefully. Swallow the tablet whole with a glass of water. Do not chew, crush, or break it. You can take this medication with or without food, but it's recommended to take it at the same time each day. If you are using the orally disintegrating tablet, place it in your mouth and let it dissolve completely without swallowing or chewing. For granules, empty them on your tongue and drink water or orange juice, or mix with yogurt and take immediately without chewing. Always refer to the label and your doctor's guidance for the best way to use the pellets. Remember, your doctor will determine the appropriate dose and duration based on factors like your age, weight, and medical condition. If you have any questions or concerns about how to use Mezakool 400mg Tablet, don't hesitate to consult your healthcare provider for clarification.
Uses of Mezakool 400mg Tablet
Mezakool 400mg Tablet is commonly used to treat and prevent mild to moderate cases of ulcerative colitis and Crohn’s disease. These conditions can cause symptoms like diarrhea, rectal bleeding, and stomach pain. By using Mezakool 400mg Tablet, patients can experience a reduction in these uncomfortable symptoms associated with ulcerative colitis. This medication is effective in managing the symptoms of these bowel disorders and can improve the quality of life for individuals affected by ulcerative colitis and Crohn’s disease.
What conditions Mezakool 400mg Tablet treats?
Mezakool 400mg Tablet is used to treat ulcerative colitis and Crohn's disease. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the colon, leading to symptoms like bloody stools, stomach pain, and diarrhoea. Crohn's disease is another chronic inflammatory bowel disease that can affect different parts of the gastrointestinal tract. This condition presents symptoms such as blood in stools, stomach cramps, and fatigue. Mezakool 400mg Tablet helps manage these conditions by reducing inflammation and improving symptoms.
Should you consult a doctor?
If you have a history of stomach or gut narrowing/blockage, it is important to consult your doctor before taking Mezakool 400mg Tablet. Additionally, if the medicine is being considered for use in children or adolescents under 18 years old, it is advisable to first consult a doctor due to the limited information available on its safety and effectiveness in this age group. It is important to seek medical advice to ensure the appropriate and safe use of Mezakool 400mg Tablet in these specific situations.
Side effects of Mezakool 400mg Tablet
The side effects of Mezakool 400mg Tablet may include stomach pain or epigastric pain, flatulence (gas), headache, vomiting, diarrhea, nausea, abdominal pain, and rash. In some cases, individuals may also experience bleeding and bruising, feeling sleepy, tired, or dizzy, trembling or shaking, muscle pain, hair loss, ear pain, throat pain, a racing heartbeat, inflammation of the pancreas with symptoms like upper abdominal pain, nausea, and back pain, rectal polyps with symptoms such as constipation and bleeding, acne, red itchy welts, swollen face, indigestion, bloating, joint pain, back pain, changes in blood pressure, itching, and rash. More severe side effects may include kidney failure, increased susceptibility to infections due to decreased white blood cell count, and photosensitivity (heightened skin sensitivity to sun and ultraviolet light). It is crucial to immediately discontinue the use of Mezakool 400mg Tablet and seek medical attention if any serious reactions occur, such as Stevens-Johnson syndrome or toxic epidermal necrolysis, acute intolerance syndrome symptoms like severe stomach pain, bloody diarrhea, fever, and rash, unexplained bruising, signs of allergic reactions like swelling of tongue, lips, or eyes, and signs of increased pressure in the brain indicated by various symptoms like headache and blurred vision.
Safety advice

liver
When taking Mezakool 400mg Tablet, it's important to be cautious if you have liver disease. Patients with liver issues may require a dosage adjustment when using Mezakool 400mg Tablet. It is advised to consult with your doctor regarding the use of this medication to ensure it is safe and appropriate for your liver condition.

kidney
Mezakool 400mg Tablet requires caution in patients with kidney disease. Dosage adjustment may be necessary, and it's not recommended for those with severe kidney disease. Consult with your doctor for guidance.

alcohol
Caution is advised when consuming alcohol with Mezakool 400mg Tablet. Consult your doctor.

driving
Mezakool 400mg Tablet typically does not impact your driving ability.

pregnancy
Mezakool 400mg Tablet may not be safe to use during pregnancy as animal studies have shown harmful effects on the developing baby. Your doctor will consider the benefits and risks before prescribing it to you. Please consult your doctor before using.

breastfeeding
Mezakool 400mg Tablet may not be safe during breastfeeding. Limited data shows it can pass into breastmilk and harm the baby. If taking this medication, watch for diarrhea in your baby.
Age above 75(Geriatrics)
Consumption warning before consuming Mezakool 400mg Tablet
Before consuming Mezakool 400mg Tablet, ensure to inform your doctor about any allergies to its ingredients. Use caution if you are elderly, pregnant, or breastfeeding. Avoid this medication in case of severe kidney failure. Some individuals may experience severe skin reactions like toxic epidermal necrolysis or Stevens-Johnson syndrome while using Mezakool 400mg Tablet, which requires immediate medical attention. Discontinue the tablet and consult a doctor if you encounter stomach pain, cramps, severe headache, fever, or rash. Refrain from taking this medication if you have previously had adverse reactions or kidney issues with medications like Sulphasalazine. It is advisable to seek medical advice promptly for any concerning symptoms while on Mezakool 400mg Tablet.
Disease interactions
When it comes to disease drug interactions with Mezakool 400mg Tablet, there are some key considerations to keep in mind. If you have a stomach ulcer, a stomach blockage, asthma, or any condition that may lead to bleeding or affect your liver, kidneys, or blood, it is important to inform your doctor before starting this medication. This is crucial for your safety and to ensure that the medication will be effective for your specific health needs. By discussing your medical history and conditions with your healthcare provider, they can determine if Mezakool 400mg Tablet is the right choice for you and if any adjustments need to be made to your treatment plan. It is always advisable to be transparent about your health status to receive the best possible care and outcomes when taking any medication.
What if you forgot to take Mezakool 400mg Tablet?
If you forget to take your scheduled dose of Mezakool 400mg Tablet, try to take it as soon as you remember. But, if it's nearly time for your next dose, just skip the missed one and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. This ensures you maintain the correct dosage regimen as prescribed for your treatment. If you need any further clarification on missed doses or dosage adjustments, it's best to consult your healthcare provider for guidance.
What happens if you take overdose of Mezakool 400mg Tablet?
If someone takes more than the recommended amount of Mezakool 400mg Tablet, it is considered an overdose. In case of an overdose, it is important to seek immediate medical help by going to the nearest hospital or contacting your doctor right away. Symptoms of overdosage may include ringing in the ears (tinnitus), dizziness, headache, confusion, drowsiness, shortness of breath, excessive fluid loss due to sweating, diarrhea, and vomiting, feeling lightheaded due to low blood sugar, rapid breathing, and/or fever. If you or someone you know shows signs of overdose after taking Mezakool 400mg Tablet, it is crucial to act promptly to ensure proper medical attention and care.
Related lab tests
Related Lab Tests:
When taking Mezakool 400mg Tablet, it is important to monitor certain lab tests to ensure that your body is responding well to the medication. The following lab tests are recommended for patients using Mezakool 400mg Tablet:
1. Anti Neutrophilic Cytoplasmic Antibody (ANCA) - This test helps in diagnosing certain autoimmune diseases.
2. Anti Saccharomyces Cerevisiae Antibodies (ASCA), IgA and IgG - These tests are used to detect antibodies associated with conditions like Crohn's disease.
3. C-Reactive Protein Quantitative - This test measures the level of inflammation in the body.
4. Erythrocyte Sedimentation Rate (ESR) - This test helps in determining the presence of inflammation or infection in the body.
5. Colonoscopy - A procedure to examine the colon and rectum for abnormalities or signs of disease.
6. Sigmoidoscopy - An examination of the lower part of the colon to detect issues such as polyps, inflammation, or cancer.
Regular monitoring of these lab tests can help in assessing the effectiveness of Mezakool 400mg Tablet and ensuring your health is being managed appropriately.
Additional Information
| Habit Forming | No |
| Chemical Class | Aminosalicylic Acids Derivative |
| Therapeutic Class | - |
| Action Class | 5- Aminosalicylic acid (5-ASA) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹62.35
₹67.77
8% OFF
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024
