MEXATE 7.5 MG INJECTION
By Mexate
Rx
1ml Injection in a Vial

Composition
Methotrexate(7.5mg)

Manufacturer - Zydus Cadila
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after
October, 2025
About MEXATE 7.5 MG INJECTION
MEXATE 7.5 MG INJECTION is a medication commonly utilized in the management of various health conditions. It is notably employed in the treatment of rheumatoid arthritis, a condition that causes joint inflammation and can lead to damage if left untreated. Furthermore, this medication is effective in addressing severe forms of psoriasis, a skin disease characterized by red, scaly patches on the skin. In addition, MEXATE 7.5 MG INJECTION is employed in the treatment of certain cancers and Crohn's disease.
This medication is to be administered under the supervision of a healthcare professional and should not be self-administered. The dosage and frequency of MEXATE 7.5 MG INJECTION will be determined by your doctor based on the specific condition being treated. It may be prescribed as a standalone treatment or in combination with other medications. It is crucial to adhere to the prescribed dosage regimen as improper use or overconsumption can result in severe side effects. While the therapeutic effects of MEXATE 7.5 MG INJECTION may not be immediate, it is important to continue the treatment as advised by your doctor.
Common side effects associated with this medication include abdominal discomfort, indigestion, loss of appetite, nausea, fatigue, hair loss, and decreased blood platelets. Your doctor may recommend supplementation with folic acid to manage some of these side effects. If these side effects persist or worsen, it is essential to inform your healthcare provider. MEXATE 7.5 MG INJECTION is a potent medication that may lead to serious side effects such as increased susceptibility to infections and complications affecting the blood, liver, or kidneys. Regular monitoring through blood tests is typically recommended during treatment.
Prior to initiating treatment with MEXATE 7.5 MG INJECTION, inform your doctor about any existing medical conditions, pregnancy status, and current medications, especially those used to treat infections. It is crucial to disclose all medications in use to prevent potential interactions. This medication is contraindicated during pregnancy and breastfeeding due to potential harm to the baby. It is advisable to avoid pregnancy for a specified duration after completing treatment with MEXATE 7.5 MG INJECTION. Your healthcare provider may conduct various tests before and during treatment to ensure safe administration of this medication.
Benefits
MEXATE 7.5 MG INJECTION offers beneficial effects for those suffering from rheumatoid arthritis or severe psoriasis. This medication, classified as an antimetabolite, is used when other treatments have been unsuccessful. In the case of rheumatoid arthritis, MEXATE 7.5 MG INJECTION helps by reducing the body's immune response, resulting in decreased swelling, pain relief, improved flexibility, and enhanced overall functionality. It is essential to adhere to the prescribed dosage and duration to maximize its effectiveness. While it is not a first-line treatment, the medication can provide significant relief for those with severe rheumatoid arthritis.
For individuals with severe psoriasis, MEXATE 7.5 MG INJECTION works by targeting and eliminating rapidly growing skin cells associated with the condition. It is crucial to discuss the risks and benefits with a healthcare provider due to its potent and potentially toxic nature. Similar to its usage for rheumatoid arthritis, following the prescribed dosage and duration is key to reaping the full benefits of this treatment. It is important to note that the medication may take some time to reach its full effectiveness, often requiring several months of consistent use.
Moreover, it is advised to avoid alcohol consumption during the course of this treatment and stay hydrated by drinking plenty of water. By following these guidelines and working closely with a healthcare provider, individuals can experience the positive impact of MEXATE 7.5 MG INJECTION in managing their rheumatoid arthritis or severe psoriasis symptoms effectively and improving their quality of life.
How to use the MEXATE 7.5 MG INJECTION
When using MEXATE 7.5 MG INJECTION, it's important to remember that you should never try to administer the injection to yourself. Only a healthcare professional, such as a doctor or a nurse, should give you this medication. The injection will be given into a muscle (intramuscularly) based on specific factors like your age, weight, and the condition being treated. Your doctor will determine the right dosage and how often you should receive the injection. So, trust your healthcare provider to handle the administration of MEXATE 7.5 MG INJECTION for your safety and optimal treatment outcomes.
Uses of MEXATE 7.5 MG INJECTION
MEXATE 7.5 MG INJECTION is utilized in the effective treatment of various conditions such as rheumatoid arthritis, psoriasis, cancer, and Crohn's disease. Specifically, it is used in the management of active rheumatoid arthritis in adults, severe arthritis of unknown causes (idiopathic and juvenile) that does not respond to traditional pain relief medications, psoriasis, Crohn's disease, and polyarthritic forms. Moreover, MEXATE 7.5 MG INJECTION also plays a crucial role in addressing certain types of cancer, including acute lymphocytic lymphoma and meningeal leukemia. These types of cancer can affect various parts of the body such as the ovary, breast, cervix, lungs, bones, and bladder.
What conditions MEXATE 7.5 MG INJECTION treats?
MEXATE 7.5 MG INJECTION is used to treat rheumatoid arthritis, preventing further joint damage. It is also effective for severe psoriasis, certain cancers, and Crohn's disease. This medication reduces immune system activity, easing swelling, pain, and stiffness. Take it as prescribed to see benefits, usually after several months. Side effects like abdominal pain, nausea, and tiredness are common. Regular blood tests are required due to potential serious effects on blood, liver, and kidneys. Avoid alcohol, and inform your doctor of any concerns or persistent side effects. It's crucial to follow all medical advice closely.
Should you consult a doctor?
If you experience any of the following conditions or situations, it is important to seek advice from a doctor before receiving MEXATE 7.5 MG INJECTION: blood disorders, impaired immune system, severe infection like tuberculosis or HIV, ulcers in the gastrointestinal tract, undergoing vaccinations with live vaccines, bone marrow suppression, specific immunodeficiency syndromes, upcoming surgery requiring anesthesia, ulcerative colitis with bowel bleeding, malnourishment. Additionally, inform your doctor if you have diabetes, are overweight, tooth infection like abscess, abnormal bleeding/bruising tendencies, folate deficiency, or undergoing radiotherapy.
Side effects of MEXATE 7.5 MG INJECTION
MEXATE 7.5 MG INJECTION may cause various side effects. Some common side effects include abdominal pain, indigestion, loss of appetite, nausea, vomiting, tiredness, mouth sores, and low blood platelets which usually subside as your body gets used to the medication. Other possible side effects include hair loss, confusion, depression, fits, inflammation of blood vessels, liver disorders, diabetes, and sensitivity to light. Additionally, it may lead to joint or muscle pain, porous bones (osteoporosis), painful urination, severe allergic reactions, eating disorders resulting in weight loss, pain in the chest, cough, nose bleeding, and more. Serious side effects that require immediate medical attention include sudden bleeding from the lungs, general weakness, dry cough, severe skin peeling or blisters, unusual bleeding or bruising, presence of ulcers in the mouth, black stools, yellowing of skin and eyes, seizures, blurred vision, swelling of hands or face, and symptoms of infection like fever and body ache. If you experience any severe reactions, stop using the injection and consult your doctor promptly.
Safety advice

liver
When using MEXATE 7.5 MG INJECTION, it is important to exercise caution if you have liver disease. Patients with liver issues may require a dose adjustment of MEXATE 7.5 MG INJECTION, so it's crucial to consult your doctor before starting this medication. It is advised not to use MEXATE 7.5 MG INJECTION in patients with severe liver disease to avoid any potential complications. Always prioritize the guidance of your healthcare provider when considering this injection in relation to liver health.

kidney
MEXATE 7.5 MG INJECTION requires caution in patients with kidney disease. Dosage may need adjustment and regular kidney function monitoring is recommended. Consult your doctor for proper guidance.

alcohol
Caution is advised when drinking alcohol while using MEXATE 7.5 MG INJECTION. It is recommended to consult with your doctor regarding alcohol consumption.

driving
To ensure safety, do not drive if you experience reduced alertness, vision changes, drowsiness, or dizziness while using MEXATE 7.5 MG INJECTION.

pregnancy
MEXATE 7.5 MG INJECTION should be avoided during pregnancy. Studies on pregnant women and animals have shown potential harmful effects on the developing baby. Seek advice from your doctor before using this medication.

breastfeeding
Caution is advised when using MEXATE 7.5 MG INJECTION while breastfeeding as it may pose a risk of toxicity to the baby. It is better to consult your doctor before using MEXATE 7.5 MG INJECTION.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming MEXATE 7.5 MG INJECTION
Before consuming MEXATE 7.5 MG INJECTION, it is crucial to understand some important warnings. This medication is primarily used to treat conditions like rheumatoid arthritis, psoriasis, certain cancers, and Crohn's disease. It should only be administered under the supervision of a healthcare professional like a doctor or nurse and should not be self-administered. The dosage and frequency of administration will be determined by your doctor based on your specific condition, and it is essential to follow their instructions precisely to avoid serious side effects.
Common side effects of MEXATE 7.5 MG INJECTION may include abdominal pain, indigestion, loss of appetite, nausea, and tiredness among others. If these side effects persist or worsen, it is important to inform your doctor. This medication can also affect your body’s ability to fight infections and may lead to issues with your blood, liver, or kidneys. Regular blood tests will be recommended by your doctor to monitor for these potential risks.
Moreover, it is crucial to avoid consuming alcohol while on this medication as it may increase the risk of liver damage. Before starting treatment with MEXATE 7.5 MG INJECTION, inform your doctor if you are pregnant, have existing health conditions, or are taking other medications. This medicine is not recommended during pregnancy or breastfeeding due to potential harm to the baby. Additionally, precautions should be taken to avoid conception for a period after treatment has ceased. Regular monitoring and tests will be conducted throughout the treatment period to ensure your safety and well-being.
What happens if you take overdose of MEXATE 7.5 MG INJECTION?
In the case of MEXATE 7.5 MG INJECTION, it is important to note that this medication is usually administered by healthcare professionals in a hospital setting, minimizing the risk of an overdose. However, if you do experience any unusual symptoms such as increased bruising or bleeding, nausea, vomiting, weakness, mouth sores, black or bloody stools, coughing up blood, or reduced urination, it is vital to contact your doctor immediately. These symptoms could indicate a potential overdose, and prompt medical attention is necessary to address any concerns promptly.
Related lab tests
When using MEXATE 7.5 MG INJECTION, it is important to monitor certain lab tests to ensure your health is maintained. The following related lab tests may be advised by your healthcare provider:
1. Anti Saccharomyces Cerevisiae (ASCA), IgA
2. Anti Saccharomyces Cerevisiae (ASCA), IgG
3. Rheumatoid Factor - Agglutination
4. Rheumatoid Factor - Turbidometry
5. Rheumatoid Factor IgG Antibody
Moreover, monitoring your overall health is crucial. You may also need to undergo the following lab tests:
1. Complete Blood Count (CBC)/ Hemogram
2. Liver Function Test (LFT)
3. Kidney Function Test (KFT)
These tests help your healthcare provider assess the impact of MEXATE 7.5 MG INJECTION on your body and ensure that the medication is benefiting you without causing any harm. Regular monitoring through these lab tests can provide valuable information about your health status.
Additional Information
Habit Forming | No |
Chemical Class | Glutamic Acid Derivatives |
Therapeutic Class | ANTI NEOPLASTICS |
Action Class | Antimetabolite- Methotrexate |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹30
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024