MEXATE 25 MG INJECTION
By Mexate
Rx
1ml Injection in a Vial

Composition
Methotrexate(25mg)

Manufacturer - Zydus Cadila
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after
October, 2025
About MEXATE 25 MG INJECTION
MEXATE 25 MG INJECTION is a medication primarily used for treating rheumatoid arthritis to help prevent further damage to the joints. It is also prescribed for severe forms of psoriasis, various cancers, and Crohn's disease. This injection is administered under the supervision of a healthcare professional and should not be self-administered. It can be used alone or in combination with other medications as determined by your doctor. The dosage and frequency of MEXATE 25 MG INJECTION will be decided by your doctor based on your specific condition and may be adjusted over time. It is crucial to follow your doctor's instructions precisely to avoid serious side effects.
One essential point to remember is that the benefits of MEXATE 25 MG INJECTION may not be immediately apparent, and it could take several weeks to months before improvements are noticed. It is important not to stop treatment unless advised by your doctor. Alcohol consumption while using this medication should be avoided as it can increase the risk of liver damage.
Common side effects of MEXATE 25 MG INJECTION include abdominal pain, indigestion, loss of appetite, nausea, vomiting, fatigue, hair loss, and low blood platelets. Your doctor may recommend taking folic acid to help minimize these side effects. If side effects persist or worsen, it is crucial to inform your doctor. Some individuals may experience severe side effects while taking MEXATE 25 MG INJECTION, which can impact immune function and various organs like the liver, kidneys, or blood. Regular blood tests may be necessary to monitor for these potential issues.
Before starting treatment with MEXATE 25 MG INJECTION, inform your doctor about any existing medical conditions, pregnancy status, or current medications, especially those used to treat infections. It is important to disclose all medications to prevent potential interactions. This medication is not recommended during pregnancy or breastfeeding, as it may harm the baby. It is advised to use contraception and avoid conception for some time after completing the treatment. Your doctor may conduct several tests before and during treatment to ensure its safety and effectiveness.
Benefits
MEXATE 25 MG INJECTION offers several benefits in the treatment of rheumatoid arthritis and psoriasis. In the case of rheumatoid arthritis, this medication is recommended for severe cases where other treatments have been ineffective. By belonging to a group of medicines called antimetabolites, MEXATE 25 MG INJECTION works by reducing the body's immune system. This action helps decrease swelling, alleviate pain, reduce stiffness, and improve overall joint function. It is essential to follow the prescribed dosage strictly and for the recommended duration to achieve the maximum benefit from the treatment. While MEXATE 25 MG INJECTION may not show immediate results, its effectiveness can be experienced fully after several months of consistent use.
For psoriasis treatment, MEXATE 25 MG INJECTION is utilized for severe cases that have not responded to other therapies. Psoriasis is characterized by the rapid growth of skin cells in the body. MEXATE 25 MG INJECTION, being an antimetabolite, functions by eradicating these fast-dividing cells, thus alleviating the symptoms of psoriasis. It is crucial to note that this medication is potent and toxic, necessitating a thorough discussion of the risks and benefits with a medical professional before starting the treatment. Similarly to its application in rheumatoid arthritis, MEXATE 25 MG INJECTION for psoriasis should be taken precisely as prescribed and for the designated duration to achieve optimal outcomes. Drinking alcohol while on this treatment is not recommended, and maintaining proper hydration by consuming an adequate amount of water is advised.
In conclusion, MEXATE 25 MG INJECTION offers significant benefits in managing both rheumatoid arthritis and psoriasis. By understanding its mode of action and following the prescribed guidelines diligently, patients can experience reduced symptoms, improved function, and a better quality of life through this treatment option.
How to use the MEXATE 25 MG INJECTION
To use MEXATE 25 MG INJECTION, it is important to have it administered by your doctor or nurse. Please do not try to use this medicine on your own. Your healthcare provider will determine the correct dosage and method of administration based on your individual condition. Mexate is typically given as an injection into a muscle or a vein. It is important to follow your doctor's instructions carefully during the administration of this medication. If you have any questions or concerns about how MEXATE 25 MG INJECTION is being used, do not hesitate to discuss them with your healthcare provider. It is crucial to ensure the safe and effective use of this medication by following your doctor's guidance.
Uses of MEXATE 25 MG INJECTION
MEXATE 25 MG INJECTION is a versatile medication used in various health conditions. It is commonly prescribed for the treatment of rheumatoid arthritis, a chronic inflammatory disorder affecting the joints. MEXATE 25 MG INJECTION is also effective in managing psoriasis, a skin disease characterized by red, scaly patches. Additionally, this medication plays a crucial role in the treatment of cancer by helping to slow down the growth of cancer cells. Patients with Crohn's disease, a type of inflammatory bowel disease, can benefit from MEXATE 25 MG INJECTION to reduce inflammation and manage symptoms effectively.
What conditions MEXATE 25 MG INJECTION treats?
MEXATE 25 MG INJECTION is used to treat rheumatoid arthritis, a condition that causes joint damage. It can also be effective in treating severe forms of psoriasis, cancers, and Crohn's disease. This medication works by reducing the body's immune response, which helps in reducing swelling, pain, and stiffness. It is important to follow the prescribed dosage and duration to achieve optimal results. Side effects may include abdominal pain, nausea, tiredness, and low blood platelets. Inform your doctor if these side effects persist or worsen. It is crucial to avoid alcohol consumption during treatment to prevent liver damage.
Should you consult a doctor?
If you experience persistent side effects such as abdominal pain, indigestion, loss of appetite, nausea, vomiting, tiredness, mouth sores, low blood platelets, or hair loss while taking MEXATE 25 MG INJECTION, it is important to consult your doctor. It is also crucial to seek medical attention if these side effects worsen or if you have concerns about them. Additionally, if you develop new symptoms or notice any unusual changes in your health, particularly related to your stomach, liver, or kidneys, it is advisable to contact your healthcare provider promptly. MEXATE 25 MG INJECTION may lower your ability to fight infections, so if you suspect any signs of infection or have any other health issues, do not hesitate to reach out to your doctor. Your healthcare team can offer guidance on managing side effects and determine if any further medical intervention is necessary.
Side effects of MEXATE 25 MG INJECTION
When taking MEXATE 25 MG INJECTION, you may experience some side effects. Remember that most side effects are usually temporary and will go away as your body gets used to the medication. If you are concerned or if the side effects persist, it's important to consult your doctor for guidance. Common side effects may include abdominal pain, indigestion, loss of appetite, nausea, vomiting, tiredness, mouth sores, low blood platelets, and hair loss. If you notice any of these side effects, talk to your doctor to address any concerns you may have.
Safety advice

liver
When using MEXATE 25 MG INJECTION, it is important to be cautious if you have liver disease. In such cases, your doctor may need to adjust the dosage of MEXATE 25 MG INJECTION. It is not recommended to use MEXATE 25 MG INJECTION in patients with severe liver disease. It is advisable to consult your doctor for proper guidance regarding the use of MEXATE 25 MG INJECTION in relation to liver issues.

kidney
MEXATE 25 MG INJECTION must be used carefully in patients with kidney disease. Dose adjustment may be required, so consult your doctor. Regular monitoring of kidney function is recommended during treatment.

alcohol
When using MEXATE 25 MG INJECTION, caution is advised when consuming alcohol. It is best to consult with your doctor.

driving
MEXATE 25 MG INJECTION can reduce alertness, impact vision, cause drowsiness, and dizziness. Avoid driving if experiencing these symptoms.

pregnancy
MEXATE 25 MG INJECTION is not safe to use during pregnancy. Studies on pregnant women and animals have found harmful effects on the developing baby. It is important to seek your doctor's advice before using this medication during pregnancy.

breastfeeding
MEXATE 25 MG INJECTION is not recommended during breastfeeding as it may pose a risk of toxicity to the baby.
Consumption warning before consuming MEXATE 25 MG INJECTION
Before consuming MEXATE 25 MG INJECTION, it is crucial to understand important precautions. This medicine is used to treat rheumatoid arthritis, psoriasis, some cancers, and Crohn's disease. It should only be administered by a healthcare professional and not by yourself. The dosage and frequency will be determined by your doctor based on your condition. It is vital to follow your doctor's instructions precisely to avoid serious side effects. Refrain from alcohol consumption as it may harm your liver.
Common side effects include abdominal pain, indigestion, nausea, and fatigue. Your doctor may recommend folic acid to minimize these effects. If side effects persist or worsen, inform your doctor promptly. Mexate is a potent medication and can impact your immune system, blood, liver, and kidneys. Regular blood tests are advised to monitor your health status.
Inform your doctor about pregnancy, existing health conditions, medications, and avoid pregnancy for some time post-treatment. Various tests may be performed before and during treatment. Mexate requires careful handling due to its potential side effects, so follow medical advice diligently.
Related lab tests
Related Lab Tests:
When using MEXATE 25 MG INJECTION, it is important to monitor certain lab tests to ensure the medication is working effectively and not causing any adverse effects. The following lab tests are commonly recommended for patients using MEXATE 25 MG INJECTION:
1. Anti Saccharomyces Cerevisiae (ASCA), IgA: This test helps in diagnosing certain autoimmune diseases like Crohn's disease and ulcerative colitis. It measures the level of IgA antibodies against Saccharomyces cerevisiae, a type of yeast.
2. Anti Saccharomyces Cerevisiae (ASCA), IgG: Similar to the IgA test, this test also detects antibodies against Saccharomyces cerevisiae but specifically measures the IgG antibodies.
3. Rheumatoid Factor - Agglutination and Rheumatoid Factor - Turbidometry: These tests measure the presence of rheumatoid factor in the blood, which is an antibody produced by the immune system in certain autoimmune conditions, like rheumatoid arthritis.
4. Rheumatoid Factor IgG Antibody: This test specifically measures IgG antibodies related to rheumatoid factor, which can indicate the presence and activity of autoimmune diseases like rheumatoid arthritis.
Regular monitoring of these lab tests can help healthcare providers track the response to MEXATE 25 MG INJECTION and adjust treatment accordingly.
Additional Information
Habit Forming | No |
Chemical Class | Glutamic Acid Derivatives |
Therapeutic Class | ANTI NEOPLASTICS |
Action Class | Antimetabolite- Methotrexate |
FAQs
Disclaimer
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024