Metgem 500 Tablet ER
By Metgem
Rx
10 Tablet ER in a Strip

Composition
Metformin(500mg)

Manufacturer - Sun Pharmaceutical Industries Ltd
Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after
April, 2026
About Metgem 500 Tablet ER
Metgem 500 Tablet ER is a medication that is primarily used in the treatment of type 2 diabetes mellitus. Individuals with type 2 diabetes have difficulty in regulating their blood sugar levels, and this medication helps in controlling and managing these levels effectively. By doing so, it also aids in preventing the development of severe complications associated with diabetes. Additionally, this medicine is utilized for the management of Polycystic ovary syndrome (PCOS) in women, a condition related to menstruation.
When taking Metgem 500 Tablet ER, it is advisable to consume it with food to reduce the likelihood of experiencing nausea and abdominal discomfort. Consistency is key with this medication, and it is recommended to take it at the same time daily to maximize its benefits. Discontinuing the medication should only be done under the guidance of a healthcare provider. Emphasizing the importance of maintaining a healthy lifestyle, including following the prescribed diet and exercise regimen, is crucial for effectively managing diabetes alongside taking this medication.
Possible side effects of Metgem 500 Tablet ER may include nausea, vomiting, changes in taste perception, diarrhea, abdominal pain, and decreased appetite. It is essential to monitor blood sugar levels regularly, especially when combining this medication with other antidiabetic drugs, alcohol consumption, or skipping meals, as these factors may lead to hypoglycemia (low blood sugar levels). Individuals with existing kidney, liver, or heart conditions, as well as pregnant or breastfeeding women, should consult their healthcare provider before initiating treatment with this medication.
Metgem 500 Tablet ER is classified as a biguanide, belonging to a group of anti-diabetic medications. It is utilized to lower elevated blood glucose levels in patients with type 2 diabetes by enhancing the body's response to insulin, reducing sugar production in the liver, and delaying sugar absorption in the gastrointestinal tract. This medication is commonly prescribed as first-line therapy for type 2 diabetes when dietary modifications and physical activity alone are insufficient in controlling blood sugar levels.
In addition to its primary use for type 2 diabetes, Metgem 500 Tablet ER also finds off-label application in the management of PCOS, aiding in normalizing menstruation cycles, balancing hormonal levels, lowering blood sugar, and promoting ovulation in affected women. While side effects are generally mild, individuals may experience symptoms such as diarrhea, nausea, vomiting, or a metallic taste in the mouth. Rarely, the occurrence of lactic acidosis, characterized by symptoms like dizziness, drowsiness, and muscle pain, may result from the use of this medication.
The optimal efficacy of Metgem 500 Tablet ER is achieved when complemented with a healthy lifestyle, including weight loss (for individuals with BMI >25), reduced caloric intake, and increased physical activity. It is crucial to maintain open communication with healthcare providers regarding any concerning health conditions or changes experienced while using this medication.
Benefits
Metgem 500 Tablet ER is a medication that belongs to a class of medicines known as biguanides and is specifically designed for the treatment of Type 2 diabetes mellitus. By working to lower glucose production in the liver, delaying the absorption of sugar from the intestines, and increasing the body's sensitivity to insulin, this medication plays a crucial role in managing diabetes and achieving good control of blood sugar levels. By effectively lowering blood glucose levels through its mechanism of action, Metgem 500 Tablet ER helps reduce the risks of potential serious complications associated with diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs.
One of the key advantages of Metgem 500 Tablet ER is that it does not cause a sudden drop in blood glucose levels or significant hypoglycemia, unlike some other anti-diabetic medications like sulfonylureas or insulin. Additionally, Metgem 500 Tablet ER may even lead to modest weight loss instead of weight gain, making it a favorable option for individuals concerned about weight management while managing their diabetes. For individuals in a prediabetic condition, Metgem 500 Tablet ER is the recommended treatment to help prevent the progression to Type 2 diabetes.
Moreover, Metgem 500 Tablet ER offers protective benefits against serious diabetes-related complications, including kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in hands and feet (Diabetic Neuropathy), and the risk of limb amputation. By taking this medication regularly as prescribed, along with maintaining a proper diet and incorporating regular exercise into your routine, you can significantly reduce the likelihood of developing these severe complications. Additionally, Metgem 500 Tablet ER also helps lower the risk of experiencing a heart attack or stroke, further highlighting its importance in managing diabetes and promoting overall health.
In conclusion, Metgem 500 Tablet ER serves as a valuable medication in the management of Type 2 diabetes mellitus by providing multiple benefits, including blood sugar control, prevention of complications, weight management, and overall improvement in insulin sensitivity. When used consistently in conjunction with a healthy lifestyle, Metgem 500 Tablet ER can help individuals lead a normal and healthy life while effectively managing their diabetes.
How to use the Metgem 500 Tablet ER
To use Metgem 500 Tablet ER properly, follow the instructions provided by your doctor. Take the medication in the dose and duration recommended by your doctor. Make sure to swallow the tablet whole without chewing, crushing, or breaking it. It is essential to take Metgem 500 Tablet ER with food.
If you are prescribed Metgem 500 Tablet ER 10's, ensure that you take it with meals to minimize stomach or bowel side effects, or as directed by your doctor. Your doctor will determine how often you should take the tablets based on your specific medical condition. Remember to swallow Metgem 500 Tablet ER 10's with a full glass of water.
For Carbophage XR 500MG Tablet, it is advisable to take it after meals, following your physician's instructions. Swallow the tablet with a glass of water and do not crush or chew it. Your doctor will determine the appropriate dose and duration of therapy depending on factors like your age, body weight, and the medical condition being treated. It is important not to discontinue taking Carbophage XR 500MG Tablet unless your doctor advises you to do so.
Uses of Metgem 500 Tablet ER
Metgem 500 Tablet ER is primarily used for treating Type 2 diabetes mellitus, also referred to as Type II diabetes mellitus. This medication is specifically designed to help manage and control blood sugar levels in individuals diagnosed with Type 2 diabetes. By effectively regulating blood sugar levels, Metgem 500 Tablet ER plays a crucial role in the overall treatment plan for this condition. It is an important tool in helping individuals with Type 2 diabetes maintain a healthier lifestyle and reduce the long-term risks associated with uncontrolled blood sugar levels.
What conditions Metgem 500 Tablet ER treats?
Metgem 500 Tablet ER is used to manage Type 2 diabetes, a long-term condition that impacts how the body processes insulin. This type of diabetes is more common in middle-aged and older individuals and is sometimes referred to as adult-onset diabetes. Symptoms of Type 2 diabetes can include increased thirst, frequent urination, slow wound healing, increased hunger, fatigue, and blurred vision. Patients may also experience weight changes. Complications of Type 2 diabetes can involve nerve issues, kidney problems, eye damage, limb loss, sexual dysfunction, and a higher risk of heart attack or stroke.
Should you consult a doctor?
It is important to seek medical advice when taking Metgem 500 Tablet ER if you have severe, uncontrollable diabetes, lactic acidosis, ketoacidosis, dehydration from vomiting or diarrhea, severe systemic infection, shock, circulation problems, breathing difficulties, or alcoholism. Before starting Metgem 500 Tablet ER, inform your doctor if you are due for an X-ray or scan, planning a major surgery, or fasting. It is crucial to consult a doctor if any of these conditions apply to you to ensure safe and effective use of Metgem 500 Tablet ER.
Side effects of Metgem 500 Tablet ER
When taking Metgem 500 Tablet ER, some side effects may occur. Most side effects are temporary and may go away as your body gets used to the medicine. However, if the side effects persist or you are concerned about them, it is important to consult your doctor. Possible side effects may include digestive issues such as diarrhea, nausea, vomiting, flatulence, stomach pain, and loss of appetite. You may also experience changes in taste, including a metallic taste. These side effects can vary in severity from person to person, so it is important to be mindful of how your body is reacting to the medication. If you experience any of these side effects and are worried, seek medical advice.
Safety advice

liver
When considering the use of Metgem 500 Tablet ER, it is important to be cautious if you have liver disease. This medication may not be safe for individuals with liver issues and it is advised to avoid using it in such cases. Please consult your doctor before taking Metgem 500 Tablet ER if you have liver disease.

kidney
Metgem 500 Tablet ER should be used carefully in individuals with kidney problems. Adjustment of the dose may be necessary. It is not advised for individuals with severe kidney disease. Please consult your doctor for guidance.

alcohol
It is unsafe to drink alcohol while taking Metgem 500 Tablet ER. Consult your doctor when consuming alcohol with Metgem 500 Tablet ER.

driving
When taking Metgem 500 Tablet ER, it's important to be aware of your blood sugar levels as they can impact your ability to drive. Avoid driving if you experience low or high blood sugar symptoms to ensure safety on the road.

pregnancy
Metgem 500 Tablet ER is generally safe to use during pregnancy. Animal studies show minimal negative effects on the baby, but human studies are limited.

breastfeeding
During breastfeeding, be cautious when using Metgem 500 Tablet ER. It is advised to pause breastfeeding until the mother's treatment is finished and the drug is no longer in her system.
Age above 75(Geriatrics)
Metgem 500 Tablet ER should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.
Age below 6 months(Pediatrics)
Metgem 500 Tablet ER should be used in children and adolescents (aged 10 years or older) only if prescribed by the physician. It is not recommended for use in children (aged below 10 years). However, consult your doctor before taking it.
Consumption warning before consuming Metgem 500 Tablet ER
Before consuming Metgem 500 Tablet ER, it is important to be aware of some warnings associated with its use. Some diabetic patients taking this medication may develop lactic acidosis, a serious condition where there is an excessive buildup of lactic acid in the blood. Proper liver and kidney function are necessary to eliminate this excess lactic acid. Individuals with kidney disease should not take metformin, the active ingredient in Metgem 500 Tablet ER, as indicated by a blood test. Furthermore, this medication may lead to lower levels of vitamin B-12, necessitating regular blood tests to monitor both blood sugar and vitamin levels. When Metgem 500 Tablet ER is used in combination with insulin, it can significantly reduce blood sugar levels, potentially requiring a dosage adjustment of insulin by the doctor.
Disease interactions
When it comes to Metgem 500 Tablet ER, individuals with conditions such as congestive heart failure and myocardial infarction, as well as those with Vitamin B12 deficiency or alcoholism, should steer clear of taking this medication. If you have any of these health issues, it's important to avoid using Metgem 500 Tablet ER to prevent any potential interactions that could be harmful to your health.
What if you forgot to take Metgem 500 Tablet ER?
If you forget to take your Metgem 500 Tablet ER, take it as soon as you remember. But if it's almost time for your next dose, just skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for the missed one.
What happens if you take overdose of Metgem 500 Tablet ER?
In the event that you or someone else unintentionally consumes an excessive amount of Metgem 500 Tablet ER, it is crucial to seek immediate medical assistance. Symptoms of an overdose may include vomiting, stomach pain accompanied by muscle cramps, a sense of overall unwellness characterized by severe tiredness, and difficulty breathing. It is imperative to consult a healthcare professional or go to the nearest hospital for prompt evaluation and appropriate intervention.
Related lab tests
Metgem 500 Tablet ER is often prescribed to help manage blood sugar levels in individuals with diabetes. To monitor the effectiveness of the treatment and ensure that the medication is working as intended, certain lab tests may be necessary. Related lab tests that are commonly recommended for individuals taking Metgem 500 Tablet ER include:
1. Glucose - Fasting Blood Test: This test measures the amount of sugar (glucose) in your blood after you have fasted for a certain period, usually overnight. It helps to determine your baseline blood sugar levels.
2. Glucose - Postprandial Blood Test: This test measures the amount of sugar (glucose) in your blood after you have eaten a meal. It helps to evaluate how well your body processes sugar after eating and how effectively the medication is controlling your blood sugar levels.
3. Glycosylated Hemoglobin (HbA1c) Test: This test measures the average blood sugar levels over the past two to three months by assessing the amount of glucose that has attached to hemoglobin in the red blood cells. It provides a broader picture of your blood sugar control and helps healthcare providers adjust your treatment plan if needed.
These lab tests are crucial in monitoring the effectiveness of Metgem 500 Tablet ER and ensuring that your blood sugar levels are within the target range. It is important to follow your healthcare provider's recommendations regarding the frequency of these tests to manage your diabetes effectively.
Additional Information
Habit Forming | No |
Chemical Class | Biguanide derivative |
Therapeutic Class | ANTI DIABETIC |
Action Class | Biguanides |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹22.51
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024