Meftal-MR Tablet is a medication that falls under the category of NSAID (Non-Steroidal Anti-Inflammatory Drug) medicines specifically designed to alleviate abdominal cramps experienced before and during the menstrual cycle. These cramps are characterized by pulsating pains in the lower abdomen due to the monthly menstrual cycle in females. For some individuals, the discomfort and pain accompanying menstruation can be severe, necessitating the use of medication to mitigate the intensity of the pain.

This tablet combines two key ingredients - 'mefenamic acid' and 'Tizanidine'. Mefenamic acid functions by inhibiting the activity of a chemical messenger in the body known as cyclo-oxygenase (COX) enzymes, which are responsible for producing prostaglandins (PG), chemicals that trigger pain. On the other hand, Tizanidine acts on the spinal cord and brain centers to relax the muscles of the stomach and intestine and curb muscle contractions. Together, these components work synergistically to alleviate pain, bloating, cramps, and discomfort associated with abdominal issues.

It is essential to take Meftal-MR Tablet as prescribed by your healthcare provider. The duration of the treatment would typically be determined by your doctor based on your medical condition. While using this medication, you may experience common side effects such as abdominal pain, nausea, vomiting, diarrhea, weakness, dry mouth, among others. Most of these side effects are mild and transient, typically resolving gradually over time. However, should these side effects persist, it is advised to seek guidance from your doctor.

Before initiating the use of Meftal-MR Tablet, it's crucial to inform your healthcare provider about any existing medical conditions or disorders you may have. Moreover, disclose all other medications you are currently taking to ensure the compatibility and safety of this medication for you. Pregnant or breastfeeding individuals should consult with their healthcare provider before commencing treatment with Meftal-MR Tablet to avoid any potential risks.

Meftal-MR Tablet contains a combination of Mefenamic Acid and Tizanidine and is primarily indicated for the treatment of painful menstrual periods and muscle spasms. It is contraindicated in patients with severe kidney, heart, or liver diseases, peptic ulcer, bleeding in the stomach, severe gastritis, inflammatory bowel disease, and certain hereditary enzyme deficiencies. Special caution is advised in patients with lung diseases, connective tissue disorders, epilepsy, dehydration issues, and those scheduled to undergo major surgical procedures. The usage of Meftal-MR Tablet is strictly not recommended for pregnant or breastfeeding women, children under 18 years, and elderly patients due to the heightened risk of adverse effects.

Common side effects associated with using Meftal-MR Tablet include drowsiness, dizziness, tiredness, reduced blood pressure, and dry mouth. In case these side effects worsen or do not improve, it is advisable to promptly consult with your healthcare provider for appropriate guidance.

Meftal-MR Tablet offers several benefits for individuals experiencing abdominal cramps. When taken at the onset of pain, this medication provides relief from pain and cramps by slowing down natural gut movements and relaxing stomach and intestinal muscles. It also works by reducing the activity of specific chemicals in the body that contribute to pain. The tablet contains a combination of 'mefenamic acid' and 'Tizanidine.' Mefenamic acid, categorized as an NSAID, effectively alleviates mild to moderate pain related to conditions such as period pain, premenstrual syndrome (PMS), and heavy periods by blocking the action of cyclo-oxygenase (COX) enzymes that produce prostaglandins, which are responsible for pain and swelling at injury sites. By reducing the production of prostaglandins, mefenamic acid helps in reducing pain and inflammation. Tizanidine, on the other hand, acts on the spinal cord and brain centers to relax stomach and intestinal muscles, preventing muscle contractions. Together, the components of Meftal-MR Tablet work synergistically to provide relief from pain, bloating, cramps, and discomfort associated with abdominal cramps, making it a valuable option for managing such symptoms effectively. However, it is essential to consult your doctor if the pain persists or worsens while taking this medication.

To use Meftal-MR Tablet, follow your doctor's instructions on the dose and duration for the best results. Swallow the tablet whole with a glass of water. It's important not to chew, crush, or break the tablet before taking it. Remember to take Meftal-MR Tablet with food as directed. Your physician will determine the right dose and duration based on factors like your age, body weight, and the specific condition being treated. Adhering to these guidelines will ensure you get the most benefit from this medication. If you have any questions or concerns about how to use Meftal-MR Tablet, don't hesitate to consult your doctor for further clarification.

Meftal-MR Tablet is commonly used to provide relief from abdominal cramps, especially those associated with the menstrual cycle. It is effective in treating painful periods and muscle spasms. By targeting the root cause of the discomfort, this medication helps alleviate the pain and discomfort caused by abdominal cramps. Additionally, Meftal-MR Tablet is known for its ability to provide quick and effective relief for those experiencing abdominal cramps.

Abdominal cramps are throbbing pains in the lower abdomen that many females experience monthly due to menstruation. Menstruation is the monthly shedding of the uterine lining when fertilization does not occur. Some females suffer severe pain and discomfort before and during menstruation, prompting the need for medication to alleviate the intensity of the pain. These cramps typically start one to two days before the period begins and may persist until its completion.

It is important to seek a doctor's advice before using MEFTAL MR TABLET if you have certain conditions such as peptic ulcer, bleeding in the stomach, severe gastritis, or inflammatory bowel disease. Do not take this tablet if you have rare hereditary problems of glucose-galactose malabsorption, galactose intolerance, or lapp lactase deficiency. Notify your doctor if you experience stomach or digestive problems, or if you have connective tissue disorders like systemic lupus erythematosus, epilepsy, bleeding disorder, or if you are scheduled for major surgery. Additionally, consult a doctor before using MEFTAL MR TABLET if you are dehydrated, had a stroke, or have high blood pressure, diabetes, high cholesterol, or if you are a smoker. This medication is not suitable for children and adolescents under 18 years old. Always seek guidance from a healthcare professional for appropriate usage.

Side effects may occur when taking Meftal-MR Tablet. These side effects are usually mild and may go away as your body gets used to the medication. Common side effects include nausea, vomiting, diarrhea, indigestion, loss of appetite, sleepiness, weakness, dryness in the mouth, heartburn, drowsiness, dizziness, tiredness, and reduced blood pressure and heart rate. Some individuals may also experience dry mouth, hallucinations, difficulty sleeping, upset stomach, and muscle weakness.

If you experience any of the following severe side effects, stop taking Meftal-MR Tablet and contact your doctor immediately: difficulty breathing or swallowing, swelling of the face, lips, tongue, or throat; severe itching of the skin with a red rash or raised lumps; blisters on the mouth, eyes, or genital region, along with patchy skin rash or peeling; diarrhoea with blood, black tarry stools, or vomiting blood; signs of internal bleeding like unusual bruising or nosebleeds; symptoms of anaemia such as tiredness, breathlessness, or paleness; fever, mouth ulcers, sore throat, or repeated infections; seizures; low sodium levels with headache, nausea, or muscle cramps; sudden headache, fever, sensitivity to light, stiff neck, drowsiness, and muscle pain; inflammation of the pancreas with abdominal pain, nausea, and vomiting; yellowing of the skin or eyes, pale stools, dark urine, or persistent nausea; sudden vision changes or eye pain; heart failure; or kidney function changes with fever, rash, nausea, and unusual changes in urine output.

It is important to monitor for these potential side effects and seek medical help if you experience any of them while taking Meftal-MR Tablet.

Before taking Meftal-MR Tablet, it is important to inform your doctor if you are allergic to this medication or other medicines. Meftal-MR Tablet can increase the risk of serious conditions such as fatal heart attack or stroke, gastrointestinal bleeding, ulceration, and perforation of the stomach and intestines. Avoid taking Meftal-MR Tablet if you are pregnant or breastfeeding unless instructed by your doctor. This medication may cause drowsiness and dizziness, so use caution when driving. Do not administer Meftal-MR Tablet to children as its safety and effectiveness in this age group have not been established.

Additionally, it is advisable to avoid consuming alcohol while on Meftal-MR Tablet as it can intensify drowsiness and dizziness, and may increase the risk of stomach bleeding. Do not combine Meftal-MR Tablet with other painkillers unless specifically directed by your doctor. Inform your healthcare provider about your health status and current medications to prevent any potential side effects. It is suggested not to exceed more than three doses of Meftal-MR Tablet in a day to prevent liver damage. If you have low blood pressure or liver or kidney diseases, consult your doctor before taking Meftal-MR Tablet. Also, be cautious of interactions with fluvoxamine and ciprofloxacin, as they may lead to adverse effects like slurred speech, dizziness, weakness, confusion, low blood pressure, or increased drowsiness.

When considering the disease drug interactions of Meftal-MR Tablet, it is important to note that individuals with certain health conditions need to exercise caution when using this medication. Patients with peptic ulcers, bleeding disorders, asthma, fluid retention, gastrointestinal toxicity, rash, renal toxicity, thrombosis, anaemia, heart failure, liver toxicity, high blood pressure, platelet aggregation inhibition, and hyperkalemia (high potassium levels) may experience interactions with Meftal-MR Tablet. It is advisable for individuals with these conditions to consult a healthcare professional before starting this medication to ensure it is safe and suitable for them.

If you forget to take a dose of Meftal-MR Tablet, try to take it as soon as you remember. But if it's nearly time for your next scheduled dose, it's best to skip the missed one and continue with your normal dosing routine. Avoid taking a double dose to make up for the missed one. It's important to keep track of your medicine schedule to ensure you receive the right amount of medication at the right times.

If you or someone else takes too much MEFTAL MR TABLET unintentionally, it is crucial to seek immediate medical assistance from a doctor or visit the nearest hospital. Overdosing on MEFTAL MR TABLET can lead to various symptoms such as seizures, severe headaches, stomach pain, feeling nauseous, vomiting, diarrhea, confusion, extreme excitement, loss of consciousness or coma, fatigue, ringing in the ears, fainting, dizziness, low blood pressure, pinpoint pupils, breathing difficulties, restlessness, and extreme drowsiness.

When taking Meftal-MR Tablet, it is important to monitor certain lab tests to ensure your liver and kidneys are functioning properly. The liver function test helps assess the health of your liver by measuring the levels of enzymes and proteins in the blood. This test is crucial to check for any signs of liver damage or disease, especially when taking medications that may impact liver function.

On the other hand, the kidney function test evaluates how well your kidneys are working by measuring the levels of waste products and other substances in the blood. Monitoring kidney function is essential as some medications, including Meftal-MR Tablet, can affect kidney function. Any abnormalities in kidney function can have serious implications on overall health.

Therefore, it is recommended to regularly undergo liver function tests and kidney function tests while using Meftal-MR Tablet to ensure the proper functioning of these vital organs. By monitoring these lab tests, healthcare providers can detect any potential issues early on and provide appropriate treatment if needed.

Related Lab Tests:
1. Liver function test
2. Kidney function test