Macox Plus Tablet

By Macox Plus

Rx

6 Tablet in a Strip

Composition icon

Composition

Rifampicin(450mg) + Isoniazid(300mg)

Manufacturer - Macleods Pharmaceuticals Pvt Ltd icon

Manufacturer - Macleods Pharmaceuticals Pvt Ltd

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Expires on or after icon

Expires on or after

June, 2026

About Macox Plus Tablet

Macox Plus Tablet is a combination medication prescribed for the treatment of tuberculosis, an infectious disease that primarily affects the lungs but can also spread to other parts of the body like the kidneys, brain, spine, and bone marrow. The tablet contains two anti-tuberculosis drugs, Rifampicin, and Isoniazid. Rifampicin works by inhibiting DNA-dependent RNA polymerase activity in the bacteria, while Isoniazid inhibits the biosynthesis of mycolic acid, a major component of the bacterial cell wall. Together, Macox Plus Tablet combats the bacteria Mycobacterium tuberculosis that causes tuberculosis.

It is crucial to follow your doctor's instructions when taking Macox Plus Tablet. The medication should be taken on an empty stomach at a fixed time to ensure its effectiveness. It is important not to exceed the recommended dosage to avoid harmful effects on your body. Even if you start feeling better, it's necessary to complete the full course of treatment. Abruptly stopping the medication may reduce its potency. If you miss a dose, take it as soon as you remember. The medicine may take some time to show its effects on the symptoms, so be patient. Consult your doctor if your condition worsens or does not improve.

Like any medication, Macox Plus Tablet may cause some common side effects such as nausea, vomiting, fever, dark-colored urine, sweating, and increased saliva. To alleviate these side effects, drink plenty of water. In case any side effects worsen, seek immediate medical attention. Serious side effects are rare, but if you experience any allergic reactions like rashes, itching, swelling, or difficulty breathing, seek immediate medical help.

Prior to taking Macox Plus Tablet, inform your doctor about any other medications you are taking for different health conditions. Patients with liver or kidney issues should use this medication cautiously under proper medical guidance. Pregnant or breastfeeding women should consult their doctors before taking Macox Plus Tablet. It is advisable to avoid alcohol consumption while on this medication to prevent excessive drowsiness and other potential complications. While the medication is generally not known to impair driving ability, refrain from driving if you feel drowsy or dizzy. Adequate rest and a healthy diet are recommended for a faster recovery. Your doctor may also advise certain laboratory tests during the treatment to monitor the effects of the medication on your body.


Benefits

Macox Plus Tablet, a powerful combination of medications, offers a range of benefits in the treatment of tuberculosis (TB). Tuberculosis is a serious infectious disease that primarily targets the lungs and can also impact other parts of the body. This medication effectively combats the infection-causing bacteria, both by eliminating them and by hindering their growth. By following the prescribed dosage and duration as instructed by your doctor, Eufacin Inh can significantly improve your symptoms, even though they may alleviate before the infection is fully eradicated. It is crucial not to discontinue the medication without consulting your doctor, as doing so could lead to a relapse or worsening of the infection. Adhering closely to your doctor's guidance is essential to ensure that you receive the maximum benefit from this treatment.


How to use the Macox Plus Tablet

To use Macox Plus Tablet, it is important to follow your doctor's instructions on dosage and duration. Swallow the tablet whole, without chewing, crushing, or breaking it. It is recommended to take Macox Plus Tablet on an empty stomach. Additionally, it is advised to avoid consuming tyramine-rich foods like cheese, smoked fish, meats, and certain types of beer while taking this medication. Adhering to these guidelines will help ensure the effectiveness of Macox Plus Tablet in managing your condition.


Uses of Macox Plus Tablet

Macox Plus Tablet is commonly used in the treatment of Tuberculosis (TB). This medication is specifically geared towards addressing TB, a bacterial infection that mainly affects the lungs. It is essential in managing the symptoms of TB and aiding in the eradication of the bacteria causing the infection. The tablet works by targeting and inhibiting the growth of the tuberculosis bacteria, thus helping to control and eliminate the infection. This makes Macox Plus Tablet a crucial component in the treatment regimen for individuals diagnosed with TB.


What conditions Macox Plus Tablet treats?

Macox Plus Tablet is used to treat tuberculosis, a contagious disease that primarily impacts the lungs but can also affect other body parts. It works by eliminating and preventing the growth of bacteria causing the infection. Follow the prescribed dosage and duration diligently. Even if you start feeling better, complete the full course of treatment to prevent the infection from recurring or worsening. Consult your doctor if the condition worsens or does not improve. Symptoms may improve before the infection is fully cleared, so do not stop the medication abruptly.


Should you consult a doctor?

If you experience any unusual or severe side effects such as nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, or allergic reactions like rashes, itching, swelling, or shortness of breath while taking Macox Plus Tablet for tuberculosis, it is important to seek medical help immediately.

Additionally, if you notice any worsening of your condition or if your symptoms do not improve while on the medication, consult your doctor promptly. Patients with liver or kidney issues should approach their healthcare provider before starting the treatment. Pregnant or nursing women should also seek medical advice before using this medicine.

Remember to take the prescribed dosage at the same time daily on an empty stomach, and complete the full course of treatment as directed, even if you start feeling better. Missing a dose should be compensated for as soon as you remember. If you experience persistent side effects, speak to your doctor for guidance on how to manage them.


Side effects of Macox Plus Tablet

When taking Macox Plus Tablet, you may experience side effects that typically improve as your body gets used to the medication. However, if they persist or cause concern, it's important to consult your doctor. Some common side effects include dark colored urine, rash, vomiting, jaundice, fever, increased liver enzymes, nausea, and peripheral neuropathy, which can cause tingling and numbness in the feet and hands.


Safety advice

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liver

When taking Macox Plus Tablet, it is essential to exercise caution if you have liver disease. Patients with liver issues may require a dose adjustment, so consulting your doctor before starting this medication is crucial. It is advised not to use Macox Plus Tablet in cases of severe liver disease. Your doctor can provide specific guidance tailored to your liver health status.

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kidney

Macox Plus Tablet requires caution in patients with kidney disease. Adjusting the dose may be necessary. Please consult your doctor before using Macox Plus Tablet.

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alcohol

When using Macox Plus Tablet, avoid alcohol to prevent symptoms like flushing, rapid heart rate, nausea, chest pain, and low blood pressure. This can cause a Disulfiram reaction.

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driving

Macox Plus Tablet may cause side effects like fits, mental health problems, and optic neuritis, which could impair your ability to drive. This may affect your driving ability, so caution is advised.

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pregnancy

Macox Plus Tablet may not be safe to use during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will assess the risks and benefits before prescribing. Please consult your doctor before using.

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breastfeeding

Macox Plus Tablet can be used safely during breastfeeding. Studies show that it has minimal transfer to breastmilk and is not harmful to the baby.


Consumption warning before consuming Macox Plus Tablet

Before taking Macox Plus Tablet, keep in mind that it is a prescription medicine used for treating tuberculosis. Take it exactly as prescribed by your doctor on an empty stomach at a fixed time each day for better results. Avoid exceeding the recommended dose to prevent harmful effects on your body. Completing the full course of treatment is crucial, even if you start feeling better. Abruptly stopping the medication might reduce its effectiveness.

Be aware that common side effects like nausea, vomiting, and fever may occur but can be managed by staying hydrated. Contact your doctor immediately if these side effects worsen or if you experience any allergic reactions. Inform your doctor about any other medications you are taking, especially if you have liver or kidney issues. Pregnant or nursing women should seek medical advice before using this medication.

Refrain from consuming alcohol while on this medication, as it can lead to excessive drowsiness. Although it generally does not impair driving abilities, avoid driving if it causes drowsiness or dizziness. Ensure to rest adequately and maintain a healthy diet during treatment. Your doctor may request lab tests to monitor your body's response to the medicine.


What if you forgot to take Macox Plus Tablet?

If you forget to take a dose of Macox Plus Tablet, take it as soon as you remember. But if it is almost time for your next dose, just skip the missed dose and continue with your normal schedule. It's important not to double up on doses to make up for the missed one. Stick to your prescribed dosage regimen to ensure the effectiveness of the medication.


Related lab tests

For monitoring the effects of Macox Plus Tablet, several related lab tests are recommended. These tests help in assessing the impact of the medication on different aspects of the body. The Complete Blood Count (CBC) test is crucial as it provides information about various blood components including red blood cells, white blood cells, and platelets. Another important test is the Erythrocyte Sedimentation Rate (ESR), which helps in evaluating inflammation in the body. Mycobacterium Tuberculosis DNA PCR - Qualitative test is essential for detecting the presence of tuberculosis DNA, especially if the patient is at risk of tuberculosis. Additionally, a Peripheral Smear Examination may be recommended to assess the appearance of blood cells under a microscope. These related lab tests can provide valuable insights into the patient's health status while on Macox Plus Tablet.


Additional Information

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 11-Feb-2025