Macbutin Tablet

By Macbutin

Rx

6 Tablet in a Strip

Composition icon

Composition

Rifabutin(150mg)

Manufacturer - Macleods Pharmaceuticals Pvt Ltd icon

Manufacturer - Macleods Pharmaceuticals Pvt Ltd

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Expires on or after icon

Expires on or after

July, 2026

About Macbutin Tablet

Macbutin Tablet is an antibiotic that is specifically used in the treatment of tuberculosis in individuals with HIV (human immunodeficiency virus) infection. When other antibiotics are ineffective due to weakened immunity, Macbutin Tablet aids in fighting against mycobacteria, a type of bacteria that are resistant to other treatments.

This medication may be taken either by itself or combined with other medicines to prevent serious infections caused by microorganisms such as mycobacterium avium complex (MAC). For optimal results, it is crucial to follow the dosage and duration as prescribed by your doctor. To maximize the benefits, it is recommended to take Macbutin Tablet on an empty stomach at the same time each day. It is imperative to strictly adhere to the prescribed duration of treatment to prevent the infection from recurring and becoming resistant.

Some individuals may experience temporary side effects while taking Macbutin Tablet, including decreased white blood cells, anemia, rash, nausea, and fever. These side effects typically dissipate as the body adjusts to the medication or during the course of treatment. If these side effects persist or become bothersome, it is advised to consult with your doctor.

Before initiating treatment with Macbutin Tablet, it is essential to inform your doctor if you are pregnant, breastfeeding, or have underlying liver, kidney, or heart conditions. Additionally, disclose any known allergies to medications. Regular monitoring through blood tests and chest x-rays may be required to ensure the effectiveness of the treatment and check for any active tuberculosis or other mycobacterial diseases. Your doctor may also recommend regular eye examinations and liver function tests while on this medication.


Benefits

Macbutin Tablet is a beneficial medication for individuals dealing with Tuberculosis with HIV infection. Specifically, it is effective in treating Mycobacterium avium complex disease (MAC), which is a bacterial infection that can result in severe symptoms. For patients with HIV, this tablet works by both killing and inhibiting the growth of the infection-causing bacteria, ultimately aiding in the treatment of the infection. It is crucial to follow the prescribed dosage and duration as recommended by your healthcare provider. While you may start to feel better before the infection is fully cured, it is important not to discontinue the medication without consulting your doctor. Failure to adhere to the prescribed regimen could lead to a return or exacerbation of the infection. By diligently following your doctor's guidance, you can maximize the benefits of Macbutin Tablet in managing your condition effectively.


How to use the Macbutin Tablet

To properly use Macbutin Tablet, follow the instructions provided by your doctor regarding the dose and duration of the medication. Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet. Remember to take Macbutin Tablet on an empty stomach as directed. It is important to avoid consuming acidic food and beverages such as sugar, certain dairy products, fish, processed foods, fresh meats, processed meats, sodas, and other sweetened beverages while taking this medication. By following these guidelines, you can ensure the effectiveness of Macbutin Tablet in managing your condition.


Uses of Macbutin Tablet

Macbutin Tablet is primarily used in the treatment of tuberculosis in individuals who are also infected with HIV. This medication is effective in managing the symptoms of tuberculosis in patients with HIV, providing relief and promoting recovery. By targeting the underlying bacterial infection, Macbutin Tablet helps in improving the overall health of individuals suffering from this dual condition. It is important to follow the prescribed dosage and regimen as advised by healthcare professionals for optimal results.


What conditions Macbutin Tablet treats?

Macbutin Tablet is used to treat Mycobacterium avium complex disease (MAC), a bacterial infection associated with tuberculosis in individuals with HIV infection. This medication fights the bacteria that other antibiotics cannot destroy, especially in people with weakened immune systems. It is crucial to follow the doctor's dosage instructions, take the tablet on an empty stomach, and maintain a consistent daily schedule. Continuing the treatment for the prescribed duration is essential to prevent the infection from recurring or becoming more difficult to treat. Some temporary side effects such as decreased white blood cells, anemia, rash, nausea, and fever may occur, but these typically improve as the body adapts to the medicine. Consulting the doctor if these side effects persist is advisable. Prior to initiating treatment, inform your doctor about any existing health conditions, allergies, or pregnancy or breastfeeding status to ensure safe usage of the medication. Regular monitoring through blood tests and x-rays may be recommended to monitor the progress of the treatment regimen.


Should you consult a doctor?

If you experience persistent nausea, rash, fever, anemia, or a decreased white blood cell count while taking Macbutin Tablet, it is recommended to seek advice from your doctor. These side effects are usually temporary and may disappear as your body gets used to the medicine. However, if they persist or if you are concerned about them, consulting with your healthcare provider is important. Additionally, before starting treatment with Macbutin Tablet, inform your doctor if you are pregnant, breastfeeding, or have any existing liver, kidney, or heart conditions. Regular monitoring through blood tests, chest x-rays, eye examinations, and liver function tests may be advised by your doctor to ensure the medication is safe and effective for you. It is essential to follow your doctor's instructions regarding the dose, duration of treatment, and taking the medication on an empty stomach for optimal results.


Side effects of Macbutin Tablet

When taking Macbutin Tablet, some common side effects may include nausea, rash, fever, anemia (low red blood cell count), and decreased white blood cell count. These side effects are typically mild and may go away as your body gets used to the medicine. However, if any of these side effects persist or if you are concerned about them, it is important to consult your doctor for further evaluation and guidance. It's always best to address any concerns with your healthcare provider to ensure your well-being.


Safety advice

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liver

When using Macbutin Tablet, it is important to exercise caution in patients with severe liver disease. It may be necessary to adjust the dose of the medication in such cases. Consult your doctor for guidance on the appropriate use of Macbutin Tablet to ensure your safety.

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kidney

Caution advised for individuals with severe kidney disease when taking Macbutin Tablet. Dose adjustment may be necessary. Always seek guidance from your doctor.

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alcohol

It is not known whether it is safe to consume alcohol with Macbutin Tablet. It is important to consult your doctor about alcohol intake while taking this medication.

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driving

When taking Macbutin Tablet, most people can usually drive safely.

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pregnancy

Macbutin Tablet is generally considered safe during pregnancy with low/no adverse effects on the developing baby based on animal studies. Limited human studies available.

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breastfeeding

Macbutin Tablet is considered safe for use during breastfeeding based on limited human data, indicating minimal risk to the baby.


Consumption warning before consuming Macbutin Tablet

Before consuming Macbutin Tablet, it is important to note that this antibiotic is specifically used for treating tuberculosis in individuals with HIV. Macbutin helps in fighting germs that are resistant to other antibiotics and can cause serious infections in people with weaker immune systems. This medication can be taken alone or in combination with other drugs to prevent infections by microorganisms like mycobacterium avium complex (MAC).

It is essential to follow the prescribed dose and duration as directed by your doctor. Macbutin should be taken on an empty stomach at the same time each day for the best results. Do not stop the medication early as it may lead to the infection reoccurring and becoming harder to treat.

While using Macbutin, some individuals may experience side effects such as decreased white blood cells, rash, nausea, and fever. These side effects are usually temporary and eventually disappear as your body adjusts to the drug. If you experience severe side effects or they persist, consult your doctor.

Before starting Macbutin Tablet, inform your doctor if you are pregnant, breastfeeding, or have any liver, kidney, or heart conditions or if you have any allergies. Regular monitoring through blood tests, x-rays, eye examinations, and liver function tests may be necessary during the treatment.


What if you forgot to take Macbutin Tablet?

If you forget to take a dose of Macbutin Tablet, take it as soon as you remember. But if it's close to the time for your next scheduled dose, just skip the missed one and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one.


Related lab tests

Related Lab Tests:
When taking Macbutin Tablet, there are certain lab tests that may be relevant to monitor your health and the effectiveness of the treatment. These tests can provide important information for both you and your healthcare provider.

1. HIV 1 - Quantitative (Viral Load): This test measures the amount of HIV virus in your blood. It helps in monitoring the progression of HIV infection and the effectiveness of antiretroviral therapy.

2. HIV 1 And 2 Antibody - ELISA: This test detects antibodies to both HIV-1 and HIV-2 in the blood. It is used to confirm HIV infection and is an important screening test for early detection.

3. Mycobacterium Tuberculosis DNA PCR - Qualitative: This test looks for the presence of Mycobacterium Tuberculosis DNA in samples such as sputum or fluid. It helps in the diagnosis of tuberculosis and monitoring the response to treatment.

These lab tests are crucial in ensuring appropriate management and monitoring of your health while taking Macbutin Tablet. Regular monitoring and follow-up with your healthcare provider based on these test results are essential for your overall well-being.


Additional Information

Habit FormingNo
Chemical ClassMacrolactams
Therapeutic Class-
Action ClassRNA polymerase inhibitors- Rifamycins

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Monie Riju Simon

MBBS - General Medicine

Last update on 11-Feb-2025