Luporal Capsule

By Luporal

Rx

10 Capsule in a Strip

Composition icon

Composition

Tegafur(100mg) + Uracil(224mg)

Manufacturer - Lupin Ltd icon

Manufacturer - Lupin Ltd

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Expires on or after icon

Expires on or after

April, 2027

About Luporal Capsule

Luporal Capsule is a prescription medicine used in the treatment of colon and rectal cancer. It contains a combination of two anticancer medicines that work together to prevent the growth and multiplication of cancer cells, ultimately aiding in the destruction of the tumor. It is essential to follow your doctor's prescribed dose and duration guidelines and take the medicine at a fixed time for maximum effectiveness.

The medicine is generally well tolerated by patients, but common side effects may include nausea, vomiting, hair loss, anemia, and a decrease in white blood cell count. Your doctor may recommend blood tests before or during treatment and may suggest supplements to address any deficiencies caused by the medication. Adding more fruits and vegetables to your diet can help overcome potential deficiencies.

It is important to inform your doctor if you are pregnant, breastfeeding, taking other medications, or suffering from any diseases before starting Luporal Capsule treatment. Driving or operating heavy machinery while on this medication is not advised. Additionally, the medication is not recommended for children, pregnant or breastfeeding women, or individuals with severe hepatic impairment, bone marrow suppression from previous radiotherapy, or dihydropyrimidine dehydrogenase deficiency disease.

Luporal Capsule, also known as Luporal Capsule 10's, contains Tegafur and Uracil, which are thymidylate synthase inhibitors. These components are used with calcium folinate to treat metastatic colorectal cancer, a type of cancer that starts in the colon or rectum and spreads to other parts of the body. Be sure to communicate any existing health conditions, especially related to heart, kidney, or liver function, before starting treatment.

Before taking Luporal Capsule, individuals aged 75 years or older, with age-related impaired kidney, liver, or heart function, should exercise caution, as well as those with other concomitant medications or diseases. The most common side effects associated with this medication include nausea, diarrhea, constipation, stomach pain, headache, dizziness, and dry skin. It is advisable to consult your doctor if any side effects worsen.


Benefits

Luporal Capsule is an effective treatment for cancer of the colon and rectum, providing several benefits to patients undergoing chemotherapy. This medication is specifically designed to lower the risk of developing further cancerous growths, aiding in the recovery process. With a recommended dosage of 28 days followed by a seven-day break, Luporal Capsule works to target and inhibit the growth and multiplication of cancer cells in the body. By strictly adhering to the treatment regimen as prescribed by your doctor, patients can experience a more comfortable recovery journey.

In addition to its anti-cancer properties, Luporal Capsule also offers the advantage of assisting in the first-line treatment of metastatic colorectal cancer when used in combination with calcium folinate. The active ingredients, Tegafur and Uracil, play a crucial role in interfering with the growth process of cancer cells, ultimately contributing to the management of the disease.

To maximize the benefits of Luporal Capsule, it is important to follow your healthcare provider's instructions diligently throughout the treatment period. Alongside the medication, patients are advised to avoid alcohol and smoking, as these substances can interfere with the efficacy of the drug. Staying hydrated by consuming an adequate amount of water is recommended to support the body during treatment.

Overall, Luporal Capsule presents a comprehensive approach to treating cancer of the colon and rectum, offering patients a chance to manage their condition effectively while enhancing their overall well-being.


How to use the Luporal Capsule

To use Luporal Capsule properly, it is important to follow your doctor's guidance on dosage and timing. You can take Luporal Capsule with or without food, but it is recommended to take it at the same time every day. It's best to take the capsule an hour before or after meals, as advised by your doctor.

Remember to swallow the capsule whole with water; do not crush or chew it. Follow your physician's instructions strictly and do not alter the way you take this medicine without consulting them first. Your doctor will determine the right dosage for you based on factors like your age and medical condition.

Always take Luporal Capsule exactly as directed to ensure its effectiveness and to avoid any potential side effects. If you have any questions or concerns about using this medication, consult your doctor for further clarification.


Uses of Luporal Capsule

Luporal Capsule is commonly used to treat colorectal cancer, specifically metastatic colorectal cancer. It is typically prescribed in combination with calcium folinate to effectively manage this type of cancer affecting the colon and rectum. By combining Luporal Capsule with calcium folinate, healthcare providers aim to target and treat metastatic colorectal cancer in patients.


What conditions Luporal Capsule treats?

Luporal Capsule is commonly used to treat colorectal cancer, which affects the colon or rectum by causing the growth of cells in the lower digestive tract. This type of cancer typically starts as non-cancerous polyps and can lead to symptoms such as abdominal discomfort, blood in the stool, and changes in bowel habits like constipation or diarrhea.


Should you consult a doctor?

If you experience signs of bone marrow suppression from past radiotherapy or have dihydropyrimidine dehydrogenase deficiency disease, avoid using Luporal Capsule. Seek medical advice if you show symptoms of bowel obstruction before taking this medication.


Side effects of Luporal Capsule

Luporal Capsule may cause temporary side effects as your body adjusts to the medication. Common side effects include nausea, vomiting, tiredness, mouth sores, sore tongue, stomach pain, diarrhea, and loss of appetite. Some people may also experience decreased blood cells, such as red cells, white cells, and platelets.

In some cases, more severe side effects may occur, including irregular heartbeat, heart attack, inflammation of the stomach lining, jaundice, urinary issues, impotence, chest pain, dehydration, weakness, eating disorders, confusion, altered taste, dizziness, headaches, numbness, shedding tears, breathlessness, coughing, constipation, indigestion, dry mouth, hair loss, skin issues, joint or muscle pain, and fever.

It is essential to consult your doctor if any side effects persist or if you are concerned about them. The side effects mentioned may not be experienced by everyone taking Luporal Capsule, but it is crucial to be aware of them as part of your treatment.


Safety advice

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liver

Caution should be exercised when considering the use of Luporal Capsule in individuals with liver disease. It is essential to seek guidance from a healthcare provider regarding the safety of using this medication if you have liver issues. Consulting with your doctor is crucial to ensure that Luporal Capsule is appropriate for your specific health condition related to your liver.

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kidney

Limited information is available on the use of Luporal Capsule in patients with kidney disease. Consult with your doctor for proper guidance before using Luporal Capsule.

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alcohol

Consult your doctor when consuming alcohol with Luporal Capsule.

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driving

When taking Luporal Capsule, be cautious when driving as it may cause tiredness, nausea, or blurred vision, impacting your ability to drive safely.

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pregnancy

Luporal Capsule is not safe to use during pregnancy. Studies on pregnant women and animals have demonstrated harmful effects on the developing baby. It is essential to consult a doctor before using this medicine during pregnancy.

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breastfeeding

It is better to consult your doctor before using Luporal Capsule.


Age above 75(Geriatrics)

Luporal Capsule should be used with caution in elderly patients (aged 75 years or above) with age-related impaired kidney, liver or heart function and other concomitant medications or diseases. Consult your doctor before taking Luporal Capsule.

Age below 6 months(Pediatrics)

Luporal Capsule is not recommended for use in children and adolescents (aged below 18 years). Consult your child’s doctor for advice.

Consumption warning before consuming Luporal Capsule

Before taking Luporal Capsule 10's, be aware that you should not consume this medication if you have allergies to any of its ingredients or if you are pregnant or breastfeeding. In case you become pregnant while using Luporal Capsule 10's, seek immediate medical advice. Remember, this medicine is not suitable for children, paediatrics, or adolescents. Watch out for signs of potential issues like fever, sudden feeling of illness, unexplained bleeding or bruising, anemia leading to tiredness and breathlessness, or conjunctivitis causing sore and inflamed eyes. Additionally, it is crucial to inform your doctor about any other medications, supplements, or herbal products you are taking alongside Luporal Capsule 10's for proper assessment and guidance.


Disease interactions

When considering disease drug interactions with Luporal Capsule, it is important to note that no interactions have been found or established based on available information. This means that Luporal Capsule does not have any known interactions with other drugs or diseases, providing reassurance for individuals who may be concerned about potential complications. This lack of interactions suggests that Luporal Capsule can be safely used without significant risk of negative effects due to interactions with other medications or underlying health conditions.


What if you forgot to take Luporal Capsule?

If you forget to take a dose of Luporal Capsule, try to take it as soon as you remember. But if it's close to the time for your next scheduled dose, it's best to skip the missed one. Don't take a double dose to make up for the one you missed. Keeping to your regular dosing schedule is important for the effectiveness of the medication.


What happens if you take overdose of Luporal Capsule?

In case of taking an excessive amount of Luporal Capsule, it is vital to seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, diarrhea, stomach ulcers, bleeding, and bone marrow suppression. If you or someone else experiences any of these symptoms, do not hesitate to contact a doctor or visit the nearest hospital for prompt assistance.


Related lab tests

In regard to Luporal Capsule, it is important to consider related lab tests such as Carcino Embryonic Antigen (CEA) testing. This test measures the level of CEA in the blood and is often used to monitor cancer progression or recurrence. Another relevant lab test is Biomarker testing of the tumor, which identifies specific genetic mutations or proteins in the tumor cells. Additionally, Colonoscopy is a diagnostic procedure that allows healthcare providers to examine the inside of the colon for any abnormalities. These related lab tests play a crucial role in the management and monitoring of conditions related to Luporal Capsule.


Additional Information

Habit FormingNo
Chemical Class-
Therapeutic ClassANTI NEOPLASTICS
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Mansi Chaudhari

MBBS - General Medicine

Last update on 11-Feb-2025