Lefno 5mg Tablet
By Lefno
Rx
10 Tablet in a Strip

Composition
Leflunomide(5mg)

Manufacturer - Ipca Laboratories Ltd
142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Expires on or after
February, 2027
About Lefno 5mg Tablet
Lefno 5mg Tablet is a medication used in the treatment of rheumatoid arthritis and psoriatic arthritis. These conditions can cause pain, swelling, and redness in the joints, making daily activities challenging. Lefno 5mg Tablet works by slowing down the progression of the diseases and providing relief from these symptoms, allowing for better mobility and comfort.
This tablet can be taken with or without food, but it is important to take it regularly at the same time each day to get the maximum benefit. Even if you start feeling better, it is essential to complete the prescribed dose as instructed by your doctor to ensure the best results in managing your condition.
While using Lefno 5mg Tablet, you may experience some common side effects such as nausea, headache, rash, and diarrhea. In some cases, there may be increased liver enzymes. If any of these side effects persist or worsen over time, it is recommended to consult with your doctor. They can provide guidance on managing or preventing these symptoms to make your treatment more comfortable.
Before starting this medication, it is crucial to inform your doctor about any existing heart, kidney, or liver problems you may have. Additionally, disclose all other medications you are currently taking to avoid any potential interactions. Your doctor may also suggest regular blood tests to monitor the medicine's effects on your liver and blood counts. Pregnant or breastfeeding mothers should seek medical advice before using Lefno 5mg Tablet to ensure the safety of both the mother and the baby.
Lefno 5mg Tablet belongs to a group of medicines known as anti-rheumatic agents. This medication contains Leflunomide, an immunomodulatory agent that works by blocking the production of DNA needed for the survival of immune system cells. By doing so, it suppresses the overactive immune response, reducing pain, inflammation, and swelling associated with these types of arthritis.
It is essential to follow your doctor's instructions regarding the dosage and timing of Lefno 5mg Tablet to optimize its effectiveness in managing rheumatoid arthritis and psoriatic arthritis. If you experience any persisting side effects or have concerns about the medication, do not hesitate to consult your healthcare provider for guidance and support.
Benefits
Lefno 5mg Tablet offers several benefits for individuals suffering from rheumatoid arthritis and psoriatic arthritis. In cases of rheumatoid arthritis, this medication effectively reduces the pain, stiffness, and swelling in the joints, thereby slowing down the progression of bone and joint damage. By providing relief from these symptoms, Lefno 5mg Tablet enables individuals to carry out their daily activities with greater ease, ultimately leading to an improvement in their quality of life. It is essential to take this medicine consistently at the same time each day to maximize its benefits. Even if the individual starts feeling better, continuing the prescribed dosage is crucial as it not only alleviates existing symptoms but also plays a preventive role in averting future harm.
For those dealing with psoriatic arthritis, Lefno 5mg Tablet proves to be beneficial in reducing the pain, stiffness, and swelling not only in the joints but also in the spine. Psoriatic arthritis, which is often linked with psoriasis, a skin condition characterized by rapid growth of skin cells leading to scales and dry patches, can cause significant discomfort through joint pain, stiffness, and swelling that may fluctuate over time. By addressing these symptoms, Lefno 5mg Tablet helps to enhance flexibility, thereby aiding in the prevention of disease progression. This ultimately empowers individuals to live a more fulfilling and active life despite the challenges posed by psoriatic arthritis.
Belonging to the group of anti-rheumatic agents, Lefno-10 Tablet 10's is a disease-modifying antirheumatic drug (DMARDs) that works by inhibiting an enzyme called dihydroorotate dehydrogenase and exhibiting antiproliferative activity, which suppresses cell growth. By taking this medication, individuals can experience relief from inflammation, redness, and swelling, thereby managing the symptoms of arthritis effectively. The comprehensive benefits of Lefno 5mg Tablet and its counterpart Lefno-10 Tablet 10's make them valuable treatment options for individuals seeking to alleviate the discomfort and challenges associated with rheumatoid arthritis and psoriatic arthritis, ultimately enhancing their overall quality of life.
How to use the Lefno 5mg Tablet
To use Lefno 5mg Tablet, it is important to follow your doctor's instructions on dosage and duration. Swallow the tablet whole with water, and do not chew, crush, or break it. You can take Lefno 5mg Tablet with or without food, but it is recommended to take it at the same time every day for better results. It is important to maintain consistency in taking this medication. If you are prescribed Lefno-10 Tablet 10's, the process is similar - swallow the tablet whole with water, do not crush or chew it, and you can take it with or without food. Following these instructions will help ensure the effectiveness of the medication in managing your condition. Remember to consult your doctor for any specific concerns or questions about using Lefno 5mg Tablet.
Uses of Lefno 5mg Tablet
Lefno 5mg Tablet is commonly used to treat conditions such as rheumatoid arthritis and psoriatic arthritis. In cases of rheumatoid arthritis, this tablet can help reduce the pain, swelling, and joint stiffness that often accompany this condition. Similarly, for individuals with psoriatic arthritis, Lefno 5mg Tablet can be effective in alleviating symptoms and improving joint function. By targeting the underlying inflammation, this medication can provide relief and enhance the quality of life for patients dealing with these types of arthritis.
What conditions Lefno 5mg Tablet treats?
'Lefno 5mg Tablet' is used to treat rheumatoid arthritis, an autoimmune disease causing joint pain, swelling, and inflammation, leading to difficulty in movement. Symptoms include intense knee joint pain and stiffness. Additionally, it helps manage psoriatic arthritis, characterized by skin inflammation and joint inflammation, affecting large joints in the lower extremities, toes, fingers, back, and pelvis. Symptoms include red, scaly skin patches, joint inflammation, and pain, impacting movement and causing swelling.
Should you consult a doctor?
If you experience persistent or worsening side effects such as nausea, headache, rash, diarrhea, increased liver enzymes, or dyspepsia while taking Lefno 5mg Tablet, it is important to consult your doctor. Additionally, if you have concerns about any side effects or experience dizziness, loss of appetite, hair loss, weight loss, or symptoms of bronchitis (inflammation of the airways), seeking medical advice is recommended.
Furthermore, it is crucial to inform your doctor before starting Lefno 5mg Tablet if you have existing heart, kidney, or liver issues. Your doctor may advise regular blood tests to monitor the impact of the medication on your liver and blood counts. Pregnant or breastfeeding individuals should consult their healthcare provider before using this medicine to ensure its safety for them and their baby.
Remember, even if you start feeling better, continue taking the medication as prescribed until the course is completed. This will help in achieving the maximum benefit from the treatment.
Side effects of Lefno 5mg Tablet
When taking Lefno 5mg Tablet, you may experience some side effects, which are important to be aware of. Most of these side effects are not severe and tend to diminish as your body gets used to the medication. However, if these effects persist or bother you, it is advisable to consult with your doctor. Some common side effects of Lefno 5mg Tablet include nausea, headache, rash, diarrhea, increased liver enzymes, dyspepsia (indigestion), dizziness, loss of appetite, hair loss, weight loss, and bronchitis (inflammation of the airways). Additionally, some people may also experience stomach pain and further indigestion. If you notice any of these side effects while taking Lefno 5mg Tablet, consult your healthcare provider for proper guidance.
Safety advice

liver
Lefno 5mg Tablet should be avoided by patients with liver disease as it is likely unsafe for them to use. It is important to consult your doctor before taking this medication to ensure your safety.

kidney
"Lefno 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed. Please consult your doctor."

alcohol
It is not safe to consume alcohol while taking Lefno 5mg Tablet. It is recommended to avoid alcohol when using this medication.

driving
Lefno 5mg Tablet can reduce alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these symptoms.

pregnancy
During pregnancy, it is not safe to use Lefno 5mg Tablet. Studies suggest harmful effects on the developing baby. Seek advice from your doctor.

breastfeeding
Lefno 5mg Tablet is believed to be unsafe during breastfeeding. Limited data shows it may pass into breastmilk and harm the baby.
Consumption warning before consuming Lefno 5mg Tablet
Before considering consuming Lefno 5mg Tablet, it is crucial to be aware of certain important warnings. Avoid taking this medication if you have a known allergy to leflunomide, severe liver or kidney issues, low blood protein levels, immune system disorders, bone marrow problems, or serious infections. It is not advisable for use in pregnant or breastfeeding women, as well as individuals under 18 years of age. Prior to starting Lefno 5mg Tablet, consult your healthcare provider if you have a history of serious infections such as interstitial lung disease, tuberculosis, or pneumonia. Be cautious while driving as this medication may cause dizziness. Additionally, Lefno 5mg Tablet can increase your vulnerability to infections, so promptly inform your doctor if you experience any signs of infection like a sore throat, difficulty breathing, jaundice, unusual bleeding, or bruising.
Disease interactions
When taking Lefno 5mg Tablet, it is important to inform your doctor about any existing health conditions you may have, such as low immunity, pneumonia, tuberculosis (TB), hypertension (high blood pressure), lung toxicity, peripheral neuropathy (nerve damage), and liver or kidney dysfunction. These conditions may interact with the medication and impact its effectiveness or your overall health. It is crucial to discuss these factors with your doctor to ensure the safe and proper use of Lefno 5mg Tablet.
What if you forgot to take Lefno 5mg Tablet?
If you forget to take your Lefno 5mg Tablet at the scheduled time, try to take it as soon as you remember. But if it's nearing the time for your next dose, it's better to skip the missed dose. Remember not to take a double dose to make up for the missed one. It's essential to stick to your regular dosing schedule to ensure the effectiveness of the medication.
Related lab tests
Related Lab Tests for monitoring the use of Lefno 5mg Tablet include tests for Rheumatoid Factor. These tests help in evaluating the presence of Rheumatoid Factor in the blood. The Rheumatoid Factor test is done through Agglutination and Turbidometry methods, which measure the level of Rheumatoid Factor in the blood. Additionally, the test for Rheumatoid Factor IgG Antibody can also be performed to detect specific antibodies related to Rheumatoid Factor. These lab tests are important in monitoring the progress of treatment with Lefno 5mg Tablet for conditions such as rheumatoid arthritis.
Additional Information
Habit Forming | No |
Chemical Class | Isoxazole Derivative |
Therapeutic Class | PAIN ANALGESICS |
Action Class | Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹98.16
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 11-Feb-2025