Jakavi 20mg Tablet

By Jakavi

Rx

14 Tablet in a Strip

Composition icon

Composition

Ruxolitinib(20mg)

Manufacturer - Novartis India Ltd icon

Manufacturer - Novartis India Ltd

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Expires on or after icon

Expires on or after

September, 2025

About Jakavi 20mg Tablet

Jakavi 20mg Tablet is a medication used to treat chronic idiopathic myelofibrosis and Polycythemia vera. It contains Ruxolitinib, which belongs to a group of medicines called kinase inhibitors. These conditions are related to bone marrow and blood cancers, including graft-versus-host disease (a complication of hematopoietic stem-cell transplant).

The tablet can be taken with or without food, preferably at the same time each day for maximum benefits. Your doctor will determine the appropriate dosage and frequency based on your condition, which may change over time. It is crucial to follow your doctor's instructions carefully to avoid serious side effects. While it may take some time to notice the benefits of Jakavi 20mg Tablet, do not stop taking it abruptly without consulting your doctor.

Common side effects of Jakavi 20mg Tablet include headache, dizziness, and low platelet count. This medication may decrease the number of blood cells, making you more susceptible to infections. Regular blood tests are necessary to monitor your blood cells, heart, liver, kidney, and lipid levels. Inform your doctor about any pre-existing liver or kidney issues, as well as any ongoing treatment for infections. Since Jakavi 20mg Tablet can interact with various medications, disclose all drugs you are taking to your healthcare provider.

It is important to note that Jakavi 20mg Tablet is not recommended during pregnancy or while breastfeeding. Both males and females undergoing treatment should use effective contraception to avoid pregnancy. If you experience any allergic reactions or persistent side effects while taking this medicine, consult your doctor promptly to address any concerns and ensure your well-being.


Benefits

Jakavi 20mg Tablet offers significant benefits for individuals suffering from Polycythemia vera and Chronic idiopathic myelofibrosis. In Polycythemia vera, a type of blood cancer characterized by the overproduction of red blood cells, Jakavi 20mg Tablet plays a crucial role. By halting the growth of cancer cells and preventing their multiplication, this medication effectively combats the disease. It also aids in reducing the risk of blood clot formation and associated serious health complications. Furthermore, Jakavi 20mg Tablet helps alleviate symptoms such as fever, bone pain, night sweats, and weight loss, thereby enhancing the quality of life for patients.


For individuals with Chronic idiopathic myelofibrosis, a condition where scar tissue forms in the bone marrow, Jakavi 20mg Tablet is equally beneficial. By effectively blocking the growth of cancer cells, this medication helps restore normal bone marrow function, addressing issues such as reduced red blood cell production and elevated white blood cell counts. Despite the possibility of experiencing some side effects, the advantages of Jakavi 20mg Tablet in managing Chronic idiopathic myelofibrosis are noteworthy.


Notably, Jakavi 20mg Tablet belongs to a group of medicines known as kinase inhibitors and contains Ruxolitinib as its active ingredient. By targeting specific enzymes called Janus Associated Kinases (JAK1 and JAK2), this medication provides targeted treatment, reducing spleen size, regulating red blood cell production, and mitigating symptoms associated with myelofibrosis and polycythemia vera. Additionally, Jakavi 20mg Tablet demonstrates effectiveness in managing graft-versus-host disease in both adults and children above 12 years old, showcasing its versatility and therapeutic value across various conditions. It is essential to have an open discussion with your doctor regarding the risks and benefits associated with Jakavi 20mg Tablet, while also adopting healthy lifestyle practices such as staying hydrated and avoiding alcohol and smoking during treatment.


How to use the Jakavi 20mg Tablet

To use Jakavi 20mg Tablet, follow the instructions given by your doctor. Take the prescribed dose as directed and do not exceed it. Swallow the tablet whole with water; do not break, chew, or crush it. You can take Jakavi 20mg Tablet with or without food, but it is recommended to take it at the same time each day for better results. Remember to take Jakavi 20mg Tablet exactly as your doctor has advised to ensure its effectiveness in managing your condition. If you have any questions or concerns about how to use this medication, consult your healthcare provider for guidance.


Uses of Jakavi 20mg Tablet

Jakavi 20mg Tablet is used in the treatment of conditions such as Polycythemia vera, Chronic idiopathic myelofibrosis, myelofibrosis, polycythaemia vera (PV), and graft-versus-host disease (GVHD). It is effective in managing these conditions by targeting specific signaling pathways involved in their progression.


What conditions Jakavi 20mg Tablet treats?

Jakavi 20mg Tablet is used to treat myelofibrosis, a condition where scar tissue replaces the bone marrow, leading to insufficient production of normal blood cells and enlargement of the spleen. Symptoms of myelofibrosis include abdominal fullness, bone pain, fatigue, easy bleeding/bruising, pale skin, and weight loss. Additionally, Jakavi 20mg Tablet is used for polycythaemia vera, a disorder where the bone marrow produces an excess of red blood cells, causing symptoms such as headache, confusion, dizziness, itching, night sweats, and extreme tiredness.


Should you consult a doctor?

If you experience persistent headaches, dizziness, or notice a decrease in blood platelets or red blood cells while taking Jakavi 20mg Tablet, it is important to seek medical attention. Additionally, if you have concerns about any side effects or if they persist, consulting your doctor is recommended.


Regular monitoring through blood tests is necessary to assess blood cell counts, heart, liver, kidney, and lipid levels. Inform your doctor about any existing liver or kidney issues, ongoing medication for infections, or any other medications you are taking to avoid harmful interactions. Effective contraception is crucial during treatment to prevent pregnancy.


Do not discontinue the medication without consulting your doctor, even if you do not immediately feel the benefits. Taking the prescribed dose at the same time every day as advised by your doctor is essential for optimal results. Be aware that improper usage or excess intake can lead to severe side effects.


Side effects of Jakavi 20mg Tablet

When taking Jakavi 20mg Tablet, you may experience certain side effects although not everyone will go through them. These side effects typically diminish as your body gets used to the medication. However, if they persist or cause you concern, it's important to consult your doctor promptly. Some common side effects include headaches, dizziness, and low blood platelets, which can lead to anemia due to a decrease in red blood cells. Additionally, you may also encounter issues like dizziness, headaches, weight gain, fever, cough, urinary tract infections, constipation, and hypertriglyceridemia, signifying high cholesterol levels. Be sure to discuss any side effects with your healthcare provider for proper guidance and management.


Safety advice

scroll

liver

When taking Jakavi 20mg Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment when using this medication. It is essential to consult your doctor before starting Jakavi 20mg Tablet, especially if you have hepatic impairment or a history of liver problems. Your doctor will be able to provide guidance tailored to your specific situation.

scroll

kidney

Use Jakavi 20mg Tablet with caution if you have kidney disease. Dose adjustment may be necessary. Avoid using if you have moderate to severe kidney disease. Inform your doctor if you have a history of kidney issues.

scroll

alcohol

It is not known if consuming alcohol with Jakavi 20mg Tablet causes harmful effects or interactions, as information is not available. Please consult your doctor for guidance.

scroll

driving

Jakavi 20mg Tablet may cause drowsiness, dizziness, or blurred vision. Avoid driving if you have these side effects. If you feel dizzy after taking Jakavi, refrain from driving or using heavy machinery.

scroll

pregnancy

Jakavi 20mg Tablet should not be used during pregnancy as it may harm the developing baby. Your doctor will evaluate the risks and benefits before prescribing. Do not take if pregnant. Consult your doctor if planning for pregnancy or if you suspect pregnancy.

scroll

breastfeeding

Jakavi 20mg Tablet is probably unsafe during breastfeeding. Limited data suggests it may pass into breastmilk, potentially harming the baby. It's not confirmed if Ruxolitinib passes into breastmilk. Avoid breastfeeding while using Jakavi 20mg Tablet and 2 weeks after the last dose.


Consumption warning before consuming Jakavi 20mg Tablet

Before taking Jakavi 20mg Tablet 14's, please note the following important warnings. Do not use this medication if you are allergic to any of its ingredients or if you are pregnant or breastfeeding. It is crucial to inform your doctor about any past or current medical conditions, such as infections, tuberculosis, hepatitis B, kidney or liver issues, skin cancer, HIV or AIDS, anemia, blood clotting problems, heart attack or stroke history, shingles, heart conditions, high cholesterol, low blood count, smoking habits, or undergoing dialysis treatment. Seek medical help immediately if you notice symptoms like unexpected bleeding or bruising, shortness of breath, frequent infections, extreme fatigue, pale skin, fever, chills, chronic cough with blood-tinged sputum, night sweats, weight loss, confusion, difficulty walking or speaking, weakness, blurred or loss of vision, painful skin rash with blisters, or any skin changes. Inform your doctor about all medications, supplements, or herbal products you are currently taking.


Disease interactions

When taking Jakavi 20mg Tablet, it is crucial to inform your doctor about any existing conditions you may have. These include heart problems, blood clots, hepatitis B infection, tuberculosis, infections, high lipid levels, lung issues, low blood count, or cancer. Being transparent about your medical history will help your doctor assess any potential interactions with Jakavi 20mg Tablet and make the necessary adjustments to ensure your safety and well-being.


Additional Information

Habit FormingNo
Chemical ClassPyrrolo[2,3-d]pyrimidines Derivative
Therapeutic Class-
Action ClassTyrosine kinase inhibitors

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

61367

Inclusive of all taxes

Content verified by

chevron-right

Dr. Upasana Bhatia

MBBS - General Medicine

Last update on 01-Oct-2024