Isorifazin S 100 mg/50 mg/300 mg Tablet
By Isorifazin S
Rx
10 Tablet in a Strip

Composition
Isoniazid(100mg) + Pyrazinamide(50mg) + Rifampicin(300mg)

Manufacturer - PCI Pharmaceuticals
3001 Red Lion Road, Philadelphia, PA, 19114, USA

Expires on or after
October, 2025
About Isorifazin S 100 mg/50 mg/300 mg Tablet
Isorifazin S 100 mg/50 mg/300 mg Tablet is a combination medicine prescribed for the treatment of tuberculosis. It is designed to inhibit the growth of the microorganisms responsible for the infection in the body. This medicine should only be used under the guidance and recommendation of a healthcare professional. It is important to adhere to the prescribed dosage and timing for optimal effectiveness. Taking it on an empty stomach and at a consistent time each day can enhance its efficacy. Overdosing on this medication can be harmful, so it is crucial to follow the prescribed amount strictly.
Completing the full course of treatment is essential, even if symptoms improve before completion. Abruptly stopping the medication can impact its effectiveness. While it may take some time for the medicine to exhibit its desired effects on symptoms, it is advisable to seek medical advice if there is worsening or no improvement in the condition.
Common side effects of Isorifazin S 100 mg/50 mg/300 mg Tablet include nausea, vomiting, fever, dark-colored urine, excessive sweating, and increased saliva production. Staying hydrated by drinking ample water can help manage these side effects. If any side effects worsen or become concerning, consulting a healthcare provider promptly is recommended. Severe side effects are uncommon, but immediate medical attention is necessary if signs of an allergic reaction such as rashes, itchiness, swelling, or difficulty breathing occur.
Before commencing treatment with this medication, inform your doctor about any other medicines you are currently taking for different health conditions. Individuals with liver or kidney issues should proceed with caution and consult a healthcare professional before using this medicine. Pregnant or breastfeeding women should also seek medical advice before starting treatment. Alcohol consumption should be avoided as it can intensify drowsiness when using this medicine. While it usually does not affect your ability to drive, refrain from driving if you experience drowsiness or dizziness. Adequate rest and a nutritious diet are essential for a swift recovery while undergoing treatment. Your doctor may request various laboratory and diagnostic tests during the course of treatment to assess the medication's impact on your body.
Benefits
Isorifazin S 100 mg/50 mg/300 mg Tablet is a medication used to treat tuberculosis, a serious infectious disease that primarily targets the lungs but can also affect other parts of the body. This tablet works by effectively killing and preventing the growth of the bacteria responsible for the infection, aiding in the treatment process. It is crucial to follow the prescribed dose and duration as directed by the doctor. While your symptoms may start to improve during the course of the treatment, it is essential to complete the full course as stopping prematurely can lead to the infection resurfacing or worsening. To ensure maximum benefit, it is advised to strictly adhere to your doctor's instructions throughout the treatment period.
How to use the Isorifazin S 100 mg/50 mg/300 mg Tablet
To use Isorifazin S 100 mg/50 mg/300 mg Tablet, follow the instructions given by your doctor regarding the dose and duration. Swallow the tablet whole with water, without chewing, crushing, or breaking it. Remember to take Isorifazin S 100 mg/50 mg/300 mg Tablet on an empty stomach for the best results. It is important to avoid consuming tyramine-rich foods like cheese, smoked fish, certain meats, and certain types of beer while taking this medicine to prevent any unwanted interactions. If you have any questions or concerns about how to use Isorifazin S 100 mg/50 mg/300 mg Tablet, don't hesitate to consult your healthcare provider for guidance.
Uses of Isorifazin S 100 mg/50 mg/300 mg Tablet
Isorifazin S 100 mg/50 mg/300 mg Tablet is primarily used in the treatment of tuberculosis (TB). TB is a serious infectious disease that mainly affects the lungs but can also affect other parts of the body. This tablet is specifically formulated for children and is part of a combination therapy regimen that helps to effectively combat TB bacteria. By using Isorifazin S 100 mg/50 mg/300 mg Tablet as prescribed by a healthcare provider, children can benefit from its anti-TB properties to improve their health and fight against this potentially life-threatening infection.
What conditions Isorifazin S 100 mg/50 mg/300 mg Tablet treats?
Isorifazin S 100 mg/50 mg/300 mg Tablet is used to treat tuberculosis, an infectious disease that affects the lungs and other parts of the body. It works by preventing the growth of the bacteria causing the infection. It is essential to take the medicine as prescribed by the doctor, on an empty stomach at a fixed time for better results. Completing the full course is crucial, even if you feel better, to ensure the infection is completely cured. Consult your doctor if there is no improvement or if you experience aggravation of symptoms.
Should you consult a doctor?
If you experience an aggravation of your condition or if your symptoms do not improve while taking Isorifazin S 100 mg/50 mg/300 mg Tablet, it is important to consult your doctor. Additionally, if you encounter common side effects such as nausea, vomiting, fever, dark-colored urine, or increased saliva that worsen, it is advisable to seek medical help promptly. Serious but rare side effects like allergic reactions (rashes, itching, swelling, shortness of breath) require immediate medical attention.
Patients with liver or kidney issues should use this medicine cautiously, after consulting with a healthcare provider. Pregnant or nursing women should also seek medical advice before taking the medication. It is recommended to avoid alcohol while on this treatment to prevent excessive drowsiness. If you feel excessively drowsy or dizzy, refrain from driving.
It is vital to complete the prescribed course of treatment even if you start feeling better, as prematurely stopping can impact the medicine's effectiveness. During the treatment, maintain a healthy diet and adequate rest for a speedy recovery. Your doctor may order laboratory tests to monitor the medication's impact on your body.
Side effects of Isorifazin S 100 mg/50 mg/300 mg Tablet
When taking Isorifazin S 100 mg/50 mg/300 mg Tablet, you may experience certain side effects. These side effects usually go away on their own as your body gets used to the medicine. However, if they persist or if you are concerned, it is essential to consult your doctor. Some common side effects of Isorifazin S 100 mg/50 mg/300 mg Tablet include nausea, vomiting, abdominal pain, skin rash, lethargy, and cutaneous reactions. Additionally, you may also experience peripheral neuropathy, which includes tingling and numbness in the feet and hands, as well as hepatitis, a viral infection of the liver. Other potential side effects include low blood platelets and thrombocytopenic purpura. If you notice any of these side effects while taking Isorifazin S 100 mg/50 mg/300 mg Tablet, it is important to seek advice from your healthcare provider.
Safety advice

liver
When using Isorifazin S 100 mg/50 mg/300 mg Tablet, it is important to be cautious if you have liver disease. It may be necessary to adjust the dosage of the tablet, so it's crucial to consult with your doctor before taking it. Regular monitoring of liver function tests is recommended both before and after starting the treatment to ensure the safe use of the medication.

kidney
Caution should be taken when using Isorifazin S 100 mg/50 mg/300 mg Tablet in patients with kidney disease. Dose adjustments may be necessary. Consult your doctor for guidance.

alcohol
When taking Isorifazin S 100 mg/50 mg/300 mg Tablet, avoid alcohol to prevent reactions like flushing, fast heart rate, nausea, thirst, chest pain, and low blood pressure.

driving
While taking Isorifazin S 100 mg/50 mg/300 mg Tablet, be cautious when driving. Side effects like dizziness, fainting, vision issues, or other reactions may impact your driving ability. Be aware of these symptoms before driving.

pregnancy
Isorifazin S 100 mg/50 mg/300 mg Tablet may not be safe during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will assess risks versus benefits before prescribing. Please consult your doctor.

breastfeeding
Isorifazin S 100 mg/50 mg/300 mg Tablet is likely safe for breastfeeding mothers based on limited human data showing no significant risks to the baby.
Consumption warning before consuming Isorifazin S 100 mg/50 mg/300 mg Tablet
Before consuming Isorifazin S 100 mg/50 mg/300 mg Tablet, please note that this is a prescription medicine used for treating tuberculosis by inhibiting the growth of infectious microorganisms. It should be taken on an empty stomach at a fixed time as directed by the doctor to maximize its effectiveness. Do not exceed the recommended dosage to avoid potential harmful effects on your health. If you miss a dose, take it promptly. Completing the full course of treatment is essential even if you start feeling better, as stopping abruptly can impact the medicine's potency.
Common side effects may include nausea, vomiting, fever, and dark-colored urine. Stay hydrated to manage these symptoms, and consult your doctor if they worsen. Serious side effects are rare, but seek immediate medical attention if you experience any allergic reactions like rashes, swelling, or shortness of breath.
Inform your doctor about any other medications you are taking and seek guidance if you have liver or kidney issues. Pregnant or breastfeeding women should consult with their healthcare provider before using this medicine. Avoid alcohol consumption, which may lead to increased drowsiness. While driving ability is generally unaffected, refrain from driving if you feel excessively drowsy or dizzy. Follow a healthy diet and get sufficient rest during treatment. Periodic laboratory tests may be recommended by your doctor to monitor your body's response to the medication.
What if you forgot to take Isorifazin S 100 mg/50 mg/300 mg Tablet?
If you forget to take a dose of Isorifazin S 100 mg/50 mg/300 mg Tablet, make sure to take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed one and continue with your regular dosing schedule. It’s important not to take a double dose to make up for the missed one.
Related lab tests
Related Lab Tests:
When taking Isorifazin S 100 mg/50 mg/300 mg Tablet, it is important to monitor certain lab tests to ensure the treatment is effective and safe. The following lab tests are commonly recommended to be done while taking this medication:
1. Complete Blood Count (CBC): This test measures various components of your blood, such as red blood cells, white blood cells, and platelets. It helps to monitor for any potential side effects of the medication on your blood cells.
2. Erythrocyte Sedimentation Rate (ESR): This test measures the rate at which red blood cells settle in a tube of blood. It is a non-specific indicator of inflammation in the body and can help track the progress of the treatment.
3. Mycobacterium Tuberculosis DNA PCR - Qualitative: This test detects the presence of Mycobacterium tuberculosis DNA in a sample. It is used to diagnose tuberculosis and can help in monitoring the response to treatment.
4. Peripheral Smear Examination: This test involves examining a sample of blood under a microscope to evaluate the different types of blood cells present. It can help in diagnosing certain blood disorders and monitoring the effects of the medication on blood cells.
These lab tests are important to track your health status and response to treatment while taking Isorifazin S 100 mg/50 mg/300 mg Tablet. It is recommended to follow your healthcare provider's guidance on when and how often to get these tests done.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | - |
Action Class | - |
FAQs
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Content verified by

Dr. Upasana Bhatia
MBBS - General Medicine
Last update on 11-Feb-2025