Humalog Mix 25 Kwikpen 100IU/ml
By Humalog Mix
Rx
3ml Suspension for Injection in a Disposable pen

Composition
Insulin Lispro(25%) + Insulin Lispro Protamine(75%)

Manufacturer - Eli Lilly and Company India Pvt Ltd
Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, HARYANA, INDIA

Expires on or after
July, 2026
About Humalog Mix 25 Kwikpen 100IU/ml
Humalog Mix 25 Kwikpen 100IU/ml is a medication used to help control blood sugar levels in individuals with type 1 and type 2 diabetes mellitus. This fast-acting insulin works quickly to lower blood sugar levels after meals, reducing the risk of serious diabetes-related complications. Typically, Humalog Mix 25 Kwikpen 100IU/ml is prescribed alongside other diabetes medications or a long-acting insulin. It is administered under the skin, either 15 minutes before or 20 minutes after starting a meal as instructed by your healthcare provider.
In addition to taking Humalog Mix 25 Kwikpen 100IU/ml, a comprehensive diabetes management program should include following a healthy diet, engaging in regular exercise, and maintaining a healthy weight under the guidance of your doctor. Monitoring blood sugar levels regularly is crucial for determining the appropriate dosage of the medication. The primary side effect of Humalog Mix 25 Kwikpen 100IU/ml is low blood sugar (hypoglycemia), which can be prevented by properly administering the medication, having regular meals, and monitoring blood sugar levels consistently. It is important to avoid excessive alcohol consumption as it can further lower blood sugar levels. Injection site reactions such as redness, swelling, or lumps can occur, along with itching and rash in some cases.
Before starting treatment with Humalog Mix 25 Kwikpen 100IU/ml, it is important to inform your healthcare provider of any history of kidney, liver, or heart issues. Pregnant or breastfeeding individuals should also seek medical advice as dosage adjustments may be necessary. Humalog Mix 25 Kwikpen 100IU/ml contains insulin lispro and insulin lispro protamine, which work together to regulate blood sugar levels effectively by controlling sugar production in the liver and enhancing sugar absorption in fat and muscle cells. This medication is suitable for use in individuals under 18 years old, with precautions to be taken when driving and avoiding alcohol consumption.
Additionally, Humalog Mix 25 Kwikpen 100IU/ml should be stored in the refrigerator between 2-8°C to maintain its effectiveness, and should not be frozen. Those using this medication should be aware of side effects such as hypoglycemia, itching, rash, and injection site reactions, which typically do not require medical intervention and often resolve with time. However, persistent side effects should be reported to a healthcare provider for further evaluation and management. Consulting a doctor before starting or adjusting treatment with Humalog Mix 25 Kwikpen 100IU/ml is essential to ensure safe and effective diabetes management.
Benefits
Humalog Mix 25 Kwikpen 100IU/ml, a medication used in the treatment of diabetes, offers several benefits for individuals managing their blood sugar levels. This medication combines Insulin Lispro Protamine and Insulin Lispro to provide both a prolonged duration of action and a fast onset of action. By working together, they ensure rapid and consistent sugar control, helping to regulate blood sugar levels effectively for an entire day. Proper use of Humalog Mix 25 Kwikpen 100IU/ml under the guidance of a healthcare professional can significantly reduce the risk of serious diabetes-related complications such as kidney damage, eye damage, nerve problems, and the potential loss of limbs.
As an antidiabetic medication, Humalog Mix 25 Kwikpen 100IU/ml is designed to improve blood sugar control in adults with diabetes mellitus. Its combination of fast-acting insulin lispro and intermediate-acting insulin lispro protamine helps lower glucose levels in the blood by regulating the production of sugar in the liver and facilitating its reuptake in fat and muscle cells. This mechanism of action ensures rapid and consistent sugar control throughout the day, aiding in the prevention of complications associated with diabetes, such as retinopathy, nephropathy, neuropathy, diabetic foot ulcers, and other diabetes-related complications.
Humalog Mix 25 Kwikpen 100IU/ml starts to work within 10 minutes of injection, reaches its peak effectiveness in 2 hours, and continues working for up to 24 hours. This sustained action helps maintain stable blood glucose levels over an extended period, supporting individuals in managing their diabetes effectively with improved quality of life. When used regularly in conjunction with a proper diet and exercise plan, Humalog Mix 25 Kwikpen 100IU/ml can contribute to living a normal and healthy life by promoting better blood sugar control and reducing the risk of diabetes-related complications.
How to use the Humalog Mix 25 Kwikpen 100IU/ml
To use Humalog Mix 25 Kwikpen 100IU/ml safely and effectively, it is essential to follow the guidance of your doctor or nurse. This medicine should not be self-administered; always seek professional help for administration. The injection should be given subcutaneously, meaning into the upper thigh, abdomen, upper arm, or buttocks. It should never be injected intravenously or into a vein. If you are not confident about self-administering, do ask your healthcare provider for assistance.
When administering Humalog Mix 25 Kwikpen 100IU/ml, consult a healthcare professional for supervision. The injection should be given in the thighs, buttocks, upper arm, or abdomen, subcutaneously. It should always be 10 minutes before a meal. After the injection, consume a meal or snack with carbohydrates within 20 minutes to prevent low blood sugar.
Before use, roll the vial or cartridge in your hands until the liquid is evenly cloudy. While injecting, ensure the needle remains under the skin for at least 6 seconds to ensure the full dose is administered. Check the cartridge or vial for any observable particulates or discoloration before use, and discard the needle and syringe after each use to avoid infections.
To prevent skin damage, avoid injecting repeatedly in the same spot; instead, rotate the injection site. Get advice from your doctor before changing the site. Do not mix Humalog Mix 25 Kwikpen 100IU/ml with any other insulins. Consult your doctor before adjusting the dosage or frequency based on your age, weight, and health condition. Do not discontinue using this medication without consulting your healthcare provider.
Uses of Humalog Mix 25 Kwikpen 100IU/ml
Humalog Mix 25 Kwikpen 100IU/ml is primarily used to improve glycemic control in patients with diabetes mellitus, encompassing both type 1 and type 2 diabetes. It aids in managing blood sugar levels effectively. This medication can be particularly beneficial for individuals requiring insulin therapy to regulate their glucose levels. The Humalog Mix 25 Kwikpen 100IU/ml is designed to assist patients in achieving better control over their diabetes through the convenient and precise delivery of insulin.
What conditions Humalog Mix 25 Kwikpen 100IU/ml treats?
In Type 1 diabetes, the body doesn't produce insulin, essential for regulating blood sugar levels. In Type 2 diabetes, the body either doesn't make enough insulin or cannot effectively use the insulin produced. Insulin is crucial for controlling blood sugar levels in the body.
Should you consult a doctor?
You should seek advice from your doctor before using Humalog Mix 25 Kwikpen 100IU/ml if you have certain conditions or situations. Talk to your doctor if you have issues with your adrenal, pituitary, or thyroid glands. It's also essential to consult your doctor if you’ve recently made changes to your diet and lifestyle, increased your exercise routine, or experienced illness or infections. If you are planning to travel abroad, it's best to get medical advice as your mealtime and injection schedules may need adjustments. Seek medical guidance if you have a history of strokes. Avoid using Humalog Mix 25 Kwikpen 100IU/ml if you are prone to hypoglycemia.
Side effects of Humalog Mix 25 Kwikpen 100IU/ml
Side effects of Humalog Mix 25 Kwikpen 100IU/ml may occur as your body gets used to the medication. These side effects are usually minor and may go away on their own over time. You may experience weight gain, swelling at the injection site, low blood sugar levels (hypoglycemia), edema (swelling), and skin rash. Additionally, you might notice itching, rash, diabetic retinopathy (eye diseases related to diabetes), swelling around the ankles and joints, and lumps under the skin.
It’s important to be aware of potential side effects like lipodystrophy (shrinkage of fat tissues), pain at the injection site, and painful neuropathy resulting from nerve damage. If you encounter severe side effects, seek immediate medical attention. These include allergic reactions like generalized skin rash with itching, sweating, and swelling, as well as difficulty breathing and loss of consciousness. Signs of severe low blood sugar levels such as cold sweats, rapid heartbeat, and confusion should also prompt contacting your doctor promptly. Moreover, symptoms of heart failure, such as shortness of breath and chest pain, and high blood sugar levels indicated by nausea, vomiting, and fruity breath, require immediate medical evaluation.
Consult your healthcare provider if any side effects persist or if you have concerns about them. It’s crucial to address any unusual reactions promptly to ensure your well-being while using Humalog Mix 25 Kwikpen 100IU/ml.
Safety advice

liver
When using Humalog Mix 25 Kwikpen 100IU/ml, it is important to exercise caution in patients with liver disease. It may be necessary to adjust the dosage of this medication in such individuals. To ensure proper management, it is advised to consult your doctor before using Humalog Mix 25 Kwikpen 100IU/ml. Regular monitoring of glucose levels is also recommended to facilitate any necessary dose adjustments.

kidney
Humalog Mix 25 Kwikpen 100IU/ml requires caution in individuals with kidney disease. Dose adjustment may be necessary, and medical consultation is advised. Regular blood glucose monitoring is recommended for proper dosage.

alcohol
It is not safe to drink alcohol while using Humalog Mix 25 Kwikpen 100IU/ml.

driving
When using Humalog Mix 25 Kwikpen 100IU/ml, avoid driving if you experience low or high blood sugar symptoms that could affect your focus and reaction time. Your ability to drive may be impacted in such cases.

pregnancy
Humalog Mix 25 Kwikpen 100IU/ml is generally safe during pregnancy. Animal studies show minimal harm to the baby, but human studies are limited.

breastfeeding
During breastfeeding, caution is advised when using Humalog Mix 25 Kwikpen 100IU/ml. It is recommended to pause breastfeeding until the mother's treatment is finished and the drug is no longer in her system.
Age above 75(Geriatrics)
Humalog Mix 25 Kwikpen 100IU/ml should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before administration. Proper dose adjustments and careful monitoring of blood glucose levels and kidney functions are required in such patients
Age below 6 months(Pediatrics)
Consult your doctor before injecting Humalog Mix 25 Kwikpen 100IU/ml in children and adolescents (aged below 18 years).
Consumption warning before consuming Humalog Mix 25 Kwikpen 100IU/ml
Before using Humalog Mix 25 Kwikpen 100IU/ml, it is important to consider certain warnings for your safety. Firstly, if you are allergic to any components of this medication, kindly notify your doctor. This medication is not suitable for individuals under 18 years old. Prior to using Humalog Mix 25 Kwikpen 100IU/ml, disclose any history of liver or kidney disease, or low blood potassium levels to your healthcare provider. If you are pregnant or breastfeeding, consult your doctor before using this medication. Be cautious when driving, as Humalog Mix 25 Kwikpen 100IU/ml can induce low blood sugar levels (hypoglycemia). It is advised to abstain from consuming alcohol while using this medication. Remember that Humalog Mix 25 Kwikpen 100IU/ml should be stored in a refrigerator at temperatures between 2-8°C to maintain its effectiveness; do not freeze it. Additionally, keep your doctor updated on your health status and other medications to prevent any potential side effects.
Disease interactions
When considering taking Humalog Mix 25 Kwikpen 100IU/ml, it is crucial to inform your doctor about any history of kidney disease, liver conditions like hepatic impairment or liver disease, hypoglycemia (low blood sugar), and hypokalaemia (low potassium level). These conditions can potentially interact with the medication, affecting its effectiveness or causing adverse reactions. Your doctor will need this information to make informed decisions about the safety and appropriate dosage of Humalog Mix 25 Kwikpen 100IU/ml for you. It is always best to be transparent about your medical history to ensure that you are safely and effectively managing your diabetes with Humalog Mix 25 Kwikpen 100IU/ml.
What if you forgot to take Humalog Mix 25 Kwikpen 100IU/ml?
If you forget to take a dose of Humalog Mix 25 Kwikpen 100IU/ml, it could lead to high blood sugar levels known as hyperglycemia. To manage this situation, start by checking your blood sugar level to determine the current status. Based on the reading, adjust your next dose accordingly. It is important to stay in control of your blood sugar levels to ensure the effectiveness of your treatment. Remember to keep track of your doses and consult your healthcare provider if you have any concerns or questions about missed doses.
What happens if you take overdose of Humalog Mix 25 Kwikpen 100IU/ml?
If someone takes too much Humalog Mix 25 Kwikpen 100IU/ml, it can lead to a serious condition called hypoglycemia. If this happens, it's important to contact a doctor right away or go to the hospital. Symptoms of hypoglycemia may include fainting, feeling unwell, sweating, vomiting, difficulty breathing, a rapid heartbeat, and dizziness.
Related lab tests
Related Lab Tests for monitoring the use of Humalog Mix 25 Kwikpen 100IU/ml may include the following tests:
1. HbA1C (Glycated Hemoglobin): This test measures the average blood sugar levels over the past 2-3 months, providing an overall view of blood sugar control.
2. Blood Glucose Fasting (FBS): This test measures blood sugar levels after fasting for at least 8 hours, giving an indication of how the body processes sugar.
3. Insulin-Fasting: This test measures the insulin levels in the blood while fasting, helping to evaluate insulin resistance or deficiency.
4. Diabetic Checkup: This comprehensive checkup may include tests such as lipid profile, kidney function tests, and liver function tests to assess overall health in diabetic individuals.
5. Advance Diabetes Monitoring (Senior Female): This specialized monitoring may include additional tests such as renal function tests, eye exams, and nerve function tests to screen for complications related to diabetes in senior females.
Additional Information
Habit Forming | No |
Chemical Class | - |
Therapeutic Class | ANTI DIABETIC |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024