Grandem Injection

By Grandem

Rx

3ml Injection in a Vial

Composition icon

Composition

Granisetron(1mg)

Manufacturer - Aristo Pharmaceuticals Pvt Ltd icon

Manufacturer - Aristo Pharmaceuticals Pvt Ltd

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.

Expires on or after icon

Expires on or after

August, 2025

About Grandem Injection

Grandem Injection is a medication that falls into the category of anti-emetic drugs, primarily utilized to manage nausea and vomiting brought on by surgical procedures or cancer treatments like chemotherapy or radiation therapy. Nausea is an uncomfortable sensation in the stomach that often precedes vomiting, which is the act of forcibly emptying the stomach's contents through the mouth. The active ingredient in Grandem Injection is Granisetron, which is classified as a 5-HT3 receptor antagonist, also known as a serotonin receptor antagonist or serotonin blocker. By blocking the activity of serotonin, a chemical messenger in the brain that triggers feelings of nausea and vomiting during cancer treatments or after surgery, Granisetron helps alleviate these symptoms.

It is essential to note that Grandem Injection should only be administered by a healthcare professional and not self-administered. The dosage and duration of treatment will be determined by the doctor based on the severity of the individual's condition. Some common side effects associated with Grandem Injection include diarrhea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, and pain, redness, or swelling at the injection site. These side effects vary in intensity from person to person, and if any become unmanageable, it is crucial to consult with a doctor for guidance.

Before starting treatment with Grandem Injection, individuals should inform their healthcare provider about any other prescription or non-prescription medications they are taking. Additionally, individuals with pre-existing liver, kidney, or heart conditions, stomach or intestinal problems, allergies, or low levels of potassium and magnesium in the blood should disclose this information to their doctor before using Grandem Injection. It is advised to avoid driving or operating machinery if Grandem Injection causes dizziness or drowsiness, and individuals who are pregnant, planning for pregnancy, or breastfeeding should consult with their healthcare provider before using this medication. Consumption of alcohol while undergoing treatment with Grandem Injection should be avoided as it may lead to unwanted side effects.


Benefits

Grandem Injection offers significant benefits for individuals experiencing nausea and vomiting as a result of chemotherapy treatment. By blocking the effects of certain chemicals in the body that cause feelings of sickness, Grandem Injection effectively helps to alleviate these distressing symptoms. Specifically designed to address the challenges of nausea and vomiting commonly associated with cancer treatments like chemotherapy and radiation therapy, this medication plays a crucial role in enhancing the overall comfort and well-being of patients undergoing such therapies. Administered as an injection under the supervision of a healthcare provider, Grandem Injection ensures that the dosage is tailored to meet the individual's specific treatment needs. It is vital to follow the guidance of a medical professional and avoid self-administration of this medication to prevent any potentially harmful side effects. With its targeted approach and proven efficacy in managing chemotherapy-induced nausea and vomiting, Grandem Injection emerges as a valuable and supportive resource for individuals navigating the rigors of cancer treatment.


How to use the Grandem Injection

When using Grandem Injection, it is important to always have a doctor or nurse administer the medicine to you. Do not try to give yourself the injection. Follow the instructions provided by your healthcare provider carefully to ensure the medicine is administered correctly. It is important to be compliant with the dosage and frequency prescribed by your doctor. Make sure to inform your healthcare provider about any other medications you are taking to avoid potential drug interactions. If you have any questions or concerns about using Grandem Injection, do not hesitate to discuss them with your healthcare provider for proper guidance and support.


Uses of Grandem Injection

Grandem Injection is commonly used to relieve nausea and vomiting caused by chemotherapy. This medication is effective in helping patients undergoing cancer treatment manage these distressing side effects. By administering Grandem Injection, healthcare professionals can provide relief and improve the overall well-being of individuals experiencing chemotherapy-related nausea and vomiting.


What conditions Grandem Injection treats?

Grandem Injection is prescribed to control nausea and vomiting triggered by surgery, cancer drug therapy, or radiotherapy. It does not address other cancer treatment side effects. The common side effects may include injection site pain, headache, constipation, diarrhea, and weakness. It is crucial to follow healthcare provider instructions and complete the recommended treatment course. Inform your doctor about any existing heart, liver, or gastrointestinal issues, as well as other medications you are taking, to prevent potential interactions. Pregnant or breastfeeding individuals should consult their healthcare team before using this medication.


Should you consult a doctor?

Seek medical attention if you experience persistent injection site pain, constipation, diarrhea, headache, weakness, or insomnia while taking Grandem Injection. These common side effects should improve when you stop the medication, but if they continue or become bothersome, consult your doctor for advice on managing them. Additionally, inform your doctor if you have heart or liver conditions, intestinal blockages, or if you are using other medications for various health issues. It is crucial to follow your healthcare provider's guidance on the duration of Grandem Injection treatment and the transition to tablets once deemed appropriate. If you are pregnant or breastfeeding, seek advice from your healthcare team before using this medication. Your doctor can address any concerns or recommend strategies to alleviate side effects.


Side effects of Grandem Injection

Grandem Injection may cause side effects, which usually do not need medical attention and may go away as your body gets used to the medicine. If side effects persist or cause concern, it is advisable to consult your doctor. Common side effects of Grandem Injection include pain at the injection site, constipation, diarrhea, headache, weakness, and difficulty sleeping (insomnia). Be aware of these possible side effects and seek medical advice if needed.


Safety advice

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liver

When it comes to liver issues, it seems that Grandem Injection can generally be considered safe for use in patients with liver disease. The available data indicates that adjusting the dose of Grandem Injection may not be necessary for these patients. However, it is always best to seek advice from your doctor before using Grandem Injection to ensure it is safe and appropriate for your specific situation.

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kidney

Grandem Injection is likely safe for use in individuals with kidney disease. Existing data indicates that dosage adjustment may not be required for these patients. It is recommended to seek advice from your healthcare provider.

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alcohol

It is not known if it is safe to drink alcohol while using Grandem Injection. Kindly consult your doctor for advice.

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driving

When using Grandem Injection, your driving ability is typically not affected.

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pregnancy

Grandem Injection is believed to be safe for use during pregnancy based on animal studies showing minimal adverse effects on the baby. Limited human studies are available.

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breastfeeding

Grandem Injection is considered safe during breastfeeding based on limited human data indicating no significant risk to the baby. It is advisable to consult your doctor for personalized guidance.


Consumption warning before consuming Grandem Injection

Before using Grandem Injection for managing nausea and vomiting, it is crucial to understand certain key points. This medication is primarily aimed at alleviating these specific symptoms related to surgery, cancer drug therapy, or radiotherapy. Remember, Grandem Injection does not address other side effects linked to cancer treatments. It is essential to only take this medication as directed by your healthcare provider and continue the injections until your doctor indicates it is safe to discontinue them. Following this, your doctor may transition you to tablets instead of injections. Be mindful of potential side effects such as injection site pain, headache, constipation, diarrhea, and weakness. While these side effects may diminish upon discontinuation, consult your doctor if they persist. Inform your doctor about any heart or liver issues, gastrointestinal blockages, and all other medications you are using, especially those for epilepsy, heart conditions, cancer, or depression as there could be interactions with Integron. If you are pregnant or nursing, seek advice from your healthcare team before starting this medication.


What if you forgot to take Grandem Injection?

If you forget to take a dose of Grandem Injection, try to take it as soon as you remember. But if it's close to the time for your next scheduled dose, then it's best to just skip the missed dose. It's important not to take a double dose to make up for the missed one. Just continue with your regular dosing schedule to maintain the effectiveness of the medication.


Additional Information

Habit FormingNo
Chemical ClassIndazole Derivative
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin antagonists (5-HT3 antagonists)

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 01-Oct-2024