Grafnos 1 Capsule

By Grafnos

Rx

10 Capsule in a Strip

Composition icon

Composition

Tacrolimus(1mg)

Manufacturer - Akognos Life Sciences icon

Manufacturer - Akognos Life Sciences

Corporate & Registered Office, Akognos Life Sciences Pvt. Ltd., Manish Plaza, Third Floor, Plot No. 25, Sector-20 , Dwarka, New Delhi -110075

Expires on or after icon

Expires on or after

August, 2025

About Grafnos 1 Capsule

Grafnos 1 Capsule is a medication used in combination with other drugs to prevent the body from rejecting a newly transplanted organ like the liver, kidney, or heart. This drug falls under the category of immunosuppressants, which work by weakening the immune system to prevent it from attacking the new organ. The dosage of Grafnos 1 Capsule varies based on the type of transplant, body weight, and other medications being taken. It is essential to follow the doctor's instructions diligently, taking the capsule on an empty stomach to maximize its benefits.

However, Grafnos 1 Capsule comes with potential side effects that require medical attention. Some common side effects include the aggravation of diabetes and kidney issues, along with tremors, infections, high blood pressure, and insomnia. It is crucial to inform your doctor if you have existing kidney, liver, or heart problems, diabetes, high blood pressure, or if you are taking medications for infections, pain, or arthritis. Limiting sun exposure is also recommended as immunosuppressants may increase the risk of skin cancer.

For both men and women using Grafnos 1 Capsule, effective birth control is necessary to prevent pregnancy. Pregnant or breastfeeding individuals should consult their doctor before using this medication, as it is not generally recommended during these periods unless medically necessary. Regular medical tests and blood pressure checks are essential before and during treatment to monitor progress.

Grafnos 1 Capsule contains Tacrolimus, a key component that suppresses the activity of immune cells responsible for attacking foreign substances in the body. By inhibiting these cells, Tacrolimus helps prevent organ rejection in transplant patients. It is advised to take Grafnos 1 Capsule as prescribed by the doctor for the specified duration. Side effects such as nausea, diarrhoea, headache, kidney problems, and high blood pressure may occur, but most often resolve over time without medical intervention.

Individuals allergic to Tacrolimus or any other medicines should inform their doctors before taking Grafnos 1 Capsule. Alcohol consumption should be avoided while on this medication, and driving should be done cautiously due to possible vision problems or nervous disturbances. Inform your doctor before vaccination, as Grafnos 1 Capsule may heighten infection risk or skin cancer due to its immune-suppressing effects.


Benefits

Grafnos 1 Capsule is a vital medicine that offers significant benefits in the prevention of organ rejection in transplant patients. When someone undergoes an organ transplant, there is a risk of organ rejection, where the body's immune system mistakes the new organ as a threat and launches an attack against it. Grafnos 1 Capsule, which contains Tacrolimus, functions as an immunosuppressant. It works by weakening the immune response that would normally fight off infections, thereby reducing the likelihood of the body rejecting the transplanted organ.


By targeting and suppressing the activity of T and B lymphocytes, which are essential components of the immune system responsible for identifying and attacking foreign invaders, Grafnos 1 Capsule plays a crucial role in helping the body accept the new organ. This action helps in protecting the transplanted organ and significantly reduces the chances of organ rejection in patients who have undergone transplant surgeries. It is essential to continue taking Grafnos 1 Capsule as prescribed by your doctor to ensure the success of the transplant operation.


In summary, Grafnos 1 Capsule is a valuable medication that, when used in combination with other medicines, enhances the likelihood of a successful transplant operation by effectively suppressing the immune response and safeguarding the transplanted organ from rejection. It offers transplant patients the opportunity to lead healthier lives post-surgery by ensuring the acceptance of the new organ and promoting better long-term outcomes. It is crucial to follow your doctor's recommendations and not discontinue the medication without medical advice to optimize the benefits of Grafnos 1 Capsule in preventing organ rejection.


How to use the Grafnos 1 Capsule

To use Grafnos 1 Capsule, follow your doctor's instructions carefully. Take the capsule on an empty stomach. Swallow the capsule whole with water, without crushing, breaking, or chewing it. If you have granules instead of a capsule, mix them with water to create an oral suspension. Drink the suspension right after preparing it; do not save it for later use. Always take the medicine as per the prescribed dose and duration to get the best results. If you have any questions about how to use Grafnos 1 Capsule, consult your doctor or pharmacist for guidance.


Uses of Grafnos 1 Capsule

The Grafnos 1 Capsule is primarily used to prevent organ rejection in transplant patients. This medication helps in stopping the body from rejecting transplanted organs, making it a crucial treatment for individuals who have undergone organ transplantation. By taking the Grafnos 1 Capsule as prescribed, patients can increase the chances of their new organs being accepted by their bodies and avoid the complications associated with organ rejection. This usage highlights the importance of Grafnos 1 Capsule in maintaining the health and well-being of transplant recipients.


What conditions Grafnos 1 Capsule treats?

Organ rejection happens when your body's defense system views a transplanted organ as unfamiliar and works to get rid of it. This rejection may occur swiftly (hyperacute), within the early months (acute), or later on (chronic). Symptoms can differ depending on the type of transplant you received, but pain, fever, or general sickness are common signs that you should promptly report to your doctor.


Should you consult a doctor?

If you are taking Grafnos 1 Capsule, it is important to seek medical attention if you experience certain symptoms. Contact your doctor immediately if you notice increased blood glucose levels, kidney damage, or persistent insomnia, tremors, high blood pressure, or signs of infection. These side effects require urgent medical attention as they may indicate serious complications that need to be addressed promptly. It is crucial to inform your healthcare provider about any concerning symptoms you may be experiencing while taking this medication to ensure proper management and monitoring of your health. Remember to follow your doctor's guidance closely, attend regular medical check-ups, and report any unusual or persistent side effects for timely intervention.


Side effects of Grafnos 1 Capsule

When taking Grafnos 1 Capsule, you may experience some side effects. Although most side effects are usually temporary and may go away as your body gets used to the medication, it is important to talk to your doctor if you have concerns or if the symptoms persist. Some potential side effects include increased glucose levels in the blood, kidney damage, insomnia (difficulty sleeping), tremors, high blood pressure, and the risk of infections. Additionally, you may also experience nausea, diarrhea, headache, constipation, fever, and kidney problems. It is essential to monitor your symptoms carefully and consult with your healthcare provider if you have any worries or if the side effects become troublesome.


Safety advice

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liver

When taking Grafnos 1 Capsule, it is important to be cautious if you have liver disease. Patients with liver issues may require adjustments to the dosage of the capsule. It is highly recommended to consult your doctor before using Grafnos 1 Capsule to ensure the appropriate dosage and safety for your liver health.

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kidney

Grafnos 1 Capsule requires caution in patients with kidney disease. Dosage adjustment might be necessary. Please consult your doctor.

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alcohol

It is not recommended to drink alcohol while taking Grafnos 1 Capsule due to safety concerns.

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driving

When taking Grafnos 1 Capsule, be cautious while driving as it may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if experiencing these symptoms.

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pregnancy

Grafnos 1 Capsule could potentially be harmful during pregnancy based on animal studies. Limited human studies are available. Consult your doctor for a personalized assessment considering the risks and benefits before using this medication.

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breastfeeding

**Safety Advice - Breastfeeding** Grafnos 1 Capsule is considered unsafe during breastfeeding. Limited data suggests it may pass into breastmilk and harm the baby.


Consumption warning before consuming Grafnos 1 Capsule

Before taking Grafnos 1 Capsule, it's important to inform your doctor if you have any allergies to Tacrolimus or other medications. If you are pregnant or breastfeeding, consult your doctor before using this medication. It is advised to avoid consuming alcohol while on Grafnos 1 Capsule. Be cautious when driving as this medication may cause vision issues or nervous disturbances in some individuals. Notify your doctor if you are due to receive a vaccination while taking Grafnos 1 Capsule. This medication can lower your body's immune defenses, potentially increasing the risk of infections or skin cancer. When outdoors, protect yourself by wearing appropriate clothing and using sunscreen. To prepare the oral suspension, use glass or metal materials and avoid plastics as granules can stick, affecting the dose. If accidental contact occurs with the skin, wash the area thoroughly with soap and water. Rinse eyes with plain water if contact happens.


What if you forgot to take Grafnos 1 Capsule?

If you forget to take a dose of Grafnos 1 Capsule, try to take it as soon as you remember. But if it's nearly time for your next scheduled dose, it's better to skip the missed dose and continue with your usual dosing routine. Remember not to take a double dose to make up for the missed one. It's important to stay consistent with your medication schedule.


Additional Information

Habit FormingNo
Chemical ClassMacrolide Lactams
Therapeutic Class-
Action ClassImmunosuppressant- Calcineurin inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Content verified by

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024