Gonal-F 450IU Injection

By Gonal-F

Rx

0ml Injection in a Pre-filled pen

Composition icon

Composition

Recombinant follicle stimulating hormone(450IU)

Manufacturer - Merck Ltd icon

Manufacturer - Merck Ltd

L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Expires on or after icon

Expires on or after

December, 2025

About Gonal-F 450IU Injection

Gonal-F 450IU Injection is a medication used to treat infertility in women and male hypogonadism, which refers to delayed puberty and low sperm count in men. The injection works by stimulating the release of eggs from the ovary in women and by increasing testosterone levels in men.

This fertility drug belongs to a group of medicines known as gonadotropins, which are hormones involved in reproduction and fertility. Female infertility is diagnosed when a woman is unable to conceive after a year of trying, which may also include experiencing miscarriages or stillbirths. Gonal-F 450IU Injection contains Follitropin alfa, which helps in developing and maturing multiple follicles containing eggs, ultimately aiding in the ovulation process necessary for fertilization to occur.

It is crucial to follow the doctor's instructions when using Gonal-F 450IU Injection. The dosage and frequency of administration will be determined by the healthcare provider based on the specific condition being treated. It is essential to take the medication for the prescribed duration to achieve the desired results.

Common side effects of Gonal-F 450IU Injection may include allergic reactions, headaches, breast swelling in males, and acne. If these side effects become bothersome or severe, it is important to inform your doctor promptly as they may provide guidance on managing or preventing them.

Before starting Gonal-F 450IU Injection, inform your doctor if you have a history of heart disease, ovarian cysts, or thyroid gland disorder. Additionally, disclose all other medications you are taking as some may interact with Gonal-F 450IU Injection, potentially affecting its efficacy or mode of action. Pregnant or breastfeeding women should avoid using this medication, and it is advisable to abstain from alcohol consumption or follow any dietary recommendations provided by the doctor while undergoing treatment.


Benefits

Gonal-F 450IU Injection offers several key benefits in the treatment of infertility in both men and women. In women dealing with infertility, this injection plays a crucial role in the normal development of eggs within the ovaries. By stimulating the release of healthy and matured eggs, Gonal-F 450IU Injection significantly enhances the chances of a successful pregnancy. This is particularly beneficial for women undergoing assisted reproductive technologies, where multiple follicles need to be developed and ripened for fertilization to occur. Additionally, in cases of anovulation and oligo-ovulation, where egg production is impaired, Gonal-F 450IU Injection helps to induce ovulation, thereby increasing the likelihood of conception.

For men suffering from male hypogonadism, a condition characterized by underactive testes leading to insufficient production of sex hormones required for fertility, Gonal-F 450IU Injection acts as a substitute for testosterone. By boosting sperm production, this injection effectively addresses infertility issues in men with hypogonadism. Following the doctor's instructions diligently is essential to fully benefit from the effects of Gonal-F 450IU Injection in restoring hormonal balance and enhancing fertility in both men and women.

In summary, Gonal-F 450IU Injection serves as a valuable treatment option for individuals struggling with infertility, offering a targeted approach to enhancing egg development in women and sperm production in men. By leveraging the properties of Follitropin alfa, this injection plays a crucial role in promoting reproductive health and increasing the chances of achieving a successful pregnancy.


How to use the Gonal-F 450IU Injection

To use Gonal-F 450IU Injection, it is important to understand that only a doctor or nurse should administer this medicine. The medication comes in a Prefilled Cartridge and will be given to you by a healthcare professional. It is crucial not to try to self-administer this injection. Follow the instructions of your healthcare provider carefully and do not attempt to use it on your own. Always seek guidance from a medical professional for the proper administration of Gonal-F 450IU Injection to ensure your safety and effectiveness of the treatment.


Uses of Gonal-F 450IU Injection

Gonal-F 450IU Injection is utilized in the treatment of female infertility and male hypogonadism. It provides assistance to women who are facing challenges in conceiving by addressing issues that hinder the natural conception process. Additionally, it is beneficial for men experiencing hypogonadism, a condition where the testes do not produce enough testosterone, leading to various health concerns. By addressing these specific concerns, Gonal-F 450IU Injection plays a crucial role in helping both women and men overcome their fertility-related challenges and hormone imbalances.


What conditions Gonal-F 450IU Injection treats?

Female infertility is diagnosed when a woman is unable to conceive after a year of trying without contraception. Causes include ovulation disorders, fallopian tube damage, and uterine or cervical issues. Risk factors may include age, obesity, smoking, alcohol use, and sexually transmitted infections. Hypogonadism is a condition where the gonads don't produce enough sex hormones, leading to issues with secondary sexual characteristics. This can be caused by autoimmune disorders, genetic conditions, infections, pituitary problems, or inflammatory diseases.


Should you consult a doctor?

If you experience an allergic reaction at the injection site, persistent headache, acne, sudden swelling of breast in males, abdominal pain, gastrointestinal discomfort, ovarian cysts, or a rash while using Gonal-F 450IU Injection, it is important to seek medical advice promptly. Additionally, if you have a history of heart disease, ovarian cysts, or thyroid gland disorder, inform your doctor before starting the medication. It's crucial to keep your healthcare provider informed about all medications you are currently taking, as some may interact with Gonal-F 450IU Injection. If you are pregnant, breastfeeding, or have concerns about potential side effects, consultation with your doctor is recommended. In case any side effects seem severe or bothersome, contacting your doctor is essential to discuss possible solutions. Remember to follow your doctor's guidance on lifestyle factors like diet modifications and alcohol consumption during the course of treatment.


Side effects of Gonal-F 450IU Injection

When using Gonal-F 450IU Injection, some individuals may experience side effects, although most of them are typically mild and temporary. These side effects can include an allergic reaction at the injection site, headaches, acne, swelling of the male breast tissue, abdominal pain, gastrointestinal discomfort, ovarian cysts, and skin rash. Some individuals may also experience pain or redness at the injection site. It is important to note that these side effects usually do not require immediate medical attention and often improve as the body gets used to the medication. However, if these side effects persist or cause concern, it is advisable to consult a healthcare provider for further guidance.


Safety advice

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liver

Limited information is available regarding the use of Gonal-F 450IU Injection in patients with liver disease. It is advisable to consult your doctor before using this medication to ensure that it is safe and appropriate for your liver condition. Your healthcare provider will be able to provide guidance tailored to your specific situation.

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kidney

Limited information is available on using Gonal-F 450IU Injection for patients with kidney disease. It's best to consult your doctor for guidance.

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alcohol

When taking Gonal-F 450IU Injection, be cautious when drinking alcohol. It is recommended to seek advice from your doctor.

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driving

Gonal-F 450IU Injection generally does not impact your driving ability.

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pregnancy

Gonal-F 450IU Injection is not recommended during pregnancy due to potential harm to the developing baby based on studies in pregnant women and animals. Consult your doctor before usage.

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breastfeeding

It is better to consult your doctor before using Gonal-F 450IU Injection.


Consumption warning before consuming Gonal-F 450IU Injection

Before consuming Folisurge 900IU/1.44 ml Prefilled Cartridge 1's, be aware of potential risks. This medication may lead to ovarian hyperstimulation syndrome (OHSS), causing enlarged ovarian cysts. If you experience unusual pain, sudden weight gain, breathing difficulties, or nausea, alert your healthcare provider immediately. Folisurge 900IU/1.44 ml Prefilled Cartridge 1's can also heighten the chances of multiple pregnancies, birth defects, ectopic pregnancy, and miscarriage. To monitor these risks, your doctor may recommend regular blood tests and ultrasounds during treatment. Inform your doctor about any history of blood clots or previous infertility treatments, as Folisurge 900IU/1.44 ml Prefilled Cartridge 1's could increase clotting risks and tumor development. Watch out for signs like fragile skin, blisters, or pain in the stomach, arms, or legs. Not suitable for women with primary ovarian failure.


Disease interactions

When considering the use of Gonal-F 450IU Injection, it is important to be cautious in patients with certain medical conditions. Gonal-F 450IU Injection should not be administered to individuals with adrenal dysfunction, thyroid dysfunction, ovarian cysts, or tumors in the ovaries, womb, or breast. These conditions may interact with the medication and could potentially lead to adverse effects. Therefore, it is essential to consult with a healthcare provider before using Gonal-F 450IU Injection if you have any of these medical issues. It is crucial to prioritize your health and safety when using this medication.


What if you forgot to take Gonal-F 450IU Injection?

If you happen to miss a dose of Gonal-F 450IU Injection, it is important to promptly seek advice from your doctor regarding the best course of action. Consulting with your healthcare provider allows for proper guidance on how to proceed after a missed dose.


Related lab tests

When considering related lab tests for Gonal-F 450IU Injection, healthcare providers may look at certain important markers to assess various aspects of a patient's health. These lab tests can provide valuable information about different hormones and blood sugar levels that may be impacted by the medication. Some relevant lab tests to consider include the following:

1. Anti Mullerian Hormone (AMH) test: This test measures the levels of AMH in the blood, which can provide insights into ovarian reserve and fertility potential in women.

2. Follicle Stimulating Hormone (FSH) test: FSH levels can indicate the function of the ovaries and testes, helping to assess reproductive health and potential issues.

3. Glycosylated Hemoglobin (HbA1c) test: This test provides an average of a person's blood sugar levels over the past two to three months, giving an indication of long-term blood sugar control.

4. Testosterone Free and Total tests: These tests measure levels of testosterone in the blood, which is essential for assessing hormonal balance, particularly in men.

5. Thyroid Stimulating Hormone (TSH) test: TSH levels help to evaluate thyroid function and can indicate conditions such as hypothyroidism or hyperthyroidism.

By considering these related lab tests alongside the use of Gonal-F 450IU Injection, healthcare providers can gain a comprehensive understanding of a patient's hormonal and metabolic status to guide treatment and monitor any potential effects of the medication.


Additional Information

Habit FormingNo
Chemical ClassGonadotropins
Therapeutic ClassGYNAECOLOGICAL
Action ClassGonadotropins

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025