Folitrax 25 Tablet
By Folitrax
Rx
4 Tablet in a Strip

Composition
Methotrexate(25mg)

Manufacturer - Ipca Laboratories Ltd
142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Expires on or after
September, 2027
About Folitrax 25 Tablet
Folitrax 25 Tablet is a medication used to treat various conditions such as cancer affecting different parts of the body like the breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also prescribed for rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease. The medicine can be taken alone or in combination with other medications as directed by the doctor. Proper dosage is crucial to avoid severe side effects, and it may take some time before the benefits are noticeable. Alcohol consumption should be avoided while taking Folitrax 25 Tablet due to the risk of liver damage.
The most common side effects of Folitrax 25 Tablet include ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Patients may be advised to take folic acid to mitigate some of these effects. If the side effects persist or worsen, it is important to inform the doctor. Regular monitoring through blood tests, X-rays, and physical examinations might be necessary to check for any potential issues with blood, liver, or kidneys during treatment.
Folitrax 25 Tablet, belonging to the class of anti-metabolites and immunosuppressants, is effective in treating active rheumatoid arthritis, severe psoriasis, psoriatic arthritis, and various types of cancers including breast cancer, lung cancer, and lymphomas. The key component of Folitrax 25 Tablet is Methotrexate, which works by reducing inflammation in joint tissues, alleviating pain, and slowing down joint damage progression. It also inhibits the growth of cancer cells. For psoriasis, Folitrax 25 Tablet suppresses the overactive immune response responsible for the condition.
Common side effects of Folitrax 25 Tablet may include nausea, vomiting, fatigue, dizziness, and changes in blood cell counts. It is important to follow the prescribed dosage precisely to avoid serious toxic effects. Pregnant or breastfeeding women should not take this medication. Driving should be done with caution due to potential dizziness and fatigue. Regular monitoring with blood tests and other examinations may be necessary. Patients are advised to inform their healthcare provider about all medications and health conditions to avoid any adverse interactions.
Additionally, FOLITRAX 25MG TABLET, containing Methotrexate, falls under the category of Antimetabolites and is used to manage psoriasis, psoriatic arthritis, mycosis fungoides, and rheumatoid arthritis. Prior to taking FOLITRAX 25MG TABLET, it is essential to disclose medical history and current medications to the doctor. This medication is not recommended for pregnant, nursing women, those planning pregnancy, heavy alcohol consumers, or individuals with liver and kidney issues. Special caution is advised for patients with lung disorders, blood disorders, and gastric problems. Side effects may include headache, nausea, vomiting, dizziness, and changes in blood cell levels.
Benefits
Folitrax 25 Tablet offers multiple benefits in treating various medical conditions. When used in cancer treatment, Folitrax 25 Tablet effectively slows down the growth of cancer cells in the body. It is commonly prescribed for treating acute leukemias, non-Hodgkin’s lymphoma, and solid tumors in various parts of the body such as breast, lung, bladder, head and neck, cervical, ovarian, and testicular cancer. This medication can be given on its own or combined with other treatments as recommended by a healthcare provider. Folitrax 25 Tablet is a potent medication that requires a discussion of its risks and benefits with a doctor. It is crucial to avoid alcohol consumption during the treatment and ensure proper hydration by drinking plenty of water.
In rheumatoid arthritis and psoriasis treatment, Folitrax 25 Tablet, classified as an antimetabolite, plays a significant role. For severe cases where other treatments have been ineffective, Folitrax 25 Tablet can help in managing symptoms and improving quality of life. By reducing the body's immune response, this medication decreases swelling, pain, and stiffness, thereby enhancing joint function. For psoriasis, which involves rapid skin cell growth, Folitrax 25 Tablet works by targeting and eliminating these excessive cells. It is essential to strictly adhere to the prescribed dosage and duration for optimal benefits. While awaiting its full effectiveness in several months, patients should refrain from exceeding the recommended dosage and maintain adequate hydration by consuming water and avoiding alcohol.
Moreover, Folitrax 25 Tablet is also beneficial in the treatment of Crohn’s disease, a chronic inflammatory condition affecting the intestines. Common symptoms include abdominal pain and diarrhea, which can be alleviated by reducing inflammation with Folitrax 25 Tablet. By relieving symptoms and preventing their recurrence, this medication aids in managing the condition effectively. The versatility of Folitrax 25 Tablet extends to treating inflammatory bowel disease, showcasing its efficacy in addressing diverse medical needs.
How to use the Folitrax 25 Tablet
To use Folitrax 25 Tablet, follow the instructions provided by your doctor carefully. Take the tablet in the dose and duration as prescribed, without chewing, crushing, or breaking it. You can take Folitrax 25 Tablet with or without food, but it is recommended to take it at the same time each day for better results.
If you are prescribed Folitrax 25 Tablet, take it exactly as directed by your doctor. For tablets or capsules, take it one hour after food in the evening or as advised. Swallow the tablet/capsule whole with a glass of water while standing or sitting upright; do not break or chew it. Alternatively, if you are using the oral solution, take the prescribed quantity by mouth using the dosing syringe provided.
Remember to take Folitrax 25 Tablet Tablet as per your physician's advice. Swallow the tablet with a full glass of water, without crushing or chewing it. Your doctor will determine the right dose and duration based on factors like your age, body weight, and the specific condition being treated. If you have any questions or concerns about how to use Folitrax 25 Tablet, always consult your healthcare provider for guidance.
Uses of Folitrax 25 Tablet
Folitrax 25 Tablet is used in the treatment of various conditions such as cancer, rheumatoid arthritis, psoriasis, and Crohn’s disease. It is effective in managing symptoms and improving the overall health of individuals with these health issues. For cancer patients, Folitrax 25 Tablet is utilized as a part of the treatment regimen to help combat the disease. In the case of rheumatoid arthritis, psoriasis, and psoriatic arthritis, this medication aids in reducing inflammation and pain, thus enhancing the quality of life for individuals with these conditions. Additionally, Folitrax 25 Tablet is prescribed for patients suffering from Crohn’s disease to alleviate symptoms and promote better gastrointestinal health. With its versatile uses in treating a range of conditions, Folitrax 25 Tablet plays a crucial role in the healthcare industry.
What conditions Folitrax 25 Tablet treats?
Folitrax 25 Tablet is used to treat rheumatoid arthritis, an autoimmune disease causing joint pain and inflammation. It is also effective for psoriatic arthritis, related to psoriasis, which affects joints in lower extremities. Additionally, it helps in managing psoriasis, a skin condition with symptoms like red, scaly patches and joint pain. Folitrax 25 Tablet may assist in the treatment of these conditions by addressing inflammation and discomfort associated with them.
Should you consult a doctor?
It is crucial to seek medical advice when taking Folitrax 25 Tablet if you have any of the following conditions: blood disorders, impaired immune system, ongoing or past infections, ulcers in the gastrointestinal tract, or are currently receiving live vaccine vaccinations. Additionally, before starting this medication, inform your doctor if you have diabetes, mental health conditions, are undergoing radiotherapy, or are scheduled for surgery involving general anesthesia. Seek immediate medical attention if you experience any unexpected or severe symptoms while taking Folitrax 25 Tablet to ensure your safety and well-being.
Side effects of Folitrax 25 Tablet
Folitrax 25 Tablet may cause several side effects, which typically subside as your body gets used to the medication. However, if these effects persist or cause concern, it is important to consult your doctor. Some common side effects include ulcerative stomatitis, nausea, abdominal pain, increased liver enzymes, hair loss, and decreased blood cells such as red cells, white cells, and platelets. Other possible side effects may include vomiting, diarrhea, unusual fatigue, dizziness, headache, loss of appetite, tingling sensation, lowered resistance to infections, soreness of mouth and lips, and formation of lumps accompanied by back pain, weight loss, and night sweats.
In more severe cases, side effects may manifest as bleeding from the nose, formation of blisters and skin peeling, ulcers in the vagina (in women), inflammation and ulcerations in the mouth, rash, reddening of the skin, increased itchiness, lung disorders, sensitivity to light, swelling of the mouth, anorexia, elevated blood sugar, viral skin rash, depression, confusion, decreased blood pressure, blood clots in veins, breathing difficulties, lung disease, abdominal pain, dehydration, fever, acne, hives, muscle and joint pain, loss of sexual interest, menstrual disorders, asthma, vision disturbances, mood fluctuations, heart inflammation, thromboembolic complications, and pericardial tamponade.
If you experience more severe symptoms such as infection, sore throat, mouth ulcers, fever, chills, lung inflammation with breathlessness, blistering of the skin, Stevens Johnson syndrome, skin rash with fever, loss of co-ordination, weakness on one side of the body, convulsions, yellowing of skin, swelling in hands or feet, miscarriage, fetal damage, chest pain, bleeding, or signs of shock, seek immediate medical attention and discontinue the use of Folitrax 25 Tablet.
Safety advice

liver
When using Folitrax 25 Tablet, it is important to be cautious if you have liver disease. It may be necessary to adjust the dosage of the tablet in such cases. It is advisable to seek guidance from your doctor regarding the use of Folitrax 25 Tablet if you have liver issues.

kidney
Folitrax 25 Tablet should be used carefully in individuals with kidney disease. Dose adjustment may be necessary. Regular kidney function tests are recommended during the course of this medication.

alcohol
It is unsafe to consume alcohol with Folitrax 25 Tablet.

driving
Folitrax 25 Tablet can reduce alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these effects.

pregnancy
Folitrax 25 Tablet is not safe to use during pregnancy. Consult your doctor as studies have shown harmful effects on the developing baby in pregnant women and animals.

breastfeeding
Folitrax 25 Tablet is not safe to use while breastfeeding. Studies indicate potential harm to the baby due to possible toxicity.
Age above 75(Geriatrics)
Folitrax 25 Tablet is recommended to be administered with caution and in a lower dosage to elderly patients due to diminished function of the liver and kidneys and reduced folate levels in the blood. Consult the doctor before taking Folitrax 25 Tablet.
Age below 6 months(Pediatrics)
Folitrax 25 Tablet is not recommended to be taken by children below the age of 3 years due to a lack of safety data. Consult your doctor before taking the medicine.
Consumption warning before consuming Folitrax 25 Tablet
Before consuming Folitrax 25 Tablet, it is crucial to consider certain factors to ensure your safety and well-being. Do not take this medication if you are allergic to any of its components or if you have specific health conditions such as immunodeficiency, bone marrow problems, low blood cell counts, anaemia, liver issues due to alcohol abuse, chronic liver disease, pregnancy, or breastfeeding. Prior consultation with your healthcare provider is essential if you have a history of liver or kidney problems, stomach or bowel ulcers, poor health condition, recent vaccinations or upcoming vaccination schedules, diabetes, fluid accumulation in the stomach or lungs, or if you experience dizziness and fatigue. It is important to strictly adhere to the prescribed dosage and duration to avoid potential serious complications. If you encounter symptoms like mouth sores, diarrhoea, fever, dehydration, cough, bleeding, breathing difficulties, signs of infection, or skin rashes while taking Folitrax 25 Tablet, stop the medication immediately and seek medical advice promptly.
Disease interactions
When considering the use of Folitrax 25 Tablet, it is crucial to disclose any existing immunodeficiency conditions, bone marrow issues, low white blood cell count, low platelet count, significant anaemia, liver problems related to alcohol misuse, or chronic liver disease to your healthcare provider. These factors can impact the way this medication works in your body and may influence its effectiveness and safety. Keeping your doctor informed about your medical history allows for a comprehensive assessment of potential disease drug interactions and ensures appropriate monitoring throughout your treatment.
What if you forgot to take Folitrax 25 Tablet?
If you forget to take a dose of Folitrax 25 Tablet, try to take it as soon as you remember. But if it's almost time for your next scheduled dose, just skip the missed dose and resume your usual dosing routine. It's important not to take a double dose to make up for the missed one. Remember to follow the recommended dosing schedule for your Folitrax 25 Tablet to ensure the best results from your medication.
What happens if you take overdose of Folitrax 25 Tablet?
If too much Folitrax 25 Tablet is taken, it is advised to seek immediate medical advice. Signs of overdosing onFolitrax 25 Tabletinclude heightened susceptibility to bruising or bleeding, nausea, vomiting, feeling unusually weak, and the occurrence of mouth sores and ulcers.
Related lab tests
For individuals taking Folitrax 25 Tablet, it is important to monitor certain lab tests to ensure the medication is effective and not causing any adverse effects. Related lab tests that may be recommended include:
1. Anti Saccharomyces Cerevisiae (ASCA), IgA and IgG: These tests can help in the diagnosis and monitoring of inflammatory bowel diseases like Crohn's disease and ulcerative colitis, which can sometimes be associated with the use of Folitrax 25 Tablet.
2. Rheumatoid Factor - Agglutination and Turbidometry: These tests are often used in the assessment and monitoring of rheumatoid arthritis, a condition for which Folitrax 25 Tablet is commonly prescribed.
3. Rheumatoid Factor IgG Antibody: This test helps in detecting the presence of antibodies that may be associated with autoimmune conditions like rheumatoid arthritis, which could be influenced by the use of Folitrax 25 Tablet.
In addition to these specific tests, individuals taking Folitrax 25 Tablet may also need to undergo routine lab investigations such as:
- Complete Blood Count (CBC)/ Hemogram: This test provides important information about various blood components including red blood cells, white blood cells, and platelets, which can be affected by certain medications like Folitrax 25 Tablet.
- Liver Function Test (LFT): This test assesses the health and function of the liver, as medications like Folitrax 25 Tablet can sometimes affect liver enzymes.
- Kidney Function Test (KFT): This test evaluates how well the kidneys are functioning and is important for monitoring any potential kidney-related side effects of medications like Folitrax 25 Tablet.
Regular monitoring of these lab tests can help healthcare providers ensure the safe and effective use of Folitrax 25 Tablet in managing the respective conditions for which it is prescribed.
Additional Information
Habit Forming | No |
Chemical Class | Glutamic Acid Derivatives |
Therapeutic Class | ANTI NEOPLASTICS |
Action Class | Antimetabolite- Methotrexate |
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024