Espazine 1mg Injection
By Espazine
Rx
1ml Injection in a Vial

Composition
Trifluoperazine(1mg)

Manufacturer - Glaxo SmithKline Pharmaceuticals Ltd
Dr. Annie Besant Road, Mumbai - 400 030

Expires on or after
July, 2026
About Espazine 1mg Injection
Espazine 1mg Injection is a medication used in the treatment of schizophrenia, a mental disorder affecting a person's thoughts, mood, and behavior. This injection works by altering thoughts and elevating mood to improve the individual's ability to think, feel, and behave. It is administered as an injection under the supervision of a healthcare professional and should not be self-administered. It is essential to take Espazine 1mg Injection at the same time each day to maintain a consistent level of the medicine in the body. It is crucial to follow the dosage and duration as advised by your doctor and not to skip any doses, even if feeling better.
Common side effects of Espazine 1mg Injection may include dry mouth, abnormal voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, it may cause a sudden drop in blood pressure, so it is advised to change positions slowly. It may also cause dizziness and sleepiness, so avoiding tasks requiring mental focus until effects are understood is important. Weight gain may occur, thus following a healthy diet and exercising regularly is recommended. Temporary injection site reactions such as pain, redness, or swelling may occur but usually resolve on their own.
Before taking Espazine 1mg Injection, inform your doctor if you have thyroid or kidney problems, epilepsy, Parkinson's disease, glaucoma, or heart problems. Avoid consumption of alcohol or sleep-inducing medications while on this treatment. Additionally, if allergy medication or cough medications are being taken, consult with your healthcare provider. Weight gain is a possible side effect, thus maintaining a balanced diet and regular exercise routine is essential for managing it.
Benefits
Espazine 1mg Injection offers several benefits in the treatment of schizophrenia. Schizophrenia is a mental disorder characterized by abnormal thinking, feelings, and behavior. This medication works by restoring the chemical imbalances in the brain that contribute to these changes. By inhibiting dopamine receptors in the brain, Espazine 1mg Injection helps in improving thoughts, behavior, and overall quality of life for individuals with schizophrenia. It not only prevents and treats relapses of schizophrenia but can also be beneficial in managing anxiety and depression over a short period, as well as symptoms like nausea and vomiting. Dopamine plays a crucial role in regulating mood, behavior, and emotions, and Espazine 1mg Injection helps in controlling psychotic illness, relieving depression, lightening the mood, and alleviating anxiety symptoms such as fear and panic. Furthermore, by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) and inhibiting the transmission of signals to the vomiting center, Espazine 1mg Injection effectively controls nausea and vomiting. Overall, Espazine 1mg Injection is a valuable medication that not only addresses the symptoms of schizophrenia but also provides relief from related conditions like anxiety, depression, nausea, and vomiting, ultimately improving the well-being of individuals living with these challenges.
How to use the Espazine 1mg Injection
When using Espazine 1mg Injection, always remember not to self-administer it. This medicine should only be given to you by your doctor or nurse. For the tablet form, follow your doctor's instructions on whether to take it with or without food. Swallow the tablet whole with a glass of water and avoid breaking, crushing, or chewing it. If you are prescribed the syrup, shake the bottle well before use. Take the recommended dose by mouth using the measuring cup, dosing syringe, or dropper provided in the pack. Adhering to these instructions will help ensure the safe and effective use of Espazine 1mg Injection.
Uses of Espazine 1mg Injection
Espazine 1mg Injection is primarily used in the treatment of schizophrenia. It helps in managing symptoms associated with schizophrenia such as hallucinations, delusions, and disorganized thinking. This medication can also be effective in alleviating symptoms of anxiety and depression in some cases. Additionally, Espazine 1mg Injection is sometimes prescribed to control nausea and vomiting, providing relief to individuals experiencing these symptoms.
What conditions Espazine 1mg Injection treats?
Espazine 1mg Injection is commonly used to treat conditions such as schizophrenia, anxiety, and depression. Schizophrenia is a mental disorder that can affect a person's ability to think clearly and behave normally, leading to symptoms like hallucinations, delusions, and difficulty in daily activities. Anxiety is a mental health disorder characterized by excessive worry and fear that can disrupt daily life, while depression is a mood disorder that can cause feelings of sadness and loss of interest in activities. Espazine 1mg Injection can help manage these conditions effectively.
Should you consult a doctor?
If you experience persistent side effects such as orthostatic hypotension (sudden lowering of blood pressure on standing), excessive sleepiness, dry mouth, abnormal voluntary movements, weight gain, increased prolactin levels, urinary retention, constipation, muscle stiffness, tremors, or injection site reactions that do not improve or are concerning, it is important to consult your doctor. Additionally, if you have underlying health conditions like thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or heart issues, or if you are taking alcohol or medications that induce sleep, cough, or allergies, seek medical advice before using Espazine 1mg Injection. It is crucial not to stop this medication abruptly without medical guidance, as it may exacerbate symptoms. If you notice any unusual changes or have questions about your treatment, always consult a healthcare professional for assistance.
Side effects of Espazine 1mg Injection
When using Espazine 1mg Injection, some people may experience side effects. Most of these side effects are not severe and tend to fade away as your body gets used to the medication. However, it's essential to talk to your doctor if these effects persist or if you are concerned about them.
Some common side effects of Espazine 1mg Injection include orthostatic hypotension, which is a sudden drop in blood pressure when standing up. This may lead to dizziness or fainting. Another common side effect is sleepiness, making you feel tired or sluggish. You might also experience dryness in your mouth, which can be bothersome.
In some cases, Espazine 1mg Injection may cause abnormal voluntary movements, muscle stiffness, or tremors. These effects can impact your daily activities and should be reported to your healthcare provider. Additionally, weight gain and increased prolactin levels in the blood are potential side effects that can occur with this medication.
Other possible side effects of Espazine 1mg Injection include urinary retention, constipation, muscle weakness, and injection site reactions like pain, swelling, or redness. Some people may also notice restlessness, weakness, drowsiness, blurred vision, or dry mouth. Loss of appetite, confusion, water retention leading to swelling, and fainting upon standing up are also reported side effects of this medication.
It's crucial to monitor these side effects and consult with your doctor if you experience any of them while taking Espazine 1mg Injection. Your healthcare provider can provide guidance on managing these effects and adjusting your treatment plan if needed.
Safety advice

liver
Limited information is available regarding the use of Espazine 1mg Injection in individuals with liver disease. It is advised to consult your healthcare provider before use. Based on current data, Espazine 1mg Injection is not recommended for patients with liver disease due to safety concerns. Please seek medical advice before starting this medication if you have liver issues to ensure your safety and well-being.

kidney
Limited information is available on using Espazine 1mg Injection in patients with kidney disease. Please consult your doctor before use.

alcohol
Espazine 1mg Injection can increase drowsiness when taken with alcohol. Consult your doctor before consuming alcohol while using Espazine 1mg Injection.

driving
Espazine 1mg Injection can cause dizziness, drowsiness, and blurred vision, affecting driving ability. Be cautious when driving after using this medication.

pregnancy
Espazine 1mg Injection may not be safe during pregnancy. Animal studies show potential harm to the baby. Your doctor will assess risks versus benefits before prescribing. Please consult your doctor.

breastfeeding
Espazine 1mg Injection is likely unsafe during breastfeeding as it may pass into breastmilk and harm the baby.
Consumption warning before consuming Espazine 1mg Injection
Before consuming Espazine 1mg Injection, it is essential to consider certain precautions. Inform your doctor if you are allergic to Espazine 1 mg Tablet or any other medications. This medication is not suitable for children under 6 years old if in tablet form, and for those under 3 years if in syrup form. Pregnant women, especially in the third trimester, should avoid Espazine due to potential adverse effects on the baby, such as breathing problems or muscle stiffness. Nursing mothers should also consult a doctor before using Espazine. Caution should be exercised in elderly patients over 65 as they are at higher risk of adverse reactions. Avoid Espazine if you have certain conditions like blood disorders, liver problems, or heart circulation issues. Furthermore, refrain from consuming alcohol while taking Espazine as it may lead to severe consequences like dizziness, fainting, or irregular heartbeats. Inform your healthcare provider if you have specific conditions such as Parkinson’s disease, glaucoma, muscle weakness, prostate enlargement, dementia, high blood pressure, diabetes, or a family history of certain medical issues before taking Espazine 1mg.
Additional Information
| Habit Forming | No |
| Chemical Class | Phenothiazine Derivative |
| Therapeutic Class | NEURO CNS |
| Action Class | Typical Antipsychotics |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹28.1
Inclusive of all taxes
Content verified by

Dr. Monie Riju Simon
MBBS - General Medicine
Last update on 11-Feb-2025
