Espaze 40 Injection
By Espaze
Rx
1 Injection in a Vial

Composition
Esomeprazole(40mg)

Manufacturer - Agex Laboratories Pvt Ltd
g-8, manohara marg, wazirabad, sector 52, gurugram, haryana 122003

Expires on or after
July, 2026
About Espaze 40 Injection
Espaze 40 Injection is a medication designed to lessen the production of acid in the stomach. It is primarily utilized in the treatment of acid-related conditions affecting the stomach and intestines, such as acid reflux and other ailments linked to excess acid generation. This injection is classified under proton pump inhibitors (PPIs), a group of medications with a similar mode of action.
One of the key applications of Espaze 40 Injection is to prevent stress ulcers in severely ill patients. It is typically given before anesthesia to reduce the risk of complications related to aspiration. Unlike tablets, this medicine is administered directly into a vein by a healthcare professional. Your doctor will determine whether receiving the injection instead of taking a tablet is more appropriate for your current condition. The dosage of Espaze 40 Injection is individualized based on your specific medical situation and your response to the treatment. Furthermore, the duration of the treatment will be decided by your doctor.
To optimize the effectiveness of Espaze 40 Injection, it is advisable to consume smaller, more frequent meals and to avoid foods and beverages that can trigger increased acid production, such as caffeinated drinks, spicy, or fatty foods. Common side effects associated with this medication include reactions at the injection site, nausea, headaches, dizziness, flatulence, diarrhea, stomach discomfort, and fundic gland polyps. While these side effects are usually mild, it is important to consult your doctor if they persist or become bothersome.
There are certain individuals for whom Espaze 40 Injection is not suitable. Patients with severe liver issues, those taking HIV medications, individuals with a history of allergic reactions to similar drugs, or those experiencing bone loss (osteoporosis) should inform their doctor before starting this treatment. Pregnant or breastfeeding women should also seek advice from their healthcare provider before using this medicine. It is recommended to avoid alcohol consumption while using Espaze 40 Injection, as alcohol can exacerbate symptoms by stimulating excessive acid production in the stomach.
Benefits
Espaze 40 Injection is beneficial in the treatment of Gastroesophageal reflux disease (Acid reflux), which is a chronic condition causing persistent heartburn. It works by belonging to a group of medicines called proton pump inhibitors, which help reduce the production of stomach acid. By decreasing the acid levels in the stomach, this injection can provide relief from the discomfort and pain associated with heartburn and acid reflux. It is essential to follow the prescribed dosage instructions for the drug to be effective in managing symptoms.
In addition to the medication, making some simple lifestyle changes can also help alleviate the symptoms of GERD. By identifying and avoiding foods that trigger heartburn, consuming smaller and more frequent meals, maintaining a healthy weight, and finding ways to relax, individuals can complement the effects of Espaze 40 Injection. Furthermore, it is recommended not to eat anything within 3-4 hours before going to bed to reduce the likelihood of experiencing acid reflux during sleep.
Overall, the benefits of Espaze 40 Injection lie in its ability to reduce stomach acid production, providing relief from heartburn and acid reflux symptoms associated with Gastroesophageal reflux disease. When used in conjunction with lifestyle modifications, this medication can contribute to improved management of GERD, helping individuals lead a more comfortable and symptom-free life.
How to use the Espaze 40 Injection
When using Espaze 40 Injection, it is important to remember that only a doctor or nurse should administer this medication. It should not be self-administered. The injection is typically given directly into a vein by a healthcare professional. Your doctor will determine the appropriate dosage based on factors like your age, body weight, and the specific condition being treated. It is crucial to follow your doctor's instructions carefully and not attempt to use this injection on your own. Always rely on trained medical staff to administer Espaze 40 Injection to ensure its safe and effective use.
Uses of Espaze 40 Injection
Espaze 40 Injection is commonly used for various medical conditions. It is primarily used in the treatment of Gastroesophageal reflux disease (Acid reflux), a condition where stomach acid flows back into the esophagus, causing discomfort and irritation. This medication also proves to be effective in managing Gastroesophageal reflux disease (GERD), helping to alleviate symptoms and improve overall quality of life for individuals suffering from this ailment. In addition, Espaze 40 Injection is also used to treat stomach ulcers that are caused by NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), providing relief and promoting healing of the ulcers. Furthermore, this medication is prescribed to prevent rebleeding following therapeutic endoscopic procedures performed for acute bleeding stomach or intestinal ulcers. By following the recommended dosage and administration instructions, Espaze 40 Injection serves as a valuable tool in addressing these gastrointestinal disorders effectively.
What conditions Espaze 40 Injection treats?
Espaze 40 Injection is used to treat acid-related conditions in the stomach and intestine, such as acid reflux. Acid reflux is a chronic condition that causes heartburn due to stomach contents flowing back into the esophagus. This medicine, belonging to proton pump inhibitors, reduces stomach acid production, alleviating heartburn pain. Lifestyle changes like avoiding trigger foods, eating smaller meals, weight management, and relaxation techniques can also help manage acid reflux symptoms effectively. Make sure to follow your doctor's instructions for the medication to work optimally.
Should you consult a doctor?
You should consult a doctor before using Espaze 40 Injection if you have a history of skin reactions from acidity medications, need a Chromogranin A blood test, experienced unexplained weight loss, difficulty swallowing, stomach pain, indigestion, black stools indicating blood, or osteoporosis. If you experience any of these conditions, it is important to seek medical advice promptly for proper evaluation and guidance.
Side effects of Espaze 40 Injection
Espaze 40 Injection may cause various side effects, although most of them do not require medical attention and tend to fade as your body gets used to the medication. Some common side effects include a reaction at the injection site, headache, dizziness, dry mouth, nausea, abdominal pain, constipation, flatulence, and diarrhea. Other potential side effects may include swelling in the feet and ankles, disturbed sleep, tingling sensations, sleepiness, skin rash, fractures in joints like hip, wrist, or spine, and fundic gland polyps. More serious side effects that require immediate medical attention include significant unexplained weight loss, swallowing difficulties, stomach pain, vomiting (with or without blood), black stools, severe allergic reactions, skin reddening with blisters or ulcers, and yellowing of the skin along with dark urine and fatigue. If you experience any of these severe side effects, stop using the injection and consult your doctor promptly.
Safety advice

liver
For individuals with severe liver disease, it is important to use Espaze 40 Injection with caution. In such cases, dose adjustment may be necessary, and it is advised to consult your doctor for proper guidance. However, patients with mild to moderate liver disease do not typically require dose adjustment when using Espaze 40 Injection. It is essential to follow your healthcare provider's recommendations and seek their advice whenever needed.

kidney
Espaze 40 Injection should be used carefully in people with severe kidney disease. Consult your doctor as dose adjustment may be necessary. No adjustments are needed for mild to moderate kidney issues.

alcohol
When taking Espaze 40 Injection, it is important to be cautious when consuming alcohol. It is recommended to consult your doctor regarding alcohol intake while using this medication.

driving
While the impact of Espaze 40 Injection on driving is uncertain, avoid driving if you have symptoms affecting your focus or reactions. It is advised to consult a doctor if unsure.

pregnancy
Espaze 40 Injection may not be safe during pregnancy, as animal studies have suggested potential harm to the developing baby. Consult your doctor, as they will evaluate the benefits and risks before prescribing this medication to you.

breastfeeding
Espaze 40 Injection may not be safe for breastfeeding as limited data indicates it could pass into breastmilk and harm the baby.
Age above 75(Geriatrics)
Espaze 40 Injection should be used with caution in elderly patients (65 years and above). Consult your doctor before receiving Espaze 40 Injection
Age below 6 months(Pediatrics)
Espaze 40 Injection is not recommended for use in children aged less than 1 year of age. Your doctor will administer the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before receiving Espaze 40 Injection.
Consumption warning before consuming Espaze 40 Injection
Before receiving Espaze 40 Injection, it is important to consider certain warnings and precautions. This medicine is used to reduce stomach acid and treat conditions like acid reflux and excessive acid production in the stomach. It is also given to prevent stress ulcers in critically ill patients. Espaze 40 Injection belongs to a group of medicines called proton pump inhibitors and is administered by a healthcare professional through a vein. Your doctor will determine if an injection is suitable for you based on your condition.
Common side effects may include injection site reactions, nausea, headache, dizziness, flatulence, diarrhea, and stomach pain. If these side effects persist or are bothersome, consult your doctor. Additionally, discuss with your healthcare provider ways to prevent bone loss, such as taking calcium and vitamin D supplements. Some individuals should avoid this medication, such as those with severe liver problems, taking HIV medications, having a history of allergic reactions to similar drugs, or experiencing osteoporosis. Pregnant or breastfeeding women should also seek medical advice before using Espaze 40 Injection. It is advised to abstain from alcohol consumption as it can exacerbate stomach acid production.
What if you forgot to take Espaze 40 Injection?
If you forget to take a dose of Espaze 40 Injection, it is important to consult your doctor for guidance. It is crucial to follow their advice on how to proceed based on your individual health condition and treatment plan. Missing a dose may impact the effectiveness of the medication, so it is best to seek professional advice to ensure proper management. Your doctor can provide specific instructions on what to do if you miss a dose and how to maintain your treatment schedule.
What happens if you take overdose of Espaze 40 Injection?
When it comes to Espaze 40 Injection, it is important to note that it will be given to you exclusively by a healthcare professional in a hospital setting. This greatly reduces the risk of an overdose. If you notice any unusual symptoms after receiving this injection, it is crucial to speak with your doctor or nurse immediately for guidance. By ensuring proper communication with your healthcare provider, you can address any concerns or symptoms effectively.
Related lab tests
Related Lab Tests for Espaze 40 Injection could include a Complete Blood Count. This test gives information about different components of your blood, such as red blood cells, white blood cells, and platelets. It helps in diagnosing various conditions like anemia, infections, and bleeding disorders. By analyzing the results of a Complete Blood Count, healthcare providers can monitor the effects of using Espaze 40 Injection and ensure that the medication is working effectively for you.
Additional Information
| Habit Forming | No |
| Chemical Class | Sulfinylbenzimidazole Derivative |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Proton pump inhibitors |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹111
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Content verified by

Dr. Preeti Kumar
MBBS, DGO - Obstetrics and Gynaecology, DNB - Obstetrics and Gynaecology
Last update on 18-Nov-2024
